JP2012516145A5 - - Google Patents

Info

Publication number

JP2012516145A5

JP2012516145A5 JP2011546948A JP2011546948A JP2012516145A5 JP 2012516145 A5 JP2012516145 A5 JP 2012516145A5 JP 2011546948 A JP2011546948 A JP 2011546948A JP 2011546948 A JP2011546948 A JP 2011546948A JP 2012516145 A5 JP2012516145 A5 JP 2012516145A5

Authority

JP

Japan

Prior art keywords

component

group

linker

hybridizable

covalent bond

Prior art date

2010-01-29

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
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• 238000000034 method Methods 0.000 claims 15
• 239000002773 nucleotide Substances 0.000 claims 12
• 125000003729 nucleotide group Chemical group 0.000 claims 12
• 108700020942 nucleic acid binding protein Proteins 0.000 claims 7
• 102000044158 nucleic acid binding protein Human genes 0.000 claims 7
• 239000011148 porous material Substances 0.000 claims 6
• 108060002716 Exonuclease Proteins 0.000 claims 5
• 102000013165 exonuclease Human genes 0.000 claims 5
• 108091005703 transmembrane proteins Proteins 0.000 claims 5
• 102000035160 transmembrane proteins Human genes 0.000 claims 5
• 229920002684 Sepharose Polymers 0.000 claims 4
• 102000039446 nucleic acids Human genes 0.000 claims 4
• 150000007523 nucleic acids Chemical class 0.000 claims 4
• 108020004707 nucleic acids Proteins 0.000 claims 4
• 101710092462 Alpha-hemolysin Proteins 0.000 claims 3
• 230000015572 biosynthetic process Effects 0.000 claims 3
• 102000004169 proteins and genes Human genes 0.000 claims 3
• 108090000623 proteins and genes Proteins 0.000 claims 3
• -1 affinity tag Polymers 0.000 claims 2
• 239000011521 glass Substances 0.000 claims 2
• RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 claims 2
• 239000011159 matrix material Substances 0.000 claims 2
• 239000002184 metal Substances 0.000 claims 2
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 229920001353 Dextrin Polymers 0.000 claims 1
• 239000004375 Dextrin Substances 0.000 claims 1
• 108010024636 Glutathione Proteins 0.000 claims 1
• 108060004795 Methyltransferase Proteins 0.000 claims 1
• 101710163270 Nuclease Proteins 0.000 claims 1
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
• 101710183280 Topoisomerase Proteins 0.000 claims 1
• 125000002355 alkine group Chemical group 0.000 claims 1
• IVRMZWNICZWHMI-UHFFFAOYSA-N azide group Chemical group [N-]=[N+]=[N-] IVRMZWNICZWHMI-UHFFFAOYSA-N 0.000 claims 1
• 239000011324 bead Substances 0.000 claims 1
• 125000003636 chemical group Chemical group 0.000 claims 1
• 230000008878 coupling Effects 0.000 claims 1
• 238000010168 coupling process Methods 0.000 claims 1
• 238000005859 coupling reaction Methods 0.000 claims 1
• 235000019425 dextrin Nutrition 0.000 claims 1
• 239000010408 film Substances 0.000 claims 1
• 229960003180 glutathione Drugs 0.000 claims 1
• 239000004615 ingredient Substances 0.000 claims 1
• 238000005649 metathesis reaction Methods 0.000 claims 1
• 239000002105 nanoparticle Substances 0.000 claims 1
• 239000004033 plastic Substances 0.000 claims 1
• 229920000642 polymer Polymers 0.000 claims 1
• 229920001184 polypeptide Polymers 0.000 claims 1
• 102000004196 processed proteins & peptides Human genes 0.000 claims 1
• 108090000765 processed proteins & peptides Proteins 0.000 claims 1
• 125000006853 reporter group Chemical group 0.000 claims 1
• 239000011347 resin Substances 0.000 claims 1
• 229920005989 resin Polymers 0.000 claims 1
• 239000007787 solid Substances 0.000 claims 1