JP2012515722A - 抗原特異的寛容の誘導のための組成物および方法 - Google Patents

抗原特異的寛容の誘導のための組成物および方法 Download PDF

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JP2012515722A
JP2012515722A JP2011546446A JP2011546446A JP2012515722A JP 2012515722 A JP2012515722 A JP 2012515722A JP 2011546446 A JP2011546446 A JP 2011546446A JP 2011546446 A JP2011546446 A JP 2011546446A JP 2012515722 A JP2012515722 A JP 2012515722A
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antigen
composition
carrier
cells
peptide
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JP2012515722A5 (https=
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スティーブン ミラー，
ラッセル エル． ブロムレー，
マイケル エー． プレイス，
ダニエル ゲッツ，
アーロン マーティン，
Original Assignee
ノースウェスタン ユニバーシティ
ミエリン リペア ファウンデーション， インコーポレイテッド
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    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K39/0005—Vertebrate antigens
    • A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
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    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2011546446A 2009-01-20 2010-01-20 抗原特異的寛容の誘導のための組成物および方法 Pending JP2012515722A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14594109P 2009-01-20 2009-01-20
US61/145,941 2009-01-20
PCT/US2010/021547 WO2010085509A1 (en) 2009-01-20 2010-01-20 Compositions and methods for induction of antigen-specific tolerance

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JP2012515722A true JP2012515722A (ja) 2012-07-12
JP2012515722A5 JP2012515722A5 (https=) 2013-05-16

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US (4) US20120076831A1 (https=)
EP (1) EP2389193A4 (https=)
JP (1) JP2012515722A (https=)
KR (1) KR20110117684A (https=)
CN (1) CN102325546A (https=)
AU (1) AU2010206854A1 (https=)
CA (1) CA2750098A1 (https=)
IL (1) IL214163A0 (https=)
MX (1) MX2011007559A (https=)
SG (2) SG193843A1 (https=)
TW (1) TW201039843A (https=)
WO (1) WO2010085509A1 (https=)

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JP2016528254A (ja) * 2013-08-13 2016-09-15 ノースウエスタン ユニバーシティ ペプチドコンジュゲート粒子
JP2017527565A (ja) * 2014-09-07 2017-09-21 セレクタ バイオサイエンシーズ インコーポレーテッドＳｅｌｅｃｔａ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． 遺伝子発現調節抗ウイルス導入ベクター免疫応答を減弱化するための方法および組成物
JP2019031481A (ja) * 2017-08-08 2019-02-28 静岡県公立大学法人 自己免疫疾患の治療又は予防剤
US10668053B2 (en) 2013-05-03 2020-06-02 Selecta Biosciences, Inc. Tolerogenic synthetic nanocarriers to reduce or prevent anaphylaxis in response to a non-allergenic antigen
US11235057B2 (en) 2011-04-29 2022-02-01 Selecta Biosciences, Inc. Methods for providing polymeric synthetic nanocarriers for generating antigen-specific tolerance immune responses
US11426451B2 (en) 2017-03-11 2022-08-30 Selecta Biosciences, Inc. Methods and compositions related to combined treatment with antiinflammatories and synthetic nanocarriers comprising an immunosuppressant
JP2022541582A (ja) * 2019-07-19 2022-09-26 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 自己免疫障害を処置するための組成物および方法
US12553041B2 (en) 2019-06-04 2026-02-17 Cartesian Therapeutics Inc. Formulations and doses of pegylated uricase

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US20140105980A1 (en) * 2012-10-11 2014-04-17 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
EP2598120B1 (en) 2010-07-31 2018-09-05 The Scripps Research Institute Compositions and methods for inducing immune tolerance
US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
US9517257B2 (en) 2010-08-10 2016-12-13 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
WO2012021512A2 (en) 2010-08-10 2012-02-16 Ecole Polytechnique Federale De Lausanne Erythrocyte-binding therapeutics
JP5909745B2 (ja) * 2010-11-12 2016-04-27 クール ファーマシューティカルズ ディベロップメント カンパニー 炎症性疾患の治療薬、ならびにウイルスまたは細菌感染疾患の治療薬
US9511151B2 (en) 2010-11-12 2016-12-06 Uti Limited Partnership Compositions and methods for the prevention and treatment of cancer
EP2753362A4 (en) * 2011-09-08 2015-04-15 Univ Florida MATERIALS AND METHOD FOR MODULATING IMMUNE SYSTEM REACTIONS
US10988516B2 (en) 2012-03-26 2021-04-27 Uti Limited Partnership Methods and compositions for treating inflammation
US9597385B2 (en) 2012-04-23 2017-03-21 Allertein Therapeutics, Llc Nanoparticles for treatment of allergy
WO2013184976A2 (en) * 2012-06-06 2013-12-12 Northwestern University Compositions and methods for antigen-specific tolerance
WO2013192532A2 (en) 2012-06-21 2013-12-27 Northwestern University Peptide conjugated particles
US9603948B2 (en) 2012-10-11 2017-03-28 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
EP2928500B1 (en) 2012-12-04 2019-03-06 Phosphorex Inc. Microparticles and nanoparticles having negative surface charges
CN105263476A (zh) * 2013-03-13 2016-01-20 库尔制药开发公司 用于治疗炎症的免疫修饰性颗粒
CN105188741A (zh) 2013-04-03 2015-12-23 阿勒丁医疗公司 新型纳米颗粒组合物
IL295392A (en) 2013-06-04 2022-10-01 Selecta Biosciences Inc Repeated administration of non-immunosupressive antigen specific immunotherapeutics
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