JP2012515722A - 抗原特異的寛容の誘導のための組成物および方法 - Google Patents

抗原特異的寛容の誘導のための組成物および方法 Download PDF

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JP2012515722A
JP2012515722A JP2011546446A JP2011546446A JP2012515722A JP 2012515722 A JP2012515722 A JP 2012515722A JP 2011546446 A JP2011546446 A JP 2011546446A JP 2011546446 A JP2011546446 A JP 2011546446A JP 2012515722 A JP2012515722 A JP 2012515722A
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antigen
composition
carrier
cells
peptide
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JP2012515722A5 (enExample
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スティーブン ミラー,
ラッセル エル. ブロムレー,
マイケル エー. プレイス,
ダニエル ゲッツ,
アーロン マーティン,
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ノースウェスタン ユニバーシティ
ミエリン リペア ファウンデーション, インコーポレイテッド
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    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
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    • A61K47/6921Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
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  • Rheumatology (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2011546446A 2009-01-20 2010-01-20 抗原特異的寛容の誘導のための組成物および方法 Pending JP2012515722A (ja)

Applications Claiming Priority (3)

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US14594109P 2009-01-20 2009-01-20
US61/145,941 2009-01-20
PCT/US2010/021547 WO2010085509A1 (en) 2009-01-20 2010-01-20 Compositions and methods for induction of antigen-specific tolerance

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JP2012515722A true JP2012515722A (ja) 2012-07-12
JP2012515722A5 JP2012515722A5 (enExample) 2013-05-16

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US (4) US20120076831A1 (enExample)
EP (1) EP2389193A4 (enExample)
JP (1) JP2012515722A (enExample)
KR (1) KR20110117684A (enExample)
CN (1) CN102325546A (enExample)
AU (1) AU2010206854A1 (enExample)
CA (1) CA2750098A1 (enExample)
IL (1) IL214163A0 (enExample)
MX (1) MX2011007559A (enExample)
SG (2) SG173041A1 (enExample)
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JP2016528254A (ja) * 2013-08-13 2016-09-15 ノースウエスタン ユニバーシティ ペプチドコンジュゲート粒子
JP2017527571A (ja) * 2014-09-07 2017-09-21 セレクタ バイオサイエンシーズ インコーポレーテッドSelecta Biosciences,Inc. 遺伝子治療用抗ウイルス導入ベクター免疫応答を減弱化するための方法および組成物
JP2019031481A (ja) * 2017-08-08 2019-02-28 静岡県公立大学法人 自己免疫疾患の治療又は予防剤
US10668053B2 (en) 2013-05-03 2020-06-02 Selecta Biosciences, Inc. Tolerogenic synthetic nanocarriers to reduce or prevent anaphylaxis in response to a non-allergenic antigen
US11235057B2 (en) 2011-04-29 2022-02-01 Selecta Biosciences, Inc. Methods for providing polymeric synthetic nanocarriers for generating antigen-specific tolerance immune responses
US11426451B2 (en) 2017-03-11 2022-08-30 Selecta Biosciences, Inc. Methods and compositions related to combined treatment with antiinflammatories and synthetic nanocarriers comprising an immunosuppressant
JP2022541582A (ja) * 2019-07-19 2022-09-26 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 自己免疫障害を処置するための組成物および方法

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US20140105980A1 (en) * 2012-10-11 2014-04-17 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
US9522183B2 (en) 2010-07-31 2016-12-20 The Scripps Research Institute Compositions and methods for inducing immune tolerance
AU2011289579B2 (en) 2010-08-10 2016-11-17 Ecole Polytechnique Federale De Lausanne Erythrocyte-binding therapeutics
US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
US9517257B2 (en) 2010-08-10 2016-12-13 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
US9511151B2 (en) 2010-11-12 2016-12-06 Uti Limited Partnership Compositions and methods for the prevention and treatment of cancer
JP5909745B2 (ja) * 2010-11-12 2016-04-27 クール ファーマシューティカルズ ディベロップメント カンパニー 炎症性疾患の治療薬、ならびにウイルスまたは細菌感染疾患の治療薬
JP2014526472A (ja) 2011-09-08 2014-10-06 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド 免疫応答を調節するための材料および方法
US10988516B2 (en) 2012-03-26 2021-04-27 Uti Limited Partnership Methods and compositions for treating inflammation
US9597385B2 (en) 2012-04-23 2017-03-21 Allertein Therapeutics, Llc Nanoparticles for treatment of allergy
US20150150996A1 (en) * 2012-06-06 2015-06-04 Northwestern University Compositions and methods for antigen-specific tolerance
KR20250052503A (ko) 2012-06-21 2025-04-18 노쓰웨스턴유니버시티 펩티드 접합된 입자
US9603948B2 (en) 2012-10-11 2017-03-28 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
CA2932532C (en) 2012-12-04 2021-06-22 Phosphorex, Inc. Microparticles and nanoparticles having negative surface charges
HK1220368A1 (zh) * 2013-03-13 2017-05-05 Cour Pharmaceuticals Development Company 用於治疗炎症的免疫修饰性颗粒
EP3760223A1 (en) 2013-04-03 2021-01-06 N-Fold Llc Nanoparticle composition for desensitizing a subject to peanut allergens
KR102631173B1 (ko) 2013-06-04 2024-01-31 셀렉타 바이오사이언시즈, 인크. 비-면역억제성 항원 특이적 면역요법제의 반복 투여
EP3013362B1 (en) 2013-06-28 2021-08-04 Baylor Research Institute Dendritic cell asgpr targeting immunotherapeutics for multiple sclerosis
SG10201912301XA (en) 2013-11-04 2020-02-27 Uti Lp Methods and compositions for sustained immunotherapy
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