JP2012514006A5 - - Google Patents

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Publication number
JP2012514006A5
JP2012514006A5 JP2011543717A JP2011543717A JP2012514006A5 JP 2012514006 A5 JP2012514006 A5 JP 2012514006A5 JP 2011543717 A JP2011543717 A JP 2011543717A JP 2011543717 A JP2011543717 A JP 2011543717A JP 2012514006 A5 JP2012514006 A5 JP 2012514006A5
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JP
Japan
Prior art keywords
optionally substituted
disorder
hydrogen
carbons
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011543717A
Other languages
English (en)
Japanese (ja)
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JP2012514006A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2009/069716 external-priority patent/WO2010078348A1/en
Publication of JP2012514006A publication Critical patent/JP2012514006A/ja
Publication of JP2012514006A5 publication Critical patent/JP2012514006A5/ja
Pending legal-status Critical Current

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JP2011543717A 2008-12-29 2009-12-29 ３．１．０二環式ＧｌｙＴ１阻害剤ならびにその作製および使用の方法 Pending JP2012514006A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14103008P 2008-12-29 2008-12-29
US61/141,030 2008-12-29
PCT/US2009/069716 WO2010078348A1 (en) 2008-12-29 2009-12-29 3.1.0 bicyclic glyt1 inhibitors and methods of making and using same

Publications (2)

Publication Number Publication Date
JP2012514006A JP2012514006A (ja) 2012-06-21
JP2012514006A5 true JP2012514006A5 (https=) 2013-01-31

Family

ID=42310195

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011543717A Pending JP2012514006A (ja) 2008-12-29 2009-12-29 ３．１．０二環式ＧｌｙＴ１阻害剤ならびにその作製および使用の方法

Country Status (12)

Country Link
US (1) US8497289B2 (https=)
EP (1) EP2381941A4 (https=)
JP (1) JP2012514006A (https=)
KR (1) KR20110117087A (https=)
CN (1) CN102271677A (https=)
AU (1) AU2009335120A1 (https=)
BR (1) BRPI0923878A2 (https=)
CA (1) CA2747602A1 (https=)
IL (1) IL213541A0 (https=)
MX (1) MX2011006845A (https=)
RU (1) RU2011124709A (https=)
WO (1) WO2010078348A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9012489B2 (en) * 2011-08-03 2015-04-21 Boehringer Ingelheim International Gmbh Phenyl-3-aza-bicyclo[3.1.0]hex-3-yl-methanones and the use thereof as medicament
KR20170013890A (ko) * 2014-05-06 2017-02-07 노쓰웨스턴유니버시티 Nmdar 조절 화합물의 조합물
WO2016179351A1 (en) 2015-05-05 2016-11-10 Northwestern University Treatment of levodopa-induced dyskinesias
CN113784966B (zh) * 2019-05-01 2024-07-19 勃林格殷格翰国际有限公司 Glyt1抑制剂的固体形式
CA3188340A1 (en) 2020-08-13 2022-02-17 Boehringer Ingelheim International Gmbh Treatment of cognitive impairement associated with schizophrenia
CA3195702A1 (en) 2020-10-13 2022-04-21 Boehringer Ingelheim International Gmbh Process of reworking
EP4570804A1 (en) 2022-08-09 2025-06-18 Xizang Haisco Pharmaceutical Co., Ltd. Pde4b inhibitor and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981168A (en) * 1998-05-15 1999-11-09 The University Of British Columbia Method and composition for modulating amyloidosis
KR20060095865A (ko) 2003-10-14 2006-09-04 화이자 프로덕츠 인크. 글리신 수송 억제제로서의 비시클릭 [3.1.0] 유도체
JP5055493B2 (ja) * 2004-12-21 2012-10-24 メルク シャープ エンド ドーム リミテッド Ｇｌｙｔ１阻害薬としてのピペリジンおよびアゼチジン誘導体
EP1888525A1 (en) * 2005-05-03 2008-02-20 Ranbaxy Laboratories Limited 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives as muscarinic receptor antagonists
GB0523998D0 (en) 2005-11-25 2006-01-04 Merck Sharp & Dohme Therapeutic agents
TW200823227A (en) * 2006-09-29 2008-06-01 Actelion Pharmaceuticals Ltd 3-aza-bicyclo[3.1.0]hexane derivatives

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