JP2012509063A5 - - Google Patents
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- JP2012509063A5 JP2012509063A5 JP2011536392A JP2011536392A JP2012509063A5 JP 2012509063 A5 JP2012509063 A5 JP 2012509063A5 JP 2011536392 A JP2011536392 A JP 2011536392A JP 2011536392 A JP2011536392 A JP 2011536392A JP 2012509063 A5 JP2012509063 A5 JP 2012509063A5
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- JP
- Japan
- Prior art keywords
- target
- reaction
- molecule
- target molecule
- reaction mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000006243 chemical reaction Methods 0.000 claims 48
- 239000000523 sample Substances 0.000 claims 38
- 239000011541 reaction mixture Substances 0.000 claims 29
- 230000009870 specific binding Effects 0.000 claims 14
- 238000000034 method Methods 0.000 claims 13
- 239000006249 magnetic particle Substances 0.000 claims 8
- 239000000758 substrate Substances 0.000 claims 8
- 230000015572 biosynthetic process Effects 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 239000002245 particle Substances 0.000 claims 3
- 230000008878 coupling Effects 0.000 claims 2
- 238000010168 coupling process Methods 0.000 claims 2
- 238000005859 coupling reaction Methods 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- 150000001345 alkine derivatives Chemical class 0.000 claims 1
- 150000001540 azides Chemical group 0.000 claims 1
- 238000006664 bond formation reaction Methods 0.000 claims 1
- 239000003054 catalyst Substances 0.000 claims 1
- 239000003431 cross linking reagent Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11540108P | 2008-11-17 | 2008-11-17 | |
| US61/115,401 | 2008-11-17 | ||
| PCT/US2009/063280 WO2010056579A1 (en) | 2008-11-17 | 2009-11-04 | Methods and compositions in particle-based detection of target molecules using covalent bond forming reactive pairs |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012509063A JP2012509063A (ja) | 2012-04-19 |
| JP2012509063A5 true JP2012509063A5 (cg-RX-API-DMAC7.html) | 2012-12-20 |
| JP5744743B2 JP5744743B2 (ja) | 2015-07-08 |
Family
ID=41467180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011536392A Expired - Fee Related JP5744743B2 (ja) | 2008-11-17 | 2009-11-04 | 共有結合形成反応ペアを用いた標的分子の粒子ベースの検出における方法および組成物 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9469868B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2358898B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5744743B2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010056579A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5850746B2 (ja) * | 2008-11-17 | 2016-02-03 | ヘッドウェイ テクノロジーズ, インク.Headway Technologies, Inc. | 連結分子を用いた標的分子の粒子ベースの検出における方法および組成物 |
| WO2012112563A2 (en) | 2011-02-16 | 2012-08-23 | Magic Technologies, Inc. | Methods and compositions for the target-localized anchoring of detectable label |
| EP2743682B1 (en) | 2011-08-11 | 2017-05-31 | Olympus Corporation | Method for detecting target particles |
| JP6010034B2 (ja) | 2011-08-30 | 2016-10-19 | オリンパス株式会社 | 標的粒子の検出方法 |
| CN104115003B (zh) | 2012-02-22 | 2016-03-23 | 奥林巴斯株式会社 | 目标粒子的检测方法 |
| JP6095645B2 (ja) | 2012-03-21 | 2017-03-15 | オリンパス株式会社 | 標的核酸分子の検出方法 |
| CN104428424A (zh) * | 2012-08-31 | 2015-03-18 | 东丽株式会社 | 目标核酸的检测方法 |
| US20160258938A1 (en) * | 2015-03-04 | 2016-09-08 | Headway Technologies, Inc. | Method of detecting an analyte in a sample |
| ES2702432B2 (es) * | 2017-08-31 | 2019-08-05 | Venegas Pedro Manuel Medina | Método y dispositivo para el análisis de ácidos nucleicos |
| CN116113710A (zh) * | 2020-09-17 | 2023-05-12 | 横河电机株式会社 | 核酸序列测定方法以及核酸序列测定用试剂盒 |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4599303A (en) | 1983-12-12 | 1986-07-08 | Hri Associates, Inc. | Nucleic acid hybridization assay employing probes crosslinkable to target sequences |
| US4826967A (en) | 1987-06-16 | 1989-05-02 | Naxcor | Psoralen-nucleoside adducts and method for their preparation |
| US5124246A (en) | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| US5512439A (en) | 1988-11-21 | 1996-04-30 | Dynal As | Oligonucleotide-linked magnetic particles and uses thereof |
| US5028594A (en) | 1988-12-27 | 1991-07-02 | Naxcor | Use of photodynamic compositions for cytotoxic effects |
| ES2063347T3 (es) | 1989-03-29 | 1995-01-01 | Du Pont | Deposicion catalizada de indicador. |
| US5196306A (en) | 1989-03-29 | 1993-03-23 | E. I. Du Pont De Nemours And Company | Method for the detection or quantitation of an analyte using an analyte dependent enzyme activation system |
| US5082934A (en) | 1989-04-05 | 1992-01-21 | Naxcor | Coumarin derivatives for use as nucleotide crosslinking reagents |
| US7223833B1 (en) | 1991-05-24 | 2007-05-29 | Isis Pharmaceuticals, Inc. | Peptide nucleic acid conjugates |
| GB9301122D0 (en) | 1993-01-21 | 1993-03-10 | Scient Generics Ltd | Method of analysis/separation |
| US5616464A (en) | 1994-12-27 | 1997-04-01 | Naxcor | Nucleic acid sequence detection employing amplification probes |
| EP0693065B1 (en) | 1993-04-13 | 2001-12-05 | Naxcor | Non-nucleosidic coumarin derivatives as polynucleotide-crosslinking agents |
| US6277570B1 (en) | 1993-04-13 | 2001-08-21 | Naxcor | Nucleic acid sequence detection employing probes comprising non-nucleosidic coumarin derivatives as polynucleotide-crosslinking agents |
| US6495676B1 (en) | 1993-04-13 | 2002-12-17 | Naxcor | Nucleic acid sequence detection employing probes comprising non-nucleosidic coumarin derivatives as polynucleotide-crosslinking agents |
| US5767259A (en) | 1994-12-27 | 1998-06-16 | Naxcor | Oligonucleotides containing base-free linking groups with photoactivatable side chains |
| US5681697A (en) * | 1993-12-08 | 1997-10-28 | Chiron Corporation | Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor |
| US5580731A (en) | 1994-08-25 | 1996-12-03 | Chiron Corporation | N-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewith |
| WO1997027317A1 (en) | 1996-01-23 | 1997-07-31 | Affymetrix, Inc. | Nucleic acid analysis techniques |
| JPH11514525A (ja) | 1995-11-03 | 1999-12-14 | ナックスコー | 二本鎖高次構造多型分析 |
| US6582921B2 (en) | 1996-07-29 | 2003-06-24 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses thereof |
| US6506564B1 (en) * | 1996-07-29 | 2003-01-14 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| US5981297A (en) | 1997-02-05 | 1999-11-09 | The United States Of America As Represented By The Secretary Of The Navy | Biosensor using magnetically-detected label |
| AU5779399A (en) * | 1998-08-21 | 2000-03-27 | Naxcor | Assays using crosslinkable immobilized nucleic acids |
| US6303799B1 (en) | 1998-11-10 | 2001-10-16 | Naxcor | Polynucleotide crosslinking agents |
| US20020051971A1 (en) | 1999-05-21 | 2002-05-02 | John R. Stuelpnagel | Use of microfluidic systems in the detection of target analytes using microsphere arrays |
| US6743639B1 (en) | 1999-10-13 | 2004-06-01 | Nve Corporation | Magnetizable bead detector |
| US6875621B2 (en) | 1999-10-13 | 2005-04-05 | Nve Corporation | Magnetizable bead detector |
| US6770441B2 (en) | 2000-02-10 | 2004-08-03 | Illumina, Inc. | Array compositions and methods of making same |
| US6573048B1 (en) | 2000-04-18 | 2003-06-03 | Naxcor | Degradable nucleic acid probes and nucleic acid detection methods |
| ATE364722T1 (de) | 2000-06-02 | 2007-07-15 | Bayer Corp | Verfahren zum nachweis und zur lokalisierung von genen in situ durch hybridisierung einer verzweigten dna |
| AU2002339853A1 (en) | 2001-05-24 | 2002-12-03 | Genospectra, Inc. | Pairs of nucleic acid probes with interactive signaling moieties and nucleic acid probes with enhanced hybridization efficiency and specificity |
| US20070184436A1 (en) | 2001-06-07 | 2007-08-09 | Joel Myerson | Generic capture probe arrays |
| AU2002353996A1 (en) | 2001-11-01 | 2003-05-12 | Rensselaer Polytechnic Institute | Solid-phase array-based biocatalytic transformations |
| US8043868B2 (en) | 2001-12-21 | 2011-10-25 | Imec | Method and apparatus for detecting an analyte |
| CA2480673A1 (en) | 2002-03-29 | 2003-10-09 | Genentech, Inc. | Methods and compositions for detection and quantitation of nucleic acid analytes |
| AUPS159702A0 (en) | 2002-04-09 | 2002-05-16 | Tong, Sun Wing | Molecular detection and assay by magneto-thermal biochip micro-assay |
| US6800768B1 (en) * | 2002-09-06 | 2004-10-05 | Naxcor, Inc. | Non-nucleosidic coumarin derivatives as polynucleotide-crosslinking agents |
| EP1565480B1 (en) | 2002-11-22 | 2018-08-22 | Roche Diagnostics GmbH | Detectable labeled nucleoside analogs and methods of use thereof |
| CN1580283A (zh) | 2003-08-13 | 2005-02-16 | 清华大学 | 一种检测核酸分子的方法 |
| JP2007508020A (ja) * | 2003-09-30 | 2007-04-05 | カイロン コーポレイション | ヒトdkkl1の新規スプライス改変体 |
| US7906345B2 (en) | 2003-11-12 | 2011-03-15 | The Board Of Trustees Of The Leland Stanford Junior University | Magnetic nanoparticles, magnetic detector arrays, and methods for their use in detecting biological molecules |
| US7332355B2 (en) | 2003-11-18 | 2008-02-19 | California Institute Of Technology | Method and compositions for the detection of protein glycosylation |
| US7435386B2 (en) | 2004-03-25 | 2008-10-14 | The United States Of America As Represented By The Secretary Of The Navy | Reagentless and reusable biosensors with tunable differential binding affinities and methods of making |
| US20060177850A1 (en) * | 2004-12-30 | 2006-08-10 | Mack Schermer | Particle-based multiplex assay system with three or more assay reporters |
| ATE551433T1 (de) | 2005-05-06 | 2012-04-15 | Gen Probe Inc | Verfahren und produkte zum erfassen von nukleinsäurezielen |
| US7803541B2 (en) | 2005-05-12 | 2010-09-28 | Panomics, Inc. | Multiplex branched-chain DNA assays |
| DK2500439T4 (da) | 2005-06-20 | 2017-11-13 | Advanced Cell Diagnostics Inc | Kits og produkter til detektering af nukleinsyrer i individuelle celler og til identifikation af sjældne celler fra store heterogene cellepopulationer |
| CA2613101A1 (en) | 2005-07-01 | 2007-01-11 | Bioveris Corporation | Compositions and methods for detecting, amplifying, and/or isolating nucleic acids |
| WO2007056250A2 (en) * | 2005-11-04 | 2007-05-18 | U.S. Genomics, Inc. | Heterogeneous assay of analytes in solution using polymers |
| JP2007189991A (ja) | 2006-01-20 | 2007-08-02 | Nippon Meat Packers Inc | 遺伝子の検出方法 |
| JP2007225586A (ja) | 2006-01-27 | 2007-09-06 | Seiko Instruments Inc | タンパク質の固定化方法 |
| US8114636B2 (en) * | 2006-02-10 | 2012-02-14 | Life Technologies Corporation | Labeling and detection of nucleic acids |
| ATE515488T1 (de) | 2006-10-31 | 2011-07-15 | Baseclick Gmbh | Click-chemie zur herstellung von reportermolekülen |
| EP2195461B1 (en) | 2007-09-17 | 2015-05-27 | Mattias Strömberg | Magnetic detection of small entities |
| US20090111709A1 (en) | 2007-09-18 | 2009-04-30 | Burke Thomas J | Affinity Measurements Using Frameless Multiplexed Microarrays |
| CN101868286A (zh) | 2007-09-20 | 2010-10-20 | 马格雷股份有限公司 | 采用磁性传感器进行的分析物检测 |
| GB0804495D0 (en) | 2008-03-11 | 2008-04-16 | Iti Scotland Ltd | Surface attachment |
| JP5850746B2 (ja) | 2008-11-17 | 2016-02-03 | ヘッドウェイ テクノロジーズ, インク.Headway Technologies, Inc. | 連結分子を用いた標的分子の粒子ベースの検出における方法および組成物 |
| WO2012112563A2 (en) | 2011-02-16 | 2012-08-23 | Magic Technologies, Inc. | Methods and compositions for the target-localized anchoring of detectable label |
-
2009
- 2009-11-04 JP JP2011536392A patent/JP5744743B2/ja not_active Expired - Fee Related
- 2009-11-04 WO PCT/US2009/063280 patent/WO2010056579A1/en not_active Ceased
- 2009-11-04 EP EP09760043.1A patent/EP2358898B1/en not_active Not-in-force
- 2009-11-04 US US12/612,432 patent/US9469868B2/en not_active Expired - Fee Related
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