JP2012507317A - 骨固定システム - Google Patents
骨固定システム Download PDFInfo
- Publication number
- JP2012507317A JP2012507317A JP2011533825A JP2011533825A JP2012507317A JP 2012507317 A JP2012507317 A JP 2012507317A JP 2011533825 A JP2011533825 A JP 2011533825A JP 2011533825 A JP2011533825 A JP 2011533825A JP 2012507317 A JP2012507317 A JP 2012507317A
- Authority
- JP
- Japan
- Prior art keywords
- sleeve
- rod
- fixation
- rods
- vertebrae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
- A61B17/7002—Longitudinal elements, e.g. rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
- A61B17/7002—Longitudinal elements, e.g. rods
- A61B17/7019—Longitudinal elements having flexible parts, or parts connected together, such that after implantation the elements can move relative to each other
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
- A61B17/7002—Longitudinal elements, e.g. rods
- A61B17/7019—Longitudinal elements having flexible parts, or parts connected together, such that after implantation the elements can move relative to each other
- A61B17/702—Longitudinal elements having flexible parts, or parts connected together, such that after implantation the elements can move relative to each other having a core or insert, and a sleeve, whereby a screw or hook can move along the core or in the sleeve
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
- A61B17/7002—Longitudinal elements, e.g. rods
- A61B17/7019—Longitudinal elements having flexible parts, or parts connected together, such that after implantation the elements can move relative to each other
- A61B17/7025—Longitudinal elements having flexible parts, or parts connected together, such that after implantation the elements can move relative to each other with a sliding joint
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7049—Connectors, not bearing on the vertebrae, for linking longitudinal elements together
- A61B17/705—Connectors, not bearing on the vertebrae, for linking longitudinal elements together for linking adjacent ends of longitudinal elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
- A61B17/7002—Longitudinal elements, e.g. rods
- A61B17/701—Longitudinal elements with a non-circular, e.g. rectangular, cross-section
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
- A61B17/7002—Longitudinal elements, e.g. rods
- A61B17/7011—Longitudinal element being non-straight, e.g. curved, angled or branched
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
- A61B17/7032—Screws or hooks with U-shaped head or back through which longitudinal rods pass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7049—Connectors, not bearing on the vertebrae, for linking longitudinal elements together
Landscapes
- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0820252.5A GB2465156B (en) | 2008-11-05 | 2008-11-05 | Bone fixation system |
| GB0820252.5 | 2008-11-05 | ||
| PCT/GB2009/002616 WO2010052465A1 (en) | 2008-11-05 | 2009-11-05 | Bone fixation system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012507317A true JP2012507317A (ja) | 2012-03-29 |
| JP2012507317A5 JP2012507317A5 (enExample) | 2012-12-20 |
Family
ID=40138356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011533825A Pending JP2012507317A (ja) | 2008-11-05 | 2009-11-05 | 骨固定システム |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20110282391A1 (enExample) |
| EP (1) | EP2344057B1 (enExample) |
| JP (1) | JP2012507317A (enExample) |
| GB (1) | GB2465156B (enExample) |
| WO (1) | WO2010052465A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8100946B2 (en) | 2005-11-21 | 2012-01-24 | Synthes Usa, Llc | Polyaxial bone anchors with increased angulation |
| US9439681B2 (en) | 2007-07-20 | 2016-09-13 | DePuy Synthes Products, Inc. | Polyaxial bone fixation element |
| US9050141B2 (en) * | 2008-02-02 | 2015-06-09 | Texas Scottish Rite Hospital For Children | Pedicle screw |
| US9345517B2 (en) * | 2008-02-02 | 2016-05-24 | Globus Medical, Inc. | Pedicle screw having a removable rod coupling |
| US20100049252A1 (en) * | 2008-08-21 | 2010-02-25 | Southern Spine, Llc | Transverse Connector Device for Extending an Existing Spinal Fixation System |
| ATE548982T1 (de) | 2008-09-12 | 2012-03-15 | Synthes Gmbh | System zur wirbelsäulenstabilisierung und richtfixierung |
| DE09793113T8 (de) | 2008-09-29 | 2013-04-25 | Synthes Gmbh | Polyaxiale bodenladungsschraube und stangenanordnung |
| US8628558B2 (en) | 2008-11-03 | 2014-01-14 | DePuy Synthes Products, LLC | Uni-planer bone fixation assembly |
| CA2758590A1 (en) | 2009-04-15 | 2010-10-21 | Synthes Usa, Llc | Revision connector for spinal constructs |
| JP5654584B2 (ja) | 2009-06-17 | 2015-01-14 | ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 脊柱構築用の修正コネクタ |
| GB0915382D0 (en) | 2009-09-03 | 2009-10-07 | Dalmatic As | Expansion devices |
| US20110098748A1 (en) * | 2009-10-26 | 2011-04-28 | Warsaw Orthopedic, Inc. | Adjustable vertebral rod system and methods of use |
| CA2782381A1 (en) | 2009-12-01 | 2011-06-09 | Synthes Usa, Llc | Non-fusion scoliosis expandable spinal rod |
| US8961567B2 (en) | 2010-11-22 | 2015-02-24 | DePuy Synthes Products, LLC | Non-fusion scoliosis expandable spinal rod |
| EP2460482A1 (en) * | 2010-12-03 | 2012-06-06 | Zimmer Spine | Rod holding device |
| WO2012106646A2 (en) * | 2011-02-05 | 2012-08-09 | Alphatec Spine, Inc. | Semi-rigid screw assembly |
| EP2662037B1 (en) * | 2012-05-09 | 2023-01-11 | CoLigne AG | Iliac connector, connector head and spinal fixation system |
| US10265103B2 (en) * | 2016-08-18 | 2019-04-23 | Premia Spine Ltd. | Spinal prosthesis with adjustable support element |
| US11737793B2 (en) * | 2017-10-20 | 2023-08-29 | Mayo Foundation For Medical Education And Research | Facet joint replacement devices |
| US12082849B2 (en) | 2019-04-12 | 2024-09-10 | Orthopediatrics Corp. | Dual tether support of vertebra |
| US11684395B2 (en) * | 2019-05-22 | 2023-06-27 | Nuvasive, Inc. | Posterior spinal fixation screws |
| US11426211B2 (en) * | 2020-10-28 | 2022-08-30 | Globus Medical, Inc. | Articulating connectors, systems, and methods thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0956736A (ja) * | 1995-08-25 | 1997-03-04 | Tanaka Ika Kikai Seisakusho:Kk | 脊柱変形の矯正装置 |
| WO2007061960A2 (en) * | 2005-11-18 | 2007-05-31 | Life Spine, Inc. | Dynamic spinal stabilization devices and systems |
| WO2008051806A2 (en) * | 2006-10-19 | 2008-05-02 | Simpirica Spine, Inc. | Methods and systems for laterally stabilized constraint of spinous processes |
| WO2008078163A2 (en) * | 2006-12-21 | 2008-07-03 | Ldr Medical | Vertebral support device |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3306657C2 (de) * | 1983-02-25 | 1986-12-11 | Fa. Heinrich C. Ulrich, 7900 Ulm | Implantat zur Wirbelsäulenkorrektur mit einem Distraktionsstab |
| US4620533A (en) | 1985-09-16 | 1986-11-04 | Pfizer Hospital Products Group Inc. | External bone fixation apparatus |
| US4771767A (en) | 1986-02-03 | 1988-09-20 | Acromed Corporation | Apparatus and method for maintaining vertebrae in a desired relationship |
| FR2720261B1 (fr) | 1994-05-27 | 1996-09-13 | Pascal Aufaure | Implant pour dispositif d'ostéosynthèse. |
| FR2724553B1 (fr) | 1994-09-15 | 1996-12-20 | Tornier Sa | Fixateur externe ou interne destine a la reparation des fractures ou des arthroplasties du squelette |
| US5620443A (en) * | 1995-01-25 | 1997-04-15 | Danek Medical, Inc. | Anterior screw-rod connector |
| FR2731344B1 (fr) | 1995-03-06 | 1997-08-22 | Dimso Sa | Instrumentation rachidienne notamment pour tige |
| JPH10171304A (ja) | 1996-03-14 | 1998-06-26 | Matsushita Electric Ind Co Ltd | カラー画像形成装置 |
| JP3172703B2 (ja) | 1997-12-18 | 2001-06-04 | 株式会社ロバート・リード商会 | 骨固定装置 |
| CA2330802A1 (fr) | 1998-04-29 | 1999-11-04 | Dimso (Distribution Medicale Du Sud-Ouest) | Systeme d'osteosynthese rachidienne avec moyens de serrage notamment pour une fixation anterieure |
| FR2794357B1 (fr) * | 1999-06-01 | 2001-09-14 | Frederic Fortin | Dispositif de distraction pour les os d'enfants possedant des moyens d'accrochage et de reglage permettant de suivre leur croissance |
| US6524315B1 (en) | 2000-08-08 | 2003-02-25 | Depuy Acromed, Inc. | Orthopaedic rod/plate locking mechanism |
| US6565564B2 (en) | 2000-12-14 | 2003-05-20 | Synthes U.S.A. | Multi-pin clamp and rod attachment |
| US6802844B2 (en) | 2001-03-26 | 2004-10-12 | Nuvasive, Inc | Spinal alignment apparatus and methods |
| FR2827498B1 (fr) * | 2001-07-18 | 2004-05-14 | Frederic Fortin | Dispositif de liaison vertebrale souple constitue d'elements palliant une deficience du rachis |
| JP4332426B2 (ja) | 2001-10-23 | 2009-09-16 | ビーダーマン・モテーク・ゲゼルシャフト・ミット・ベシュレンクタ・ハフツング | 骨を固定するための装置、およびその装置用ねじ |
| US20060079892A1 (en) | 2001-10-31 | 2006-04-13 | Suranjan Roychowdhury | Adjustable tandem connectors for corrective devices for the spinal column and other bones and joints |
| FR2832620B1 (fr) | 2001-11-27 | 2004-01-23 | Eurosurgical | Connecteur pour systeme d'ancrage vertebral |
| US20040111088A1 (en) | 2002-12-06 | 2004-06-10 | Picetti George D. | Multi-rod bone attachment member |
| US8052723B2 (en) * | 2003-08-05 | 2011-11-08 | Flexuspine Inc. | Dynamic posterior stabilization systems and methods of use |
| US7819902B2 (en) | 2004-02-27 | 2010-10-26 | Custom Spine, Inc. | Medialised rod pedicle screw assembly |
| US7648520B2 (en) | 2004-04-16 | 2010-01-19 | Kyphon Sarl | Pedicle screw assembly |
| WO2006004468A1 (en) * | 2004-07-02 | 2006-01-12 | Volvo Technology Corporation | Internal combustion engine exhaust gas system |
| US7854752B2 (en) * | 2004-08-09 | 2010-12-21 | Theken Spine, Llc | System and method for dynamic skeletal stabilization |
| WO2006033503A1 (en) * | 2004-09-22 | 2006-03-30 | Kyung-Woo Park | Bio-flexible spinal fixation apparatus with shape memory alloy |
| US8162985B2 (en) * | 2004-10-20 | 2012-04-24 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for posterior dynamic stabilization of the spine |
| US20060265074A1 (en) * | 2004-10-21 | 2006-11-23 | Manoj Krishna | Posterior spinal arthroplasty-development of a new posteriorly inserted artificial disc, a new anteriorly inserted artifical disc and an artificial facet joint |
| DE202005005444U1 (de) | 2005-04-01 | 2005-06-02 | Tantum Ag | Fixationseinrichtung zum stabilen Verbinden wenigstens zweier Knochenteile eines gebrochenen Knochens sowie Fixationselement und Bausatz |
| ES2436101T3 (es) | 2005-10-07 | 2013-12-27 | Alphatec Spine, Inc. | Placa occipital ajustable |
| GB0521582D0 (en) * | 2005-10-22 | 2005-11-30 | Depuy Int Ltd | An implant for supporting a spinal column |
| US7803174B2 (en) | 2005-11-04 | 2010-09-28 | Warsaw Orthopedic, Inc. | Dorsal adjusting multi-rod connector |
| US7585299B2 (en) | 2006-02-17 | 2009-09-08 | Warsaw Orthopedic, Inc. | Dorsal adjusting spinal connector assembly |
| EP1857064A1 (en) * | 2006-05-15 | 2007-11-21 | Biomet Spain Orthopaedics S.L. | Surgical screw system |
| US8475499B2 (en) * | 2006-07-14 | 2013-07-02 | DePuy Synthes Products, LLC. | Rod to rod connectors and methods of adjusting the length of a spinal rod construct |
| US20080058805A1 (en) * | 2006-08-28 | 2008-03-06 | Microdexterity Systems, Inc. | Spinal fusion implant |
| US8109975B2 (en) * | 2007-01-30 | 2012-02-07 | Warsaw Orthopedic, Inc. | Collar bore configuration for dynamic spinal stabilization assembly |
| EP2301456B1 (en) * | 2007-02-23 | 2013-04-17 | Biedermann Technologies GmbH & Co. KG | Rod connector for stabilizing vertebrae |
| US8337527B2 (en) | 2007-04-18 | 2012-12-25 | Ebi, Llc | Spinal connector |
| AU2009212126A1 (en) * | 2008-02-07 | 2009-08-13 | K2M, Inc. | Automatic lengthening bone fixation device |
| US20090264931A1 (en) | 2008-04-18 | 2009-10-22 | Warsaw Orthopedic, Inc. | Implantable Article for Use with an Anchor and a Non-Metal Rod |
| US8197516B2 (en) * | 2008-07-01 | 2012-06-12 | The University Of Toledo | Lateral fixation assembly for spinal column |
| EP2174608B1 (en) * | 2008-10-08 | 2012-08-01 | Biedermann Technologies GmbH & Co. KG | Bone anchoring device and stabilization device for bone parts or vertebrae |
-
2008
- 2008-11-05 GB GB0820252.5A patent/GB2465156B/en not_active Expired - Fee Related
-
2009
- 2009-11-05 JP JP2011533825A patent/JP2012507317A/ja active Pending
- 2009-11-05 WO PCT/GB2009/002616 patent/WO2010052465A1/en not_active Ceased
- 2009-11-05 US US13/127,773 patent/US20110282391A1/en not_active Abandoned
- 2009-11-05 EP EP09753177.6A patent/EP2344057B1/en not_active Not-in-force
-
2014
- 2014-04-15 US US14/253,480 patent/US9439679B2/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0956736A (ja) * | 1995-08-25 | 1997-03-04 | Tanaka Ika Kikai Seisakusho:Kk | 脊柱変形の矯正装置 |
| WO2007061960A2 (en) * | 2005-11-18 | 2007-05-31 | Life Spine, Inc. | Dynamic spinal stabilization devices and systems |
| WO2008051806A2 (en) * | 2006-10-19 | 2008-05-02 | Simpirica Spine, Inc. | Methods and systems for laterally stabilized constraint of spinous processes |
| WO2008078163A2 (en) * | 2006-12-21 | 2008-07-03 | Ldr Medical | Vertebral support device |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2465156A8 (en) | 2012-10-03 |
| US9439679B2 (en) | 2016-09-13 |
| GB2465156A (en) | 2010-05-12 |
| EP2344057B1 (en) | 2017-05-10 |
| GB2465156B (en) | 2012-09-26 |
| US20110282391A1 (en) | 2011-11-17 |
| US20140228888A1 (en) | 2014-08-14 |
| WO2010052465A1 (en) | 2010-05-14 |
| GB0820252D0 (en) | 2008-12-10 |
| EP2344057A1 (en) | 2011-07-20 |
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