JP2012180344A5 - - Google Patents

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Publication number
JP2012180344A5
JP2012180344A5 JP2012023811A JP2012023811A JP2012180344A5 JP 2012180344 A5 JP2012180344 A5 JP 2012180344A5 JP 2012023811 A JP2012023811 A JP 2012023811A JP 2012023811 A JP2012023811 A JP 2012023811A JP 2012180344 A5 JP2012180344 A5 JP 2012180344A5
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JP
Japan
Prior art keywords
alkyl
membered
haloalkyl
membered heterocyclyl
aryl
Prior art date
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Application number
JP2012023811A
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English (en)
Japanese (ja)
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JP2012180344A (ja
JP5620417B2 (ja
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Priority to JP2012023811A priority Critical patent/JP5620417B2/ja
Priority claimed from JP2012023811A external-priority patent/JP5620417B2/ja
Publication of JP2012180344A publication Critical patent/JP2012180344A/ja
Publication of JP2012180344A5 publication Critical patent/JP2012180344A5/ja
Application granted granted Critical
Publication of JP5620417B2 publication Critical patent/JP5620417B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2012023811A 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬 Expired - Fee Related JP5620417B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2012023811A JP5620417B2 (ja) 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011024078 2011-02-07
JP2011024078 2011-02-07
JP2012023811A JP5620417B2 (ja) 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬

Publications (3)

Publication Number Publication Date
JP2012180344A JP2012180344A (ja) 2012-09-20
JP2012180344A5 true JP2012180344A5 (OSRAM) 2014-10-02
JP5620417B2 JP5620417B2 (ja) 2014-11-05

Family

ID=47011846

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012023811A Expired - Fee Related JP5620417B2 (ja) 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬

Country Status (1)

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JP (1) JP5620417B2 (OSRAM)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3015953B1 (ja) 1998-10-06 2000-03-06 株式会社ワールド・ブリック れんが壁
CN107501413A (zh) 2012-09-27 2017-12-22 中外制药株式会社 Fgfr3融合基因和以其作为标靶的药物
CN103224479B (zh) * 2013-04-26 2014-10-15 温州大学 一种2-芳基苯并呋喃类化合物的合成方法
EP2886118B1 (en) 2013-07-31 2018-09-05 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical preparation comprising aminopyrazole derivative
MX367723B (es) * 2013-10-25 2019-09-03 Novartis Ag Compuestos de anillos fusionados bicíclicos derivados de piridilo como inhibidores de fgfr4.
US9802920B2 (en) 2013-12-13 2017-10-31 Hoffman-La Roche Inc. Inhibitors of bruton's tyrosine kinase
JP6219523B2 (ja) 2013-12-13 2017-10-25 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ブルトンチロシンキナーゼの阻害剤
TW201609093A (zh) * 2013-12-27 2016-03-16 Chugai Pharmaceutical Co Ltd Ｆｇｆｒ門控蛋白變異基因及以其爲標的之醫藥
JP2017516463A (ja) * 2014-03-31 2017-06-22 デバイオファーム インターナショナル エスエイ Ｆｇｆｒ融合体
EP3200786B1 (en) 2014-10-03 2019-08-28 Novartis AG Use of ring-fused bicyclic pyridyl derivatives as fgfr4 inhibitors
US9802917B2 (en) * 2015-03-25 2017-10-31 Novartis Ag Particles of N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide
WO2016204261A1 (ja) * 2015-06-17 2016-12-22 中外製薬株式会社 アミノピラゾール誘導体
EP3339305B1 (en) * 2015-08-20 2022-05-04 Zhejiang Hisun Pharmaceutical Co., Ltd Indole derivative, preparation method thereof, and use thereof in pharmaceutical drug
CN110950848B (zh) * 2018-09-27 2024-03-26 徐诺药业 新型氨基吡唑类衍生物的合成与应用
EP3898626A1 (en) * 2018-12-19 2021-10-27 Array Biopharma, Inc. Substituted pyrazolo[1,5-a]pyridine compounds as inhibitors of fgfr tyrosine kinases
JP2022515197A (ja) 2018-12-19 2022-02-17 アレイ バイオファーマ インコーポレイテッド がんを治療するためのｆｇｆｒ阻害剤としての７－（（３，５－ジメトキシフェニル）アミノ）キノキサリン誘導体
CN112358435B (zh) * 2019-10-12 2023-01-10 中国医学科学院医药生物技术研究所 取代芳并杂环类化合物、制备方法和抑制ulk1及抗肿瘤用途
CA3228456A1 (en) * 2021-12-13 2023-06-22 Abbisko Therapeutics Co., Ltd. Fgfr4 inhibitor acid salt, preparation method therefor and use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6316466B1 (en) * 1998-05-05 2001-11-13 Syntex (U.S.A.) Llc Pyrazole derivatives P-38 MAP kinase inhibitors
IL139169A0 (en) * 1998-05-05 2001-11-25 Hoffmann La Roche Pyrazole derivatives as p-38 map kinase inhibitors
WO2005009973A1 (en) * 2003-06-26 2005-02-03 Novartis Ag 5-membered heterocycle-based p38 kinase inhibitors
ES2383273T3 (es) * 2008-07-23 2012-06-19 F. Hoffmann-La Roche Ag Compuestos heterocíclicos antivíricos

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