JP2012140432A5 - - Google Patents
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- Publication number
- JP2012140432A5 JP2012140432A5 JP2012015294A JP2012015294A JP2012140432A5 JP 2012140432 A5 JP2012140432 A5 JP 2012140432A5 JP 2012015294 A JP2012015294 A JP 2012015294A JP 2012015294 A JP2012015294 A JP 2012015294A JP 2012140432 A5 JP2012140432 A5 JP 2012140432A5
- Authority
- JP
- Japan
- Prior art keywords
- heterocyclyl
- cycloalkyl
- alkyl
- heteroaryl
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000000753 cycloalkyl group Chemical group 0.000 claims 17
- 125000000623 heterocyclic group Chemical group 0.000 claims 17
- 125000001072 heteroaryl group Chemical group 0.000 claims 16
- 125000000217 alkyl group Chemical group 0.000 claims 14
- 125000003118 aryl group Chemical group 0.000 claims 14
- 125000003342 alkenyl group Chemical group 0.000 claims 12
- 125000000304 alkynyl group Chemical group 0.000 claims 11
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 6
- 125000003545 alkoxy group Chemical group 0.000 claims 5
- 150000004678 hydrides Chemical class 0.000 claims 4
- 125000006732 (C1-C15) alkyl group Chemical group 0.000 claims 2
- 125000004104 aryloxy group Chemical group 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 125000001475 halogen functional group Chemical group 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 125000001424 substituent group Chemical group 0.000 claims 2
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- 125000005108 alkenylthio group Chemical group 0.000 claims 1
- 125000003282 alkyl amino group Chemical group 0.000 claims 1
- 125000004414 alkyl thio group Chemical group 0.000 claims 1
- -1 amino, thio, sulfinyl Chemical group 0.000 claims 1
- 150000001540 azides Chemical class 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 125000001145 hydrido group Chemical group *[H] 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 125000004076 pyridyl group Chemical group 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 claims 1
- 125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17094399P | 1999-12-15 | 1999-12-15 | |
| US60/170,943 | 1999-12-15 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001544761A Division JP4990456B2 (ja) | 1999-12-15 | 2000-12-15 | 抗菌剤としてのダプトマイシンアナログ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012140432A JP2012140432A (ja) | 2012-07-26 |
| JP2012140432A5 true JP2012140432A5 (en:Method) | 2013-04-11 |
Family
ID=22621910
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001544761A Expired - Fee Related JP4990456B2 (ja) | 1999-12-15 | 2000-12-15 | 抗菌剤としてのダプトマイシンアナログ |
| JP2012015294A Pending JP2012140432A (ja) | 1999-12-15 | 2012-01-27 | 抗菌剤としてのダプトマイシンアナログ |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001544761A Expired - Fee Related JP4990456B2 (ja) | 1999-12-15 | 2000-12-15 | 抗菌剤としてのダプトマイシンアナログ |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6911525B2 (en:Method) |
| EP (4) | EP1240181A2 (en:Method) |
| JP (2) | JP4990456B2 (en:Method) |
| KR (1) | KR20020063227A (en:Method) |
| CN (1) | CN1425025A (en:Method) |
| AU (1) | AU784755B2 (en:Method) |
| BR (1) | BR0017026A (en:Method) |
| CA (1) | CA2393907A1 (en:Method) |
| IL (2) | IL150223A0 (en:Method) |
| MX (1) | MXPA02006029A (en:Method) |
| NO (1) | NO20022888L (en:Method) |
| WO (1) | WO2001044272A2 (en:Method) |
| ZA (1) | ZA200205106B (en:Method) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA02006030A (es) * | 1999-12-15 | 2004-08-23 | Cubist Pharm Inc | Lipopeptidos como agentes antibacterianos. |
| US6696412B1 (en) | 2000-01-20 | 2004-02-24 | Cubist Pharmaceuticals, Inc. | High purity lipopeptides, Lipopeptide micelles and processes for preparing same |
| CA2301336A1 (en) * | 2000-03-17 | 2001-09-17 | Michael T. Kelly | Topical treatment of rosacea |
| NZ571597A (en) | 2000-12-18 | 2010-05-28 | Cubist Pharm Inc | Method for preparing crystalline and crystal-like forms of purified daptomycin lipopeptides |
| US20060014674A1 (en) | 2000-12-18 | 2006-01-19 | Dennis Keith | Methods for preparing purified lipopeptides |
| ATE430160T1 (de) * | 2001-08-06 | 2009-05-15 | Cubist Pharm Inc | Lipopeptid-stereoisomere, verfahren zu ihrer herstellung und nützliche zwischenprodukte |
| EP1932853A1 (en) | 2001-08-06 | 2008-06-18 | Cubist Pharmaceutical Inc. | Novel depsipeptides and process for preparing same |
| CA2458644A1 (en) * | 2001-08-28 | 2003-03-13 | Pharmacia Corporation | Crystaline clindamycin free base |
| US6767718B2 (en) | 2002-05-10 | 2004-07-27 | Biosource Pharm, Inc. | Lipodepsipeptide antibiotics and methods of preparation |
| WO2003099217A2 (en) * | 2002-05-23 | 2003-12-04 | Activbiotics, Inc. | Methods of treating bacterial infections and diseases associated therewith |
| AU2003240545A1 (en) | 2002-06-06 | 2003-12-22 | Therapeutics Corporation Genome | Use of ramoplanin to treat diseases associated with the use of antibiotics |
| IL150907A (en) * | 2002-07-25 | 2007-07-04 | Stephan Cherkez | Process for the preparation of stable amorphous calcium pseudomonate |
| ITMI20022076A1 (it) * | 2002-10-01 | 2004-04-02 | Antibioticos Spa | Sali di intermedi del cefdinir. |
| US20040132764A1 (en) * | 2002-10-23 | 2004-07-08 | Morphochem Aktiengesellschaft Fuer Kombinatorische Chemie | Antibiotics for the treatment of infections in acidic environments |
| US20060004185A1 (en) | 2004-07-01 | 2006-01-05 | Leese Richard A | Peptide antibiotics and peptide intermediates for their prepartion |
| US20080051326A1 (en) * | 2004-11-12 | 2008-02-28 | Alexander Dylan C | Antiinfective Lipopeptides |
| JP2008519848A (ja) * | 2004-11-12 | 2008-06-12 | キュービスト ファーマシューティカルズ， インコーポレイテッド | 抗感染性リポペプチド |
| NZ580951A (en) * | 2005-04-29 | 2011-06-30 | Cubist Pharm Inc | Therapeutic compositions |
| WO2007127218A2 (en) * | 2006-04-26 | 2007-11-08 | Taro Pharmaceuticals U.S.A., Inc. | Streptomyces-derived antimicrobial compound and method of using same against antibiotic-resistant bacteria |
| EP2054044B1 (de) * | 2006-08-02 | 2014-07-23 | Johannes Gutenberg-Universität Mainz | Arzneimittel gegen lct-vergiftungen |
| US8662086B2 (en) | 2007-02-06 | 2014-03-04 | BBK Tobacco & Foods, LLP | Reclosable package with magnetic clasp for rolling papers used in smoking articles |
| US8584854B2 (en) * | 2007-02-06 | 2013-11-19 | BBK Tobacco & Foods, LLP | Reclosable package with magnetic clasp and detachable tray for rolling papers used in smoking articles |
| US20080185010A1 (en) * | 2007-02-06 | 2008-08-07 | Kesselman Joshua D | Interleaved Transparent Cellulose Paper with Opaque Adhesive |
| US20090020443A1 (en) * | 2007-05-09 | 2009-01-22 | Kesselman Joshua D | Credit Card Carrying Pack for Rolling Papers |
| US9161572B2 (en) * | 2007-06-15 | 2015-10-20 | Bbk Tobacco & Foods, Inc. | Structures for creating smoking articles and methods of packaging same |
| US9072319B2 (en) | 2007-06-15 | 2015-07-07 | Joshua D. Kesselman | Rolling paper structures for creating smoking articles and gummed, coiled inserts for same |
| US20090014342A1 (en) * | 2007-07-14 | 2009-01-15 | Kesselman Joshua D | Rolling papers and methods of packaging same |
| EP2018864A1 (en) | 2007-07-23 | 2009-01-28 | Biomet Deutschland GmbH | Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition |
| AU2008343502A1 (en) * | 2007-12-26 | 2009-07-09 | Biomarin Pharmaceutical Inc. | Novel semi-synthetic glycopeptides as antibacterial agents |
| US8393332B2 (en) | 2008-08-21 | 2013-03-12 | BBK Tobacco & Foods, LLP | Packaging for rolling papers for smoking articles |
| USD606858S1 (en) | 2008-08-21 | 2009-12-29 | Joshua Kesselman | Packaging for smoking articles |
| GB2465863A (en) * | 2008-12-05 | 2010-06-09 | Lead Therapeutics Inc | Semi-synthetic heptapeptidic glycopeptides for the treatment of bacterial infections |
| NZ594019A (en) * | 2008-12-22 | 2013-08-30 | Cubist Pharm Inc | Novel antibacterial agents for the treatment of gram positive infections |
| TW201035111A (en) | 2008-12-23 | 2010-10-01 | Biosource Pharm Inc | Antibiotic compositions for the treatment of gram negative infections |
| ES2374779B1 (es) * | 2010-03-10 | 2012-12-27 | Universidad De Barcelona | Compuestos péptidicos útiles como agentes antibacterianos. |
| US8415307B1 (en) | 2010-06-23 | 2013-04-09 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| WO2012011917A1 (en) * | 2010-07-23 | 2012-01-26 | Activbiotics Pharma, Llc | Administration of rifalazil to immunocompromised patients |
| US10072045B1 (en) | 2017-06-26 | 2018-09-11 | Ramapo Pharmaceuticals, Inc. | Antibacterial lipopeptides and methods for their preparation and use |
| US10526343B2 (en) | 2018-03-26 | 2020-01-07 | University Of Sharjah | Heterocyclic systems and pharmaceutical applications thereof |
| CN110577581A (zh) * | 2018-06-07 | 2019-12-17 | 美国蓝博药业公司 | 一种新型的抑菌脂肽化合物、制备方法及其应用 |
| CN109182563B (zh) * | 2018-08-01 | 2020-07-14 | 浙江大学 | 检测20种dfrA类甲氧苄胺嘧啶类药物耐药基因的方法及所用试剂盒 |
| CN113061164B (zh) * | 2021-03-29 | 2023-01-10 | 四川大学 | 环脂肽类化合物及其在抗类风湿关节炎药物中的应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3854480A (en) | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
| USRE32333E (en) | 1978-10-16 | 1987-01-20 | Eli Lilly And Company | A-21978 Antibiotics and process for their production |
| USRE32455E (en) | 1978-10-16 | 1987-07-07 | Eli Lilly And Company | A-21978 antibiotics and process for their production |
| ES8403890A1 (es) | 1982-02-27 | 1984-04-01 | Beecham Group Plc | Un procedimiento para la preparacion de derivados de 1-normon-2-ilo. |
| USRE32311E (en) | 1982-05-21 | 1986-12-16 | Eli Lilly And Company | Derivatives of A-21978C cyclic peptides |
| US4396543A (en) * | 1982-05-21 | 1983-08-02 | Eli Lilly And Company | Derivatives of A-21978C cyclic peptides |
| US4537717A (en) | 1982-05-21 | 1985-08-27 | Eli Lilly And Company | Derivatives of A-21978C cyclic peptides |
| US4399067A (en) * | 1982-05-21 | 1983-08-16 | Eli Lilly And Company | Derivatives of A-21978C cyclic peptides |
| IL68700A0 (en) * | 1982-05-21 | 1983-09-30 | Lilly Co Eli | Improvements relating to a-21978c cyclic peptide derivatives and their production |
| US4482487A (en) * | 1982-05-21 | 1984-11-13 | Eli Lilly And Company | A-21978C cyclic peptides |
| US4524135A (en) * | 1982-05-21 | 1985-06-18 | Eli Lilly And Company | A-21978C cyclic peptides |
| USRE32310E (en) | 1982-05-21 | 1986-12-16 | Eli Lilly And Company | Derivatives of A-21978C cyclic peptides |
| US4452775A (en) | 1982-12-03 | 1984-06-05 | Syntex (U.S.A.) Inc. | Cholesterol matrix delivery system for sustained release of macromolecules |
| KR890000800B1 (ko) | 1984-10-09 | 1989-04-07 | 일라이 릴리 앤드 캄파니 | A-21978c 유도체의 제조방법 |
| US4885243A (en) | 1984-10-09 | 1989-12-05 | Eli Lilly And Company | Process for producing A-21978C derivatives |
| US4874843A (en) | 1987-12-03 | 1989-10-17 | Eli Lilly And Company | Chromatographic purification process |
| CA1315229C (en) | 1987-06-10 | 1993-03-30 | Patrick J. Baker | Chromatographic purification process |
| CA2043762C (en) * | 1990-06-07 | 2001-05-29 | Adam J. Kreuzman | Lipopeptide deacylase |
| JPH04167172A (ja) | 1990-10-31 | 1992-06-15 | Nec Corp | ベクトルプロセッサ |
| EP0712405A1 (en) | 1993-08-13 | 1996-05-22 | Smithkline Beecham Plc | Derivatives of monic acids a and c having antibacterial, antimycoplasmatical, antifungal and herbicidal activity |
| DE4411025A1 (de) | 1994-03-30 | 1995-10-05 | Hoechst Ag | Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung |
| WO1997032975A1 (en) | 1996-03-08 | 1997-09-12 | Fujisawa Pharmaceutical Co., Ltd. | Process for the deacylation of cyclic lipopeptides |
| DE19807972A1 (de) | 1998-02-25 | 1999-08-26 | Hoechst Marion Roussel De Gmbh | Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung |
| ES2259845T3 (es) | 1998-09-25 | 2006-10-16 | Cubist Pharmaceuticals, Inc. | Uso de la daptomicina. |
| US9393093B2 (en) | 2008-02-18 | 2016-07-19 | Covidien Lp | Clip for implant deployment device |
-
2000
- 2000-12-15 US US09/738,742 patent/US6911525B2/en not_active Expired - Lifetime
- 2000-12-15 CN CN00818471A patent/CN1425025A/zh active Pending
- 2000-12-15 IL IL15022300A patent/IL150223A0/xx unknown
- 2000-12-15 JP JP2001544761A patent/JP4990456B2/ja not_active Expired - Fee Related
- 2000-12-15 EP EP00986444A patent/EP1240181A2/en not_active Withdrawn
- 2000-12-15 MX MXPA02006029A patent/MXPA02006029A/es unknown
- 2000-12-15 EP EP10182938A patent/EP2295444A3/en not_active Withdrawn
- 2000-12-15 EP EP07022686A patent/EP1884520A3/en not_active Withdrawn
- 2000-12-15 WO PCT/US2000/034118 patent/WO2001044272A2/en not_active Ceased
- 2000-12-15 CA CA002393907A patent/CA2393907A1/en not_active Abandoned
- 2000-12-15 AU AU22682/01A patent/AU784755B2/en not_active Ceased
- 2000-12-15 EP EP10182947A patent/EP2298790A1/en not_active Withdrawn
- 2000-12-15 BR BR0017026-7A patent/BR0017026A/pt not_active Application Discontinuation
- 2000-12-15 KR KR1020027007665A patent/KR20020063227A/ko not_active Withdrawn
-
2002
- 2002-06-13 IL IL150223A patent/IL150223A/en not_active IP Right Cessation
- 2002-06-17 NO NO20022888A patent/NO20022888L/no not_active Application Discontinuation
- 2002-06-25 ZA ZA200205106A patent/ZA200205106B/xx unknown
-
2005
- 2005-05-04 US US11/121,851 patent/US7335725B2/en not_active Expired - Fee Related
-
2012
- 2012-01-27 JP JP2012015294A patent/JP2012140432A/ja active Pending
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