JP2012078115A - Inspection object acceptor - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an inspection object acceptor which can prevent unintentional outflow of a liquid due to a capillary phenomenon in a flow channel.SOLUTION: In a plate-like member 2 of an inspection object acceptor 1, there are formed: a first liquid sump portion 5 including a recessed portion having a predetermined depth; a measurement portion 4 which measures, by a predetermined amount, a liquid that is an inspection object and outflows from the first liquid sump portion 5; and a first flow channel 7 through which the liquid flows from the first liquid sump portion 5 toward the measurement portion 4. In the plate-like member 2, there are provided a receiving portion 17 into which the liquid measured by the measurement portion 4 flows, a second flow channel 20 through which the liquid flows from the measurement portion 4 to the receiving portion 17, a third flow channel 30 through which a remainder of the liquid outflowing from the first liquid sump portion 5 via the first flow channel 7 and measured by the measurement portion 4 flows, and a surplus portion 10 which is provided at an end of the third flow channel 30. In the second flow channel 20, a cross section enlarged portion 24 is provided. In the third flow channel 30, a cross section enlarged portion 34 is provided.

Description

  The present invention relates to a test target receptor, for example, a test target receiver for performing chemical, medical, and biological tests.

  Conventionally, in the field of chemical, medical, and biological examinations, when detecting and quantifying DNA (Deoxyribo Nucleic Acid), enzymes, antigens, antibodies, proteins, viruses, cells and other biological materials, and chemical substances An inspection object receiver called a microchip or an inspection chip used for the above has been proposed. In this inspection object receptacle, the liquid to be inspected is injected into the internal liquid supply path, the inspection object receiver is held horizontally and revolved, and the centrifugal force generated by the revolution is used to inspect the inspection object. The inspection is performed by moving the liquid to a plurality of mixing tanks in the flow path formed in the receiver (for example, see Patent Document 1). In this inspection object receiver, a predetermined amount of liquid is measured in the sample measuring chamber (corresponding to the “metering unit” of the present application), and the remaining liquid flows into the overflow chamber (corresponding to the “extra part” of the present application). It has become. Further, the liquid measured in the sample measuring chamber flows into the cuppet chamber (corresponding to the “receiving portion” in the present application) and is mixed with other liquids and reagents.

JP 60-238760 A

  Since the test object receiver in which the fluid circuit is formed uses a very small amount of liquid as is called microtus (μ-TAS), the flow path is very thin. When the liquid is allowed to flow from the liquid reservoir to the measuring part, if the direction of the test target receptacle is changed while the centrifugal force is applied, the liquid may flow out to an unintended flow path. In this case, since the flow path is very thin, there is a problem that the liquid flows to the tip of the flow path due to capillary action. In addition, when a centrifugal force is applied in the direction in which the liquid flows from the liquid reservoir to the measuring unit, and the liquid flows from the liquid reservoir to the measuring unit, the liquid flowing out from the flow path of the liquid reservoir flows to the measuring unit. Without. There is a problem in that it flows into the flow path to the receiving part mixed with the reagent by capillary action. In this case, there was a problem that accurate measurement could not be performed.

  The present invention has been made to solve the above-described problems, and an object of the present invention is to realize an inspection target receptacle that can prevent unintentional outflow of liquid due to capillary action in a flow path.

  In order to achieve the above object, in the inspection target receptacle according to the first aspect of the present invention, the rotational direction of the centrifugal force generated by the revolution is sequentially held at a plurality of predetermined rotation angles by rotation, and the inspection target An inspection object receiver used for an application for inspecting by moving a liquid inside, the inspection object receiver is composed of a plate member having a predetermined thickness and a cover member covering the surface of the plate member, On the surface of the plate member, at least a liquid reservoir that stores a liquid to be inspected, a first channel that is connected to the liquid reservoir and flows out of the liquid reservoir, and the liquid in the first channel Opposed to the end opposite to the reservoir side, the metering unit that weighs a predetermined amount of the liquid, the receiving unit into which the liquid weighed by the metering unit flows, and the metering unit was weighed A second flow path for flowing liquid to the receiving portion, and the second flow path , Toward the receiving portion from the metering portion, the cross-sectional area of the flow path, characterized in that the cross-sectional area enlarged portion has expanded continuously is provided.

  In the test object receiver having this configuration, when the liquid is allowed to flow from the liquid reservoir to the measuring part, the second flow path to the receiver is provided with a cross-sectional area enlarged portion. Unintentional outflow of liquid into the road can be prevented.

  In addition, the cross-sectional area enlarged portion of the second flow path is continuously expanded by increasing the depth of the flow path in the thickness direction of the plate member continuously. May be. In this case, by increasing the depth of the flow path continuously, the cross-sectional area enlarged portion can be formed without increasing the area of the test object receptacle.

  The cross-sectional area enlarged portion of the second flow path may start from an end portion on the receiving portion side of the opening portion of the measuring portion. In this case, unintentional outflow of liquid due to capillary action from the end of the opening of the measuring portion to the second flow path can be prevented. Therefore, it is possible to smoothly flow the liquid to the measuring unit.

  In addition, an inflection point with respect to the upstream direction of the centrifugal force is provided in the middle of the second flow path in a state where a centrifugal force is applied so that the liquid flows from the liquid reservoir to the measuring unit. May be. In this case, even when an unintended liquid flows in the second flow path, it can be prevented from flowing from the inflection point first.

  The inspection object receiver further includes a surplus part for storing the liquid overflowing from the measuring part, and a third flow path for flowing the liquid overflowing from the measuring part to the surplus part, and the third flow path. May have a cross-sectional area enlarged portion in which the cross-sectional area of the flow path continuously increases from the measuring portion side toward the surplus portion. In this case, it is possible to prevent an unintended liquid from flowing into the third flow path due to capillary action.

  In addition, the cross-sectional area enlarged portion of the third flow path has the cross-sectional area of the flow path continuously expanded by continuously increasing the depth of the flow path in the thickness direction of the plate member. May be. By increasing the depth of the flow path continuously, the cross-sectional area enlarged portion can be formed without increasing the area of the test subject receptacle.

  Further, the cross-sectional area enlarged portion of the third flow path may start from an end portion on the surplus portion side of the opening portion of the measuring portion. In this case, in this case, it is possible to prevent unintentional outflow of the liquid from the end of the opening of the measuring unit to the third channel due to the capillary phenomenon of the third channel. Therefore, it is possible to smoothly flow the liquid to the measuring unit.

3 is a plan view of the inspection device 50. FIG. It is a front view of the test object receiver. It is a bending sectional view of the direction of an arrow in the XX line of Drawing 2 of inspection subject receptacle 1 of a first embodiment. It is a bending sectional view of the direction of an arrow in the XX line of Drawing 2 of inspection subject receptacle 1 of a second embodiment. It is a bending sectional view of the direction of an arrow in the XX line of Drawing 2 of inspection subject receptacle 1 of a third embodiment. It is a bending sectional view of the direction of an arrow in the XX line of Drawing 2 of inspection subject receptacle 1 of a fourth embodiment. It is a front view of the test object receptacle 1 of 5th embodiment. It is a front view of the test subject receptacle 1 in the state which injected the liquid. It is a front view of the state which rotated the to-be-inspected receiving body 1 90 degree counterclockwise. It is a front view of the state which gave the centrifugal force to the test object receiver 1 and poured the liquid into the measurement part. FIG. 6 is a front view of a state in which a liquid is poured from the measuring unit 4 of the inspection receiver 1 into the receiving unit 17. It is a front view of the state which stopped revolution of inspection object receptacle.

  Hereinafter, a first embodiment of the present invention will be described. In the present embodiment, the inspection target receptacle 1 is mounted on the inspection apparatus 50 shown in FIG. 1 so that the bottom surface of the inspection target receptacle 1 is mounted in parallel with the direction of gravity (the paper surface direction in FIG. 1) and revolved and centrifuged. Power is added. First, the structure of the inspection apparatus 50 will be briefly described with reference to FIG. As shown in FIG. 1, a rotating disk-shaped turntable 53 is provided on the upper plate 52 of the inspection apparatus 50. A holder angle changing mechanism 54 is provided on the turntable 53. The holder angle changing mechanism 54 is provided with a pair of holders 57 that are inserted and fixed to the inspection object receiver 1 and rotate by a predetermined angle. A motor (not shown) is provided below the upper plate 52 so as to drive the turntable 53 in rotation. Centrifugal force acts in the direction of arrow A on the test subject receivers 1 inserted into the holders 57 by the turntable 53 rotating about its central portion 55 as an axis. Further, the holder 57 is rotated by the operation of the holder angle changing mechanism 54 so that the direction of the centrifugal force acting on the test subject receptacle 1 can be changed.

  Next, the structure of the inspection object receiver 1 will be described with reference to FIGS. FIG. 2 is a front view when the inspection object receiver 1 is mounted on the inspection apparatus 50, and the front and back surfaces of the inspection object receiver 1 are parallel to the direction of gravity (downward in FIG. 2). . As shown in FIG.2 and FIG.3, the test object receptacle 1 is comprised from the board member 2 which has a predetermined | prescribed thickness with a rectangle in front view. As an example of the material of the plate member 2, a synthetic resin can be used. A cover member 3 that covers the surface of the inspection object receiver 1 is attached to the inspection object receiver 1 on the surface side (upper side in FIG. 3). The cover member 3 includes a first liquid reservoir 5, a second liquid reservoir 6, a first flow path 7, a second flow path 20, a third flow path 30, a fourth flow path 8, a metering section 4, and a surplus section, which will be described later. 10 and the receiving part 17 are sealed.

  As shown in FIGS. 2 and 3, the cover member 3 is composed of a transparent thin plate of a rectangular synthetic resin having the same shape as the plate member 2 in front view. Further, the cover member 3 is formed with an inlet 15 for injecting a liquid to be inspected into the first liquid reservoir 5 and an inlet 16 for injecting a reagent or the like mixed with the liquid to be inspected into the second liquid reservoir 6. Has been.

  As shown in FIG. 2, the plate member 2 of the test object receptacle 1 has a first liquid reservoir portion 5 formed of a concave portion dug down to a predetermined depth in the thickness direction of the plate, and flows out of the first liquid reservoir portion 5. A metering unit 4 that takes a predetermined amount of the liquid to be inspected and a first flow path 7 through which the liquid flows from the first liquid reservoir 5 toward the metering unit 4 are provided. Further, the plate member 2 includes a receiving portion 17 into which the liquid measured by the measuring portion 4 flows, a second flow path 20 for flowing the liquid from the measuring portion 4 to the receiving portion 17, and a first flow path from the first liquid reservoir portion 5. 7 and the third flow path 30 through which the remaining liquid weighed by the measuring section 4 flows, and the surplus section 10 provided at the end of the third flow path 30 where the remaining liquid weighed by the measuring section 4 accumulates. Is provided. The plate member 2 has a second liquid reservoir 6 formed of a recess dug down to a predetermined depth in the thickness direction of the plate, and a fourth flow for flowing a liquid such as a reagent from the second liquid reservoir 6 to the receiving portion 17. A path 8 is provided.

  The first liquid reservoir 5 is a portion that accumulates the liquid to be inspected injected from the injection port 15 and is dug down to a predetermined depth with respect to the plate member 2 in a pentagonal view in front view. Further, the second liquid reservoir 6 is a portion that accumulates the reagent and the like injected from the injection port 16 and is dug down to the plate member 2 by a predetermined depth in a pentagonal view in front view. As shown in FIG. 2, the measuring unit 4 is provided on the opposing surface of the outlet of the first flow path 7 from the first liquid reservoir 5 in the liquid outflow direction. The measuring unit 4 is also dug down by a predetermined depth with respect to the plate member 2 and extends in a diagonal direction by a predetermined length. Further, as shown in FIG. 2, a receiving portion 17 is provided on the opposing surface of the outlet in the liquid outflow direction of the fourth flow path 8 from the second liquid reservoir 6.

  Further, an excess portion 10 is formed at the downstream end of the third flow path 30 by being dug down by a predetermined depth in the thickness direction of the plate member 2. The surplus portion 10 flows out and accumulates the remaining liquid that has flowed out of the first liquid reservoir 5 and measured by the metering portion 4 by a predetermined amount. A receiving portion 17 is formed at the downstream end of the second flow path 20. The receiving portion 17 is dug down to a predetermined depth in the thickness direction of the plate member 2, and the liquid taken out by the predetermined amount by the measuring portion 4 flows in and mixes with the reagent and the like flowing in from the second liquid reservoir portion 6. Is done.

  Next, the structure of the second flow path 20 will be described. As shown in FIG. 2, the second flow path 20 is a groove that is dug down by a predetermined depth with respect to the thickness direction of the plate member 2 and has a rectangular cross section perpendicular to the extending direction of the second flow path 20. The second flow path 20 is a flow path bent in the direction of the receiving portion 17 by the bent portion 22, and the width of the second flow path 20 in the direction orthogonal to the extending direction of the second flow path 20 is the measuring section. 4 from the end 41 on the receiving portion 17 side of the opening 4 to the inflection point 21 is continuously enlarged. Further, as shown in FIG. 3, the depth of the second flow path 20 (in the thickness direction of the plate member 2) from the end portion 41 on the receiving portion 17 side of the opening of the measuring portion 4 to the inflection point 21. ) Is continuously deeper toward the receiving portion 17 side. Therefore, from the end portion 41 on the receiving portion 17 side of the opening of the measuring portion 4 to the inflection point 21, a cross-sectional area enlarged portion 24 where the cross-sectional area of the second flow path 20 continuously increases is obtained.

  Further, as shown in FIG. 2, between the inflection point 21 of the second flow path 20 and the receiving portion 17, a bent portion 22 where the second flow path 20 is bent in a hairpin shape is provided. As shown in FIG. 10, the inflection point 21 is in the upstream direction of the centrifugal force in the second flow path 20 (see FIG. 10) in a state where a centrifugal force is applied so that the liquid flows from the first liquid reservoir 5 to the measuring unit 4. 10 is the inflection point in the direction opposite to arrow A). Since the second flow path 20 is bent with respect to the upstream direction of the centrifugal force due to the inflection point 21, it leaks into the second flow path 20 when the liquid flows from the first liquid reservoir 5 to the measuring unit 4. The liquid can be prevented from flowing into the receiving part 17.

  Next, the structure of the third flow path 30 will be described with reference to FIGS. 2 and 3. As shown in FIG. 2, the third flow path 30 is dug down by a predetermined depth with respect to the thickness direction of the plate member 2, and the extending direction of the third flow path 30 (downwardly diagonally downward in FIG. 2). The cross section orthogonal to is a rectangular groove. The width of the third flow path 30 in the direction orthogonal to the extending direction of the third flow path 30 is continuous in the enlarged portion 31 whose width is once increased from the end portion 42 on the surplus portion 10 side of the opening of the measuring portion 4. Is expanding. Further, as shown in FIG. 3, the depth of the third flow path 30 (plate member) from the end 42 on the surplus portion 10 side of the opening of the measuring section 4 to the inflection point 35 at which the third flow path 30 bends. 2 in the thickness direction of 2) is continuously deeper toward the surplus portion 10 side. Therefore, from the end part 42 on the surplus part 10 side of the opening part of the measuring part 4 to the inflection point 35 is a cross-sectional area enlarged portion 34 where the cross-sectional area of the third flow path 30 continuously increases.

  In the test object receiver 1 of the first embodiment, the cross-sectional area is enlarged from the end 41 on the receiving portion 17 side of the opening of the measuring portion 4 to the second flow path 20 through which the liquid flows from the measuring portion 4 to the receiving portion 17. Since the portion 24 is formed to have a predetermined length, it is possible to prevent unintentional outflow of liquid into the second flow path due to capillary action even in a thin flow path. Similarly, the cross-sectional area enlarged portion 34 also has a predetermined length from the end portion 42 on the surplus portion 10 side of the opening of the measuring portion 4 in the third flow path 30 for flowing the liquid overflowing from the measuring portion 4 to the surplus portion 10. Since it is formed, it is possible to prevent unintentional outflow of liquid into the third channel due to capillary action even in a narrow channel.

  Next, with reference to FIG.2 and FIG.4, the test object receptacle 1 of 2nd embodiment is demonstrated. In the inspection target receptacle 1 of the second embodiment, when the inspection target receptacle 1 is viewed from the front, the shapes of the second flow path 20 and the third flow path 30 look the same as in the first embodiment. As shown in FIG. 4, the second flow path 20 and the third flow path 30 have a constant flow path depth. However, since the width of the flow path of the second flow path 20 is continuously increased up to the inflection point 21, the cross-sectional area of the flow path is continuously increased. In addition, since the third flow path 30 also has the enlarged portion 31, there is a portion where the width of the flow path is continuously widened, so that the cross-sectional area of the flow path is continuously expanded. Also in the test target receptacle 1 of the second embodiment, the cross-sectional area of the flow channel is continuously enlarged, so that the liquid flow unintended due to capillary action on the second flow channel 20 and the third flow channel 30 is not achieved. Inflow can be prevented.

  Next, with reference to FIG.2 and FIG.5, the test object receptacle 1 of 3rd embodiment is demonstrated. In the inspection target receptacle 1 of the third embodiment, when the inspection target receptacle 1 is viewed from the front, the shapes of the second flow path 20 and the third flow path 30 look the same as in the first embodiment. As shown in FIG. 5, the depth of the third flow path 30 is constant, but the second flow path 20 extends from the end 41 on the receiving portion 17 side of the opening of the measuring unit 4 to the inflection point 21. The depth of the channel is continuously increased toward the receiving portion 17 side. Therefore, from the end portion 41 on the receiving portion 17 side of the opening of the measuring portion 4 to the inflection point 21, a cross-sectional area enlarged portion 24 where the cross-sectional area of the second flow path 20 continuously increases is obtained. In addition, since the third flow path 30 also has the enlarged portion 31, there is a portion where the width of the flow path is continuously widened, so that the cross-sectional area of the flow path is continuously expanded. Also in the test subject receptacle 1 of the third embodiment, the cross-sectional area of the flow path is continuously enlarged, so that unintended liquid flows into the second flow path 20 and the third flow path 30 due to capillary action. Can be prevented.

  Next, with reference to FIG.2 and FIG.6, the test object receptacle 1 of 4th embodiment is demonstrated. In the inspection target receptacle 1 of the fourth embodiment, when the inspection target receptacle 1 is viewed from the front, the shapes of the second flow path 20 and the third flow path 30 look the same as in the first embodiment. As shown in FIG. 6, the depth of the second flow path 20 is constant, but the third flow path 30 extends from the end 42 on the surplus portion 10 side of the opening of the measuring portion 4 to the inflection point 35. The depth of the flow path is continuously increased. Therefore, the cross-sectional area enlarged portion 34 where the cross-sectional area of the third flow path 30 continuously increases. Further, in the second flow path 20, since there is a portion where the width of the flow path is continuously widened, the cross-sectional area of the flow path is continuously expanded. Also in the test target receptacle 1 of the fourth embodiment, the cross-sectional area of the flow path is continuously enlarged, so that unintended liquid flows into the second flow path 20 and the third flow path 30 due to capillary action. Can be prevented.

  Next, with reference to FIG.3 and FIG.7, the test object receptacle 1 of 5th embodiment is demonstrated. As shown in FIG. 7, in the inspection object receiver 1 of the fifth embodiment, when the inspection object receiver 1 is viewed from the front, the second flow path 20 and the third flow path 30 have the width of the flow path. There is no continuous expansion. However, as shown in FIG. 3, the second flow path 20 has a cross-sectional area enlarged portion 24 where the flow path depth continuously increases, and similarly, the third flow path 30 has a continuous flow path depth. There is a cross-sectional area enlarged portion 34 that becomes deeper. Accordingly, also in the test object receptacle 1 of the fifth embodiment, the cross-sectional area of the flow channel is continuously enlarged, so that an unintended liquid due to capillary action on the second flow channel 20 and the third flow channel 30 is obtained. Can be prevented.

  Next, with reference to FIG. 8 to FIG. 12, a method for using the inspection target receptacle 1 of the first embodiment will be described. As shown in FIG. 8, in the test target receptacle 1, the liquid to be tested is injected from the injection port 15 into the first liquid reservoir 5, and the reagent is injected from the injection port 16 into the second liquid reservoir 6. The injected liquid accumulates in the first liquid reservoir 5 and the second liquid reservoir 6. Next, the inspection object receiver 1 is fixed to the holder 57 of the turntable 53 of the inspection apparatus 50 shown in FIG. And the holder 57 of the test | inspection apparatus 50 rotates, and the test object receiver 1 is rotated to the state shown in FIG. Next, as shown in FIG. 10, the inspection object receiver 1 revolves around a rotation axis parallel to the gravity direction (arrow B direction), and centrifugal force is applied to the inspection object receiver 1 in the arrow A direction. . At this time, as shown in FIG. 10, the liquid accumulated in the first liquid reservoir 5 flows out and is measured by the measuring unit 4 by a predetermined amount. At this time, the second flow path 20 is provided with the cross-sectional area enlarged portion 24, and the third flow path 30 is provided with the cross-sectional area enlarged portion 34. Therefore, it is possible to prevent an unintended flow of the liquid due to the capillary phenomenon with respect to 30 and to smoothly flow the liquid to the measuring unit 4. Here, the excess liquid overflowing from the measuring unit 4 flows through the third flow path 30 by the applied centrifugal force and accumulates in the excess unit 10. Further, the liquid that has flowed into the surplus portion 10 is attracted to the back of the surplus portion 10 by centrifugal force (in the direction of arrow A in FIG. 10). Further, the reagent accumulated in the second liquid reservoir 6 flows into the receiver 17.

  Next, as shown in FIG. 11, the test object receiver 1 is rotated 90 degrees clockwise and is given a centrifugal force due to revolution (in the direction of arrow A in FIG. 11). As shown in FIG. 11, the liquid accumulated in the measuring unit 4 flows through the second flow path 20 by the applied centrifugal force and flows into the receiving unit 17, and is received from the second liquid storing unit 6 first. It is mixed with the reagent flowing into the part 17. Thereafter, when the rotation of the turntable 53 of the inspection apparatus 50 stops, as shown in FIG. 12, the excess liquid of the liquid to be inspected is accumulated in the back part 13 of the excess part 10, and the liquid mixed with the reagent is received by the receiving part. Accumulate at 17. After that, the measurement is performed by a method such as an optical method in which light is applied to the liquid mixed in the receiving portion 17 for examination.

  As described above, in the test object receiver 1 of the above embodiment, the cross-sectional area enlarged portion 24 is provided in the second flow path 20, and the cross-sectional area enlarged portion 34 is provided in the third flow path 30. 4, the unintentional flow of liquid due to capillary action into the second flow path 20 and the third flow path 30 is prevented, and the liquid is smoothly supplied from the first flow path 7 of the first liquid reservoir 5 to the measurement section 4. It can flow. In addition, an inflection point 21 with respect to the upstream direction of the centrifugal force is provided in the second flow path 20 with a centrifugal force applied so that the liquid flows from the first liquid reservoir 5 to the measuring unit 4. Even if excess liquid overflowing from the measuring unit 4 flows into the second flow path 20, it can be prevented from flowing into the receiving unit 17.

  The present invention is not limited to the above embodiment, and various modifications can be made. For example, the cross-sectional area enlarged portion 24 of the second flow path 20 may be formed not to the inflection point 21 but to the bending portion 22. The cross-sectional area enlarged portion 34 of the third flow path 30 may also be formed up to the surplus portion 10 ahead of the inflection point 35.

  Further, for example, the material of the test object receiver 1 is not particularly limited, and polyethylene terephthalate (PET), polybutylene terephthalate (PBT), polymethyl methacrylate (PMMA), polycarbonate (PC), polystyrene (PS), polypropylene (PP) ), Polyethylene (PE), polyethylene naphthalate (PEN), polyarylate resin (PAR), acrylonitrile-butadiene-styrene resin (ABS), vinyl chloride resin (PVC), polymethylpentene resin (PMP), polybutadiene resin (PBD) ), Biodegradable polymer (BP), cycloolefin polymer (COP), polydimethylsiloxane (PDMS), and other organic materials can be used. In addition, an inorganic material such as silicon, glass, or quartz may be used. In addition, in the inspection object receiver 1, two liquid inlets are provided, but one, three, four, etc. may be provided as appropriate.

DESCRIPTION OF SYMBOLS 1 Inspection object receptacle 2 Plate member 3 Cover member 4 Measuring part 5 1st liquid reservoir part 6 2nd liquid reservoir part 10 Surplus part 11 Flow path 13 Reservoir part 15 Inlet 16 Inlet 17 Receiving part 20 Second flow path 21 Inflection point 22 Bent part 24 Cross-sectional area enlarged part 30 Third flow path 31 Enlarged part 34 Cross-sectional area enlarged part 35 Inflection point 41 End part 42 End part

Claims (7)

A test object receiver that is sequentially held at a plurality of predetermined rotation angles by rotation with respect to the direction of centrifugal force generated by revolution, and that is used for inspection by moving a liquid to be inspected inside,
The inspection object receiver is composed of a plate member having a predetermined thickness and a cover member covering the surface of the plate member,
On the surface of the plate member, at least,
A liquid reservoir for storing the liquid to be inspected;
A first flow path connected to the liquid reservoir and through which liquid flows out of the liquid reservoir;
A metering unit provided opposite to the end of the first channel opposite to the liquid reservoir side, and weighing out a predetermined amount of the liquid;
A receiving part into which the liquid weighed in the measuring part flows;
A second flow path for flowing the liquid weighed in the measuring section to the receiving section,
The second flow path is provided with an inspection object receiving portion having a cross-sectional area enlarged portion in which a cross-sectional area of the flow path continuously increases from the measuring section side toward the receiving section. body.   The cross-sectional area enlargement portion of the second flow path is such that the cross-sectional area of the flow path is continuously expanded by continuously increasing the depth of the flow path in the thickness direction of the plate member. The test object receptacle according to claim 1, wherein:   The test object receptacle according to claim 1, wherein the cross-sectional area enlarged portion of the second flow path starts from an end portion of the opening portion of the measuring portion on the receiving portion side. In a state where a centrifugal force is applied so that the liquid flows from the liquid reservoir to the measuring unit,
The inspection object receptacle according to any one of claims 1 to 3, wherein an inflection point with respect to an upstream direction of centrifugal force is provided in the middle of the second flow path. The test object receiver further includes:
A surplus part for storing liquid overflowing from the measuring part;
A third flow path for flowing the liquid overflowing from the measuring section to the surplus section,
The cross-sectional area enlarged portion in which the cross-sectional area of the flow path continuously increases from the measuring section side to the surplus section is provided in the third flow path. To 4. The test object receiver according to any one of 1 to 4.   The cross-sectional area enlargement portion of the third flow path has the cross-sectional area of the flow path continuously expanded by continuously increasing the depth of the flow path in the thickness direction of the plate member. The test object receiver according to claim 5, wherein:   The test object receptacle according to claim 5 or 6, wherein the cross-sectional area enlarged portion of the third flow path starts from an end portion of the opening portion of the measuring portion on the surplus portion side.

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