JP2012031131A5 - - Google Patents

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Publication number
JP2012031131A5
JP2012031131A5 JP2011017776A JP2011017776A JP2012031131A5 JP 2012031131 A5 JP2012031131 A5 JP 2012031131A5 JP 2011017776 A JP2011017776 A JP 2011017776A JP 2011017776 A JP2011017776 A JP 2011017776A JP 2012031131 A5 JP2012031131 A5 JP 2012031131A5
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JP
Japan
Prior art keywords
salt
loxoprofen
pharmaceutical composition
chlorpheniramine
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011017776A
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Japanese (ja)
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JP2012031131A (en
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Publication date
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Priority to JP2011017776A priority Critical patent/JP2012031131A/en
Priority claimed from JP2011017776A external-priority patent/JP2012031131A/en
Publication of JP2012031131A publication Critical patent/JP2012031131A/en
Publication of JP2012031131A5 publication Critical patent/JP2012031131A5/ja
Pending legal-status Critical Current

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Claims (11)

クロルフェニラミン又はその塩と、ロキソプロフェン又はその塩とを実質的に互いに接しないように含有する医薬組成物。 Click Rorufeniramin or a salt thereof, loxoprofen or a pharmaceutical composition containing as substantially in contact with each other and their salts. ロキソプロフェン又はその塩が、ロキソプロフェンナトリウム水和物である請求項１記載の医薬組成物。   The pharmaceutical composition according to claim 1, wherein the loxoprofen or a salt thereof is loxoprofen sodium hydrate. ロキソプロフェン又はその塩を、ロキソプロフェンナトリウム無水物換算で、１０〜３００ｍｇを１日量として含有する請求項１又は２記載の医薬組成物。 The pharmaceutical composition according to claim 1 or 2, wherein loxoprofen or a salt thereof is contained in an amount of 10 to 300 mg per day in terms of anhydrous loxoprofen sodium. クロルフェニラミン又はその塩が、ｄ−クロルフェニラミンマレイン酸塩及びｄｌ−クロルフェニラミンマレイン酸塩から選ばれる１種以上である請求項１〜３いずれか１項記載の医薬組成物。The pharmaceutical composition according to any one of claims 1 to 3, wherein the chlorpheniramine or a salt thereof is at least one selected from d-chlorpheniramine maleate and dl-chlorpheniramine maleate. ｄ−クロルフェニラミンマレイン酸塩を、０．１〜１５ｍｇを１日量として含有する請求項４項記載の医薬組成物。The pharmaceutical composition according to claim 4, comprising 0.1 to 15 mg of d-chlorpheniramine maleate as a daily dose. ｄｌ−クロルフェニラミンマレイン酸塩を、０．５〜２０ｍｇを１日量として含有する請求項４記載の医薬組成物。The pharmaceutical composition according to claim 4, comprising 0.5 to 20 mg of dl-chlorpheniramine maleate as a daily dose. ロキソプロフェン又はその塩が、ロキソプロフェン又はその塩を含有する粒状物である請求項１〜６いずれか１項記載の医薬組成物。 The pharmaceutical composition according to any one of claims 1 to 6 , wherein the loxoprofen or a salt thereof is a granular material containing loxoprofen or a salt thereof. クロルフェニラミン又はその塩が、クロルフェニラミン又はその塩を含有する粒状物である請求項１〜７いずれか１項記載の医薬組成物。The pharmaceutical composition according to any one of claims 1 to 7, wherein the chlorpheniramine or a salt thereof is a granular material containing chlorpheniramine or a salt thereof. （Ａ）ロキソプロフェン若しくはその塩そのもの、又はロキソプロフェン若しくはその塩を含有する固形組成物と、（Ｂ）クロルフェニラミン若しくはその塩そのもの、又はクロルフェニラミン若しくはその塩を含有する固形組成物とを含有し、これらの固形組成物を構成する成分によって、ロキソプロフェン又はその塩とクロルフェニラミン又はその塩とが互いに接しないように配置されている医薬組成物（但し、成分（Ａ）がロキソプロフェン又はその塩そのものであり、かつ成分（Ｂ）がクロルフェニラミン又はその塩そのものである場合を除く）。(A) Loxoprofen or a salt thereof, or a solid composition containing loxoprofen or a salt thereof, and (B) a solid composition containing chlorpheniramine or a salt thereof, or chlorpheniramine or a salt thereof. The pharmaceutical composition in which loxoprofen or a salt thereof and chlorpheniramine or a salt thereof are arranged so as not to contact each other depending on the components constituting these solid compositions (provided that component (A) is a loxoprofen or a salt thereof itself) And the component (B) is chlorpheniramine or a salt thereof). 固形製剤である請求項１〜９いずれか１項記載の医薬組成物。 The pharmaceutical composition according to any one of claims 1 to 9, which is a solid preparation. 剤形が、カプセル剤、丸剤、顆粒剤、細粒剤、散剤又は錠剤である請求項１〜１０いずれか１項記載の医薬組成物。 The pharmaceutical composition according to any one of claims 1 to 10 , wherein the dosage form is a capsule, pill, granule, fine granule, powder or tablet.
JP2011017776A 2010-01-29 2011-01-31 Loxoprofen-containing pharmaceutical composition Pending JP2012031131A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2011017776A JP2012031131A (en) 2010-01-29 2011-01-31 Loxoprofen-containing pharmaceutical composition

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
JP2010018015 2010-01-29
JP2010018015 2010-01-29
JP2010149115 2010-06-30
JP2010149061 2010-06-30
JP2010149089 2010-06-30
JP2010149115 2010-06-30
JP2010149061 2010-06-30
JP2010149089 2010-06-30
JP2011017776A JP2012031131A (en) 2010-01-29 2011-01-31 Loxoprofen-containing pharmaceutical composition

Publications (2)

Publication Number Publication Date
JP2012031131A JP2012031131A (en) 2012-02-16
JP2012031131A5 true JP2012031131A5 (en) 2013-03-14

Family

ID=44319475

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2011512760A Active JP4787912B2 (en) 2010-01-29 2011-01-31 Loxoprofen-containing pharmaceutical composition
JP2011017776A Pending JP2012031131A (en) 2010-01-29 2011-01-31 Loxoprofen-containing pharmaceutical composition
JP2011136591A Pending JP2012031147A (en) 2010-01-29 2011-06-20 Loxoprofen-containing pharmaceutical composition
JP2013182739A Active JP5575961B2 (en) 2010-01-29 2013-09-04 Loxoprofen-containing pharmaceutical composition
JP2014130149A Active JP5809736B2 (en) 2010-01-29 2014-06-25 New pharmaceutical composition containing loxoprofen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2011512760A Active JP4787912B2 (en) 2010-01-29 2011-01-31 Loxoprofen-containing pharmaceutical composition

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2011136591A Pending JP2012031147A (en) 2010-01-29 2011-06-20 Loxoprofen-containing pharmaceutical composition
JP2013182739A Active JP5575961B2 (en) 2010-01-29 2013-09-04 Loxoprofen-containing pharmaceutical composition
JP2014130149A Active JP5809736B2 (en) 2010-01-29 2014-06-25 New pharmaceutical composition containing loxoprofen

Country Status (4)

Country Link
JP (5) JP4787912B2 (en)
KR (1) KR20120112644A (en)
CN (1) CN102740854A (en)
WO (1) WO2011093498A1 (en)

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JP5525323B2 (en) * 2009-04-28 2014-06-18 興和株式会社 Loxoprofen-containing pharmaceutical preparation
JP5624367B2 (en) * 2009-05-28 2014-11-12 興和株式会社 Loxoprofen-containing pharmaceutical preparation
TWI680757B (en) * 2010-12-28 2020-01-01 日商興和股份有限公司 Antipyretic and analgesic composition
WO2013018766A1 (en) * 2011-07-29 2013-02-07 興和株式会社 Stable pharmaceutical composition
JP6008857B2 (en) * 2011-07-29 2016-10-19 興和株式会社 Pharmaceutical composition containing loxoprofen
JP6087826B2 (en) * 2011-09-29 2017-03-01 興和株式会社 Pharmaceutical composition containing loxoprofen or a salt thereof
JP6114573B2 (en) * 2012-02-29 2017-04-12 第一三共ヘルスケア株式会社 Solid formulation containing loxoprofen sodium and antacid
WO2014002599A1 (en) * 2012-06-25 2014-01-03 興和株式会社 Crude-drug-containing pharmaceutical composition
JP6149625B2 (en) * 2012-11-09 2017-06-21 大正製薬株式会社 Pharmaceutical composition
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JP6252177B2 (en) * 2013-01-28 2017-12-27 大正製薬株式会社 Solid preparation
CN103333064B (en) * 2013-07-17 2014-04-23 珠海金鸿药业股份有限公司 Loxoprofen sodium compound and pharmaceutical composition thereof
CN104224740A (en) * 2014-09-28 2014-12-24 白杨 Preparation method for lilium compound antiphlogistic pill with treated coating
CN104225160A (en) * 2014-09-28 2014-12-24 白杨 Method for preparing coating-treated seven-ingredient qi tonifying pill
CN104257984A (en) * 2014-09-28 2015-01-07 白杨 Method for preparing six-ingredient rehmannia pills subjected to coating treatment
CN104225162A (en) * 2014-09-28 2014-12-24 白杨 Preparation method for cinnamon and monkshood rehmannia pill with treated coating
CN104288433A (en) * 2014-09-28 2015-01-21 白杨 Preparation method of coated Goujudihuang pill
CN104225161A (en) * 2014-09-28 2014-12-24 白杨 Preparation method for angelica sinensis and paeonia lactiflora rehmannia pill with treated coating
CN104225187A (en) * 2014-09-28 2014-12-24 白杨 Preparation method of rhizoma anemarrhenae and golden cypress rehmannia pill with treated coating
CN106580968A (en) * 2016-11-22 2017-04-26 郑州仁宏医药科技有限公司 Western medicine powder for treating swelling and aching of gum and preparation method thereof
EP3415143A1 (en) * 2017-06-16 2018-12-19 Kai-Uwe Kern Bromhexine for the treatment of pain
CN113332252A (en) * 2021-06-07 2021-09-03 大桐制药（中国）有限责任公司 Preparation method of loxoprofen sodium tablets

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