CN104288433A - Preparation method of coated Goujudihuang pill - Google Patents

Preparation method of coated Goujudihuang pill Download PDF

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Publication number
CN104288433A
CN104288433A CN201410508188.0A CN201410508188A CN104288433A CN 104288433 A CN104288433 A CN 104288433A CN 201410508188 A CN201410508188 A CN 201410508188A CN 104288433 A CN104288433 A CN 104288433A
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parts
pill
chinese holly
goujudihuang
dihuang ball
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白杨
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/40Cornaceae (Dogwood family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/884Alismataceae (Water-plantain family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • Insects & Arthropods (AREA)
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  • Medicines Containing Plant Substances (AREA)
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Abstract

The invention relates to a preparation method of a coated Goujudihuang pill (consisting of fruit of Chinese wolfberry, chrysanthemum and rehmannia). The preparation method comprises the following steps: (1) grinding raw materials of the Goujudihuang pill to obtain raw material powder, adding refined honey, uniformly mixing and pelleting to obtain Goujudihuang pill; (2) covering a coating layer on the surface of the Goujudihuang pill to obtain coated Goujudihuang pill; and (3) covering a spleen tonifying medicine layer on the surface of the coated Goujudihuang pill to obtain the required coated Goujudihuang pill. By coating a conventional Goujudihuang pill through a medicinal accessory thin film coating material and by covering the spleen tonifying medicine layer, the prepared coated Goujudihuang pill is relatively low in side effect; and practical application shows that the coated Goujudihuang pill, as taken for long time, and can be used for not only achieving a treatment effect of taking the Goujudihuang pill, but also greatly reducing a side effect causing stomach cold or digestion obstruction.

Description

A kind of preparation method of Chinese holly Ju Dihuang ball of Cotton seeds
Technical field
The present invention relates to a kind of preparation method of Chinese holly Ju Dihuang ball of Cotton seeds, belong to technical field of Chinese medicine.
Background technology
The traditional Chinese medical science is thought: liver opening at eye, liver blood is noted and then can look in order, namely the function of eyes and liver closely related; In Five elements theory, the liver belonging to wood, kidney belongs to water, and water can give birth to wood, and kidney and liver are a pair mother child relations, and namely liver is the son of kidney, and kidney is the mother of liver, and it is dirty that female disease of ZANG-organs change can have influence on son; Liver storing blood again, kidney controlling essence storage, essence, blood alternate, therefore liver and kidney closely related; Therefore, treatment ocular disease, often starts with from Liver and kidney.QIJU DIHUANG WAN adds Fructus Lycii by LIUWEI DIHUANG WAN, Flos Chrysanthemi forms.Fructus Lycii: Gan Pingzhi moistens, and enters lung, liver, kidney channel, the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity; Flos Chrysanthemi: pungent, bitter, sweet, is slightly cold, the kind clear sharp head, the heat of the loose Liver Channel of a surname, suppressing the hyperactive liver improving eyesight.Eight kinds of compatibility of drugs combinations play the effect of YIN nourishing, nourishing the liver, improving eyesight jointly, to the hepatic and renal YIN deficiency simultaneously with the heads such as obvious dizzy blurring of vision, eye part disease, particularly effectively.
But because Chinese holly Ju Dihuang ball belongs to sweet warm nature, the relatively medicine of nourishing YIN, cure mainly deficiency of the kidney yin, in its formula, cloudy soft medicine is more, so sometimes can antidigestive side effect after eating, therefore not only spleen and stomach function is weak, dyspepsia person is careful eats, and long-term taking can cause the malaise symptoms such as abdominal distention, loose stool, inappetence.
Summary of the invention
The present invention is directed to the deficiencies in the prior art, a kind of preparation method of Chinese holly Ju Dihuang ball of Cotton seeds is provided.
Technical solution of the present invention is as follows:
A preparation method for the Chinese holly Ju Dihuang ball of Cotton seeds, step is as follows:
(1) by Chinese holly Ju Dihuang ball raw material after crushed, obtained material powder, then adds refined honey, mix homogeneously, pill, obtained Chinese holly Ju Dihuang ball;
(2) coatings of degrading after Chinese holly Ju Dihuang ball Surface coating one deck that step (1) is obtained exists 30 ~ 60min in vivo, obtained coating Chinese holly Ju Dihuang ball;
(3) in coating Chinese holly Ju Dihuang ball Surface coating one deck drugs strengthening spleen bed of material that step (2) is obtained, the weight ratio of the described drugs strengthening spleen bed of material and Chinese holly Ju Dihuang ball is (0.1 ~ 1): 1, the Chinese holly Ju Dihuang ball of obtained Cotton seeds.
Preferred according to the present invention, the Chinese holly Ju Dihuang ball raw material of described step (1) is as follows, is weight portion:
Fructus Lycii 40 parts, Flos Chrysanthemi 40 parts, Radix Rehmanniae Preparata 160 parts, Fructus Corni (processed) (wine Fructus Corni) 80 parts, Cortex Moutan 60 parts, Rhizoma Dioscoreae 80 parts, 60 parts, Poria, Rhizoma Alismatis 60 parts, refined honey 7 ~ 10 parts.
Preferred according to the present invention, the Chinese holly Ju Dihuang ball raw material of described step (1) is as follows, is weight portion:
Fructus Lycii 40 parts, Flos Chrysanthemi 40 parts, Radix Rehmanniae Preparata 160 parts, Fructus Corni (processed) (wine Fructus Corni) 80 parts, Cortex Moutan 60 parts, Rhizoma Dioscoreae 80 parts, 60 parts, Poria, Rhizoma Alismatis 60 parts, refined honey 16 ~ 22 parts.
It is coated that coatings in described step (2) can adopt the pharmaceutic adjuvant film coating material of prior art to adopt existing coating equipment in sugar production line to carry out.
Preferred according to the present invention, described drugs strengthening spleen bed of material component is as follows, is weight portion:
Radix Pseudostellariae 3 ~ 5 parts, 1 part, Radix Glycyrrhizae, binding agent 3 ~ 5 parts.
Preferred further according to the present invention, described binding agent is dextrin.
Beneficial effect
The present invention carries out coating and the coated drugs strengthening spleen bed of material by carrying out pharmaceutic adjuvant film coating material to traditional Chinese holly Ju Dihuang ball, thus after spleen invigorating composition is discharged, after 30 ~ 60min, just discharge the composition of Chinese holly Ju Dihuang ball, obtain the Chinese holly Ju Dihuang ball of the less Cotton seeds of side effect, through practical application, the Chinese holly Ju Dihuang ball of this Cotton seeds of long-term taking can not only reach takes Chinese holly Ju Dihuang pill for curing effect, and cause cold syndrome of the stomach, hinder digestion side effect also reduced greatly.
Detailed description of the invention
Below in conjunction with embodiment, technical scheme of the present invention is described further, but institute of the present invention protection domain is not limited thereto.
Embodiment 1
A preparation method for the Chinese holly Ju Dihuang ball of Cotton seeds, step is as follows:
(1) by Chinese holly Ju Dihuang ball raw material after crushed, obtained material powder, then adds refined honey, mix homogeneously, pill, obtained Chinese holly Ju Dihuang ball;
(2) coatings of degrading after Chinese holly Ju Dihuang ball Surface coating one deck that step (1) is obtained exists 30min in vivo, obtained coating Chinese holly Ju Dihuang ball;
(3) in coating Chinese holly Ju Dihuang ball Surface coating one deck drugs strengthening spleen bed of material that step (2) is obtained, the weight ratio of the described drugs strengthening spleen bed of material and Chinese holly Ju Dihuang ball is 0.1:1, the Chinese holly Ju Dihuang ball of obtained Cotton seeds.
The Chinese holly Ju Dihuang ball raw material of described step (1) is as follows, is weight portion:
Fructus Lycii 40 parts, Flos Chrysanthemi 40 parts, Radix Rehmanniae Preparata 160 parts, Fructus Corni (processed) (wine Fructus Corni) 80 parts, Cortex Moutan 60 parts, Rhizoma Dioscoreae 80 parts, 60 parts, Poria, Rhizoma Alismatis 60 parts, refined honey 7 parts.
Described drugs strengthening spleen bed of material component is as follows, is weight portion:
Radix Pseudostellariae 3 parts, 1 part, Radix Glycyrrhizae, 3 parts, dextrin.
Embodiment 2
A preparation method for the Chinese holly Ju Dihuang ball of Cotton seeds, step is as follows:
(1) by Chinese holly Ju Dihuang ball raw material after crushed, obtained material powder, then adds refined honey, mix homogeneously, pill, obtained Chinese holly Ju Dihuang ball;
(2) coatings of degrading after Chinese holly Ju Dihuang ball Surface coating one deck that step (1) is obtained exists 60min in vivo, obtained coating Chinese holly Ju Dihuang ball;
(3) in coating Chinese holly Ju Dihuang ball Surface coating one deck drugs strengthening spleen bed of material that step (2) is obtained, the weight ratio of the described drugs strengthening spleen bed of material and Chinese holly Ju Dihuang ball is 1:1, the Chinese holly Ju Dihuang ball of obtained Cotton seeds.
The Chinese holly Ju Dihuang ball raw material of described step (1) is as follows, is weight portion:
Fructus Lycii 40 parts, Flos Chrysanthemi 40 parts, Radix Rehmanniae Preparata 160 parts, Fructus Corni (processed) (wine Fructus Corni) 80 parts, Cortex Moutan 60 parts, Rhizoma Dioscoreae 80 parts, 60 parts, Poria, Rhizoma Alismatis 60 parts, refined honey 22 parts.
Preferred according to the present invention, described drugs strengthening spleen bed of material component is as follows, is weight portion:
Radix Pseudostellariae 5 parts, 1 part, Radix Glycyrrhizae, 5 parts, dextrin.
Embodiment 3
A preparation method for the Chinese holly Ju Dihuang ball of Cotton seeds, step is as follows:
(1) by Chinese holly Ju Dihuang ball raw material after crushed, obtained material powder, then adds refined honey, mix homogeneously, pill, obtained Chinese holly Ju Dihuang ball;
(2) coatings of degrading after Chinese holly Ju Dihuang ball Surface coating one deck that step (1) is obtained exists 45min in vivo, obtained coating Chinese holly Ju Dihuang ball;
(3) in coating Chinese holly Ju Dihuang ball Surface coating one deck drugs strengthening spleen bed of material that step (2) is obtained, the weight ratio of the described drugs strengthening spleen bed of material and Chinese holly Ju Dihuang ball is 0.5:1, the Chinese holly Ju Dihuang ball of obtained Cotton seeds.
The Chinese holly Ju Dihuang ball raw material of described step (1) is as follows, is weight portion:
Fructus Lycii 40 parts, Flos Chrysanthemi 40 parts, Radix Rehmanniae Preparata 160 parts, Fructus Corni (processed) (wine Fructus Corni) 80 parts, Cortex Moutan 60 parts, Rhizoma Dioscoreae 80 parts, 60 parts, Poria, Rhizoma Alismatis 60 parts, refined honey 16 parts.
Preferred according to the present invention, described drugs strengthening spleen bed of material component is as follows, is weight portion:
Radix Pseudostellariae 4 parts, 1 part, Radix Glycyrrhizae, 4 parts, dextrin.
Test example 1
Lu, man, Zibo people from Zichuan District, soreness of the waist and knees, two skelasthenia, dizzy blurring of vision, spleen and stomach function is normal.Take the Chinese holly Ju Dihuang ball of the Cotton seeds described in embodiment 2, every day three times, with each 6 grams of Chinese holly Ju Dihuang ball weighing scale, take one month, symptom is obviously improved, and spleen and stomach function is normal.
Poplar, man, people from Zhangdian District, Zibo, long-term taking Chinese holly Ju Dihuang ball causes the symptom of cold syndrome of the stomach, abdominal distention, loose stool, inappetence.Take the Chinese holly Ju Dihuang ball of the Cotton seeds described in embodiment 1, every day three times, with each 6 grams of Chinese holly Ju Dihuang ball weighing scale, take one month, the symptom of cold syndrome of the stomach, abdominal distention, loose stool, inappetence alleviates gradually.
Test example 2
Having remarkable deficiency of the kidney yin through 50 causes the patient of blurred vision to take the Chinese holly Ju Dihuang ball of Cotton seeds described in embodiment 2, taken three times a day, each 6 grams, takes one month, is designated as group 1.Simultaneously 50 have remarkable deficiency of the kidney yin and cause the patient of blurred vision to take common commercially available Chinese holly Ju Dihuang ball, and by specification is taken, and is designated as group 2.Result is as shown in table 1.
Table 1
? Deficiency of the kidney yin, blurred vision symptom are improved (people) Deficiency and coldness of spleen and stomach symptom (people)
Group 1 47 0
Group 2 46 15
Interpretation of result
As can be seen from Table 1, group 1 and group 2 all obviously can improve the symptom of deficiency of the kidney yin patient, but existing commercially available Chinese holly Ju Dihuang ball can cause part to take the symptom that patient produces cold syndrome of the stomach, abdominal distention, loose stool, inappetence, and taking the Chinese holly Ju Dihuang ball of the Cotton seeds described in embodiment 2, the patient that takes producing above-mentioned symptom obviously reduces.

Claims (5)

1. a preparation method for the Chinese holly Ju Dihuang ball of Cotton seeds, step is as follows:
(1) by Chinese holly Ju Dihuang ball raw material after crushed, obtained material powder, then adds refined honey, mix homogeneously, pill, obtained Chinese holly Ju Dihuang ball;
(2) coatings of degrading after Chinese holly Ju Dihuang ball Surface coating one deck that step (1) is obtained exists 30 ~ 60min in vivo, obtained coating Chinese holly Ju Dihuang ball;
(3) in coating Chinese holly Ju Dihuang ball Surface coating one deck drugs strengthening spleen bed of material that step (2) is obtained, the weight ratio of the described drugs strengthening spleen bed of material and Chinese holly Ju Dihuang ball is (0.1 ~ 1): 1, the Chinese holly Ju Dihuang ball of obtained Cotton seeds.
2. preparation method as claimed in claim 1, it is characterized in that, the Chinese holly Ju Dihuang ball raw material of described step (1) is as follows, is weight portion:
Fructus Lycii 40 parts, Flos Chrysanthemi 40 parts, Radix Rehmanniae Preparata 160 parts, Fructus Corni (processed) (wine Fructus Corni) 80 parts, Cortex Moutan 60 parts, Rhizoma Dioscoreae 80 parts, 60 parts, Poria, Rhizoma Alismatis 60 parts, refined honey 7 ~ 10 parts.
3. preparation method as claimed in claim 1, it is characterized in that, the Chinese holly Ju Dihuang ball raw material of described step (1) is as follows, is weight portion:
Fructus Lycii 40 parts, Flos Chrysanthemi 40 parts, Radix Rehmanniae Preparata 160 parts, Fructus Corni (processed) (wine Fructus Corni) 80 parts, Cortex Moutan 60 parts, Rhizoma Dioscoreae 80 parts, 60 parts, Poria, Rhizoma Alismatis 60 parts, refined honey 16 ~ 22 parts.
4. preparation method as claimed in claim 1, it is characterized in that, described drugs strengthening spleen bed of material component is as follows, is weight portion:
Radix Pseudostellariae 3 ~ 5 parts, 1 part, Radix Glycyrrhizae, binding agent 3 ~ 5 parts.
5. preparation method as claimed in claim 4, it is characterized in that, described binding agent is dextrin.
CN201410508188.0A 2014-09-28 2014-09-28 Preparation method of coated Goujudihuang pill Pending CN104288433A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104872683A (en) * 2015-06-12 2015-09-02 广东岭南职业技术学院 Fructus lycii containing six traditional Chinese medicinal materials and preparation method of fructus lycii

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN87106202A (en) * 1987-09-05 1988-02-24 广州陈李济药厂 The preparation technology of Chinese patent medicine gastrointestinal tomach-solvable type and intestinn-solvable type pill
CN101601641A (en) * 2008-06-11 2009-12-16 重庆华邦制药股份有限公司 A kind of medical solid compound preparation and preparation method thereof
CN202314480U (en) * 2011-09-25 2012-07-11 烟台大洋制药有限公司 Improved rheumatism elimination and itch relieving granule
CN102740854A (en) * 2010-01-29 2012-10-17 兴和株式会社 Loxoprofen-containing pharmaceutical composition

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN87106202A (en) * 1987-09-05 1988-02-24 广州陈李济药厂 The preparation technology of Chinese patent medicine gastrointestinal tomach-solvable type and intestinn-solvable type pill
CN101601641A (en) * 2008-06-11 2009-12-16 重庆华邦制药股份有限公司 A kind of medical solid compound preparation and preparation method thereof
CN102740854A (en) * 2010-01-29 2012-10-17 兴和株式会社 Loxoprofen-containing pharmaceutical composition
CN202314480U (en) * 2011-09-25 2012-07-11 烟台大洋制药有限公司 Improved rheumatism elimination and itch relieving granule

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
国家药典委员会编: "《中国药典 一部标准(2010年版)》", 31 January 2010, 化学工业出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104872683A (en) * 2015-06-12 2015-09-02 广东岭南职业技术学院 Fructus lycii containing six traditional Chinese medicinal materials and preparation method of fructus lycii

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