JP2012012417A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012012417A5 JP2012012417A5 JP2011227135A JP2011227135A JP2012012417A5 JP 2012012417 A5 JP2012012417 A5 JP 2012012417A5 JP 2011227135 A JP2011227135 A JP 2011227135A JP 2011227135 A JP2011227135 A JP 2011227135A JP 2012012417 A5 JP2012012417 A5 JP 2012012417A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- independently
- occurrence
- optionally substituted
- nrco
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 14
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 5
- 125000001118 alkylidene group Chemical group 0.000 claims 5
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 3
- 125000001931 aliphatic group Chemical group 0.000 claims 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 3
- 125000005842 heteroatom Chemical group 0.000 claims 3
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 claims 3
- 229910052757 nitrogen Inorganic materials 0.000 claims 3
- 229910052760 oxygen Inorganic materials 0.000 claims 3
- 239000001301 oxygen Chemical group 0.000 claims 3
- 229920006395 saturated elastomer Polymers 0.000 claims 3
- 229910052717 sulfur Chemical group 0.000 claims 3
- 239000011593 sulfur Chemical group 0.000 claims 3
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000002950 monocyclic group Chemical group 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 125000004429 atom Chemical group 0.000 claims 1
- 125000002619 bicyclic group Chemical group 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 125000002757 morpholinyl group Chemical group 0.000 claims 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims 1
- 125000004193 piperazinyl group Chemical group 0.000 claims 1
- 125000003386 piperidinyl group Chemical group 0.000 claims 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 claims 1
- 0 *c1c(-c2c[n]c3c2c(*)c(*)cn3)nc(*)[s]1 Chemical compound *c1c(-c2c[n]c3c2c(*)c(*)cn3)nc(*)[s]1 0.000 description 1
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58438304P | 2004-06-30 | 2004-06-30 | |
| US60/584,383 | 2004-06-30 | ||
| US58472104P | 2004-07-01 | 2004-07-01 | |
| US60/584,721 | 2004-07-01 | ||
| US11/098,751 US7514448B2 (en) | 2004-04-02 | 2005-04-04 | Azaindoles useful as inhibitors of rock and other protein kinases |
| USPCT/US05/11358 | 2005-04-04 | ||
| PCT/US2005/011358 WO2005103050A2 (en) | 2004-04-02 | 2005-04-04 | Azaindoles useful as inhibitors of rock and other protein kinases |
| US11/098,751 | 2005-04-04 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007519460A Division JP5122280B2 (ja) | 2004-06-30 | 2005-06-29 | タンパク質キナーゼのインヒビターとして有用なアザインドール |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013001760A Division JP2013064015A (ja) | 2004-06-30 | 2013-01-09 | タンパク質キナーゼのインヒビターとして有用なアザインドール |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012012417A JP2012012417A (ja) | 2012-01-19 |
| JP2012012417A5 true JP2012012417A5 (enrdf_load_stackoverflow) | 2013-02-28 |
Family
ID=37801682
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007519460A Expired - Fee Related JP5122280B2 (ja) | 2004-06-30 | 2005-06-29 | タンパク質キナーゼのインヒビターとして有用なアザインドール |
| JP2011227135A Pending JP2012012417A (ja) | 2004-06-30 | 2011-10-14 | タンパク質キナーゼのインヒビターとして有用なアザインドール |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007519460A Expired - Fee Related JP5122280B2 (ja) | 2004-06-30 | 2005-06-29 | タンパク質キナーゼのインヒビターとして有用なアザインドール |
Country Status (4)
| Country | Link |
|---|---|
| JP (2) | JP5122280B2 (enrdf_load_stackoverflow) |
| IL (1) | IL180303A0 (enrdf_load_stackoverflow) |
| MX (1) | MX2007000092A (enrdf_load_stackoverflow) |
| NO (1) | NO20070502L (enrdf_load_stackoverflow) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2007000092A (es) * | 2004-06-30 | 2007-03-07 | Vertex Pharma | Azaindoles utiles como inhibidores de proteinas cinasas. |
| EP1781287A4 (en) * | 2004-08-13 | 2008-02-27 | Genentech Inc | THIAZOLE-BASED COMPOUNDS HAVING ENZYMATIC INHIBITORY ACTIVITY USING ADENOSINE TRIPHOSPHATE (ATP) |
| DE102008038221A1 (de) * | 2008-08-18 | 2010-02-25 | Merck Patent Gmbh | 7-Azaindolderivate |
| DE102009058280A1 (de) * | 2009-12-14 | 2011-06-16 | Merck Patent Gmbh | Thiazolderivate |
| AU2011239966B2 (en) | 2010-04-16 | 2014-05-08 | Ac Immune S.A. | Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins |
| EP2585468A1 (en) * | 2010-06-23 | 2013-05-01 | Vertex Pharmaceuticals Incorporated | Pyrrolo- pyrazine derivatives useful as inhibitors of atr kinase |
| DE102011105469A1 (de) * | 2011-06-24 | 2012-12-27 | Merck Patent Gmbh | 7-Azaindolderivate |
| SG11201407919WA (en) * | 2012-05-31 | 2014-12-30 | Phenex Pharmaceuticals Ag | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ror[gamma] |
| MX363295B (es) * | 2014-02-04 | 2019-03-15 | Taiho Pharmaceutical Co Ltd | Derivado de azaindol. |
| JP2023545219A (ja) * | 2020-10-05 | 2023-10-26 | エンライブン インコーポレイテッド | Ｂｃｒ－ａｂｌチロシンキナーゼの阻害のための７－アザインドール化合物 |
| WO2023110843A1 (en) * | 2021-12-15 | 2023-06-22 | Almirall, S.A. | Heterobicyclic derivatives as itk inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6265403B1 (en) * | 1999-01-20 | 2001-07-24 | Merck & Co., Inc. | Angiogenesis inhibitors |
| DE60136530D1 (de) * | 2000-03-01 | 2008-12-24 | Janssen Pharmaceutica Nv | 2,4-disubstituierte thiazolyl derivate |
| SE0202463D0 (sv) * | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | Novel compounds |
| US7514448B2 (en) * | 2004-04-02 | 2009-04-07 | Vertex Pharmaceuticals Incorporated | Azaindoles useful as inhibitors of rock and other protein kinases |
| MX2007000092A (es) * | 2004-06-30 | 2007-03-07 | Vertex Pharma | Azaindoles utiles como inhibidores de proteinas cinasas. |
-
2005
- 2005-06-29 MX MX2007000092A patent/MX2007000092A/es active IP Right Grant
- 2005-06-29 JP JP2007519460A patent/JP5122280B2/ja not_active Expired - Fee Related
-
2006
- 2006-12-25 IL IL180303A patent/IL180303A0/en unknown
-
2007
- 2007-01-26 NO NO20070502A patent/NO20070502L/no not_active Application Discontinuation
-
2011
- 2011-10-14 JP JP2011227135A patent/JP2012012417A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012012417A5 (enrdf_load_stackoverflow) | ||
| MX2021013075A (es) | Oxisteroles y metodos de uso de los mismos. | |
| WO2012003405A4 (en) | Sgc stimulators | |
| MX2012009186A (es) | Pirrolidina-2-carboxamidas sustituidas. | |
| JP2011137045A5 (enrdf_load_stackoverflow) | ||
| PH12013501196B1 (en) | Indeno- fused ring compounds having photochromic properties | |
| MX2009009492A (es) | Compuestos organicos biciclicos adecuados para el tratamiento de condiciones inflamatorias o alergicas. | |
| EA201492285A1 (ru) | Соединения n-алкилтриазола в качестве антагонистов лизофосфатидной кислоты (lpar) | |
| AR084639A1 (es) | Formas polimorficas de acido 2-(5-bromo-4-(4-ciclopropilnaftalen-1-il)-4h-1,2,4-triazol-3-iltio)acetico y usos del mismo | |
| ECSP12011684A (es) | Inhibidores de los virus flaviviridae. | |
| JP2015537008A5 (enrdf_load_stackoverflow) | ||
| MX395406B (es) | Compuestos de piperidinobenzodiazepina con actividad antiproliferativa. | |
| MX382122B (es) | Oxiesteroles y metodos de uso de los mismos. | |
| HK1255500A1 (zh) | 氧固醇及其使用方法 | |
| WO2012101011A3 (en) | New aryl-benzocycloalkyl amide derivatives | |
| JP2013532130A5 (enrdf_load_stackoverflow) | ||
| CY1125198T1 (el) | Ενωσεις και αναλογα 1-ετεροκυκλικου ισοχρωμανυλιου για την αντιμετωπιση διαταραχων του κνς | |
| JP2016537382A5 (enrdf_load_stackoverflow) | ||
| JP2015508092A5 (enrdf_load_stackoverflow) | ||
| CY1117688T1 (el) | Ενωσεις τετραϋδροπυρρολοθειαζινης | |
| JP2015500842A5 (enrdf_load_stackoverflow) | ||
| EA201301315A1 (ru) | Способ получения промежуточных соединений эстетрола | |
| JP2015535847A5 (enrdf_load_stackoverflow) | ||
| WO2013152277A3 (en) | Moenomycin analogs, methods of synthesis, and uses thereof | |
| PE20150182A1 (es) | Compuestos de fenoxietil piperidina |