JP2011529942A - ピリジン誘導体の結晶体 - Google Patents
ピリジン誘導体の結晶体 Download PDFInfo
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- JP2011529942A JP2011529942A JP2011521561A JP2011521561A JP2011529942A JP 2011529942 A JP2011529942 A JP 2011529942A JP 2011521561 A JP2011521561 A JP 2011521561A JP 2011521561 A JP2011521561 A JP 2011521561A JP 2011529942 A JP2011529942 A JP 2011529942A
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- crystalline form
- compound
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- methylbenzenesulfonate
- Prior art date
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- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0814340.6A GB0814340D0 (en) | 2008-08-05 | 2008-08-05 | Anhydrous crystol form fo a pyridine derivative |
| GB0814340.6 | 2008-08-05 | ||
| PCT/EP2009/060089 WO2010015626A1 (en) | 2008-08-05 | 2009-08-04 | Crystalline forms of a pyridine derivative |
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| JP2011529942A5 JP2011529942A5 (enExample) | 2012-09-27 |
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| WO (1) | WO2010015626A1 (enExample) |
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| ES2440938T3 (es) * | 2009-08-27 | 2014-01-31 | Nerre Therapeutics Limited | Formas anhidrato de un derivado de piridina |
| AU2016264034B2 (en) * | 2015-05-18 | 2020-03-05 | KaNDy Therapeutics Limited | Dual NK-1/NK-3 receptor antagonists for the treatment of sex-hormone-dependent diseases |
| EA202092131A1 (ru) | 2018-03-14 | 2020-11-27 | Кэнди Терапьютикс Лимитед | Новый фармацевтический препарат, содержащий двойные антагонисты рецептора nk-1/nk-3 |
| EP4058433A1 (en) * | 2019-11-15 | 2022-09-21 | KaNDy Therapeutics Limited | New chemical process for making 6-chloro-4-(4-fluoro-2-methylphenyl)pyridin-3-amine a key intermediate of nt-814 |
| WO2025242585A1 (en) | 2024-05-24 | 2025-11-27 | Bayer Consumer Care Ag | Crystalline forms of salts of elinzanetant and compositions containing salts of elinzanetant |
| WO2025242583A1 (en) | 2024-05-24 | 2025-11-27 | Bayer Consumer Care Ag | Novel formulation comprising elinzanetant in a solid dispersion |
| US12533358B1 (en) | 2025-05-14 | 2026-01-27 | Bayer Consumer Care Ag | Methods of treatment with elinzanetant |
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| EP0912174B1 (en) | 1996-07-17 | 2004-04-28 | MERCK & CO., INC. | Alteration of circadian rhythmicity with non-peptidal neurikinin-1 receptor antagonists |
| EP1035115B1 (en) | 1999-02-24 | 2004-09-29 | F. Hoffmann-La Roche Ag | 4-Phenylpyridine derivatives and their use as NK-1 receptor antagonists |
| AU7788500A (en) | 1999-10-25 | 2001-05-08 | Janssen Pharmaceutica N.V. | Use of substance p antagonists for influencing the circadian timing system |
| GB0203020D0 (en) | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
| GB0203022D0 (en) | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
| TW200403058A (en) * | 2002-04-19 | 2004-03-01 | Bristol Myers Squibb Co | Heterocyclo inhibitors of potassium channel function |
| ES2291891T3 (es) * | 2003-07-03 | 2008-03-01 | F. Hoffmann-La Roche Ag | Antagonistas duales de nk1/nk3 para tratamiento de esquizofrenia. |
| DK1928886T3 (da) * | 2005-09-09 | 2011-07-11 | Glaxosmithkline Llc | Pyridin-derivater og deres anvendelse i behandlingen af psykotiske lidelser |
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2009
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- 2009-08-04 EA EA201170300A patent/EA201170300A1/ru unknown
- 2009-08-04 EP EP09781468A patent/EP2321324A1/en not_active Withdrawn
- 2009-08-04 KR KR1020117005159A patent/KR20110052686A/ko not_active Withdrawn
- 2009-08-04 CA CA2733235A patent/CA2733235A1/en not_active Abandoned
- 2009-08-04 AU AU2009279135A patent/AU2009279135B2/en not_active Ceased
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- 2009-08-04 BR BRPI0917224A patent/BRPI0917224A2/pt not_active IP Right Cessation
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- 2011-01-20 IL IL210777A patent/IL210777A0/en unknown
Also Published As
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| MX2011001414A (es) | 2011-04-04 |
| US8093242B2 (en) | 2012-01-10 |
| CN102171219A (zh) | 2011-08-31 |
| EP2321324A1 (en) | 2011-05-18 |
| AU2009279135B2 (en) | 2012-09-13 |
| AU2009279135A1 (en) | 2010-02-11 |
| GB0814340D0 (en) | 2008-09-10 |
| KR20110052686A (ko) | 2011-05-18 |
| ZA201100426B (en) | 2012-03-28 |
| US20110136798A1 (en) | 2011-06-09 |
| CA2733235A1 (en) | 2010-02-11 |
| BRPI0917224A2 (pt) | 2015-11-24 |
| EA201170300A1 (ru) | 2011-08-30 |
| IL210777A0 (en) | 2011-03-31 |
| WO2010015626A1 (en) | 2010-02-11 |
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