JP2011528709A - インクレチンおよびインクレチン模倣ペプチドの持続性送達用経皮システム - Google Patents
インクレチンおよびインクレチン模倣ペプチドの持続性送達用経皮システム Download PDFInfo
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- JP2011528709A JP2011528709A JP2011519280A JP2011519280A JP2011528709A JP 2011528709 A JP2011528709 A JP 2011528709A JP 2011519280 A JP2011519280 A JP 2011519280A JP 2011519280 A JP2011519280 A JP 2011519280A JP 2011528709 A JP2011528709 A JP 2011528709A
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- incretin
- exendin
- skin
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- transdermal patch
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- Epidemiology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Zoology (AREA)
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- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Electrotherapy Devices (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US8223208P | 2008-07-21 | 2008-07-21 | |
| US61/082,232 | 2008-07-21 | ||
| PCT/IL2009/000713 WO2010010555A2 (en) | 2008-07-21 | 2009-07-21 | Transdermal system for extended delivery of incretins and incretin mimetic peptides |
Publications (2)
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| JP2011528709A true JP2011528709A (ja) | 2011-11-24 |
| JP2011528709A5 JP2011528709A5 (enExample) | 2012-08-16 |
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| US (1) | US20110129522A1 (enExample) |
| EP (1) | EP2303247A4 (enExample) |
| JP (1) | JP2011528709A (enExample) |
| CA (1) | CA2731236A1 (enExample) |
| WO (1) | WO2010010555A2 (enExample) |
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| US8357150B2 (en) | 2009-07-20 | 2013-01-22 | Syneron Medical Ltd. | Method and apparatus for fractional skin treatment |
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| HUE035803T2 (en) | 2012-12-21 | 2018-05-28 | Sanofi Sa | Dual GLP1 / GIP or trigonal GLP1 / GIP / glucagon agonists |
| WO2015086730A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Non-acylated exendin-4 peptide analogues |
| TW201609797A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重ｇｌｐ－１／升糖素受體促效劑 |
| WO2015086728A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
| EP3080154B1 (en) | 2013-12-13 | 2018-02-07 | Sanofi | Dual glp-1/gip receptor agonists |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑 |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| TW201706291A (zh) | 2015-07-10 | 2017-02-16 | 賽諾菲公司 | 作為選擇性肽雙重ｇｌｐ－１／升糖素受體促效劑之新毒蜥外泌肽（ｅｘｅｎｄｉｎ－４）衍生物 |
| US11105815B2 (en) | 2018-04-26 | 2021-08-31 | University Of Kentucky Research Foundation | Compositions and methods for enhancing neuro-repair |
Citations (2)
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| JP2007513939A (ja) * | 2003-12-09 | 2007-05-31 | トランスファーマ メディカル リミテッド | ポリペプチドの持続性送達用経皮システム |
| JP2008517055A (ja) * | 2004-10-19 | 2008-05-22 | 日東電工株式会社 | インクレチンホルモン活性を持つペプチドの経上皮送達 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5766620A (en) * | 1995-10-23 | 1998-06-16 | Theratech, Inc. | Buccal delivery of glucagon-like insulinotropic peptides |
| DE69740096D1 (de) * | 1996-08-08 | 2011-02-17 | Amylin Pharmaceuticals Inc | Pharmazeutische Zusammensetzung mit einem Exendin-4-Peptid |
| JP4798814B2 (ja) * | 1997-01-07 | 2011-10-19 | アミリン・ファーマシューティカルズ，インコーポレイテッド | 食物摂取低減用のエキセンジンおよびそのアゴニストの使用 |
| US6344180B1 (en) * | 1999-06-15 | 2002-02-05 | Bionebraska, Inc. | GLP-1 as a diagnostic test to determine β-cell function and the presence of the condition of IGT and type II diabetes |
| US7198801B2 (en) * | 2000-08-03 | 2007-04-03 | Antares Pharma Ipl Ag | Formulations for transdermal or transmucosal application |
| EP1750754A4 (en) * | 2004-03-31 | 2010-09-22 | Centocor Ortho Biotech Inc | HUMAN GLP-1 MIMETIC BODIES, COMPOSITIONS, METHODS AND USES |
| WO2006062422A1 (en) * | 2004-12-10 | 2006-06-15 | Protemix Corporation Limited | Glyponectin (glycosylated adiponectin) for the treatment of diseases and conditions |
| CN102088935B (zh) * | 2008-03-31 | 2015-07-15 | 日东电工株式会社 | 透膜物递送系统 |
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- 2009-07-21 EP EP09800150A patent/EP2303247A4/en not_active Withdrawn
- 2009-07-21 CA CA2731236A patent/CA2731236A1/en not_active Abandoned
- 2009-07-21 JP JP2011519280A patent/JP2011528709A/ja active Pending
- 2009-07-21 US US13/054,908 patent/US20110129522A1/en not_active Abandoned
- 2009-07-21 WO PCT/IL2009/000713 patent/WO2010010555A2/en not_active Ceased
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007513939A (ja) * | 2003-12-09 | 2007-05-31 | トランスファーマ メディカル リミテッド | ポリペプチドの持続性送達用経皮システム |
| JP2008517055A (ja) * | 2004-10-19 | 2008-05-22 | 日東電工株式会社 | インクレチンホルモン活性を持つペプチドの経上皮送達 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010010555A2 (en) | 2010-01-28 |
| US20110129522A1 (en) | 2011-06-02 |
| EP2303247A2 (en) | 2011-04-06 |
| WO2010010555A8 (en) | 2011-03-24 |
| EP2303247A4 (en) | 2012-08-01 |
| CA2731236A1 (en) | 2010-01-28 |
| WO2010010555A3 (en) | 2010-05-20 |
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