JP2011528007A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011528007A5 JP2011528007A5 JP2011517863A JP2011517863A JP2011528007A5 JP 2011528007 A5 JP2011528007 A5 JP 2011528007A5 JP 2011517863 A JP2011517863 A JP 2011517863A JP 2011517863 A JP2011517863 A JP 2011517863A JP 2011528007 A5 JP2011528007 A5 JP 2011528007A5
- Authority
- JP
- Japan
- Prior art keywords
- dione
- trifluoromethyl
- triazine
- group
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0854794A FR2933979B1 (fr) | 2008-07-15 | 2008-07-15 | Derives de triazines et uraciles, leur preparation et leur application en therapeutique humaine |
| FR0854794 | 2008-07-15 | ||
| PCT/EP2009/058609 WO2010006962A1 (en) | 2008-07-15 | 2009-07-07 | Derivatives of triazines and uracils, their preparation and their application in human therapeutics |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011528007A JP2011528007A (ja) | 2011-11-10 |
| JP2011528007A5 true JP2011528007A5 (https=) | 2012-08-30 |
| JP5599788B2 JP5599788B2 (ja) | 2014-10-01 |
Family
ID=40394394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011517863A Expired - Fee Related JP5599788B2 (ja) | 2008-07-15 | 2009-07-07 | トリアジンおよびウラシルの誘導体、それらの調製、およびヒト治療薬におけるそれらの応用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8618287B2 (https=) |
| EP (1) | EP2328886B1 (https=) |
| JP (1) | JP5599788B2 (https=) |
| AR (1) | AR072510A1 (https=) |
| FR (1) | FR2933979B1 (https=) |
| TW (1) | TW201006815A (https=) |
| WO (1) | WO2010006962A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102791701B (zh) | 2009-12-30 | 2014-02-12 | 深圳信立泰药业股份有限公司 | 作为二肽基肽酶iv(dpp-iv)抑制剂的3-(3-氨基哌啶-1-基)-5-氧代-1,2,4-三嗪衍生物 |
| FR2958935B1 (fr) * | 2010-04-19 | 2012-06-22 | Pf Medicament | Derives d'heterocycles azotes, leur preparation et leur application en therapeutique humaine |
| CN104803971B (zh) * | 2014-01-24 | 2021-11-30 | 深圳信立泰药业股份有限公司 | 化合物A单苯甲酸盐的晶型α及其制备方法和含有该晶型的药物组合物 |
| CN105017213B (zh) * | 2014-04-30 | 2017-11-14 | 成都苑东生物制药股份有限公司 | 尿嘧啶衍生物 |
| CN107074823B (zh) | 2014-09-05 | 2021-05-04 | 基因泰克公司 | 治疗性化合物及其用途 |
| JP2019533022A (ja) | 2016-10-24 | 2019-11-14 | ユマニティ セラピューティクス，インコーポレーテッド | 化合物及びその使用 |
| EP3566055B1 (en) | 2017-01-06 | 2025-03-12 | Janssen Pharmaceutica NV | Scd inhibitor for the treatment of neurological disorders |
| CA3083000A1 (en) | 2017-10-24 | 2019-05-02 | Yumanity Therapeutics, Inc. | Compounds and uses thereof |
| WO2019183587A1 (en) | 2018-03-23 | 2019-09-26 | Yumanity Therapeutics, Inc. | Compounds and uses thereof |
| TWI884745B (zh) * | 2018-10-12 | 2025-05-21 | 美商拓臻股份有限公司 | 甲狀腺素受體β促效劑化合物 |
| CN111320609A (zh) | 2018-12-13 | 2020-06-23 | 拓臻股份有限公司 | 一种THRβ受体激动剂化合物及其制备方法和用途 |
| WO2020154571A1 (en) | 2019-01-24 | 2020-07-30 | Yumanity Therapeutics, Inc. | Compounds and uses thereof |
| AU2020336272A1 (en) | 2019-08-23 | 2022-04-14 | Terns Pharmaceuticals, Inc. | Thyroid hormone receptor beta agonist compounds |
| WO2021050945A1 (en) | 2019-09-12 | 2021-03-18 | Terns, Inc. | Thyroid hormone receptor beta agonist compounds |
| EA202192047A1 (ru) | 2019-11-13 | 2021-12-08 | Юманити Терапьютикс, Инк. | Соединения и их применение |
| WO2021104288A1 (zh) | 2019-11-26 | 2021-06-03 | 昆药集团股份有限公司 | 1，2，4-三嗪-3，5-二酮类化合物及其制备方法和应用 |
| WO2024102455A1 (en) * | 2022-11-09 | 2024-05-16 | Emory University | Non-covalent inhibitors of coronavirus main protease |
| EP4568664B1 (en) | 2023-04-07 | 2026-04-01 | Terns Pharmaceuticals, Inc. | Combination comprising a thr-beta agonist and a glp-1r agonist for use in treating obesity |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5973573A (ja) * | 1982-09-09 | 1984-04-25 | ワ−ナ−−ランバ−ト・コンパニ− | ジアミノピリミジン化合物 |
| WO2004033427A1 (en) * | 2002-10-11 | 2004-04-22 | Astrazeneca Ab | 1,4-disubstituted piperidine derivatives and their use as 11-betahsd1 inhibitors |
| FR2866339B1 (fr) * | 2004-02-18 | 2006-05-05 | Pf Medicament | Derives de 1,2,4-triazines, leur preparation et leur application en therapeutique humaine |
| TW200609219A (en) * | 2004-06-17 | 2006-03-16 | Neurogen Corp | Aryl-substituted piperazine derivatives |
| EP1966183A4 (en) * | 2005-12-20 | 2010-12-29 | Merck Frosst Canada Ltd | HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A-DELTA-9-DESATURASE |
-
2008
- 2008-07-15 FR FR0854794A patent/FR2933979B1/fr not_active Expired - Fee Related
-
2009
- 2009-07-07 US US13/054,293 patent/US8618287B2/en not_active Expired - Fee Related
- 2009-07-07 EP EP09797466.1A patent/EP2328886B1/en not_active Not-in-force
- 2009-07-07 WO PCT/EP2009/058609 patent/WO2010006962A1/en not_active Ceased
- 2009-07-07 JP JP2011517863A patent/JP5599788B2/ja not_active Expired - Fee Related
- 2009-07-10 TW TW098123438A patent/TW201006815A/zh unknown
- 2009-07-15 AR ARP090102680A patent/AR072510A1/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011528007A5 (https=) | ||
| TW502025B (en) | Pyridazine derivatives having inhibitory activity against interleukin-1β production and pharmaceutical composition containing the same | |
| JP5426544B2 (ja) | ピリミジニル−ピリダジノン誘導体 | |
| CN100502863C (zh) | 2,4,5-三取代噻唑衍生物和它们的抗炎活性 | |
| CN1152867C (zh) | 作为药物的喹唑啉衍生物 | |
| JP2008513514A5 (https=) | ||
| AU2018282336A1 (en) | Trk-inhibiting compound | |
| JP2007500715A5 (https=) | ||
| DE102008062826A1 (de) | Pyridazinonderivate | |
| US6469018B1 (en) | Compounds | |
| CN112638876B (zh) | 用于治疗rna病毒感染的苯基/吡啶基-n-苯基/吡啶基衍生物 | |
| CZ20004339A3 (cs) | Nové 2-alkylem substituované imidazolové sloučeniny | |
| WO2003037891A1 (en) | Heteroaryl amines as glycogen synthase kinase 3beta inhibitors (gsk3 inhibitors) | |
| JP2972377B2 (ja) | カテコール誘導体、その薬学的に許容しうる塩およびエステルならびにそれらを含有する医薬組成物 | |
| AU2002363176A1 (en) | Heteroaryl amines as glycogen synthase kinase 3Beta inhibitors (GSK3 inhibitors) | |
| WO2010017870A1 (de) | Bicyclische triazolderivate zur behandlung von tumoren | |
| WO2002047690A1 (en) | Substituted 2-aryl-4-arylaminopyrimidines and analogs as activators of caspases and inducers of apoptosis and the use thereof | |
| JP2012525431A5 (https=) | ||
| WO2008145243A1 (de) | Pyridazinonderivate | |
| DE102008019907A1 (de) | Pyridazinonderivate | |
| JP2010516701A5 (https=) | ||
| JP2010516700A5 (https=) | ||
| JP2011528007A (ja) | トリアジンおよびウラシルの誘導体、それらの調製、およびヒト治療薬におけるそれらの応用 | |
| JP2012529513A (ja) | トリアジン誘導体類及びそれらの治療応用 | |
| WO2007070506B1 (en) | Diaza heterocyclic sulfonamide derivatives and their uses |