JP2011527694A5 - - Google Patents
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- Publication number
- JP2011527694A5 JP2011527694A5 JP2011517599A JP2011517599A JP2011527694A5 JP 2011527694 A5 JP2011527694 A5 JP 2011527694A5 JP 2011517599 A JP2011517599 A JP 2011517599A JP 2011517599 A JP2011517599 A JP 2011517599A JP 2011527694 A5 JP2011527694 A5 JP 2011527694A5
- Authority
- JP
- Japan
- Prior art keywords
- cyclosporin
- group
- compound
- iminoalkylthio
- sar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13451008P | 2008-07-10 | 2008-07-10 | |
| US61/134,510 | 2008-07-10 | ||
| PCT/US2009/050038 WO2010006117A2 (en) | 2008-07-10 | 2009-07-09 | Cyclosporin derivatives for treating ocular and dermal diseases and conditions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011527694A JP2011527694A (ja) | 2011-11-04 |
| JP2011527694A5 true JP2011527694A5 (https=) | 2012-08-23 |
| JP5661035B2 JP5661035B2 (ja) | 2015-01-28 |
Family
ID=41404608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011517599A Expired - Fee Related JP5661035B2 (ja) | 2008-07-10 | 2009-07-09 | 眼および皮膚の疾患および症状の治療用のシクロスポリン誘導体 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8716238B2 (https=) |
| EP (1) | EP2313157A2 (https=) |
| JP (1) | JP5661035B2 (https=) |
| KR (1) | KR20110031973A (https=) |
| CN (1) | CN102149402B (https=) |
| AU (1) | AU2009268549B2 (https=) |
| BR (1) | BRPI0915552A2 (https=) |
| CA (1) | CA2730108A1 (https=) |
| RU (2) | RU2521358C2 (https=) |
| WO (1) | WO2010006117A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20110031973A (ko) * | 2008-07-10 | 2011-03-29 | 알러간, 인코포레이티드 | 눈 및 피부의 질환 및 상태를 치료하기 위한 사이클로스포린 유도체 |
| WO2010138422A1 (en) * | 2009-05-27 | 2010-12-02 | Allergan, Inc. | Cyclosporin derivatives for enhancing the growth of hair |
| WO2010138423A1 (en) * | 2009-05-27 | 2010-12-02 | Allergan, Inc. | Cyclosporin derivatives for treating inflammatory diseases and conditions |
| MX2013004062A (es) | 2010-10-12 | 2013-07-22 | Allergan Inc | Analogos de ciclosporina. |
| BR112013008864A2 (pt) | 2010-10-12 | 2016-06-28 | Allergan Inc | análogos d ciclosporina |
| WO2012079172A1 (en) * | 2010-12-15 | 2012-06-21 | Isotechnika Pharma Inc. | Cyclosporine analogue molecules modified at amino acid 1 and 3 |
| RU2630970C2 (ru) * | 2011-11-15 | 2017-09-15 | Аллерган, Инк. | Автоклавируемые взвеси циклоспорина а формы 2 |
| JP2015519368A (ja) | 2012-06-01 | 2015-07-09 | アラーガン インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | シクロスポリンａ類似体 |
| WO2014138425A1 (en) | 2013-03-08 | 2014-09-12 | Allergan, Inc. | Cyclosporine a-steroid conjugates |
| US9463201B2 (en) | 2014-10-19 | 2016-10-11 | M.G. Therapeutics Ltd | Compositions and methods for the treatment of meibomian gland dysfunction |
| US9914755B2 (en) | 2015-01-08 | 2018-03-13 | Allergan, Inc. | Cyclosporin derivatives wherein the MeBmt sidechain has been cyclized |
| ES3007759T3 (en) | 2015-09-28 | 2025-03-20 | Azura Ophthalmics Ltd | Thiol and disulfide-containing agents for increasing meibomian gland lipid secretion |
| CN114469991A (zh) | 2016-04-14 | 2022-05-13 | 阿祖拉眼科有限公司 | 用于治疗睑板腺功能障碍的二硫化硒组合物 |
| CA3166357A1 (en) | 2020-01-10 | 2021-07-15 | Azura Ophthalmics Ltd. | Instructions for composition and sensitivity |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4649047A (en) | 1985-03-19 | 1987-03-10 | University Of Georgia Research Foundation, Inc. | Ophthalmic treatment by topical administration of cyclosporin |
| US5474979A (en) | 1994-05-17 | 1995-12-12 | Allergan, Inc. | Nonirritating emulsions for sensitive tissue |
| FR2757520B1 (fr) | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Derive de cyclosporine, sa preparation et les compositions pharmaceutiques qui le contiennent |
| FR2757522B1 (fr) | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2757521B1 (fr) | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| PT1086124E (pt) | 1998-06-12 | 2004-04-30 | Chem Ag C | Ciclosporinas novas |
| US6254860B1 (en) * | 1999-04-13 | 2001-07-03 | Allergan Sales, Inc. | Ocular treatment using cyclosporin-A derivatives |
| US6806279B2 (en) | 2001-12-17 | 2004-10-19 | Sunesis Pharmaceuticals, Inc. | Small-molecule inhibitors of interleukin-2 |
| KR20030065831A (ko) * | 2002-02-01 | 2003-08-09 | 주식회사 태평양 | 사이클로스포린을 함유한 지속 방출형 약학적 조성물 |
| KR20110031973A (ko) * | 2008-07-10 | 2011-03-29 | 알러간, 인코포레이티드 | 눈 및 피부의 질환 및 상태를 치료하기 위한 사이클로스포린 유도체 |
-
2009
- 2009-07-09 KR KR1020117003044A patent/KR20110031973A/ko not_active Ceased
- 2009-07-09 WO PCT/US2009/050038 patent/WO2010006117A2/en not_active Ceased
- 2009-07-09 CN CN200980135354.4A patent/CN102149402B/zh not_active Expired - Fee Related
- 2009-07-09 RU RU2011104584/15A patent/RU2521358C2/ru not_active IP Right Cessation
- 2009-07-09 AU AU2009268549A patent/AU2009268549B2/en not_active Expired - Fee Related
- 2009-07-09 JP JP2011517599A patent/JP5661035B2/ja not_active Expired - Fee Related
- 2009-07-09 US US12/499,911 patent/US8716238B2/en active Active
- 2009-07-09 BR BRPI0915552A patent/BRPI0915552A2/pt not_active IP Right Cessation
- 2009-07-09 EP EP09790191A patent/EP2313157A2/en not_active Withdrawn
- 2009-07-09 CA CA2730108A patent/CA2730108A1/en not_active Abandoned
-
2014
- 2014-01-15 RU RU2014101057/15A patent/RU2014101057A/ru not_active Application Discontinuation
- 2014-03-17 US US14/215,794 patent/US20140200185A1/en not_active Abandoned
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