JP2011527575A5 - - Google Patents
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- Publication number
- JP2011527575A5 JP2011527575A5 JP2011517443A JP2011517443A JP2011527575A5 JP 2011527575 A5 JP2011527575 A5 JP 2011527575A5 JP 2011517443 A JP2011517443 A JP 2011517443A JP 2011517443 A JP2011517443 A JP 2011517443A JP 2011527575 A5 JP2011527575 A5 JP 2011527575A5
- Authority
- JP
- Japan
- Prior art keywords
- gene expression
- level
- tumor
- heyl
- cancer tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8012208P | 2008-07-11 | 2008-07-11 | |
| US61/080,122 | 2008-07-11 | ||
| US12/360,790 | 2009-01-27 | ||
| US12/360,790 US7544476B1 (en) | 2008-07-11 | 2009-01-27 | Identifying cancers sensitive to treatment with inhibitors of notch signaling |
| PCT/US2009/045479 WO2010005644A1 (en) | 2008-07-11 | 2009-05-28 | Identifying cancers sensitive to treatment with inhibitors of notch signaling |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011527575A JP2011527575A (ja) | 2011-11-04 |
| JP2011527575A5 true JP2011527575A5 (https=) | 2012-07-12 |
Family
ID=40688675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011517443A Pending JP2011527575A (ja) | 2008-07-11 | 2009-05-28 | Ｎｏｔｃｈシグナル伝達のインヒビターでの処置に感受性であるがんの同定 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7544476B1 (https=) |
| EP (1) | EP2313526A4 (https=) |
| JP (1) | JP2011527575A (https=) |
| AU (1) | AU2009269081A1 (https=) |
| CA (1) | CA2730215A1 (https=) |
| WO (1) | WO2010005644A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007136856A2 (en) * | 2006-05-19 | 2007-11-29 | The Johns Hopkins University | Heyl as a therapeutic target and a diagnostic marker for neoplasia and uses therefor |
| JP5386364B2 (ja) | 2006-12-18 | 2014-01-15 | ジェネンテック， インコーポレイテッド | 抗Ｎｏｔｃｈ３アンタゴニスト抗体とＮｏｔｃｈ３関連疾患の予防及び治療におけるその使用 |
| US20120082659A1 (en) * | 2007-10-02 | 2012-04-05 | Hartmut Land | Methods And Compositions Related To Synergistic Responses To Oncogenic Mutations |
| WO2014100435A1 (en) | 2012-12-19 | 2014-06-26 | Aveo Pharmaceuticals, Inc. | Anti-notch3 antibodies |
| DK3448420T3 (da) | 2016-04-29 | 2022-12-12 | Aveo Pharmaceuticals Inc | Anti-notch3-antistof |
| EP3462349A1 (en) * | 2017-10-02 | 2019-04-03 | Koninklijke Philips N.V. | Assessment of notch cellular signaling pathway activity using mathematical modelling of target gene expression |
| EP3502279A1 (en) | 2017-12-20 | 2019-06-26 | Koninklijke Philips N.V. | Assessment of mapk-ap 1 cellular signaling pathway activity using mathematical modelling of target gene expression |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006047878A1 (en) | 2004-11-03 | 2006-05-11 | British Columbia Cancer Agency Branch | Cancer therapeutics and methods for their use |
| US20080206753A1 (en) | 2005-03-04 | 2008-08-28 | The Hospital For Sick Children | Methods for Cancer Prognosis |
| DK1962895T3 (da) * | 2005-12-16 | 2013-03-04 | Regeneron Pharma | TERAPEUTISK ANVENDELSE AF EN Dll4-ANTAGONIST OG EN VEGF-HÆMMER TIL HÆMNING AF TUMORVÆKST |
| WO2007136856A2 (en) | 2006-05-19 | 2007-11-29 | The Johns Hopkins University | Heyl as a therapeutic target and a diagnostic marker for neoplasia and uses therefor |
-
2009
- 2009-01-27 US US12/360,790 patent/US7544476B1/en not_active Expired - Fee Related
- 2009-05-28 WO PCT/US2009/045479 patent/WO2010005644A1/en not_active Ceased
- 2009-05-28 JP JP2011517443A patent/JP2011527575A/ja active Pending
- 2009-05-28 EP EP09794862A patent/EP2313526A4/en not_active Withdrawn
- 2009-05-28 CA CA2730215A patent/CA2730215A1/en not_active Abandoned
- 2009-05-28 AU AU2009269081A patent/AU2009269081A1/en not_active Abandoned
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