JP2011525388A5 - - Google Patents
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- Publication number
- JP2011525388A5 JP2011525388A5 JP2011514898A JP2011514898A JP2011525388A5 JP 2011525388 A5 JP2011525388 A5 JP 2011525388A5 JP 2011514898 A JP2011514898 A JP 2011514898A JP 2011514898 A JP2011514898 A JP 2011514898A JP 2011525388 A5 JP2011525388 A5 JP 2011525388A5
- Authority
- JP
- Japan
- Prior art keywords
- delivery system
- eye
- latanoprost
- punctal plug
- days
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 25
- GGXICVAJURFBLW-CEYXHVGTSA-N latanoprost Chemical compound CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CC[C@@H](O)CCC1=CC=CC=C1 GGXICVAJURFBLW-CEYXHVGTSA-N 0.000 claims 21
- 229960001160 latanoprost Drugs 0.000 claims 21
- 230000004410 intraocular pressure Effects 0.000 claims 11
- 241000083513 Punctum Species 0.000 claims 10
- 238000013268 sustained release Methods 0.000 claims 9
- 239000012730 sustained-release form Substances 0.000 claims 9
- 239000003814 drug Substances 0.000 claims 7
- 208000010412 Glaucoma Diseases 0.000 claims 6
- 239000003889 eye drop Substances 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 229940079593 drug Drugs 0.000 claims 3
- 238000009472 formulation Methods 0.000 claims 3
- 150000003180 prostaglandins Chemical class 0.000 claims 3
- 229920002988 biodegradable polymer Polymers 0.000 claims 2
- 239000004621 biodegradable polymer Substances 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 239000013589 supplement Substances 0.000 claims 2
- UCTWMZQNUQWSLP-VIFPVBQESA-N (R)-adrenaline Chemical class CNC[C@H](O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-VIFPVBQESA-N 0.000 claims 1
- 201000002862 Angle-Closure Glaucoma Diseases 0.000 claims 1
- 206010030348 Open-Angle Glaucoma Diseases 0.000 claims 1
- 239000000695 adrenergic alpha-agonist Substances 0.000 claims 1
- 229940006133 antiglaucoma drug and miotics carbonic anhydrase inhibitors Drugs 0.000 claims 1
- 239000002876 beta blocker Substances 0.000 claims 1
- 229940097320 beta blocking agent Drugs 0.000 claims 1
- 239000003489 carbonate dehydratase inhibitor Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000006196 drop Substances 0.000 claims 1
- 230000004406 elevated intraocular pressure Effects 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000003547 miosis Effects 0.000 claims 1
- 239000003604 miotic agent Substances 0.000 claims 1
- 229920001296 polysiloxane Polymers 0.000 claims 1
- 201000006366 primary open angle glaucoma Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7528408P | 2008-06-24 | 2008-06-24 | |
| US61/075,284 | 2008-06-24 | ||
| PCT/US2009/048452 WO2010008883A1 (en) | 2008-06-24 | 2009-06-24 | Combination treatment of glaucoma |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011525388A JP2011525388A (ja) | 2011-09-22 |
| JP2011525388A5 true JP2011525388A5 (https=) | 2012-08-02 |
Family
ID=41431875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011514898A Pending JP2011525388A (ja) | 2008-06-24 | 2009-06-24 | 緑内障の併用治療 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20090318549A1 (https=) |
| EP (1) | EP2303184A4 (https=) |
| JP (1) | JP2011525388A (https=) |
| CN (1) | CN102105118A (https=) |
| CA (1) | CA2728623A1 (https=) |
| TW (1) | TW201012469A (https=) |
| WO (1) | WO2010008883A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1765454T3 (en) | 2004-07-02 | 2016-05-02 | Mati Therapeutics Inc | Device for submission of treatment medium to eye |
| EP2004172B1 (en) | 2006-03-31 | 2019-03-13 | Mati Therapeutics Inc. | Drug delivery structures and compositions for nasolacrimal system |
| NZ583858A (en) | 2007-09-07 | 2012-08-31 | Quadra Logic Tech Inc | Lacrimal implant detection with detection device |
| CN102123713A (zh) * | 2008-05-09 | 2011-07-13 | Qlt栓塞输送公司 | 治疗青光眼和眼高血压的活性剂的持续释放递送 |
| EP2437684B1 (en) | 2009-06-03 | 2022-06-15 | ForSight Vision5, Inc. | Anterior segment drug delivery |
| US10272040B2 (en) | 2010-08-12 | 2019-04-30 | Nanyang Technological University | Liposomal formulation for ocular drug delivery |
| US8591484B2 (en) | 2010-09-15 | 2013-11-26 | AlphaMed, Inc. | Lacrimal punctum measurement and occlusion |
| US20120312840A1 (en) * | 2011-05-13 | 2012-12-13 | Ayako Hasegawa | Container closure system with integral antimicrobial additives |
| ES2727203T3 (es) | 2011-08-29 | 2019-10-14 | Mati Therapeutics Inc | Administración por liberación sostenida de agentes activos para tratar glaucoma e hipertensión ocular |
| US9974685B2 (en) | 2011-08-29 | 2018-05-22 | Mati Therapeutics | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension |
| EP2755615B1 (en) | 2011-09-14 | 2022-04-06 | Forsight Vision5, Inc. | Ocular insert apparatus |
| DK2911623T3 (da) | 2012-10-26 | 2019-10-28 | Forsight Vision5 Inc | Oftalmisk system til langvarig frigivelse af lægemiddel til øjet |
| US20140206708A1 (en) * | 2013-01-24 | 2014-07-24 | Rigel Pharmaceuticals, Inc. | Composition for ophthalmic administration |
| US9956195B2 (en) | 2014-01-07 | 2018-05-01 | Nanyang Technological University | Stable liposomal formulations for ocular drug delivery |
| US9424722B2 (en) * | 2014-05-14 | 2016-08-23 | Unlimited Liability, LLC | Smart memory material lock devices |
| JP6555758B2 (ja) * | 2014-09-22 | 2019-08-07 | 株式会社カネカ | 内視鏡用注射器具 |
| WO2016083891A1 (en) * | 2014-11-25 | 2016-06-02 | Eyal Sheetrit | Compositions and methods for delivering a bio-active agent or bio-active agents |
| US20160296532A1 (en) | 2015-04-13 | 2016-10-13 | Forsight Vision5, Inc. | Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent |
| US11291847B2 (en) * | 2015-06-16 | 2022-04-05 | The Regents Of The University Of Colorado, A Body Corporate | Systems and methods for preventing, diagnosing, and/or treating one or more medical conditions via neuromodulation |
| CN105879126A (zh) * | 2016-03-24 | 2016-08-24 | 杭州亚慧生物科技有限公司 | 一种超润滑血清白蛋白泪点塞及其制备方法 |
| EP3773330B1 (en) * | 2018-03-29 | 2025-03-05 | Mati Therapeutics Inc. | Ophthalmic drug sustained release formulation and uses for dry eye syndrome treatment |
| CN109568138B (zh) * | 2019-01-10 | 2021-06-25 | 新疆国际旅行卫生保健中心 | 药片分割装置 |
| US12447045B2 (en) | 2019-10-02 | 2025-10-21 | Segal Innovations LLC | Bio-adhesive dissolving compounds and device |
| US11207267B2 (en) | 2019-10-02 | 2021-12-28 | Segal Innovations LLC | Bio-adhesive dissolving compounds and device |
| US12023276B2 (en) | 2021-02-24 | 2024-07-02 | Ocular Therapeutix, Inc. | Intracanalicular depot inserter device |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4281654A (en) * | 1980-04-07 | 1981-08-04 | Alza Corporation | Drug delivery system for controlled ocular therapy |
| US5589563A (en) * | 1992-04-24 | 1996-12-31 | The Polymer Technology Group | Surface-modifying endgroups for biomedical polymers |
| CA2134087C (en) * | 1992-04-24 | 2007-07-17 | Robert S. Ward | Copolymers and non-porous, semi-permeable membrane thereof and its use for permeating molecules of predetermined molecular weight range |
| US6196993B1 (en) * | 1998-04-20 | 2001-03-06 | Eyelab Group, Llc | Ophthalmic insert and method for sustained release of medication to the eye |
| ES2172415B2 (es) * | 2000-07-28 | 2003-11-16 | Univ Madrid Complutense | Tratamiento del glaucoma y la hipertension ocular por medio de un analogo de la melatonina. |
| US6534693B2 (en) * | 2000-11-06 | 2003-03-18 | Afmedica, Inc. | Surgically implanted devices having reduced scar tissue formation |
| CA2513751C (en) * | 2003-01-24 | 2012-01-10 | Control Delivery Systems, Inc. | Sustained release device and method for ocular delivery of adrenergic agents |
| EP1603485A4 (en) * | 2003-02-26 | 2011-03-30 | Medivas Llc | BIOACTIVE STENTS AND METHOD OF USE THEREOF |
| US7662864B2 (en) * | 2003-06-04 | 2010-02-16 | Rutgers, The State University Of New Jersey | Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent |
| US20050129731A1 (en) * | 2003-11-03 | 2005-06-16 | Roland Horres | Biocompatible, biostable coating of medical surfaces |
| US20050232972A1 (en) * | 2004-04-15 | 2005-10-20 | Steven Odrich | Drug delivery via punctal plug |
| US7799336B2 (en) * | 2004-04-30 | 2010-09-21 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
| WO2007047744A2 (en) * | 2005-10-14 | 2007-04-26 | Alcon, Inc. | Method for treating primary and secondary forms of glaucoma |
| EP2004172B1 (en) * | 2006-03-31 | 2019-03-13 | Mati Therapeutics Inc. | Drug delivery structures and compositions for nasolacrimal system |
| MX2009006146A (es) * | 2006-12-18 | 2009-06-19 | Alcon Res Ltd | Dispositivos y metodos para la administracion de farmacos oftalmicos. |
| UY30883A1 (es) * | 2007-01-31 | 2008-05-31 | Alcon Res | Tapones punctales y metodos de liberacion de agentes terapeuticos |
| AU2008300013A1 (en) * | 2007-09-07 | 2009-03-19 | Qlt Inc. | Drug cores for sustained release of therapeutic agents |
| CN102670352A (zh) * | 2007-09-07 | 2012-09-19 | Qlt股份有限公司 | 用于泪腺植入物的插入和抽出工具 |
| CA2698508C (en) * | 2007-09-07 | 2017-06-06 | Alan R. Rapacki | Lacrimal implants and related methods |
| SG188155A1 (en) * | 2008-02-18 | 2013-03-28 | Quadra Logic Tech Inc | Lacrimal implants and related methods |
| WO2009134371A2 (en) * | 2008-04-30 | 2009-11-05 | Qlt Plug Delivery, Inc. | Composite lacrimal insert and related methods |
| CN102123713A (zh) * | 2008-05-09 | 2011-07-13 | Qlt栓塞输送公司 | 治疗青光眼和眼高血压的活性剂的持续释放递送 |
-
2009
- 2009-06-24 EP EP09798519.6A patent/EP2303184A4/en not_active Withdrawn
- 2009-06-24 WO PCT/US2009/048452 patent/WO2010008883A1/en not_active Ceased
- 2009-06-24 US US12/490,923 patent/US20090318549A1/en not_active Abandoned
- 2009-06-24 JP JP2011514898A patent/JP2011525388A/ja active Pending
- 2009-06-24 TW TW098121236A patent/TW201012469A/zh unknown
- 2009-06-24 CN CN2009801288704A patent/CN102105118A/zh active Pending
- 2009-06-24 CA CA2728623A patent/CA2728623A1/en not_active Abandoned
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