JP2011523662A - 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト - Google Patents
胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト Download PDFInfo
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Landscapes
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| JP2016532697A (ja) * | 2013-08-09 | 2016-10-20 | アーデリクス，インコーポレーテッド | リン酸塩輸送阻害のための化合物及び方法 |
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| WO2002078683A1 (en) | 2001-03-29 | 2002-10-10 | Synergy Pharmaceuticals, Inc. | Guanylate cyclase receptor agonists for the treatment of tissue inflammation and carcinogenesis |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| WO2008151257A2 (en) | 2007-06-04 | 2008-12-11 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| ES2627848T3 (es) | 2008-06-04 | 2017-07-31 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
| ES2559840T3 (es) | 2008-06-04 | 2016-02-16 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
| ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
| JP5964589B2 (ja) * | 2008-12-03 | 2016-08-03 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼｃアゴニストの製剤およびその使用方法 |
| US9301991B2 (en) | 2009-05-30 | 2016-04-05 | The University Of Toledo | sGCalphal inhibiting compositions |
| WO2010141349A1 (en) | 2009-05-30 | 2010-12-09 | University Of Toledo | Soluble guanylyl cyclase a1 and a-8r peptide as diagnostic markers of and therapeutic targets for prostate cancer |
| MY173390A (en) | 2009-10-23 | 2020-01-22 | Takeda Pharmaceuticals Co | Anti-gcc antibody molecules and related compositions and methods |
| AT509267A1 (de) * | 2010-01-14 | 2011-07-15 | Apeptico Forschung & Entwicklung Gmbh | Organische verbindungen zur regulierung von vektoriellen ionenkanälen |
| BR112012019666A2 (pt) * | 2010-02-05 | 2017-06-20 | Bayer Ip Gmbh | estimuladores da sgc ou ativadores da sgc individualmente e em combinação com inibidores da pde5 para o tratamento de fibrose cística |
| EP2621509A4 (en) | 2010-09-15 | 2016-08-03 | Synergy Pharmaceuticals Inc | FORMULATIONS OF GUANYLATE CYCLASE C AGONISTS AND METHOD OF USE |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| MX357121B (es) | 2011-03-01 | 2018-06-27 | Synergy Pharmaceuticals Inc Star | Proceso de preparacion de agonistas c de guanilato ciclasa. |
| HRP20191690T1 (hr) | 2012-04-27 | 2019-12-27 | Millennium Pharmaceuticals, Inc. | Molekule anti-gcc antitijela i njihova uporaba u ispitivanju osjetljivosti na gcc-ciljanu terapiju |
| EP2958577A2 (en) | 2013-02-25 | 2015-12-30 | Synergy Pharmaceuticals Inc. | Guanylate cyclase receptor agonists for use in colonic cleansing |
| EP2968439A2 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| PL3004138T3 (pl) | 2013-06-05 | 2024-07-29 | Bausch Health Ireland Limited | Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie |
| WO2015011086A1 (en) | 2013-07-25 | 2015-01-29 | Bayer Pharma Aktiengesellschaft | Sgc stimulators or sgc activators and pde5 inhibitors in combination with additional treatment for the therapy of cystic fibrosis |
| CA2926691A1 (en) * | 2013-10-10 | 2015-04-16 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of opioid induced dysfunctions |
| WO2015066285A2 (en) * | 2013-11-01 | 2015-05-07 | The University Of Toledo | sGCα1 INHIBITING COMPOSITIONS, AND METHODS OF TREATMENT OF CANCERS THEREWITH |
| EP3402804A1 (en) | 2016-01-11 | 2018-11-21 | Synergy Pharmaceuticals Inc. | Formulations and methods for treating ulcerative colitis |
| US20210393621A1 (en) | 2018-10-26 | 2021-12-23 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
| JP2022533251A (ja) | 2019-05-21 | 2022-07-21 | アルデリックス， インコーポレイテッド | 患者において血清リン酸塩を低下させるための組み合わせ |
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| US12569481B2 (en) | 2020-06-12 | 2026-03-10 | Vanderbilt University | Methods of treatment for gastrointestinal motility disorders |
| US12029718B2 (en) | 2021-11-09 | 2024-07-09 | Cct Sciences, Llc | Process for production of essentially pure delta-9-tetrahydrocannabinol |
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2009
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- 2009-06-04 US US12/478,505 patent/US8207295B2/en active Active
- 2009-06-04 CA CA2726913A patent/CA2726913C/en active Active
- 2009-06-04 WO PCT/US2009/046287 patent/WO2009149278A1/en not_active Ceased
- 2009-06-04 JP JP2011512657A patent/JP2011523662A/ja active Pending
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- 2009-06-04 EP EP09759437.8A patent/EP2296685B1/en active Active
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- 2012-05-09 US US13/467,703 patent/US8357775B2/en active Active
- 2012-12-17 US US13/716,874 patent/US8497348B2/en active Active
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2013
- 2013-06-27 US US13/928,830 patent/US20130274204A1/en not_active Abandoned
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016532697A (ja) * | 2013-08-09 | 2016-10-20 | アーデリクス，インコーポレーテッド | リン酸塩輸送阻害のための化合物及び方法 |
| JP2020063273A (ja) * | 2013-08-09 | 2020-04-23 | アーデリクス，インコーポレーテッド | リン酸塩輸送阻害のための化合物及び方法 |
| JP2022031687A (ja) * | 2013-08-09 | 2022-02-22 | アーデリクス，インコーポレーテッド | リン酸塩輸送阻害のための化合物及び方法 |
| JP7894693B2 (ja) | 2013-08-09 | 2026-07-24 | アーデリクス，インコーポレーテッド | リン酸塩輸送阻害のための化合物及び方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20120220526A1 (en) | 2012-08-30 |
| US20130274204A1 (en) | 2013-10-17 |
| EP2296685B1 (en) | 2015-09-02 |
| HK1155092A1 (zh) | 2012-05-11 |
| ES2559840T3 (es) | 2016-02-16 |
| WO2009149278A8 (en) | 2010-04-22 |
| WO2009149278A1 (en) | 2009-12-10 |
| US8357775B2 (en) | 2013-01-22 |
| CA2726913C (en) | 2020-02-25 |
| CA2726913A1 (en) | 2009-12-10 |
| US8497348B2 (en) | 2013-07-30 |
| AU2009256156A1 (en) | 2009-12-10 |
| AU2009256156B2 (en) | 2014-09-18 |
| US8207295B2 (en) | 2012-06-26 |
| US20130096071A1 (en) | 2013-04-18 |
| EP2296685A1 (en) | 2011-03-23 |
| US20100069306A1 (en) | 2010-03-18 |
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