JP2011523659A5 - - Google Patents

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Publication number
JP2011523659A5
JP2011523659A5 JP2011512196A JP2011512196A JP2011523659A5 JP 2011523659 A5 JP2011523659 A5 JP 2011523659A5 JP 2011512196 A JP2011512196 A JP 2011512196A JP 2011512196 A JP2011512196 A JP 2011512196A JP 2011523659 A5 JP2011523659 A5 JP 2011523659A5
Authority
JP
Japan
Prior art keywords
compound
formula
solvent
base
levocetirizine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011512196A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011523659A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB2009/001385 external-priority patent/WO2009147389A2/en
Publication of JP2011523659A publication Critical patent/JP2011523659A/ja
Publication of JP2011523659A5 publication Critical patent/JP2011523659A5/ja
Pending legal-status Critical Current

Links

JP2011512196A 2008-06-02 2009-06-02 レボセチリジンの合成方法及びそれに使用する中間体 Pending JP2011523659A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1173MU2008 2008-06-02
IN1173/MUM/2008 2008-06-02
PCT/GB2009/001385 WO2009147389A2 (en) 2008-06-02 2009-06-02 Processes for the synthesis of levocetirizine and intermediates for use therein

Publications (2)

Publication Number Publication Date
JP2011523659A JP2011523659A (ja) 2011-08-18
JP2011523659A5 true JP2011523659A5 (https=) 2012-07-19

Family

ID=41009315

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011512196A Pending JP2011523659A (ja) 2008-06-02 2009-06-02 レボセチリジンの合成方法及びそれに使用する中間体

Country Status (10)

Country Link
US (1) US8350031B2 (https=)
EP (1) EP2307392A2 (https=)
JP (1) JP2011523659A (https=)
KR (1) KR20110022635A (https=)
CN (1) CN102046612A (https=)
AU (1) AU2009254959B2 (https=)
CA (1) CA2724887A1 (https=)
NZ (1) NZ589492A (https=)
WO (1) WO2009147389A2 (https=)
ZA (1) ZA201008223B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110022635A (ko) 2008-06-02 2011-03-07 시플라 리미티드 레보세티리진의 합성방법 및 이에 사용하기 위한 중간체
CN103044356A (zh) * 2011-10-13 2013-04-17 湖南九典制药有限公司 合成左西替利嗪的新方法及其关键中间体
CN110988163B (zh) * 2019-11-29 2022-04-19 重庆华邦胜凯制药有限公司 一种hplc法分离测定盐酸左西替利嗪及其基因毒性杂质e的方法
CN111205247B (zh) * 2020-04-22 2020-08-14 湖南九典宏阳制药有限公司 左旋西替利嗪的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2792398A (en) * 1954-12-03 1957-05-14 Miles Lab Piperazine derivatives
US3790606A (en) * 1970-09-30 1974-02-05 Diamond Shamrock Corp Alkoxylated mannich compositions and derivatives thereof
NL7306771A (https=) * 1972-06-02 1973-12-04
DK154078C (da) 1981-02-06 1989-05-22 Ucb Sa Analogifremgangsmaade til fremstilling af 2-(2-(4-(diphenyl-methyl)-1-piperazinyl)ethoxy)-acetamider eller syreadditionssalte heraf
US4656182A (en) 1983-12-06 1987-04-07 Warner-Lambert Company Substituted trans-1,2-diaminocyclohexyl amide compounds
GB8827391D0 (en) 1988-11-23 1988-12-29 Ucb Sa Process for preparation of 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-pipera-zinyl)ethoxy)-acetic acid & its dihydrochloride
GB9305282D0 (en) * 1993-03-15 1993-05-05 Ucb Sa Enantiomers of 1-(4-chlorophenyl)phenylmethyl)-4-(4-methylphenyl)sulphonyl)piperazine
JP4416198B2 (ja) * 1997-12-19 2010-02-17 武田薬品工業株式会社 アニリド誘導体、その製造法および用途
BR0007784A (pt) * 1999-01-27 2002-02-05 American Cyanamid Co Composto, método para inibir mudanças patológicas mediadas pela enzima que converte o tnf-alfa (tace) em um mamìfero, composição farmacêutica, e, processo para preparar um composto
AR035312A1 (es) * 1999-01-27 2004-05-12 Wyeth Corp Compuestos de acido hidroxamico que contienen alquinilo como inhibidores de metaloproteinasa de matriz/tace, composicion farmaceutica que los comprenden y el uso de los mismos para la manufactura de un medicamento
US6762180B1 (en) * 1999-10-13 2004-07-13 Boehringer Ingelheim Pharma Kg Substituted indolines which inhibit receptor tyrosine kinases
JP4044740B2 (ja) * 2001-05-31 2008-02-06 信越化学工業株式会社 レジスト材料及びパターン形成方法
HU227074B1 (en) 2005-12-08 2010-06-28 Egis Gyogyszergyar Nyrt An optically active carbamic acid derivative, method for producing the same and use as a pharmaceutical intermediate
KR20110022635A (ko) 2008-06-02 2011-03-07 시플라 리미티드 레보세티리진의 합성방법 및 이에 사용하기 위한 중간체

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