JP2011523405A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011523405A5 JP2011523405A5 JP2011508703A JP2011508703A JP2011523405A5 JP 2011523405 A5 JP2011523405 A5 JP 2011523405A5 JP 2011508703 A JP2011508703 A JP 2011508703A JP 2011508703 A JP2011508703 A JP 2011508703A JP 2011523405 A5 JP2011523405 A5 JP 2011523405A5
- Authority
- JP
- Japan
- Prior art keywords
- igf
- variable domain
- drug
- immunoglobulin variable
- chain immunoglobulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940079593 drug Drugs 0.000 claims 17
- 239000003814 drug Substances 0.000 claims 17
- 108060003951 Immunoglobulin Proteins 0.000 claims 15
- 102000018358 immunoglobulin Human genes 0.000 claims 15
- 108090001117 Insulin-Like Growth Factor II Proteins 0.000 claims 12
- 102000048143 Insulin-Like Growth Factor II Human genes 0.000 claims 12
- 102000004169 proteins and genes Human genes 0.000 claims 11
- 108090000623 proteins and genes Proteins 0.000 claims 11
- 102000023732 binding proteins Human genes 0.000 claims 8
- 108091008324 binding proteins Proteins 0.000 claims 8
- 125000003275 alpha amino acid group Chemical group 0.000 claims 7
- 108010051696 Growth Hormone Proteins 0.000 claims 6
- 102000018997 Growth Hormone Human genes 0.000 claims 6
- 239000000122 growth hormone Substances 0.000 claims 6
- 230000009001 hormonal pathway Effects 0.000 claims 6
- 102000038461 Growth Hormone-Releasing Hormone Human genes 0.000 claims 5
- 239000000095 Growth Hormone-Releasing Hormone Substances 0.000 claims 5
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 101710142969 Somatoliberin Proteins 0.000 claims 5
- 201000011510 cancer Diseases 0.000 claims 4
- 108091035707 Consensus sequence Proteins 0.000 claims 2
- 229940124013 Growth hormone receptor antagonist Drugs 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 206010071051 Soft tissue mass Diseases 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 102000006395 Globulins Human genes 0.000 claims 1
- 108010044091 Globulins Proteins 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000005556 hormone Substances 0.000 claims 1
- 229940088597 hormone Drugs 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 238000002649 immunization Methods 0.000 claims 1
- 230000003902 lesion Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 108700037519 pegvisomant Proteins 0.000 claims 1
- 239000003488 releasing hormone Substances 0.000 claims 1
- 229940099077 somavert Drugs 0.000 claims 1
- 230000006641 stabilisation Effects 0.000 claims 1
- 238000011105 stabilization Methods 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5195608P | 2008-05-09 | 2008-05-09 | |
| US61/051,956 | 2008-05-09 | ||
| US5342708P | 2008-05-15 | 2008-05-15 | |
| US61/053,427 | 2008-05-15 | ||
| US16318009P | 2009-03-25 | 2009-03-25 | |
| US61/163,180 | 2009-03-25 | ||
| PCT/US2009/043273 WO2009137758A2 (en) | 2008-05-09 | 2009-05-08 | Igf-ii/gf-iie binding proteins |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014016462A Division JP2014077020A (ja) | 2008-05-09 | 2014-01-31 | Ｉｇｆ−ｉｉ／ｉｇｆ−ｉｉｅ結合タンパク質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011523405A JP2011523405A (ja) | 2011-08-11 |
| JP2011523405A5 true JP2011523405A5 (OSRAM) | 2013-04-11 |
| JP5734180B2 JP5734180B2 (ja) | 2015-06-17 |
Family
ID=41265434
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011508703A Expired - Fee Related JP5734180B2 (ja) | 2008-05-09 | 2009-05-08 | Ｉｇｆ−ｉｉ／ｉｇｆ−ｉｉｅ結合タンパク質 |
| JP2014016462A Pending JP2014077020A (ja) | 2008-05-09 | 2014-01-31 | Ｉｇｆ−ｉｉ／ｉｇｆ−ｉｉｅ結合タンパク質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014016462A Pending JP2014077020A (ja) | 2008-05-09 | 2014-01-31 | Ｉｇｆ−ｉｉ／ｉｇｆ−ｉｉｅ結合タンパク質 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20110165145A1 (OSRAM) |
| EP (1) | EP2296703A4 (OSRAM) |
| JP (2) | JP5734180B2 (OSRAM) |
| AU (1) | AU2009244091B2 (OSRAM) |
| CA (1) | CA2723722A1 (OSRAM) |
| WO (1) | WO2009137758A2 (OSRAM) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20090368A1 (es) | 2007-06-19 | 2009-04-28 | Boehringer Ingelheim Int | Anticuerpos anti-igf |
| WO2010045315A1 (en) * | 2008-10-14 | 2010-04-22 | Dyax Corp. | Use of igf-ii/igf-iie binding for the treatment and prevention of systemic sclerosis associated pulmonary fibrosis |
| EP2376116B1 (en) | 2008-12-12 | 2015-12-09 | Boehringer Ingelheim International GmbH | Anti-igf antibodies |
| US9150644B2 (en) | 2011-04-12 | 2015-10-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II |
| US20140255413A1 (en) | 2013-03-07 | 2014-09-11 | Boehringer Ingelheim International Gmbh | Combination therapy for neoplasia treatment |
| KR101843248B1 (ko) * | 2015-03-17 | 2018-03-29 | 고려대학교 세종산학협력단 | 흉선 기질 림프단백질 매개 신호전달을 제어하는 펩타이드 유도체 및 이를 포함하는 알러지 및 천식 질환 예방 및 치료용 약학 조성물 |
| US10469309B1 (en) * | 2016-04-28 | 2019-11-05 | Servicenow, Inc. | Management of computing system alerts |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2058041A1 (en) * | 1990-06-27 | 1991-12-28 | Katsuichi Sakano | Anti-igf-ii monoclonal antibody |
| JP3213359B2 (ja) * | 1990-12-21 | 2001-10-02 | 第一製薬株式会社 | 抗ｉｇｆ−ｉｉモノクローナル抗体 |
| US7438911B2 (en) * | 2002-04-30 | 2008-10-21 | Kyowa Hakko Kogyo Co., Ltd. | Antibody against human insulin-like growth factor |
| WO2005018671A1 (ja) * | 2003-08-21 | 2005-03-03 | Kyowa Hakko Kogyo Co., Ltd. | 癌転移阻害剤 |
| WO2005028515A1 (ja) * | 2003-09-24 | 2005-03-31 | Kyowa Hakko Kogyo Co., Ltd. | ヒトインスリン様成長因子に対する遺伝子組換え抗体 |
| JPWO2005027970A1 (ja) * | 2003-09-24 | 2007-11-15 | 協和醗酵工業株式会社 | 癌治療用医薬 |
| US7612179B2 (en) * | 2003-11-28 | 2009-11-03 | Astrazeneca Ab | antibodies binding to a C-terminal fragment of apoliopoprotein E |
| AU2005215024B2 (en) * | 2004-02-19 | 2011-07-21 | Dyax Corp. | Conformation specific antibodies |
| JP2008515774A (ja) * | 2004-08-03 | 2008-05-15 | ダイアックス コーポレイション | ｈＫ１結合タンパク質 |
| WO2007022172A1 (en) * | 2005-08-17 | 2007-02-22 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Human monoclonal antibodies that specifically bind igf-ii |
| ATE552853T1 (de) * | 2005-12-13 | 2012-04-15 | Medimmune Ltd | Proteine die spezifisch insulin-ähnliche wachstumsfaktoren binden, und deren anwendungen |
| US8071323B2 (en) * | 2006-04-07 | 2011-12-06 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Human monoclonal antibodies that bind human insulin like growth factors and their use |
| US8178091B2 (en) * | 2007-05-21 | 2012-05-15 | University Of Washington | Compositions and methods for the treatment of respiratory disorders |
-
2009
- 2009-05-08 JP JP2011508703A patent/JP5734180B2/ja not_active Expired - Fee Related
- 2009-05-08 EP EP09743744A patent/EP2296703A4/en not_active Withdrawn
- 2009-05-08 CA CA2723722A patent/CA2723722A1/en not_active Abandoned
- 2009-05-08 AU AU2009244091A patent/AU2009244091B2/en not_active Ceased
- 2009-05-08 US US12/991,691 patent/US20110165145A1/en not_active Abandoned
- 2009-05-08 WO PCT/US2009/043273 patent/WO2009137758A2/en not_active Ceased
-
2014
- 2014-01-31 JP JP2014016462A patent/JP2014077020A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023061927A5 (OSRAM) | ||
| TWI354561B (en) | Pharmaceutical compositions and uses for treatment | |
| JP2019523295A5 (OSRAM) | ||
| RU2421464C2 (ru) | Человеческие антитела к il-13 и их терапевтическое применение | |
| JP2004532817A5 (OSRAM) | ||
| TW201206478A (en) | Multiple-variable dose regimen for treating TNF α -related disorders | |
| JP2015508063A5 (OSRAM) | ||
| JP2012100677A5 (OSRAM) | ||
| JP2005533001A5 (OSRAM) | ||
| JP2010526028A5 (OSRAM) | ||
| JP2016501839A5 (OSRAM) | ||
| JP2018529634A5 (OSRAM) | ||
| JP2011518886A5 (OSRAM) | ||
| JP2018502120A5 (OSRAM) | ||
| RU2012156938A (ru) | Антитела против gdf8 человека | |
| JP2016509585A5 (OSRAM) | ||
| JP2006516116A5 (OSRAM) | ||
| JP2018500924A5 (OSRAM) | ||
| NO20083793L (no) | Antistoffer mot amyloid-beta peptid | |
| CN105358175B (zh) | 用于治疗硬皮病的抗ccl2和抗loxl2组合疗法 | |
| SI3064511T1 (en) | THE MEDICINE USE OF HUMAN HIGHLIGHTS FOR HUMAN RECEPTOR IL-4 | |
| RU2014105496A (ru) | Способы снижения числа эозинофилов | |
| JP2022523740A (ja) | Ｒｏｒ１抗体イムノコンジュゲートによる癌の治療 | |
| JP2009539841A5 (OSRAM) | ||
| RU2018100129A (ru) | Способы лечения подагры |