JP2011520986A5 - - Google Patents
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- Publication number
- JP2011520986A5 JP2011520986A5 JP2011510736A JP2011510736A JP2011520986A5 JP 2011520986 A5 JP2011520986 A5 JP 2011520986A5 JP 2011510736 A JP2011510736 A JP 2011510736A JP 2011510736 A JP2011510736 A JP 2011510736A JP 2011520986 A5 JP2011520986 A5 JP 2011520986A5
- Authority
- JP
- Japan
- Prior art keywords
- alkylene
- triazolo
- quinolin
- ethyl
- pyridin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 0 C*(c1c[n]cn1)=C Chemical compound C*(c1c[n]cn1)=C 0.000 description 5
- BYGSCHNVKNYURN-UHFFFAOYSA-N CC(C)C(C#CC)NC=C=C Chemical compound CC(C)C(C#CC)NC=C=C BYGSCHNVKNYURN-UHFFFAOYSA-N 0.000 description 1
- HJTMVZBMPGRPEZ-UHFFFAOYSA-N CS(C=C)c1n[nH]cc1 Chemical compound CS(C=C)c1n[nH]cc1 HJTMVZBMPGRPEZ-UHFFFAOYSA-N 0.000 description 1
- AYTGARGOCPEHGL-UHFFFAOYSA-N Cc1ccc2OCCOc2c1 Chemical compound Cc1ccc2OCCOc2c1 AYTGARGOCPEHGL-UHFFFAOYSA-N 0.000 description 1
- PQHJOXAAUHYVKJ-UHFFFAOYSA-N Ic1c[nH]cc1 Chemical compound Ic1c[nH]cc1 PQHJOXAAUHYVKJ-UHFFFAOYSA-N 0.000 description 1
- NSMRXHVDVYBQSF-UHFFFAOYSA-N Sc1c2OCCOc2ccc1 Chemical compound Sc1c2OCCOc2ccc1 NSMRXHVDVYBQSF-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12855508P | 2008-05-22 | 2008-05-22 | |
| US61/128,555 | 2008-05-22 | ||
| PCT/US2009/045058 WO2009143477A1 (en) | 2008-05-22 | 2009-05-22 | Heterocycles as protein kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011520986A JP2011520986A (ja) | 2011-07-21 |
| JP2011520986A5 true JP2011520986A5 (https=) | 2013-05-23 |
Family
ID=40998185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011510736A Ceased JP2011520986A (ja) | 2008-05-22 | 2009-05-22 | タンパク質キナーゼ阻害薬としての複素環類 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8691838B2 (https=) |
| EP (1) | EP2310389B1 (https=) |
| JP (1) | JP2011520986A (https=) |
| AT (1) | ATE540038T1 (https=) |
| AU (1) | AU2009248839B2 (https=) |
| CA (1) | CA2724715A1 (https=) |
| ES (1) | ES2376404T3 (https=) |
| MX (1) | MX2010012528A (https=) |
| WO (1) | WO2009143477A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3795573B1 (en) | 2009-12-31 | 2022-07-06 | Hutchison Medipharma Limited | Certain triazolopyrazines, compositions thereof and methods of use therefor |
| US20140107151A1 (en) * | 2011-05-17 | 2014-04-17 | Principia Biophama Inc. | Tyrosine kinase inhibitors |
| ME03455B (me) | 2012-09-10 | 2020-01-20 | Principia Biopharma Inc | Jedinjenja pirazolopirimidina kao inhibitori kinaze |
| PT3107544T (pt) | 2014-02-21 | 2021-01-05 | Principia Biopharma Inc | Sais e forma sólida de um inibidor de btk |
| US10485797B2 (en) | 2014-12-18 | 2019-11-26 | Principia Biopharma Inc. | Treatment of pemphigus |
| TW201718572A (zh) | 2015-06-24 | 2017-06-01 | 普林斯匹亞生物製藥公司 | 酪胺酸激酶抑制劑 |
| CA2994027C (en) | 2015-07-31 | 2023-10-10 | Merck Patent Gmbh | Bicyclic heterocyclic derivatives |
| MA45547A (fr) | 2016-06-29 | 2019-05-08 | Principia Biopharma Inc | Formulations à libération modifiée à base de 2-[3-[4-amino-3-(2-fluoro-4-phénoxy-phényl)pyrazolo[3,4-d]pyrimidine-1-yl]pipéridine-1-carbonyl]-4-méthyl-4-[4-(oxétane-3-yl)pipérazine-1-yl]pent-2-ènenitrile |
| TWI877239B (zh) | 2019-10-14 | 2025-03-21 | 美商普林斯匹亞生物製藥公司 | 藉由投予(R)-2-[3-[4-胺基-3-(2-氟-4-苯氧基-苯基)吡唑并[3,4-d]嘧啶-1-基]哌啶-1-羰基]-4-甲基-4-[4-(氧呾-3-基)哌-1-基]戊-2-烯腈來治療免疫血小板減少症之方法 |
| JP2023511105A (ja) | 2020-01-22 | 2023-03-16 | プリンシピア バイオファーマ インコーポレイテッド | ２－［３－［４－アミノ－３－（２－フルオロ－４－フェノキシ－フェニル）－１ｈ－ピラゾロ［３，４－ｄ］ピリミジン－１－イル］ピペリジン－１－カルボニル］－４－メチル－４－［４－（オキセタン－３－イル）ピペラジン－１－イル］ペンタ－２－エンニトリルの結晶形態 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4405619A (en) | 1981-09-02 | 1983-09-20 | Diamond Shamrock Corporation | Antiinflammatory substituted-1,2,4-triazolo[4,3-b]-1,2,4-triazines |
| ZA857647B (en) | 1984-10-12 | 1986-05-28 | Warner Lambert Co | Purine derivatives |
| US4772606A (en) * | 1985-08-22 | 1988-09-20 | Warner-Lambert Company | Purine derivatives |
| DE4110019C2 (de) | 1991-03-27 | 2000-04-13 | Merck Patent Gmbh | Imidazopyridine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
| US5798364A (en) | 1992-03-26 | 1998-08-25 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Imidazopyridines |
| US20050096322A1 (en) | 2002-03-01 | 2005-05-05 | Susumu Igarashi | Nitrogen-containing heterocyclic compound |
| DE10238477A1 (de) | 2002-08-22 | 2004-03-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Purinderivate, deren Herstellung und deren Verwendung als Arzneimittel |
| AU2003271064B2 (en) * | 2002-09-27 | 2010-06-17 | Dainippon Sumitomo Pharma Co., Ltd. | Novel adenine compound and use thereof |
| UY28103A1 (es) | 2002-12-03 | 2004-06-30 | Boehringer Ingelheim Pharma | Nuevas imidazo-piridinonas sustituidas, su preparación y su empleo como medicacmentos |
| US7109192B2 (en) * | 2002-12-03 | 2006-09-19 | Boehringer Ingelheim Pharma Gmbh & Co Kg | Substituted imidazo-pyridinones and imidazo-pyridazinones, the preparation thereof and their use as pharmaceutical compositions |
| US7250212B2 (en) | 2003-05-29 | 2007-07-31 | Nichias Corporation | Porous body-coated fiber, porous body-coated particle, and formed article using the same |
| BRPI0412003A (pt) | 2003-07-02 | 2006-08-15 | Sugen Inc | arilmetil triazol e imidazopirazinas como inibidores de c-met |
| US7122548B2 (en) | 2003-07-02 | 2006-10-17 | Sugen, Inc. | Triazolotriazine compounds and uses thereof |
| PE20080403A1 (es) * | 2006-07-14 | 2008-04-25 | Amgen Inc | Derivados heterociclicos fusionados y metodos de uso |
| DE102007026341A1 (de) | 2007-06-06 | 2008-12-11 | Merck Patent Gmbh | Benzoxazolonderivate |
-
2009
- 2009-05-22 EP EP09751705A patent/EP2310389B1/en active Active
- 2009-05-22 AT AT09751705T patent/ATE540038T1/de active
- 2009-05-22 JP JP2011510736A patent/JP2011520986A/ja not_active Ceased
- 2009-05-22 MX MX2010012528A patent/MX2010012528A/es active IP Right Grant
- 2009-05-22 AU AU2009248839A patent/AU2009248839B2/en not_active Ceased
- 2009-05-22 CA CA2724715A patent/CA2724715A1/en not_active Abandoned
- 2009-05-22 ES ES09751705T patent/ES2376404T3/es active Active
- 2009-05-22 WO PCT/US2009/045058 patent/WO2009143477A1/en not_active Ceased
- 2009-05-22 US US12/994,068 patent/US8691838B2/en active Active
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