JP2011520916A5 - - Google Patents
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- JP2011520916A5 JP2011520916A5 JP2011509763A JP2011509763A JP2011520916A5 JP 2011520916 A5 JP2011520916 A5 JP 2011520916A5 JP 2011509763 A JP2011509763 A JP 2011509763A JP 2011509763 A JP2011509763 A JP 2011509763A JP 2011520916 A5 JP2011520916 A5 JP 2011520916A5
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- Japan
- Prior art keywords
- pharmaceutical composition
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 15
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 230000007774 longterm Effects 0.000 claims 4
- 206010039085 Rhinitis allergic Diseases 0.000 claims 2
- 201000010105 allergic rhinitis Diseases 0.000 claims 2
- 108090000695 Cytokines Proteins 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090000174 Interleukin-10 Proteins 0.000 claims 1
- 108090000176 Interleukin-13 Proteins 0.000 claims 1
- 108090000978 Interleukin-4 Proteins 0.000 claims 1
- 108010002616 Interleukin-5 Proteins 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 210000003979 eosinophil Anatomy 0.000 claims 1
- 230000002519 immonomodulatory effect Effects 0.000 claims 1
- 230000009545 invasion Effects 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 239000002157 polynucleotide Substances 0.000 claims 1
- 102000040430 polynucleotide Human genes 0.000 claims 1
- 108091033319 polynucleotide Proteins 0.000 claims 1
- 210000002345 respiratory system Anatomy 0.000 claims 1
- 230000003442 weekly effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5360508P | 2008-05-15 | 2008-05-15 | |
| US61/053,605 | 2008-05-15 | ||
| PCT/US2009/044192 WO2009140626A2 (en) | 2008-05-15 | 2009-05-15 | Long term disease modification using immunostimulatory oligonucleotides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011520916A JP2011520916A (ja) | 2011-07-21 |
| JP2011520916A5 true JP2011520916A5 (cg-RX-API-DMAC10.html) | 2012-06-28 |
| JP5727367B2 JP5727367B2 (ja) | 2015-06-03 |
Family
ID=41258402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011509763A Active JP5727367B2 (ja) | 2008-05-15 | 2009-05-15 | 免疫賦活オリゴヌクレオチドを使用する長期疾患改良 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8815817B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2300102B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP5727367B2 (cg-RX-API-DMAC10.html) |
| AU (1) | AU2009246169B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2724418A1 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2009140626A2 (cg-RX-API-DMAC10.html) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100985457B1 (ko) * | 2001-06-21 | 2010-10-06 | 다이나박스 테크놀로지 코퍼레이션 | 키메라 면역조절 화합물 및 그것들의 사용 방법 |
| KR20070110901A (ko) * | 2005-03-04 | 2007-11-20 | 다이나박스 테크놀로지 코퍼레이션 | 항원에 콘쥬게이트되고 버퍼 조건 및 추가의 부형제들에의해 안정화된 면역자극성 서열(ｉｓｓ)을 갖는올리고뉴클레오티드를 포함하는 백신 |
| AU2009246169B2 (en) | 2008-05-15 | 2015-01-22 | Dynavax Technologies Corporation | Long term disease modification using immunostimulatory oligonucleotides |
| EP2451461A4 (en) | 2009-07-06 | 2013-05-29 | Ontorii Inc | NOVEL NUCLEIC ACID PRODRUGS AND METHOD OF USE THEREOF |
| DK2620428T3 (da) | 2010-09-24 | 2019-07-01 | Wave Life Sciences Ltd | Asymmetrisk hjælpegruppe |
| CN107320734A (zh) | 2011-04-29 | 2017-11-07 | 西莱克塔生物科技公司 | 从合成纳米载体中控制释放免疫抑制剂 |
| US10946568B2 (en) | 2011-06-09 | 2021-03-16 | Rimtec Corporation | Field joint coating material and a process for making a field joint |
| CN107365339A (zh) | 2011-07-19 | 2017-11-21 | 波涛生命科学有限公司 | 合成官能化核酸的方法 |
| JP5800263B2 (ja) * | 2011-09-27 | 2015-10-28 | 学校法人兵庫医科大学 | アレルギー性鼻炎治療剤のスクリーニング方法およびその利用 |
| WO2014010250A1 (en) | 2012-07-13 | 2014-01-16 | Chiralgen, Ltd. | Asymmetric auxiliary group |
| CN105307641A (zh) | 2013-05-03 | 2016-02-03 | 西莱克塔生物科技公司 | 用于降低不期望体液免疫应答的给药组合 |
| WO2015108046A1 (ja) * | 2014-01-15 | 2015-07-23 | 株式会社新日本科学 | 抗アレルギー作用を有するキラル核酸アジュバンド及び抗アレルギー剤 |
| EA201790551A1 (ru) | 2014-09-07 | 2017-07-31 | Селекта Байосайенсиз, Инк. | Способы и композиции для ослабления иммунных ответов к пропускающему экзон вирусному трансферному вектору |
| US20180071394A1 (en) * | 2016-08-25 | 2018-03-15 | Selecta Biosciences, Inc. | Polyester polymer matrices for the delivery of allergens |
| EP4599848A3 (en) | 2017-03-11 | 2025-12-03 | Cartesian Therapeutics, Inc. | Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant |
| US12553041B2 (en) | 2019-06-04 | 2026-02-17 | Cartesian Therapeutics Inc. | Formulations and doses of pegylated uricase |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US4948882A (en) | 1983-02-22 | 1990-08-14 | Syngene, Inc. | Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis |
| US4650675A (en) | 1983-08-18 | 1987-03-17 | The Children's Medical Center Corporation | Oligonucleotide conjugates |
| US5118800A (en) | 1983-12-20 | 1992-06-02 | California Institute Of Technology | Oligonucleotides possessing a primary amino group in the terminal nucleotide |
| US5118802A (en) | 1983-12-20 | 1992-06-02 | California Institute Of Technology | DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside |
| US4849513A (en) | 1983-12-20 | 1989-07-18 | California Institute Of Technology | Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups |
| US5015733A (en) | 1983-12-20 | 1991-05-14 | California Institute Of Technology | Nucleosides possessing blocked aliphatic amino groups |
| US4910300A (en) | 1985-12-11 | 1990-03-20 | Chiron Corporation | Method for making nucleic acid probes |
| US5093232A (en) | 1985-12-11 | 1992-03-03 | Chiron Corporation | Nucleic acid probes |
| US5124246A (en) | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| US5278302A (en) | 1988-05-26 | 1994-01-11 | University Patents, Inc. | Polynucleotide phosphorodithioates |
| US5391723A (en) | 1989-05-31 | 1995-02-21 | Neorx Corporation | Oligonucleotide conjugates |
| US5552391A (en) | 1990-01-16 | 1996-09-03 | La Jolla Pharmaceutical Company | Chemically-defined non-polymeric valency platform molecules and conjugates thereof |
| US5460831A (en) | 1990-06-22 | 1995-10-24 | The Regents Of The University Of California | Targeted transfection nanoparticles |
| AU713040B2 (en) | 1994-07-15 | 1999-11-18 | University Of Iowa Research Foundation, The | Immunomodulatory oligonucleotides |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| CA2244946C (en) | 1996-01-30 | 2010-04-13 | The Regents Of The University Of California | Gene expression vectors which generate an antigen specific immune response and methods of using the same |
| WO1998016247A1 (en) | 1996-10-11 | 1998-04-23 | The Regents Of The University Of California | Immunostimulatory polynucleotide/immunomodulatory molecule conjugates |
| WO1998055609A1 (en) | 1997-06-06 | 1998-12-10 | The Regents Of The University Of California | Inhibitors of dna immunostimulatory sequence activity |
| US6589940B1 (en) | 1997-06-06 | 2003-07-08 | Dynavax Technologies Corporation | Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof |
| PT1009413E (pt) * | 1997-09-05 | 2007-05-31 | Univ California | Utilização de oligonucleótidos imumoestimulantes para a prevenção ou tratamento da asma. |
| US6562798B1 (en) | 1998-06-05 | 2003-05-13 | Dynavax Technologies Corp. | Immunostimulatory oligonucleotides with modified bases and methods of use thereof |
| SE9901257D0 (sv) | 1999-04-09 | 1999-04-09 | Hel Ab | Behandling av smärta efter ledoperation |
| EP1176966B1 (en) | 1999-04-12 | 2013-04-03 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Oligodeoxynucleotide and its use to induce an immune response |
| US7585847B2 (en) | 2000-02-03 | 2009-09-08 | Coley Pharmaceutical Group, Inc. | Immunostimulatory nucleic acids for the treatment of asthma and allergy |
| US20030129251A1 (en) * | 2000-03-10 | 2003-07-10 | Gary Van Nest | Biodegradable immunomodulatory formulations and methods for use thereof |
| US20010046967A1 (en) * | 2000-03-10 | 2001-11-29 | Gary Van Nest | Methods of preventing and treating respiratory viral infection using immunomodulatory polynucleotide |
| US20040132677A1 (en) | 2001-06-21 | 2004-07-08 | Fearon Karen L. | Chimeric immunomodulatory compounds and methods of using the same-IV |
| DE10230693A1 (de) | 2002-07-06 | 2004-01-22 | BSH Bosch und Siemens Hausgeräte GmbH | Kühl-oder Gefriergerät |
| US7884083B2 (en) | 2002-08-12 | 2011-02-08 | Dynavax Technologies Corporation | Immunomodulatory compositions, methods of making, and methods of use thereof |
| DK1992635T3 (da) | 2002-12-23 | 2012-03-05 | Dynavax Tech Corp | Oligonukleotider med immunstimulatorisk sekvens og fremgangsmåder til anvendelse af disse |
| KR20070110901A (ko) * | 2005-03-04 | 2007-11-20 | 다이나박스 테크놀로지 코퍼레이션 | 항원에 콘쥬게이트되고 버퍼 조건 및 추가의 부형제들에의해 안정화된 면역자극성 서열(ｉｓｓ)을 갖는올리고뉴클레오티드를 포함하는 백신 |
| WO2008073661A2 (en) | 2006-11-09 | 2008-06-19 | Dynavax Technologies Corporation | Long term disease modification using immunostimulatory oligonucleotides |
| CN101945666A (zh) * | 2007-12-19 | 2011-01-12 | Mivac发展股份公司 | 治疗自身免疫和过敏性疾病的组合物及方法 |
| AU2009246169B2 (en) | 2008-05-15 | 2015-01-22 | Dynavax Technologies Corporation | Long term disease modification using immunostimulatory oligonucleotides |
-
2009
- 2009-05-15 AU AU2009246169A patent/AU2009246169B2/en not_active Ceased
- 2009-05-15 EP EP09747707.9A patent/EP2300102B1/en not_active Ceased
- 2009-05-15 US US12/992,590 patent/US8815817B2/en not_active Expired - Fee Related
- 2009-05-15 WO PCT/US2009/044192 patent/WO2009140626A2/en not_active Ceased
- 2009-05-15 JP JP2011509763A patent/JP5727367B2/ja active Active
- 2009-05-15 CA CA2724418A patent/CA2724418A1/en not_active Abandoned
-
2014
- 2014-07-18 US US14/335,790 patent/US9333254B2/en not_active Expired - Fee Related
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