JP2011518311A - ナノセンサプラットフォームを使用および構築する方法 - Google Patents

ナノセンサプラットフォームを使用および構築する方法 Download PDF

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JP2011518311A
JP2011518311A JP2010528111A JP2010528111A JP2011518311A JP 2011518311 A JP2011518311 A JP 2011518311A JP 2010528111 A JP2010528111 A JP 2010528111A JP 2010528111 A JP2010528111 A JP 2010528111A JP 2011518311 A JP2011518311 A JP 2011518311A
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nanosensor
disease
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nanowires
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JP2011518311A5 (enExample
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チョンウー チョウ,
マーク イー. トンプソン,
リチャード ジェイムス コート,
史朗 石川
マルコ カレリ,
シャオ−カン チャン,
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ユニバーシティー オブ サザン カリフォルニア
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6825Nucleic acid detection involving sensors
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403Cells and electrode assemblies
    • G01N27/414Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4146Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS involving nanosized elements, e.g. nanotubes, nanowires
    • CCHEMISTRY; METALLURGY
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]

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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2010528111A 2007-10-01 2008-10-01 ナノセンサプラットフォームを使用および構築する方法 Ceased JP2011518311A (ja)

Applications Claiming Priority (5)

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US97677407P 2007-10-01 2007-10-01
US97678007P 2007-10-01 2007-10-01
US60/976,780 2007-10-01
US60/976,774 2007-10-01
PCT/US2008/078502 WO2009085356A2 (en) 2007-10-01 2008-10-01 Methods of using and constructing nanosensor platforms

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US (3) US20100260745A1 (enExample)
EP (2) EP2210093A4 (enExample)
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CA (3) CA2701401C (enExample)
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016021693A1 (ja) * 2014-08-08 2016-02-11 日本化薬株式会社 電界効果型トランジスタおよびそれを用いたセンサ
JP2018504612A (ja) * 2014-11-07 2018-02-15 プロテオセンス 検体を検出するためのデバイス、システム、及び方法

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5211790B2 (ja) * 2007-03-26 2013-06-12 住友化学株式会社 Dnaメチル化測定方法
EP2210093A4 (en) 2007-10-01 2012-12-05 Univ Southern California METHODS OF USING AND CONSTRUCTING NANOCAPTOR PLATFORMS
WO2013154750A1 (en) 2012-04-10 2013-10-17 The Trustees Of Columbia Unversity In The City Of New York Systems and methods for biological ion channel interfaces
US20100204062A1 (en) * 2008-11-07 2010-08-12 University Of Southern California Calibration methods for multiplexed sensor arrays
US20100256344A1 (en) * 2009-04-03 2010-10-07 University Of Southern California Surface modification of nanosensor platforms to increase sensitivity and reproducibility
WO2011017077A2 (en) * 2009-07-27 2011-02-10 Trustees Of Boston University Nanochannel-based sensor system with controlled sensitivity
GB201004147D0 (en) * 2010-03-12 2010-04-28 Dna Electronics Ltd Method and apparatus for sensing methylation
DE202010017796U1 (de) * 2010-09-22 2012-09-07 Actc-Anti Cirme Technology Corporations Gmbh Substanz zur gerichtsverwertbaren Markierung
CN102033089A (zh) * 2010-10-27 2011-04-27 清华大学 生物传感器,其封装结构及检测系统
EP3444600B1 (en) 2011-01-11 2020-05-13 The Trustees of Columbia University in the City of New York System and methods for single-molecule detection using nanotubes
US8450131B2 (en) * 2011-01-11 2013-05-28 Nanohmics, Inc. Imprinted semiconductor multiplex detection array
CN103380369B (zh) 2011-02-23 2016-12-28 纽约市哥伦比亚大学理事会 使用纳米孔进行单分子检测的系统和方法
US9599614B2 (en) 2011-03-14 2017-03-21 Yale University Calibration of nanostructure sensors
US20130201316A1 (en) 2012-01-09 2013-08-08 May Patents Ltd. System and method for server based control
WO2013158280A1 (en) 2012-04-20 2013-10-24 The Trustees Of Columbia University In The City Of New York Systems and methods for single-molecule nucleic-acid assay platforms
US10088477B2 (en) 2012-07-30 2018-10-02 The Regents Of The University Of California Biomolecular detection test strip design
CN104685069A (zh) 2012-08-17 2015-06-03 拜奥-奈穆斯公司 核酸分类
US10457978B2 (en) * 2012-08-17 2019-10-29 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Cyclopentane-peptide nucleic acids for qualitative and quantitative detection of nucleic acids
EP2735868B1 (en) * 2012-11-26 2015-11-25 University College Cork Nanowire electrode sensor
US9316612B2 (en) 2013-01-04 2016-04-19 Yale University Regenerative nanosensor devices
KR102056928B1 (ko) * 2013-01-16 2019-12-18 삼성디스플레이 주식회사 터치스크린 패널 및 그의 제조방법
US9435896B2 (en) * 2013-07-31 2016-09-06 Globalfoundries Inc. Radiation detector based on charged self-assembled monolayers on nanowire devices
DE102014016712B4 (de) * 2014-11-13 2022-12-01 Dräger Safety AG & Co. KGaA Transportables Chipmesssystem und Verfahren zum Betrieb eines transportablen Chipmesssystems
WO2016085911A1 (en) * 2014-11-26 2016-06-02 Washington University Bioplasmonic detection of biomarkers in body fluids using peptide recognition elements
WO2016122630A1 (en) 2015-01-30 2016-08-04 Hewlett-Packard Development Company, L.P. Signal transmission bandwidth allocation on a microfluidic chip
KR102338748B1 (ko) * 2015-04-21 2021-12-15 삼성디스플레이 주식회사 터치 스크린 패널 및 이의 제조 방법
US20170015699A1 (en) * 2015-07-15 2017-01-19 Orizhan Bioscience Limited Partially Neutral Single-Stranded Oligonucleotide
US20180356405A1 (en) * 2015-09-29 2018-12-13 Essenlix Corp. Method of Detecting an Analyte in a Sample
US10502725B2 (en) * 2015-10-13 2019-12-10 University Of Utah Research Foundation Ultra-low power digital chemical analyzers
US10502724B2 (en) 2015-10-13 2019-12-10 University Of Utah Research Foundation Ultra-low power digital chemical analyzers
CN115753941A (zh) * 2016-06-30 2023-03-07 格拉夫威尔科技公司 极性流体门控场效应器件
CN106483191B (zh) * 2016-10-27 2019-03-08 吉林大学 一种通过消除甜点效应提高质谱检测重复性的方法
US20200294401A1 (en) 2017-09-04 2020-09-17 Nng Software Developing And Commercial Llc. A Method and Apparatus for Collecting and Using Sensor Data from a Vehicle
CN109470679B (zh) * 2017-09-08 2021-04-23 清华大学 用于分子检测的分子载体
WO2019152820A1 (en) * 2018-02-02 2019-08-08 Fred Hutchinson Cancer Research Center Methods for treating facioscapulohumeral muscular dystrophy
WO2020035852A2 (en) 2018-08-14 2020-02-20 Neurotrigger Ltd. Method and apparatus for transcutaneous facial nerve stimulation and applications thereof
US10968098B2 (en) * 2018-10-02 2021-04-06 International Business Machines Corporation Selective functionalization of sensing surface with nanoscale spatial resolution
US11143584B2 (en) 2018-10-02 2021-10-12 International Business Machines Corporation Selective functionalization of sensing surface
US11290708B2 (en) 2019-02-19 2022-03-29 Edgy Bees Ltd. Estimating real-time delay of a video data stream
US11054384B1 (en) * 2019-12-23 2021-07-06 Nanodx, Inc. Sensor system and methods of making
CN111551607B (zh) * 2020-05-21 2023-05-16 福建医锦智能科技有限公司 用于检测的生物阵列及其检测方法
WO2023283031A2 (en) * 2021-06-15 2023-01-12 Richard Postrel Handheld device for early detection of disease, biological, chemical, and pathogenic agents
IL309988A (en) 2021-07-26 2024-03-01 Bright Data Ltd Emulation of a web browser in a dedicated relay unit
USD1069156S1 (en) 2023-04-10 2025-04-01 Becton, Dickinson And Company Dispensing device
CN119574893B (zh) * 2025-02-07 2025-08-26 首都医科大学宣武医院 一种同时检测细胞外囊泡表面多种膜蛋白的方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004515782A (ja) * 2000-12-11 2004-05-27 プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ ナノセンサ
JP2004294087A (ja) * 2003-03-25 2004-10-21 Japan Science & Technology Agency pチャンネル電界効果トランジスタ及びそれを用いたセンサ
JP2006505806A (ja) * 2002-11-08 2006-02-16 ナノミックス・インコーポレーテッド ナノチューブをベースとする生体分子の電子検知
WO2006024023A2 (en) * 2004-08-24 2006-03-02 Nanomix, Inc. Nanotube sensor devices for dna detection
JP2006222279A (ja) * 2005-02-10 2006-08-24 Japan Science & Technology Agency n型トランジスタ、n型トランジスタセンサ及びn型トランジスタ用チャネルの製造方法
JP2008082988A (ja) * 2006-09-28 2008-04-10 Hokkaido Univ 多段階増幅を利用した検出方法

Family Cites Families (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA739100B (en) * 1972-12-15 1974-10-30 Ici Ltd Pesticidal composition's and process
US5637716A (en) * 1993-07-30 1997-06-10 Eisai Co., Ltd. Processes for the preparation of hydroquinone and benzoquinone derivatives
US5897945A (en) 1996-02-26 1999-04-27 President And Fellows Of Harvard College Metal oxide nanorods
US6036774A (en) 1996-02-26 2000-03-14 President And Fellows Of Harvard College Method of producing metal oxide nanorods
CA2298980A1 (en) * 1997-07-28 1999-02-04 Fox Chase Cancer Center Novel gene encoding a dna repair endonuclease and methods of use thereof
US6346189B1 (en) * 1998-08-14 2002-02-12 The Board Of Trustees Of The Leland Stanford Junior University Carbon nanotube structures made using catalyst islands
JP2004500569A (ja) * 2000-02-25 2004-01-08 ルミネックス コーポレイション 多重アッセイ法のための内部標準および内部対照
AU2001252973A1 (en) * 2000-04-17 2001-10-30 Purdue Research Foundation Biosensor and related method
US9709559B2 (en) * 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US6709566B2 (en) * 2000-07-25 2004-03-23 The Regents Of The University Of California Method for shaping a nanotube and a nanotube shaped thereby
US7301199B2 (en) * 2000-08-22 2007-11-27 President And Fellows Of Harvard College Nanoscale wires and related devices
US20070128744A1 (en) * 2005-07-27 2007-06-07 Tour James M Self-assembly of molecules and nanotubes and/or nanowires in nanocell computing devices, and methods for programming same
US6723299B1 (en) 2001-05-17 2004-04-20 Zyvex Corporation System and method for manipulating nanotubes
US6706402B2 (en) 2001-07-25 2004-03-16 Nantero, Inc. Nanotube films and articles
JP2003144172A (ja) 2001-11-16 2003-05-20 Nisshinbo Ind Inc メチル化検出用オリゴヌクレオチド固定化基板
US20040253741A1 (en) * 2003-02-06 2004-12-16 Alexander Star Analyte detection in liquids with carbon nanotube field effect transistor devices
US20070048181A1 (en) * 2002-09-05 2007-03-01 Chang Daniel M Carbon dioxide nanosensor, and respiratory CO2 monitors
US20040026684A1 (en) 2002-04-02 2004-02-12 Nanosys, Inc. Nanowire heterostructures for encoding information
AU2003231300A1 (en) * 2002-05-04 2003-11-17 Aviva Biosciences Corporation Apparatus including ion transport detecting structures and methods of use
CA2485560A1 (en) * 2002-05-10 2004-06-03 Engeneos, Inc. Unique recognition sequences and methods of use thereof in protein analysis
WO2003104789A1 (en) 2002-06-06 2003-12-18 Rutgers, The State University Of New Jersey MULTIFUNCTIONAL BIOSENSOR BASED ON ZnO NANOSTRUCTURES
US6946851B2 (en) * 2002-07-03 2005-09-20 The Regents Of The University Of California Carbon nanotube array based sensor
WO2004020662A2 (en) * 2002-08-27 2004-03-11 Epigenomics Ag Method and nucleic acids for the analysis of breast cell proliferative disorders
US20060099135A1 (en) * 2002-09-10 2006-05-11 Yodh Arjun G Carbon nanotubes: high solids dispersions and nematic gels thereof
JP2006501056A (ja) * 2002-09-25 2006-01-12 カリフォルニア インスティテュート オブ テクノロジー ミクロ流体大規模集積
WO2004034025A2 (en) 2002-10-10 2004-04-22 Nanosys, Inc. Nano-chem-fet based biosensors
ATE423306T1 (de) * 2002-11-14 2009-03-15 Fraunhofer Ges Forschung Ionensensitiver feldeffekttransistor und verfahren zum herstellen eines ionensensitiven feldeffekttransistors
US20040200734A1 (en) 2002-12-19 2004-10-14 Co Man Sung Nanotube-based sensors for biomolecules
CN1517707A (zh) * 2003-01-16 2004-08-04 中国科学院电子学研究所 一种用于制备毛细管沟道及其取样的方法
US6855606B2 (en) * 2003-02-20 2005-02-15 Taiwan Semiconductor Manufacturing Company, Ltd. Semiconductor nano-rod devices
US7385266B2 (en) 2003-05-14 2008-06-10 Nantero, Inc. Sensor platform using a non-horizontally oriented nanotube element
TWI346202B (en) * 2003-05-14 2011-08-01 Nantero Inc Sensor platform using a non-horizontally oriented nanotube element and methods of making sensor,capacitive structure and resistive structure
US7910064B2 (en) 2003-06-03 2011-03-22 Nanosys, Inc. Nanowire-based sensor configurations
US7670831B2 (en) 2003-06-13 2010-03-02 Korea Advanced Institute Of Science And Technology Conductive carbon nanotubes dotted with metal and method for fabricating a biosensor using the same
US7416911B2 (en) 2003-06-24 2008-08-26 California Institute Of Technology Electrochemical method for attaching molecular and biomolecular structures to semiconductor microstructures and nanostructures
CN1852863A (zh) * 2003-07-29 2006-10-25 威廉马歇莱思大学 碳纳米管的选择性官能化
US8346482B2 (en) * 2003-08-22 2013-01-01 Fernandez Dennis S Integrated biosensor and simulation system for diagnosis and therapy
TWI253502B (en) * 2003-08-26 2006-04-21 Ind Tech Res Inst A structure and manufacturing process of a nano device transistor for a biosensor
US7632234B2 (en) 2003-08-29 2009-12-15 Medtronic, Inc. Implantable biosensor devices for monitoring cardiac marker molecules
US8105780B2 (en) * 2003-09-22 2012-01-31 Agency For Science, Technology And Research Device and method of detecting mutations and polymorphisms in DNA
US20050253137A1 (en) * 2003-11-20 2005-11-17 President And Fellows Of Harvard College Nanoscale arrays, robust nanostructures, and related devices
US7394118B2 (en) * 2004-03-09 2008-07-01 University Of Southern California Chemical sensor using semiconducting metal oxide nanowires
WO2006071247A2 (en) 2004-03-30 2006-07-06 California Institute Of Technology Diagnostic assays including multiplexed lateral flow immunoassays with quantum dots
US7785922B2 (en) 2004-04-30 2010-08-31 Nanosys, Inc. Methods for oriented growth of nanowires on patterned substrates
JP2007535413A (ja) * 2004-04-30 2007-12-06 ナノシス・インコーポレイテッド ナノワイヤ成長および採取のための系および方法
EP1766400B1 (en) 2004-06-03 2009-04-15 Meso Scale Technologies, LLC Methods for conducting whole blood assays
US20070264623A1 (en) 2004-06-15 2007-11-15 President And Fellows Of Harvard College Nanosensors
WO2007001402A2 (en) 2004-09-30 2007-01-04 E. I. Du Pont De Nemours And Company Redox potential mediated, heterogeneous, carbon nanotube biosensing
US7473943B2 (en) * 2004-10-15 2009-01-06 Nanosys, Inc. Gate configuration for nanowire electronic devices
US7560366B1 (en) * 2004-12-02 2009-07-14 Nanosys, Inc. Nanowire horizontal growth and substrate removal
US7544978B2 (en) * 2005-01-24 2009-06-09 Lawrence Livermore National Security, Llc Lipid nanotube or nanowire sensor
US20060188934A1 (en) * 2005-02-22 2006-08-24 Ying-Lan Chang System and method for implementing a high-sensitivity sensor with improved stability
EP1902143A1 (en) 2005-03-29 2008-03-26 Applera Corporation Nanowire-based system for analysis of nucleic acids
US20100227382A1 (en) 2005-05-25 2010-09-09 President And Fellows Of Harvard College Nanoscale sensors
KR100748408B1 (ko) * 2005-06-28 2007-08-10 한국화학연구원 압타머를 이용한 탄소 나노튜브 트랜지스터 바이오센서 및이것을 이용한 타겟물질 검출 방법
US20070001581A1 (en) 2005-06-29 2007-01-04 Stasiak James W Nanostructure based light emitting devices and associated methods
US7410912B2 (en) * 2005-09-02 2008-08-12 The Hong Kong Polytechnic University Methods of manufacturing metal oxide nanowires
US20070092870A1 (en) * 2005-10-20 2007-04-26 Yiping Zhao Detection of biomolecules
CN102554261B (zh) * 2005-11-10 2014-08-13 住友金属矿山株式会社 铟类纳米线、氧化物纳米线与导电性氧化物纳米线以及它们的制造方法
EP1952444B1 (en) * 2005-11-18 2011-07-27 Nxp B.V. Metal-base nanowire transistor
US20070161029A1 (en) * 2005-12-05 2007-07-12 Panomics, Inc. High throughput profiling of methylation status of promoter regions of genes
WO2007133288A1 (en) * 2005-12-15 2007-11-22 The Trustees Of Columbia University In The City Of New York Sensing devices from molecular electronic devices utilizing hexabenzocoronenes
WO2008027078A2 (en) 2006-03-15 2008-03-06 President And Fellows Of Harvard College Nanobioelectronics
US7718995B2 (en) 2006-06-20 2010-05-18 Panasonic Corporation Nanowire, method for fabricating the same, and device having nanowires
CA2667012A1 (en) 2006-10-26 2008-05-02 Abbott Laboratories Immunoassay of analytes in samples containing endogenous anti-analyte antibodies
EP2095100B1 (en) * 2006-11-22 2016-09-21 President and Fellows of Harvard College Method of operating a nanowire field effect transistor sensor
WO2008070058A2 (en) * 2006-12-04 2008-06-12 Purdue Research Foundation Method and apparatus for detection of molecules using sensor array
US20080200342A1 (en) * 2007-02-15 2008-08-21 Rao Rupa S Device, Array, And Methods For Disease Detection And Analysis
US8956823B2 (en) * 2007-08-20 2015-02-17 Bio-Rad Laboratories, Inc. Anti-antibody reagent
US7795677B2 (en) 2007-09-05 2010-09-14 International Business Machines Corporation Nanowire field-effect transistors
EP2210093A4 (en) 2007-10-01 2012-12-05 Univ Southern California METHODS OF USING AND CONSTRUCTING NANOCAPTOR PLATFORMS
US20100204062A1 (en) * 2008-11-07 2010-08-12 University Of Southern California Calibration methods for multiplexed sensor arrays
US20100256344A1 (en) 2009-04-03 2010-10-07 University Of Southern California Surface modification of nanosensor platforms to increase sensitivity and reproducibility
WO2011146881A1 (en) 2010-05-20 2011-11-24 University Of Southern California Pan-antibody assays - principles, methods, and devices

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004515782A (ja) * 2000-12-11 2004-05-27 プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ ナノセンサ
JP2006505806A (ja) * 2002-11-08 2006-02-16 ナノミックス・インコーポレーテッド ナノチューブをベースとする生体分子の電子検知
JP2004294087A (ja) * 2003-03-25 2004-10-21 Japan Science & Technology Agency pチャンネル電界効果トランジスタ及びそれを用いたセンサ
WO2006024023A2 (en) * 2004-08-24 2006-03-02 Nanomix, Inc. Nanotube sensor devices for dna detection
JP2006222279A (ja) * 2005-02-10 2006-08-24 Japan Science & Technology Agency n型トランジスタ、n型トランジスタセンサ及びn型トランジスタ用チャネルの製造方法
JP2008082988A (ja) * 2006-09-28 2008-04-10 Hokkaido Univ 多段階増幅を利用した検出方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6013062841; Gunho Jo et al.: 'Electronic Transport in Indium Oxide Nanowire Field Effect Transistors' Nanotechnology Materials and Devices Conference 2006 IEEE Volume 1, p.494-495 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016021693A1 (ja) * 2014-08-08 2016-02-11 日本化薬株式会社 電界効果型トランジスタおよびそれを用いたセンサ
JPWO2016021693A1 (ja) * 2014-08-08 2017-07-06 日本化薬株式会社 電界効果型トランジスタおよびそれを用いたセンサ
JP2018504612A (ja) * 2014-11-07 2018-02-15 プロテオセンス 検体を検出するためのデバイス、システム、及び方法

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