CA2701401C - Microfluidic integration with nanosensor platform - Google Patents
Microfluidic integration with nanosensor platform Download PDFInfo
- Publication number
- CA2701401C CA2701401C CA2701401A CA2701401A CA2701401C CA 2701401 C CA2701401 C CA 2701401C CA 2701401 A CA2701401 A CA 2701401A CA 2701401 A CA2701401 A CA 2701401A CA 2701401 C CA2701401 C CA 2701401C
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- CA
- Canada
- Prior art keywords
- nanosensor
- array
- chambers
- microfluidic
- arrays
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/403—Cells and electrode assemblies
- G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
- G01N27/4146—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS involving nanosized elements, e.g. nanotubes, nanowires
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Nanotechnology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Electrochemistry (AREA)
- Materials Engineering (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Composite Materials (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97677407P | 2007-10-01 | 2007-10-01 | |
| US97678007P | 2007-10-01 | 2007-10-01 | |
| US60/976,780 | 2007-10-01 | ||
| US60/976,774 | 2007-10-01 | ||
| PCT/US2008/078491 WO2009046136A2 (en) | 2007-10-01 | 2008-10-01 | Microfluidic integration with nanosensor platform |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2701401A1 CA2701401A1 (en) | 2009-04-09 |
| CA2701401C true CA2701401C (en) | 2013-05-14 |
Family
ID=40526648
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2701401A Expired - Fee Related CA2701401C (en) | 2007-10-01 | 2008-10-01 | Microfluidic integration with nanosensor platform |
| CA2701447A Abandoned CA2701447A1 (en) | 2007-10-01 | 2008-10-01 | Methods of using and constructing nanosensor platforms |
| CA2701380A Expired - Fee Related CA2701380C (en) | 2007-10-01 | 2008-10-01 | Detection of methylated dna and dna mutations |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2701447A Abandoned CA2701447A1 (en) | 2007-10-01 | 2008-10-01 | Methods of using and constructing nanosensor platforms |
| CA2701380A Expired - Fee Related CA2701380C (en) | 2007-10-01 | 2008-10-01 | Detection of methylated dna and dna mutations |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20100260745A1 (enExample) |
| EP (2) | EP2210093A4 (enExample) |
| JP (2) | JP2011518311A (enExample) |
| CN (1) | CN102016570A (enExample) |
| CA (3) | CA2701401C (enExample) |
| WO (3) | WO2009085356A2 (enExample) |
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| JP5211790B2 (ja) * | 2007-03-26 | 2013-06-12 | 住友化学株式会社 | Ｄｎａメチル化測定方法 |
| EP2210093A4 (en) | 2007-10-01 | 2012-12-05 | Univ Southern California | METHODS OF USING AND CONSTRUCTING NANOCAPTOR PLATFORMS |
| WO2013154750A1 (en) | 2012-04-10 | 2013-10-17 | The Trustees Of Columbia Unversity In The City Of New York | Systems and methods for biological ion channel interfaces |
| US20100204062A1 (en) * | 2008-11-07 | 2010-08-12 | University Of Southern California | Calibration methods for multiplexed sensor arrays |
| US20100256344A1 (en) * | 2009-04-03 | 2010-10-07 | University Of Southern California | Surface modification of nanosensor platforms to increase sensitivity and reproducibility |
| WO2011017077A2 (en) * | 2009-07-27 | 2011-02-10 | Trustees Of Boston University | Nanochannel-based sensor system with controlled sensitivity |
| GB201004147D0 (en) * | 2010-03-12 | 2010-04-28 | Dna Electronics Ltd | Method and apparatus for sensing methylation |
| DE202010017796U1 (de) * | 2010-09-22 | 2012-09-07 | Actc-Anti Cirme Technology Corporations Gmbh | Substanz zur gerichtsverwertbaren Markierung |
| CN102033089A (zh) * | 2010-10-27 | 2011-04-27 | 清华大学 | 生物传感器，其封装结构及检测系统 |
| EP3444600B1 (en) | 2011-01-11 | 2020-05-13 | The Trustees of Columbia University in the City of New York | System and methods for single-molecule detection using nanotubes |
| US8450131B2 (en) * | 2011-01-11 | 2013-05-28 | Nanohmics, Inc. | Imprinted semiconductor multiplex detection array |
| CN103380369B (zh) | 2011-02-23 | 2016-12-28 | 纽约市哥伦比亚大学理事会 | 使用纳米孔进行单分子检测的系统和方法 |
| US9599614B2 (en) | 2011-03-14 | 2017-03-21 | Yale University | Calibration of nanostructure sensors |
| US20130201316A1 (en) | 2012-01-09 | 2013-08-08 | May Patents Ltd. | System and method for server based control |
| WO2013158280A1 (en) | 2012-04-20 | 2013-10-24 | The Trustees Of Columbia University In The City Of New York | Systems and methods for single-molecule nucleic-acid assay platforms |
| US10088477B2 (en) | 2012-07-30 | 2018-10-02 | The Regents Of The University Of California | Biomolecular detection test strip design |
| CN104685069A (zh) | 2012-08-17 | 2015-06-03 | 拜奥-奈穆斯公司 | 核酸分类 |
| US10457978B2 (en) * | 2012-08-17 | 2019-10-29 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Cyclopentane-peptide nucleic acids for qualitative and quantitative detection of nucleic acids |
| EP2735868B1 (en) * | 2012-11-26 | 2015-11-25 | University College Cork | Nanowire electrode sensor |
| US9316612B2 (en) | 2013-01-04 | 2016-04-19 | Yale University | Regenerative nanosensor devices |
| KR102056928B1 (ko) * | 2013-01-16 | 2019-12-18 | 삼성디스플레이 주식회사 | 터치스크린 패널 및 그의 제조방법 |
| US9435896B2 (en) * | 2013-07-31 | 2016-09-06 | Globalfoundries Inc. | Radiation detector based on charged self-assembled monolayers on nanowire devices |
| WO2016021693A1 (ja) * | 2014-08-08 | 2016-02-11 | 日本化薬株式会社 | 電界効果型トランジスタおよびそれを用いたセンサ |
| AU2015342795A1 (en) * | 2014-11-07 | 2017-06-01 | Proteosense | Devices, systems, and methods for the detection of analytes |
| DE102014016712B4 (de) * | 2014-11-13 | 2022-12-01 | Dräger Safety AG & Co. KGaA | Transportables Chipmesssystem und Verfahren zum Betrieb eines transportablen Chipmesssystems |
| WO2016085911A1 (en) * | 2014-11-26 | 2016-06-02 | Washington University | Bioplasmonic detection of biomarkers in body fluids using peptide recognition elements |
| WO2016122630A1 (en) | 2015-01-30 | 2016-08-04 | Hewlett-Packard Development Company, L.P. | Signal transmission bandwidth allocation on a microfluidic chip |
| KR102338748B1 (ko) * | 2015-04-21 | 2021-12-15 | 삼성디스플레이 주식회사 | 터치 스크린 패널 및 이의 제조 방법 |
| US20170015699A1 (en) * | 2015-07-15 | 2017-01-19 | Orizhan Bioscience Limited | Partially Neutral Single-Stranded Oligonucleotide |
| US20180356405A1 (en) * | 2015-09-29 | 2018-12-13 | Essenlix Corp. | Method of Detecting an Analyte in a Sample |
| US10502725B2 (en) * | 2015-10-13 | 2019-12-10 | University Of Utah Research Foundation | Ultra-low power digital chemical analyzers |
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| CN115753941A (zh) * | 2016-06-30 | 2023-03-07 | 格拉夫威尔科技公司 | 极性流体门控场效应器件 |
| CN106483191B (zh) * | 2016-10-27 | 2019-03-08 | 吉林大学 | 一种通过消除甜点效应提高质谱检测重复性的方法 |
| US20200294401A1 (en) | 2017-09-04 | 2020-09-17 | Nng Software Developing And Commercial Llc. | A Method and Apparatus for Collecting and Using Sensor Data from a Vehicle |
| CN109470679B (zh) * | 2017-09-08 | 2021-04-23 | 清华大学 | 用于分子检测的分子载体 |
| WO2019152820A1 (en) * | 2018-02-02 | 2019-08-08 | Fred Hutchinson Cancer Research Center | Methods for treating facioscapulohumeral muscular dystrophy |
| WO2020035852A2 (en) | 2018-08-14 | 2020-02-20 | Neurotrigger Ltd. | Method and apparatus for transcutaneous facial nerve stimulation and applications thereof |
| US10968098B2 (en) * | 2018-10-02 | 2021-04-06 | International Business Machines Corporation | Selective functionalization of sensing surface with nanoscale spatial resolution |
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| US11290708B2 (en) | 2019-02-19 | 2022-03-29 | Edgy Bees Ltd. | Estimating real-time delay of a video data stream |
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-
2008
- 2008-10-01 EP EP08867520A patent/EP2210093A4/en not_active Withdrawn
- 2008-10-01 US US12/680,833 patent/US20100260745A1/en not_active Abandoned
- 2008-10-01 CN CN2008801175504A patent/CN102016570A/zh active Pending
- 2008-10-01 WO PCT/US2008/078502 patent/WO2009085356A2/en not_active Ceased
- 2008-10-01 CA CA2701401A patent/CA2701401C/en not_active Expired - Fee Related
- 2008-10-01 US US12/680,821 patent/US20110275544A1/en not_active Abandoned
- 2008-10-01 WO PCT/US2008/078491 patent/WO2009046136A2/en not_active Ceased
- 2008-10-01 CA CA2701447A patent/CA2701447A1/en not_active Abandoned
- 2008-10-01 US US12/680,806 patent/US8609333B2/en active Active
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- 2008-10-01 JP JP2010528111A patent/JP2011518311A/ja not_active Ceased
- 2008-10-01 EP EP08835597A patent/EP2205714A4/en not_active Withdrawn
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| EP2210093A2 (en) | 2010-07-28 |
| CA2701401A1 (en) | 2009-04-09 |
| WO2009046110A1 (en) | 2009-04-09 |
| WO2009046136A2 (en) | 2009-04-09 |
| EP2210093A4 (en) | 2012-12-05 |
| CA2701447A1 (en) | 2009-07-09 |
| EP2205714A4 (en) | 2011-01-12 |
| CN102016570A (zh) | 2011-04-13 |
| CA2701380C (en) | 2014-03-11 |
| US20100292348A1 (en) | 2010-11-18 |
| JP2011518311A (ja) | 2011-06-23 |
| WO2009085356A8 (en) | 2010-04-29 |
| US20100260745A1 (en) | 2010-10-14 |
| WO2009085356A2 (en) | 2009-07-09 |
| CA2701380A1 (en) | 2009-04-09 |
| WO2009046136A3 (en) | 2009-05-22 |
| JP2012163578A (ja) | 2012-08-30 |
| EP2205714A1 (en) | 2010-07-14 |
| US20110275544A1 (en) | 2011-11-10 |
| US8609333B2 (en) | 2013-12-17 |
| WO2009085356A3 (en) | 2009-10-15 |
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