JP2011516436A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011516436A5 JP2011516436A5 JP2011502260A JP2011502260A JP2011516436A5 JP 2011516436 A5 JP2011516436 A5 JP 2011516436A5 JP 2011502260 A JP2011502260 A JP 2011502260A JP 2011502260 A JP2011502260 A JP 2011502260A JP 2011516436 A5 JP2011516436 A5 JP 2011516436A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- tissue
- polymer
- blood
- differentiation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 229920000642 polymer Polymers 0.000 claims 8
- 239000008280 blood Substances 0.000 claims 7
- 210000004369 blood Anatomy 0.000 claims 7
- 210000001519 tissue Anatomy 0.000 claims 7
- 210000002798 bone marrow cell Anatomy 0.000 claims 5
- 210000000130 stem cell Anatomy 0.000 claims 5
- 102000003951 Erythropoietin Human genes 0.000 claims 4
- 108090000394 Erythropoietin Proteins 0.000 claims 4
- 230000004069 differentiation Effects 0.000 claims 4
- 229940105423 erythropoietin Drugs 0.000 claims 4
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical group [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 4
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims 3
- 102000009123 Fibrin Human genes 0.000 claims 3
- 108010073385 Fibrin Proteins 0.000 claims 3
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 3
- 241001465754 Metazoa Species 0.000 claims 3
- 108090000190 Thrombin Proteins 0.000 claims 3
- 210000000988 bone and bone Anatomy 0.000 claims 3
- 229910001424 calcium ion Inorganic materials 0.000 claims 3
- 229950003499 fibrin Drugs 0.000 claims 3
- 238000006116 polymerization reaction Methods 0.000 claims 3
- 230000008929 regeneration Effects 0.000 claims 3
- 238000011069 regeneration method Methods 0.000 claims 3
- 229960004072 thrombin Drugs 0.000 claims 3
- 230000000472 traumatic effect Effects 0.000 claims 3
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 claims 2
- 102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 claims 2
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims 2
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 claims 2
- 210000001608 connective tissue cell Anatomy 0.000 claims 2
- 210000002950 fibroblast Anatomy 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 210000002540 macrophage Anatomy 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 230000035755 proliferation Effects 0.000 claims 2
- 239000003634 thrombocyte concentrate Substances 0.000 claims 2
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims 1
- 102000007327 Protamines Human genes 0.000 claims 1
- 108010007568 Protamines Proteins 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 230000000975 bioactive effect Effects 0.000 claims 1
- 239000000316 bone substitute Substances 0.000 claims 1
- 230000024245 cell differentiation Effects 0.000 claims 1
- 230000010261 cell growth Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 210000001612 chondrocyte Anatomy 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 210000002889 endothelial cell Anatomy 0.000 claims 1
- 210000002744 extracellular matrix Anatomy 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 230000012010 growth Effects 0.000 claims 1
- 239000003102 growth factor Substances 0.000 claims 1
- 239000000122 growth hormone Substances 0.000 claims 1
- 229940088597 hormone Drugs 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 229940048914 protamine Drugs 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08006238 | 2008-03-31 | ||
| EP08006238.3 | 2008-03-31 | ||
| PCT/EP2009/002135 WO2009121503A2 (de) | 2008-03-31 | 2009-03-24 | Verfahren und zusammensetzung zur regeneration von gewebe mit hilfe von stamm- oder knochenmarkzellen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011516436A JP2011516436A (ja) | 2011-05-26 |
| JP2011516436A5 true JP2011516436A5 (https=) | 2012-05-17 |
Family
ID=41103846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011502260A Pending JP2011516436A (ja) | 2008-03-31 | 2009-03-24 | 幹細胞又は骨髄細胞を用いる組織の再生のための方法及び組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20110020299A1 (https=) |
| EP (1) | EP2273997B1 (https=) |
| JP (1) | JP2011516436A (https=) |
| CN (1) | CN101980714A (https=) |
| AU (1) | AU2009231139A1 (https=) |
| CA (1) | CA2719437A1 (https=) |
| RU (1) | RU2491076C2 (https=) |
| WO (1) | WO2009121503A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110280838A1 (en) * | 2007-12-27 | 2011-11-17 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of intervertebral disc degeneration using human umbilical cord tissue-derived cells |
| WO2011153512A2 (en) * | 2010-06-03 | 2011-12-08 | Indiana University Research And Technology Corporation | Use of compounds with thrombopoietic activity to promote bone growth and healing |
| US20150065425A1 (en) * | 2013-09-02 | 2015-03-05 | Muffin Incorporated | Products comprising an extracellular matrix material and osteogenic protein |
| CN104524636B (zh) * | 2014-12-19 | 2017-06-16 | 中国人民解放军第四军医大学 | 通过定向诱导骨髓间充质干细胞获得组织工程软骨的方法 |
| RU2614665C1 (ru) * | 2015-12-18 | 2017-03-28 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Способ стимуляции репаративного ангиогенеза и регенерации соединительной ткани, при её повреждении, методом генной терапии с использованием видоспецифичных генов белковых факторов vegf и fgf2, в ветеринарии, и генетическая конструкция для реализации заявленного способа |
| CN106581772B (zh) * | 2016-12-02 | 2020-02-18 | 四川大学华西医院 | 携带G-CSF缓释系统的Fibrin-HA水凝胶及其制备方法和用途 |
| KR101772449B1 (ko) | 2016-12-27 | 2017-08-30 | 주식회사 하이센스바이오 | 신규한 펩타이드 |
| RU2687007C2 (ru) * | 2017-09-12 | 2019-05-06 | Общество с ограниченной ответственностью "Клеточные Системы" | Способ биотехнологического восстановления кожного покрова аллогенными стволовыми клетками человека |
| JP7110360B2 (ja) | 2017-10-09 | 2022-08-01 | テルモ ビーシーティー バイオテクノロジーズ,エルエルシー | 凍結乾燥方法 |
| KR101943978B1 (ko) | 2017-12-28 | 2019-01-30 | 주식회사 하이센스바이오 | 신규한 펩타이드 |
| RU2669726C1 (ru) * | 2018-01-10 | 2018-10-15 | Диана Малхазовна Обидняк | Способ повышения эффективности вспомогательных репродуктивных технологий у пациенток с повторными неэффективными попытками имплантации |
| CN113597532B (zh) | 2019-03-14 | 2023-02-17 | 泰尔茂比司特生物技术有限公司 | 冻干容器填充固定装置、系统及使用方法 |
| RU2747589C1 (ru) * | 2019-12-09 | 2021-05-11 | Руслан Яверович Атлуханов | Способ лечения повреждения мениска коленного сустава |
| CN116712597B (zh) * | 2023-06-12 | 2026-04-17 | 广州正源生物技术有限公司 | 一种复合生物敷料及其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE439849T1 (de) * | 1996-04-19 | 2009-09-15 | Osiris Therapeutics Inc | Die wiederherstellung und verstärkung von knochen mittels mesenchymalen stammzellen |
| WO2000018885A1 (en) * | 1998-09-29 | 2000-04-06 | Gamida Cell Ltd. | Methods of controlling proliferation and differentiation of stem and progenitor cells |
| AU2003253015A1 (en) * | 2002-06-20 | 2004-01-06 | Bionethos Holding Gmbh | Method and device for multiplying and differentiating cells in the presence of growth factors and of a biological matrix or of a supporting structure |
| US20040191215A1 (en) * | 2003-03-25 | 2004-09-30 | Michael Froix | Compositions for induction of a therapeutic response |
| ATE469654T1 (de) * | 2003-12-30 | 2010-06-15 | Augustinus Bader | Verwendung des erythropoietins zur regeneration von lebergewebe |
| DE102004004509B4 (de) * | 2004-01-23 | 2010-07-01 | Epoplus Gmbh Co.Kg | Einsatz von niedrig dosiertem Erythropoietin zur Stimulation endothelialer Vorläuferzellen sowie zur Organregeneration und Progressionsverlangsamung von Endorganschäden |
| ITRM20060289A1 (it) * | 2006-05-31 | 2007-12-01 | Ranieri Cancedda | Bio membrana ingegnerizzata osteo angiogenica e suoi usi per la rigenerazione di tessuto osseo |
-
2009
- 2009-03-24 RU RU2010142988/15A patent/RU2491076C2/ru active
- 2009-03-24 EP EP09726923.7A patent/EP2273997B1/de active Active
- 2009-03-24 AU AU2009231139A patent/AU2009231139A1/en not_active Abandoned
- 2009-03-24 JP JP2011502260A patent/JP2011516436A/ja active Pending
- 2009-03-24 CA CA2719437A patent/CA2719437A1/en not_active Abandoned
- 2009-03-24 US US12/935,532 patent/US20110020299A1/en not_active Abandoned
- 2009-03-24 WO PCT/EP2009/002135 patent/WO2009121503A2/de not_active Ceased
- 2009-03-24 CN CN2009801112567A patent/CN101980714A/zh active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011516436A5 (https=) | ||
| Korpayev et al. | Chitosan/collagen based biomimetic osteochondral tissue constructs: a growth factor-free approach | |
| Rao et al. | Biomaterial-based Schwann cell transplantation and Schwann cell-derived biomaterials for nerve regeneration | |
| Tang et al. | Human embryonic stem cell encapsulation in alginate microbeads in macroporous calcium phosphate cement for bone tissue engineering | |
| Carvalho et al. | Undifferentiated human adipose‐derived stromal/stem cells loaded onto wet‐spun starch–polycaprolactone scaffolds enhance bone regeneration: Nude mice calvarial defect in vivo study | |
| RU2010142988A (ru) | Способ и композиция для регенерации тканей с помощью стволовых или костномозговых клеток | |
| Shen et al. | Implications of adipose-derived stromal cells in a 3D culture system for osteogenic differentiation: an in vitro and in vivo investigation | |
| Yin et al. | Controlled release of FGF-2 and BMP-2 in tissue engineered periosteum promotes bone repair in rats | |
| Sadeghinia et al. | Nano-hydroxy apatite/chitosan/gelatin scaffolds enriched by a combination of platelet-rich plasma and fibrin glue enhance proliferation and differentiation of seeded human dental pulp stem cells | |
| CN102341112B (zh) | 产生组织的方法和装置以及所获得的组织 | |
| Kakabadze et al. | Reconstruction of mandibular defects with autogenous bone and decellularized bovine bone grafts with freeze‑dried bone marrow stem cell paracrine factors | |
| Huang et al. | Osteogenic differentiation of muscle satellite cells induced by platelet-rich plasma encapsulated in three-dimensional alginate scaffold | |
| Zhu et al. | A comparative histologic analysis of tissue-engineered bone using platelet-rich plasma and platelet-enriched fibrin glue | |
| Wang et al. | Hydrogel fibers encapsulating human stem cells in an injectable calcium phosphate scaffold for bone tissue engineering | |
| Liu et al. | Genipin modified lyophilized platelet-rich fibrin scaffold for sustained release of growth factors to promote bone regeneration | |
| Li et al. | Use of a biological reactor and platelet-rich plasma for the construction of tissue-engineered bone to repair articular cartilage defects | |
| KR20200087748A (ko) | 지방 유래 줄기세포를 포함하는 생체재료 및 이를 생산하는 방법 | |
| AU2024278089A1 (en) | Biomaterial comprising adipose-derived stem cells and gelatin and method for producing the same | |
| Gessmann et al. | Plasma clots gelled by different amounts of calcium for stem cell delivery | |
| Canciani et al. | Human adipose-derived stem cells on rapid prototyped three-dimensional hydroxyapatite/beta-tricalcium phosphate scaffold | |
| Braga et al. | Bioactive fibrin scaffolds for use in musculoskeletal regenerative medicine | |
| Dahabreh et al. | Ability of bone graft substitutes to support the osteoprogenitor cells: An in-vitro study | |
| Kim et al. | Effects of polycaprolactone-tricalcium phosphate, recombinant human bone morphogenetic protein-2 and dog mesenchymal stem cells on bone formation: pilot study in dogs | |
| Chen et al. | Synergetic effects of hBMSCs and hPCs in osteogenic differentiation and their capacity in the repair of critical-sized femoral condyle defects | |
| Song et al. | Quantitative analysis of factors influencing tissue-engineered bone formation by detecting the expression levels of alkaline phosphatase and bone γ-carboxyglutamate protein 2 |