CN101980714A - 借助干细胞或骨髓细胞进行组织再生的方法和组合物 - Google Patents

借助干细胞或骨髓细胞进行组织再生的方法和组合物 Download PDF

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Publication number
CN101980714A
CN101980714A CN2009801112567A CN200980111256A CN101980714A CN 101980714 A CN101980714 A CN 101980714A CN 2009801112567 A CN2009801112567 A CN 2009801112567A CN 200980111256 A CN200980111256 A CN 200980111256A CN 101980714 A CN101980714 A CN 101980714A
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cell
tissue
cells
blood
polymerizate
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奥古斯蒂努斯·巴德
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/19Platelets; Megacaryocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1816Erythropoietin [EPO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4833Thrombin (3.4.21.5)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2009801112567A 2008-03-31 2009-03-24 借助干细胞或骨髓细胞进行组织再生的方法和组合物 Pending CN101980714A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08006238 2008-03-31
EP08006238.3 2008-03-31
PCT/EP2009/002135 WO2009121503A2 (de) 2008-03-31 2009-03-24 Verfahren und zusammensetzung zur regeneration von gewebe mit hilfe von stamm- oder knochenmarkzellen

Publications (1)

Publication Number Publication Date
CN101980714A true CN101980714A (zh) 2011-02-23

Family

ID=41103846

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801112567A Pending CN101980714A (zh) 2008-03-31 2009-03-24 借助干细胞或骨髓细胞进行组织再生的方法和组合物

Country Status (8)

Country Link
US (1) US20110020299A1 (https=)
EP (1) EP2273997B1 (https=)
JP (1) JP2011516436A (https=)
CN (1) CN101980714A (https=)
AU (1) AU2009231139A1 (https=)
CA (1) CA2719437A1 (https=)
RU (1) RU2491076C2 (https=)
WO (1) WO2009121503A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104524636A (zh) * 2014-12-19 2015-04-22 中国人民解放军第四军医大学 通过定向诱导骨髓间充质干细胞获得组织工程软骨的方法
CN106581772A (zh) * 2016-12-02 2017-04-26 四川大学华西医院 携带G‑CSF缓释系统的Fibrin‑HA水凝胶及其制备方法和用途
CN116712597A (zh) * 2023-06-12 2023-09-08 广州正源生物技术有限公司 一种复合生物敷料及其制备方法和应用

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110280838A1 (en) * 2007-12-27 2011-11-17 Advanced Technologies And Regenerative Medicine, Llc Treatment of intervertebral disc degeneration using human umbilical cord tissue-derived cells
WO2011153512A2 (en) * 2010-06-03 2011-12-08 Indiana University Research And Technology Corporation Use of compounds with thrombopoietic activity to promote bone growth and healing
US20150065425A1 (en) * 2013-09-02 2015-03-05 Muffin Incorporated Products comprising an extracellular matrix material and osteogenic protein
RU2614665C1 (ru) * 2015-12-18 2017-03-28 федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) Способ стимуляции репаративного ангиогенеза и регенерации соединительной ткани, при её повреждении, методом генной терапии с использованием видоспецифичных генов белковых факторов vegf и fgf2, в ветеринарии, и генетическая конструкция для реализации заявленного способа
KR101772449B1 (ko) 2016-12-27 2017-08-30 주식회사 하이센스바이오 신규한 펩타이드
RU2687007C2 (ru) * 2017-09-12 2019-05-06 Общество с ограниченной ответственностью "Клеточные Системы" Способ биотехнологического восстановления кожного покрова аллогенными стволовыми клетками человека
JP7110360B2 (ja) 2017-10-09 2022-08-01 テルモ ビーシーティー バイオテクノロジーズ,エルエルシー 凍結乾燥方法
KR101943978B1 (ko) 2017-12-28 2019-01-30 주식회사 하이센스바이오 신규한 펩타이드
RU2669726C1 (ru) * 2018-01-10 2018-10-15 Диана Малхазовна Обидняк Способ повышения эффективности вспомогательных репродуктивных технологий у пациенток с повторными неэффективными попытками имплантации
CN113597532B (zh) 2019-03-14 2023-02-17 泰尔茂比司特生物技术有限公司 冻干容器填充固定装置、系统及使用方法
RU2747589C1 (ru) * 2019-12-09 2021-05-11 Руслан Яверович Атлуханов Способ лечения повреждения мениска коленного сустава

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE439849T1 (de) * 1996-04-19 2009-09-15 Osiris Therapeutics Inc Die wiederherstellung und verstärkung von knochen mittels mesenchymalen stammzellen
WO2000018885A1 (en) * 1998-09-29 2000-04-06 Gamida Cell Ltd. Methods of controlling proliferation and differentiation of stem and progenitor cells
AU2003253015A1 (en) * 2002-06-20 2004-01-06 Bionethos Holding Gmbh Method and device for multiplying and differentiating cells in the presence of growth factors and of a biological matrix or of a supporting structure
US20040191215A1 (en) * 2003-03-25 2004-09-30 Michael Froix Compositions for induction of a therapeutic response
ATE469654T1 (de) * 2003-12-30 2010-06-15 Augustinus Bader Verwendung des erythropoietins zur regeneration von lebergewebe
DE102004004509B4 (de) * 2004-01-23 2010-07-01 Epoplus Gmbh Co.Kg Einsatz von niedrig dosiertem Erythropoietin zur Stimulation endothelialer Vorläuferzellen sowie zur Organregeneration und Progressionsverlangsamung von Endorganschäden
ITRM20060289A1 (it) * 2006-05-31 2007-12-01 Ranieri Cancedda Bio membrana ingegnerizzata osteo angiogenica e suoi usi per la rigenerazione di tessuto osseo

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104524636A (zh) * 2014-12-19 2015-04-22 中国人民解放军第四军医大学 通过定向诱导骨髓间充质干细胞获得组织工程软骨的方法
CN104524636B (zh) * 2014-12-19 2017-06-16 中国人民解放军第四军医大学 通过定向诱导骨髓间充质干细胞获得组织工程软骨的方法
CN106581772A (zh) * 2016-12-02 2017-04-26 四川大学华西医院 携带G‑CSF缓释系统的Fibrin‑HA水凝胶及其制备方法和用途
CN106581772B (zh) * 2016-12-02 2020-02-18 四川大学华西医院 携带G-CSF缓释系统的Fibrin-HA水凝胶及其制备方法和用途
CN116712597A (zh) * 2023-06-12 2023-09-08 广州正源生物技术有限公司 一种复合生物敷料及其制备方法和应用
CN116712597B (zh) * 2023-06-12 2026-04-17 广州正源生物技术有限公司 一种复合生物敷料及其制备方法和应用

Also Published As

Publication number Publication date
EP2273997B1 (de) 2016-01-13
JP2011516436A (ja) 2011-05-26
RU2010142988A (ru) 2012-05-10
CA2719437A1 (en) 2009-10-08
EP2273997A2 (de) 2011-01-19
WO2009121503A3 (de) 2009-11-26
RU2491076C2 (ru) 2013-08-27
US20110020299A1 (en) 2011-01-27
WO2009121503A2 (de) 2009-10-08
AU2009231139A1 (en) 2009-10-08

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Application publication date: 20110223