JP2011516046A - 肺障害の検出のための多元的方法 - Google Patents

肺障害の検出のための多元的方法 Download PDF

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JP2011516046A
JP2011516046A JP2011502136A JP2011502136A JP2011516046A JP 2011516046 A JP2011516046 A JP 2011516046A JP 2011502136 A JP2011502136 A JP 2011502136A JP 2011502136 A JP2011502136 A JP 2011502136A JP 2011516046 A JP2011516046 A JP 2011516046A
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lung cancer
patient
clinical
cancer
expression
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JP2011516046A5 (enExample
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アブラム スピラ，
マーク イー． レンバーグ，
ジェニファー イー． ビーン−エーベル，
ダニエル リッピー，
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Boston University
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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JP2011502136A 2008-03-28 2009-03-30 肺障害の検出のための多元的方法 Withdrawn JP2011516046A (ja)

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US4043408P 2008-03-28 2008-03-28
US61/040,434 2008-03-28
PCT/US2009/038836 WO2009121070A1 (en) 2008-03-28 2009-03-30 Multifactorial methods for detecting lung disorders

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JP2011516046A true JP2011516046A (ja) 2011-05-26
JP2011516046A5 JP2011516046A5 (enExample) 2013-05-23

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EP (1) EP2268836A4 (enExample)
JP (1) JP2011516046A (enExample)
CA (1) CA2719805A1 (enExample)
WO (1) WO2009121070A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015533477A (ja) * 2012-08-20 2015-11-26 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ 初期段階の肺がんにおける予後指標としてのタンパク質コーディング遺伝子及び非コーディング遺伝子の発現
JP2017215305A (ja) * 2016-05-31 2017-12-07 モル−ヌコ エンタープライジズ, インク.Mor−Nuco Enterprises, Inc. 悪性疾患の臨床症状より最大１０年前に早期がんを検出及びがんを診断するための標的化２次元ウエスタンブロット分析の方法及び組成物
JP2018524972A (ja) * 2015-05-19 2018-09-06 ザ・ウイスター・インステイテユート・オブ・アナトミー・アンド・バイオロジー 肺癌の診断または検出のための方法及び組成物
JP2019532410A (ja) * 2016-09-14 2019-11-07 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 個人の生物学的ステータスを予測するためのシステム、方法および遺伝子シグネチャ

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EP1874962A2 (en) * 2005-04-14 2008-01-09 The Trustees Of Boston University Diagnostic for lung disorders using class prediction
EP2605018A1 (en) * 2006-03-09 2013-06-19 The Trustees of the Boston University Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells
CN101990577A (zh) 2007-09-19 2011-03-23 波士顿大学理事会 鉴定肺病药物开发的新途径
US10236078B2 (en) 2008-11-17 2019-03-19 Veracyte, Inc. Methods for processing or analyzing a sample of thyroid tissue
US9495515B1 (en) 2009-12-09 2016-11-15 Veracyte, Inc. Algorithms for disease diagnostics
JP6078339B2 (ja) 2009-05-07 2017-02-08 ベラサイト インコーポレイテッド 甲状腺状態の診断のための方法および組成物
CN102892897B (zh) * 2009-12-24 2016-08-03 复旦大学 用于肺癌的微rna表达谱分析的组合物和方法
US10526655B2 (en) 2013-03-14 2020-01-07 Veracyte, Inc. Methods for evaluating COPD status
US11976329B2 (en) 2013-03-15 2024-05-07 Veracyte, Inc. Methods and systems for detecting usual interstitial pneumonia
WO2016011068A1 (en) 2014-07-14 2016-01-21 Allegro Diagnostics Corp. Methods for evaluating lung cancer status
US12297505B2 (en) 2014-07-14 2025-05-13 Veracyte, Inc. Algorithms for disease diagnostics
EP3770274A1 (en) 2014-11-05 2021-01-27 Veracyte, Inc. Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data
CN110114680A (zh) * 2016-05-05 2019-08-09 佰欧迪塞克斯公司 用于诊断肺癌的组合物、方法和试剂盒
US10927417B2 (en) 2016-07-08 2021-02-23 Trustees Of Boston University Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions
US10677800B2 (en) * 2016-09-14 2020-06-09 University Of Maryland, Baltimore Biomarkers for diagnosis and prognosis of lung cancer
CN116269239B (zh) * 2023-04-06 2025-12-02 上海交通大学医学院附属瑞金医院 一种双模态复合肿瘤治疗系统

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AU2002250285A1 (en) * 2001-03-14 2002-09-24 Medical College Of Ohio Method for quantitative measurement of gene expression for identifying individuals at risk for bronchogenic carcinoma
AU2002343443A1 (en) * 2001-09-28 2003-04-14 Whitehead Institute For Biomedical Research Classification of lung carcinomas using gene expression analysis
US20040005294A1 (en) * 2002-02-25 2004-01-08 Ho-Young Lee IGFBP-3 in the diagnosis and treatment of cancer
US8722331B2 (en) * 2002-03-28 2014-05-13 University Of Toledo Method for selecting a treatment for non-small cell lung cancer using gene expression profiles
US20040063120A1 (en) * 2002-07-10 2004-04-01 The Regents Of The University Of Michigan Expression profile of lung cancer
WO2004070062A2 (en) * 2003-02-04 2004-08-19 Wyeth Compositions and methods for diagnosing and treating cancers
US20040241725A1 (en) * 2003-03-25 2004-12-02 Wenming Xiao Lung cancer detection
WO2005000098A2 (en) * 2003-06-10 2005-01-06 The Trustees Of Boston University Detection methods for disorders of the lung
WO2005047451A2 (en) * 2003-11-12 2005-05-26 Trustees Of Boston University Isolation of nucleic acid from mouth epithelial cells
EP1753873A4 (en) * 2004-03-05 2008-11-05 Ohio Med College METHOD AND COMPOSITIONS FOR THE ASSESSMENT OF NUCLEIC ACIDS AND ALLELES
US7862995B2 (en) * 2004-12-10 2011-01-04 Targeted Molecular Diagnostics Methods and materials for predicting responsiveness to treatment with dual tyrosine kinase inhibitor
EP1851334A4 (en) * 2005-01-21 2010-05-26 Gene Express Inc DATABASES FOR EVALUATING NUCLEIC ACIDS
EP1874962A2 (en) * 2005-04-14 2008-01-09 The Trustees Of Boston University Diagnostic for lung disorders using class prediction
EP1940860B1 (en) * 2005-09-02 2012-08-08 The University of Toledo Methods for identifying biomarkers useful in diagnosis and/or treatment of biological states
EP2605018A1 (en) * 2006-03-09 2013-06-19 The Trustees of the Boston University Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells
CN101990577A (zh) * 2007-09-19 2011-03-23 波士顿大学理事会 鉴定肺病药物开发的新途径

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015533477A (ja) * 2012-08-20 2015-11-26 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ 初期段階の肺がんにおける予後指標としてのタンパク質コーディング遺伝子及び非コーディング遺伝子の発現
US10047401B2 (en) 2012-08-20 2018-08-14 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Expression protein-coding and noncoding genes as prognostic classifiers in early stage lung cancer
JP2018524972A (ja) * 2015-05-19 2018-09-06 ザ・ウイスター・インステイテユート・オブ・アナトミー・アンド・バイオロジー 肺癌の診断または検出のための方法及び組成物
JP2017215305A (ja) * 2016-05-31 2017-12-07 モル−ヌコ エンタープライジズ, インク.Mor−Nuco Enterprises, Inc. 悪性疾患の臨床症状より最大１０年前に早期がんを検出及びがんを診断するための標的化２次元ウエスタンブロット分析の方法及び組成物
JP2019532410A (ja) * 2016-09-14 2019-11-07 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 個人の生物学的ステータスを予測するためのシステム、方法および遺伝子シグネチャ
JP7022119B2 (ja) 2016-09-14 2022-02-17 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 個人の生物学的ステータスを予測するためのシステム、方法および遺伝子シグネチャ
JP2022062189A (ja) * 2016-09-14 2022-04-19 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 個人の生物学的ステータスを予測するためのシステム、方法および遺伝子シグネチャ
JP7275334B2 (ja) 2016-09-14 2023-05-17 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 個人の生物学的ステータスを予測するためのシステム、方法および遺伝子シグネチャ

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EP2268836A1 (en) 2011-01-05
US20100055689A1 (en) 2010-03-04
EP2268836A4 (en) 2011-08-03
WO2009121070A1 (en) 2009-10-01
CA2719805A1 (en) 2009-10-01

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