JP2011516046A5 - - Google Patents
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- Publication number
- JP2011516046A5 JP2011516046A5 JP2011502136A JP2011502136A JP2011516046A5 JP 2011516046 A5 JP2011516046 A5 JP 2011516046A5 JP 2011502136 A JP2011502136 A JP 2011502136A JP 2011502136 A JP2011502136 A JP 2011502136A JP 2011516046 A5 JP2011516046 A5 JP 2011516046A5
- Authority
- JP
- Japan
- Prior art keywords
- lung cancer
- patient
- expression
- genes
- analysis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims description 99
- 201000005202 lung cancer Diseases 0.000 claims description 99
- 208000020816 lung neoplasm Diseases 0.000 claims description 99
- 238000000034 method Methods 0.000 claims description 47
- 230000014509 gene expression Effects 0.000 claims description 45
- 108090000623 proteins and genes Proteins 0.000 claims description 45
- 238000012360 testing method Methods 0.000 claims description 20
- 239000008280 blood Substances 0.000 claims description 16
- 210000004369 blood Anatomy 0.000 claims description 16
- 206010028980 Neoplasm Diseases 0.000 claims description 11
- 201000011510 cancer Diseases 0.000 claims description 11
- 208000019693 Lung disease Diseases 0.000 claims description 9
- 108700011259 MicroRNAs Proteins 0.000 claims description 8
- 102000004169 proteins and genes Human genes 0.000 claims description 8
- 238000011269 treatment regimen Methods 0.000 claims description 5
- 230000002159 abnormal effect Effects 0.000 claims description 4
- 238000013276 bronchoscopy Methods 0.000 claims description 4
- 238000003745 diagnosis Methods 0.000 claims description 4
- 101000883798 Homo sapiens Probable ATP-dependent RNA helicase DDX53 Proteins 0.000 claims 1
- 102100038236 Probable ATP-dependent RNA helicase DDX53 Human genes 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 238000011285 therapeutic regimen Methods 0.000 claims 1
- 230000000977 initiatory effect Effects 0.000 description 2
- 239000012472 biological sample Substances 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4043408P | 2008-03-28 | 2008-03-28 | |
| US61/040,434 | 2008-03-28 | ||
| PCT/US2009/038836 WO2009121070A1 (en) | 2008-03-28 | 2009-03-30 | Multifactorial methods for detecting lung disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011516046A JP2011516046A (ja) | 2011-05-26 |
| JP2011516046A5 true JP2011516046A5 (enExample) | 2013-05-23 |
Family
ID=41114359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011502136A Withdrawn JP2011516046A (ja) | 2008-03-28 | 2009-03-30 | 肺障害の検出のための多元的方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20100055689A1 (enExample) |
| EP (1) | EP2268836A4 (enExample) |
| JP (1) | JP2011516046A (enExample) |
| CA (1) | CA2719805A1 (enExample) |
| WO (1) | WO2009121070A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1874962A2 (en) * | 2005-04-14 | 2008-01-09 | The Trustees Of Boston University | Diagnostic for lung disorders using class prediction |
| EP2605018A1 (en) * | 2006-03-09 | 2013-06-19 | The Trustees of the Boston University | Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells |
| CN101990577A (zh) | 2007-09-19 | 2011-03-23 | 波士顿大学理事会 | 鉴定肺病药物开发的新途径 |
| US10236078B2 (en) | 2008-11-17 | 2019-03-19 | Veracyte, Inc. | Methods for processing or analyzing a sample of thyroid tissue |
| US9495515B1 (en) | 2009-12-09 | 2016-11-15 | Veracyte, Inc. | Algorithms for disease diagnostics |
| JP6078339B2 (ja) | 2009-05-07 | 2017-02-08 | ベラサイト インコーポレイテッド | 甲状腺状態の診断のための方法および組成物 |
| CN102892897B (zh) * | 2009-12-24 | 2016-08-03 | 复旦大学 | 用于肺癌的微rna表达谱分析的组合物和方法 |
| US10047401B2 (en) | 2012-08-20 | 2018-08-14 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Expression protein-coding and noncoding genes as prognostic classifiers in early stage lung cancer |
| US10526655B2 (en) | 2013-03-14 | 2020-01-07 | Veracyte, Inc. | Methods for evaluating COPD status |
| US11976329B2 (en) | 2013-03-15 | 2024-05-07 | Veracyte, Inc. | Methods and systems for detecting usual interstitial pneumonia |
| WO2016011068A1 (en) | 2014-07-14 | 2016-01-21 | Allegro Diagnostics Corp. | Methods for evaluating lung cancer status |
| US12297505B2 (en) | 2014-07-14 | 2025-05-13 | Veracyte, Inc. | Algorithms for disease diagnostics |
| EP3770274A1 (en) | 2014-11-05 | 2021-01-27 | Veracyte, Inc. | Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data |
| EP3298182A4 (en) * | 2015-05-19 | 2019-01-02 | The Wistar Institute Of Anatomy And Biology | Methods and compositions for diagnosing or detecting lung cancers |
| CN110114680A (zh) * | 2016-05-05 | 2019-08-09 | 佰欧迪塞克斯公司 | 用于诊断肺癌的组合物、方法和试剂盒 |
| US9612243B1 (en) * | 2016-05-31 | 2017-04-04 | Mor-Nuco Enterprises, Inc. | Methods and compositions for targeted two-dimensional western blot analysis for early cancer detection and cancer diagnosis up to ten years in advance of clinical symptoms of malignant disease |
| US10927417B2 (en) | 2016-07-08 | 2021-02-23 | Trustees Of Boston University | Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions |
| KR102421109B1 (ko) * | 2016-09-14 | 2022-07-14 | 필립모리스 프로덕츠 에스.에이. | 개인의 생물학적 상태를 예측하기 위한 시스템, 방법 및 유전자 시그니처 |
| US10677800B2 (en) * | 2016-09-14 | 2020-06-09 | University Of Maryland, Baltimore | Biomarkers for diagnosis and prognosis of lung cancer |
| CN116269239B (zh) * | 2023-04-06 | 2025-12-02 | 上海交通大学医学院附属瑞金医院 | 一种双模态复合肿瘤治疗系统 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3640268A (en) * | 1965-10-23 | 1972-02-08 | Hugh J Davis | Method and device for biopsy specimen collecting and handling |
| US4641662A (en) * | 1984-09-28 | 1987-02-10 | Jaicks John R | Endocervical curette system |
| US4800896A (en) * | 1985-11-08 | 1989-01-31 | Jalowayski Alfredo A | Cell sample collector probe |
| US5422273A (en) * | 1993-03-23 | 1995-06-06 | Baal Medical Products, Inc. | Cell collection apparatus |
| US5477863A (en) * | 1993-04-14 | 1995-12-26 | Grant; Michael A. | Collection kit with a sample collector |
| US5440942A (en) * | 1994-02-02 | 1995-08-15 | Hubbard; Stephen H. | Biological sample collecting and holding device |
| US6085907A (en) * | 1998-05-08 | 2000-07-11 | Institute Of Legal Medicine, University Of Bern | Foldable cardboard box for contact-free drying and long-term storage of biological evidence recovered on cotton swabs and forensic evidence collection kit including same |
| US6746846B1 (en) * | 1999-06-30 | 2004-06-08 | Corixa Corporation | Methods for diagnosing lung cancer |
| IL157872A0 (en) * | 2001-03-12 | 2004-03-28 | Monogen Inc | A panel for detecting a generic disease state containing a plurality of probes and using cell-based diagnosis |
| AU2002250285A1 (en) * | 2001-03-14 | 2002-09-24 | Medical College Of Ohio | Method for quantitative measurement of gene expression for identifying individuals at risk for bronchogenic carcinoma |
| AU2002343443A1 (en) * | 2001-09-28 | 2003-04-14 | Whitehead Institute For Biomedical Research | Classification of lung carcinomas using gene expression analysis |
| US20040005294A1 (en) * | 2002-02-25 | 2004-01-08 | Ho-Young Lee | IGFBP-3 in the diagnosis and treatment of cancer |
| US8722331B2 (en) * | 2002-03-28 | 2014-05-13 | University Of Toledo | Method for selecting a treatment for non-small cell lung cancer using gene expression profiles |
| US20040063120A1 (en) * | 2002-07-10 | 2004-04-01 | The Regents Of The University Of Michigan | Expression profile of lung cancer |
| WO2004070062A2 (en) * | 2003-02-04 | 2004-08-19 | Wyeth | Compositions and methods for diagnosing and treating cancers |
| US20040241725A1 (en) * | 2003-03-25 | 2004-12-02 | Wenming Xiao | Lung cancer detection |
| WO2005000098A2 (en) * | 2003-06-10 | 2005-01-06 | The Trustees Of Boston University | Detection methods for disorders of the lung |
| WO2005047451A2 (en) * | 2003-11-12 | 2005-05-26 | Trustees Of Boston University | Isolation of nucleic acid from mouth epithelial cells |
| EP1753873A4 (en) * | 2004-03-05 | 2008-11-05 | Ohio Med College | METHOD AND COMPOSITIONS FOR THE ASSESSMENT OF NUCLEIC ACIDS AND ALLELES |
| US7862995B2 (en) * | 2004-12-10 | 2011-01-04 | Targeted Molecular Diagnostics | Methods and materials for predicting responsiveness to treatment with dual tyrosine kinase inhibitor |
| EP1851334A4 (en) * | 2005-01-21 | 2010-05-26 | Gene Express Inc | DATABASES FOR EVALUATING NUCLEIC ACIDS |
| EP1874962A2 (en) * | 2005-04-14 | 2008-01-09 | The Trustees Of Boston University | Diagnostic for lung disorders using class prediction |
| EP1940860B1 (en) * | 2005-09-02 | 2012-08-08 | The University of Toledo | Methods for identifying biomarkers useful in diagnosis and/or treatment of biological states |
| EP2605018A1 (en) * | 2006-03-09 | 2013-06-19 | The Trustees of the Boston University | Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells |
| CN101990577A (zh) * | 2007-09-19 | 2011-03-23 | 波士顿大学理事会 | 鉴定肺病药物开发的新途径 |
-
2009
- 2009-03-30 WO PCT/US2009/038836 patent/WO2009121070A1/en not_active Ceased
- 2009-03-30 CA CA2719805A patent/CA2719805A1/en not_active Abandoned
- 2009-03-30 US US12/414,555 patent/US20100055689A1/en not_active Abandoned
- 2009-03-30 JP JP2011502136A patent/JP2011516046A/ja not_active Withdrawn
- 2009-03-30 EP EP09724548A patent/EP2268836A4/en not_active Withdrawn
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