JP2015502541A5 - - Google Patents
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- Publication number
- JP2015502541A5 JP2015502541A5 JP2014543889A JP2014543889A JP2015502541A5 JP 2015502541 A5 JP2015502541 A5 JP 2015502541A5 JP 2014543889 A JP2014543889 A JP 2014543889A JP 2014543889 A JP2014543889 A JP 2014543889A JP 2015502541 A5 JP2015502541 A5 JP 2015502541A5
- Authority
- JP
- Japan
- Prior art keywords
- pancreatic cancer
- subject
- biomarker
- sample
- ceramide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims description 32
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims description 32
- 238000000034 method Methods 0.000 claims description 32
- 201000002528 pancreatic cancer Diseases 0.000 claims description 32
- 208000008443 pancreatic carcinoma Diseases 0.000 claims description 32
- 239000000090 biomarker Substances 0.000 claims description 29
- 206010033645 Pancreatitis Diseases 0.000 claims description 7
- 238000011156 evaluation Methods 0.000 claims description 5
- 210000002381 plasma Anatomy 0.000 claims description 5
- 206010016654 Fibrosis Diseases 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 230000007882 cirrhosis Effects 0.000 claims description 4
- 208000019425 cirrhosis of liver Diseases 0.000 claims description 4
- 238000001514 detection method Methods 0.000 claims description 4
- 206010052747 Adenocarcinoma pancreas Diseases 0.000 claims description 3
- 238000003745 diagnosis Methods 0.000 claims description 3
- 201000002094 pancreatic adenocarcinoma Diseases 0.000 claims description 3
- 208000016222 Pancreatic disease Diseases 0.000 claims description 2
- 238000002651 drug therapy Methods 0.000 claims description 2
- 238000001959 radiotherapy Methods 0.000 claims description 2
- 210000002966 serum Anatomy 0.000 claims description 2
- 238000001356 surgical procedure Methods 0.000 claims description 2
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 claims 6
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 claims 6
- 229940106189 ceramide Drugs 0.000 claims 6
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 claims 6
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 claims 6
- 239000012491 analyte Substances 0.000 claims 1
- 208000000668 Chronic Pancreatitis Diseases 0.000 description 1
- 206010033649 Pancreatitis chronic Diseases 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161564891P | 2011-11-30 | 2011-11-30 | |
| EP11191365.3 | 2011-11-30 | ||
| US61/564,891 | 2011-11-30 | ||
| EP11191365 | 2011-11-30 | ||
| PCT/EP2012/073965 WO2013079594A1 (en) | 2011-11-30 | 2012-11-29 | Device and methods to diagnose pancreatic cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017185522A Division JP2018049016A (ja) | 2011-11-30 | 2017-09-27 | 膵臓癌を診断するための装置及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015502541A JP2015502541A (ja) | 2015-01-22 |
| JP2015502541A5 true JP2015502541A5 (enExample) | 2016-01-28 |
| JP6219300B2 JP6219300B2 (ja) | 2017-10-25 |
Family
ID=48534696
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014543889A Expired - Fee Related JP6219300B2 (ja) | 2011-11-30 | 2012-11-29 | 膵臓癌を診断するための装置及び方法 |
| JP2017185522A Ceased JP2018049016A (ja) | 2011-11-30 | 2017-09-27 | 膵臓癌を診断するための装置及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017185522A Ceased JP2018049016A (ja) | 2011-11-30 | 2017-09-27 | 膵臓癌を診断するための装置及び方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20140323352A1 (enExample) |
| EP (2) | EP3486657A3 (enExample) |
| JP (2) | JP6219300B2 (enExample) |
| AU (2) | AU2012343843B2 (enExample) |
| CA (1) | CA2857401A1 (enExample) |
| WO (1) | WO2013079594A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014084290A1 (ja) | 2012-11-27 | 2014-06-05 | 味の素株式会社 | 膵臓癌の評価方法、膵臓癌評価装置、膵臓癌評価方法、膵臓癌評価プログラム、膵臓癌評価システムおよび情報通信端末装置 |
| CA2934012A1 (en) * | 2013-12-20 | 2015-06-25 | Metanomics Health Gmbh | Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel |
| US10386359B2 (en) * | 2014-05-23 | 2019-08-20 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods for determining whether a patient will achieve a response after radiation therapy |
| WO2016034600A1 (en) * | 2014-09-01 | 2016-03-10 | Metanomics Gmbh | Means and methods for diagnosing heart failure in a subject |
| AU2016282362A1 (en) | 2015-06-25 | 2018-01-18 | Metanomics Health Gmbh | Means and methods for diagnosing pancreatic cancer in a subject based on a biomarker panel |
| US20180238914A1 (en) * | 2015-08-19 | 2018-08-23 | Metanomics Gmbh | Means and methods for diagnosing cardiac disease in a subject |
| KR102427924B1 (ko) * | 2016-10-04 | 2022-08-02 | 아지노모토 가부시키가이샤 | 췌장암의 평가 방법, 평가 장치, 평가 프로그램, 평가 시스템, 및 단말 장치 |
| CN110121647A (zh) * | 2016-12-15 | 2019-08-13 | 得克萨斯大学体系董事会 | 用于检测和治疗胰腺导管腺癌的方法 |
| EP3502699A1 (en) | 2017-12-20 | 2019-06-26 | Metanomics Health GmbH | Methods for diagnosing pancreatic cancer |
| BR112021003477A2 (pt) * | 2018-06-14 | 2021-05-18 | Metabolomycs, Inc. | assinaturas metabolômicas para prever, diagnosticar e prognosticar várias doenças incluindo câncer |
| KR102070916B1 (ko) * | 2018-08-31 | 2020-01-29 | 연세대학교 산학협력단 | 췌장암 환자의 예후를 예측하기 위한 바이오마커 및 이의 용도 |
| KR102239206B1 (ko) * | 2019-03-06 | 2021-04-12 | 연세대학교 산학협력단 | 절제술 효과 평가 장치 및 시스템 |
| ES2799973A1 (es) * | 2019-06-19 | 2020-12-22 | Univ Granada | Panel de metabolitos como biomarcadores para el diagnostico de cancer de pancreas |
| WO2022140380A1 (en) * | 2020-12-21 | 2022-06-30 | Pancreomics Llc | Metabolomic signatures for predicting, diagnosing, and prognosing chronic pancreatitis |
| CN113655142B (zh) * | 2021-08-09 | 2023-11-10 | 大连医科大学附属第一医院 | 一种基于磷脂酰丝氨酸和磷脂酰乙醇胺的早期预警重症急性胰腺炎的模型与应用 |
| CN114371239B (zh) * | 2022-03-22 | 2022-07-15 | 长沙都正医学检验有限责任公司 | 用于测定氧化三甲胺的试剂盒及其制备方法和应用 |
| TWI859033B (zh) | 2023-12-18 | 2024-10-11 | 安益藥業股份有限公司 | 一種診斷犬科動物胰臟炎的方法與試劑組與一種使用醯基肉鹼作為診斷犬科動物胰臟炎之用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4540884A (en) | 1982-12-29 | 1985-09-10 | Finnigan Corporation | Method of mass analyzing a sample by use of a quadrupole ion trap |
| JPH02128697A (ja) * | 1988-11-09 | 1990-05-17 | Hoechst Japan Ltd | 抗フコシルセラミドモノクローナル抗体 |
| US6083929A (en) * | 1991-05-06 | 2000-07-04 | The Biomembrane Institute | Extended type 1 chain glycosphingolipids as tumor-associated antigens |
| US5397894A (en) | 1993-05-28 | 1995-03-14 | Varian Associates, Inc. | Method of high mass resolution scanning of an ion trap mass spectrometer |
| US7196323B2 (en) | 2002-02-28 | 2007-03-27 | Metanomics Gmbh & Co. Kgaa | Mass spectrometry method for analyzing mixtures of substances |
| EP1561471A1 (en) * | 2002-10-11 | 2005-08-10 | Chugai Seiyaku Kabushiki Kaisha | Cell growth regulator |
| EP2770328B1 (en) * | 2009-10-01 | 2017-12-27 | Phenomenome Discoveries Inc. | Method to diagnose pancreatic cancer |
| CA2800023A1 (en) * | 2010-06-01 | 2011-12-08 | Metanomics Health Gmbh | Means and methods for diagnosing pancreatic cancer in a subject |
| AU2011270968C1 (en) * | 2010-06-23 | 2017-01-19 | University Of Louisville Research Foundation, Inc. | Methods for detecting cancer |
| US20140148350A1 (en) * | 2010-08-18 | 2014-05-29 | David Spetzler | Circulating biomarkers for disease |
| CN105572276B (zh) * | 2014-11-07 | 2018-12-18 | 上海市第六人民医院 | 胰腺癌诊断标记物组合、应用及其测定方法 |
-
2012
- 2012-11-29 WO PCT/EP2012/073965 patent/WO2013079594A1/en not_active Ceased
- 2012-11-29 EP EP18215709.9A patent/EP3486657A3/en not_active Withdrawn
- 2012-11-29 EP EP12799110.7A patent/EP2786152B1/en active Active
- 2012-11-29 JP JP2014543889A patent/JP6219300B2/ja not_active Expired - Fee Related
- 2012-11-29 US US14/361,460 patent/US20140323352A1/en not_active Abandoned
- 2012-11-29 AU AU2012343843A patent/AU2012343843B2/en not_active Ceased
- 2012-11-29 CA CA2857401A patent/CA2857401A1/en not_active Abandoned
-
2017
- 2017-09-27 JP JP2017185522A patent/JP2018049016A/ja not_active Ceased
-
2018
- 2018-06-04 AU AU2018203939A patent/AU2018203939A1/en not_active Abandoned
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