JP2011509156A - 血管移植片の開存性を促進するための組成物および方法 - Google Patents

血管移植片の開存性を促進するための組成物および方法 Download PDF

Info

Publication number
JP2011509156A
JP2011509156A JP2010542335A JP2010542335A JP2011509156A JP 2011509156 A JP2011509156 A JP 2011509156A JP 2010542335 A JP2010542335 A JP 2010542335A JP 2010542335 A JP2010542335 A JP 2010542335A JP 2011509156 A JP2011509156 A JP 2011509156A
Authority
JP
Japan
Prior art keywords
polymer
vascular graft
poly
graft
conduit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010542335A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011509156A5 (enExample
Inventor
クリストファー ブレウアー,
セミス キリアキデス,
ジェイソン ロー,
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Original Assignee
Yale University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yale University filed Critical Yale University
Publication of JP2011509156A publication Critical patent/JP2011509156A/ja
Publication of JP2011509156A5 publication Critical patent/JP2011509156A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/195Chemokines, e.g. RANTES
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/426Immunomodulating agents, i.e. cytokines, interleukins, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602Type of release, e.g. controlled, sustained, slow
    • A61L2300/604Biodegradation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Polymers & Plastics (AREA)
JP2010542335A 2008-01-08 2009-01-08 血管移植片の開存性を促進するための組成物および方法 Pending JP2011509156A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1040608P 2008-01-08 2008-01-08
PCT/US2009/030407 WO2009089324A1 (en) 2008-01-08 2009-01-08 Compositions and methods for promoting patency of vascular grafts

Publications (2)

Publication Number Publication Date
JP2011509156A true JP2011509156A (ja) 2011-03-24
JP2011509156A5 JP2011509156A5 (enExample) 2013-02-21

Family

ID=40352092

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010542335A Pending JP2011509156A (ja) 2008-01-08 2009-01-08 血管移植片の開存性を促進するための組成物および方法

Country Status (3)

Country Link
US (3) US9855370B2 (enExample)
JP (1) JP2011509156A (enExample)
WO (1) WO2009089324A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009089324A1 (en) 2008-01-08 2009-07-16 Yale University Compositions and methods for promoting patency of vascular grafts
WO2013003157A1 (en) * 2011-06-28 2013-01-03 Yale University Cell-free tissued engineered vascular grafts
US10195252B2 (en) 2012-08-03 2019-02-05 University of Pittsburgh—of the Commonwealth System of Higher Education Recruitment of mensenchymal cells using controlled release systems
WO2015148775A1 (en) * 2014-03-27 2015-10-01 Board Of Regents, The University Of Texas System Compositions and methods for growing autologous biological tissue
WO2017100782A1 (en) * 2015-12-11 2017-06-15 Research Institute At Nationwide Children's Hospital Systems and methods for optimized patent specific tissue engineering vascular grafts
US20200054790A1 (en) * 2017-05-02 2020-02-20 The Johns Hopkins University Implantable vascular grafts
JP2023503256A (ja) * 2019-11-15 2023-01-27 リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル 播種されたグラフトを生成するシステムおよび方法
CN119454907A (zh) * 2025-01-09 2025-02-18 浙江大学 Vegf-c156s在制备减轻静脉移植物狭窄的药物中的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003506401A (ja) * 1999-08-06 2003-02-18 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム 薬剤放出生分解性繊維インプラント
US20030082148A1 (en) * 2001-10-31 2003-05-01 Florian Ludwig Methods and device compositions for the recruitment of cells to blood contacting surfaces in vivo
WO2007059253A2 (en) * 2005-11-15 2007-05-24 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459128A (en) * 1993-11-12 1995-10-17 Dana-Farber Cancer Institute Human monocyte chemoattractant protein-1 (MCP-1) derivatives
US5716394A (en) 1994-04-29 1998-02-10 W. L. Gore & Associates, Inc. Blood contact surfaces using extracellular matrix synthesized in vitro
US6774278B1 (en) 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
US5922554A (en) 1995-10-30 1999-07-13 The Regents Of The University Of California Inhibition of cellular uptake of cholesterol
WO1997028262A1 (en) 1996-02-01 1997-08-07 University Of Florida Lyst1 and lyst2 gene compositions and methods of use
GB9716657D0 (en) * 1997-08-07 1997-10-15 Zeneca Ltd Chemical compounds
CA2325562A1 (en) 1998-04-03 1999-10-14 Curagen Corporation Lyst protein complexes and lyst interacting proteins
US6984400B2 (en) 1998-07-14 2006-01-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method of treating restenosis using bisphosphonate nanoparticles
US7008645B2 (en) 1998-07-14 2006-03-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method of inhibiting restenosis using bisphosphonates
US6184226B1 (en) 1998-08-28 2001-02-06 Scios Inc. Quinazoline derivatives as inhibitors of P-38 α
FR2785812B1 (fr) * 1998-11-16 2002-11-29 Commissariat Energie Atomique Protheses bioactives, notamment a proprietes immunosuppressives, antistenose et antithrombose, et leur fabrication
US7763580B2 (en) 1999-01-05 2010-07-27 University Of Utah Research Foundation Methods for treating conditions associated with the accumulation of excess extracellular matrix
GB9902455D0 (en) * 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
DE60001229T2 (de) 1999-04-09 2003-10-30 Smithkline Beecham Corp., Philadelphia Triarylimidazole
US20020125613A1 (en) 2001-03-08 2002-09-12 Cominsky Kenneth D. Mandrel fabrication for cobond assembly
US6660034B1 (en) * 2001-04-30 2003-12-09 Advanced Cardiovascular Systems, Inc. Stent for increasing blood flow to ischemic tissues and a method of using the same
WO2002102432A1 (en) 2001-06-15 2002-12-27 Johns Hopkins Singapore Pte Ltd Biofunctional fibers
US20030064965A1 (en) 2001-10-02 2003-04-03 Jacob Richter Method of delivering drugs to a tissue using drug-coated medical devices
NZ532593A (en) 2001-10-25 2007-11-30 Wisconsin Alumni Res Found Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and method of using same
US20040063654A1 (en) 2001-11-02 2004-04-01 Davis Mark E. Methods and compositions for therapeutic use of RNA interference
GB0217786D0 (en) 2002-07-31 2002-09-11 Glaxo Group Ltd Compounds
US20050163821A1 (en) * 2002-08-02 2005-07-28 Hsing-Wen Sung Drug-eluting Biodegradable Stent and Delivery Means
EP1542724A4 (en) * 2002-08-19 2005-10-19 Abgenix Inc ANTIBODIES AGAINST THE MONOCYTE 1 CHIMIOATTRACTIVE PROTEIN (MCP-1) AND USES THEREOF
AU2003290734A1 (en) 2002-11-27 2004-06-23 Eli Lilly And Company Novel compounds as pharmaceutical agents
WO2004073504A2 (en) * 2003-02-20 2004-09-02 Proteon Therapeutics, Llc Methods for the treatment and prevention of diseases of biological conduits
MXPA05009245A (es) 2003-03-11 2005-10-19 Pfizer Prod Inc Nuevos compuestos de pirazina como inhibidores del factor de crecimiento transformante (tgf).
US7314939B2 (en) 2003-06-17 2008-01-01 Millennium Pharmaceuticals, Inc. Compositions and methods for inhibiting TGF-β
WO2005013915A2 (en) 2003-08-08 2005-02-17 The Regents Of The University Of California Novel indications for transforming growth factor-beta regulators
DE502004005857D1 (de) 2003-09-29 2008-02-14 Hemoteq Ag Biokompatible, biostabile beschichtung von medizinischen oberflächen
WO2005049105A2 (en) * 2003-11-10 2005-06-02 Angiotech International Ag Medical implants and anti-scarring agents
US6997989B2 (en) * 2003-12-08 2006-02-14 Boston Scientific Scimed, Inc. Medical implant processing chamber
PT1699915E (pt) * 2003-12-30 2010-08-31 Augustinus Bader Utilização de eritropoietina para a regeneração de tecido hepático
ATE464855T1 (de) 2004-03-31 2010-05-15 Cook Inc Transplantatmaterial und gefässprothese mit extrazellulärer kollagenmatrix und dessen herstellungsverfahren
US7763065B2 (en) 2004-07-21 2010-07-27 Reva Medical, Inc. Balloon expandable crush-recoverable stent device
JP5144000B2 (ja) 2004-08-25 2013-02-13 太陽化学株式会社 形質転換増殖因子β抑制用組成物
CA2578630A1 (en) 2004-08-31 2006-03-09 Wen-Cherng Lee Pyrimidinylimidazoles as tgf-beta inhibitors
US8728463B2 (en) * 2005-03-11 2014-05-20 Wake Forest University Health Science Production of tissue engineered digits and limbs
US20060217437A1 (en) 2005-03-17 2006-09-28 Burmester James K TGF-beta modulators and methods for using the same
US20110301098A1 (en) 2006-07-21 2011-12-08 Quax Paul H A Treatment for intimal hyperplasia and related conditions
WO2008039521A2 (en) * 2006-09-26 2008-04-03 Nmt Medical, Inc. Method for modifying a medical implant surface for promoting tissue growth
CN101528752A (zh) 2006-10-16 2009-09-09 辉瑞产品公司 治疗性吡唑基噻吩并吡啶
US7959942B2 (en) 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating
KR20090122202A (ko) 2007-01-30 2009-11-26 헤모텍 아게 생분해성 혈관 지지체
KR100932688B1 (ko) 2007-07-06 2009-12-21 한국과학기술연구원 인공혈관용 이중막 구조의 튜브형 다공성 스캐폴드 및 그의제조방법
US20090043378A1 (en) * 2007-08-10 2009-02-12 Medtronic Vascular, Inc. Biocompatible Polymer System for Extended Drug Release
US8277832B2 (en) 2007-10-10 2012-10-02 The University Of Kansas Microsphere-based materials with predefined 3D spatial and temporal control of biomaterials, porosity and/or bioactive signals
US7824601B1 (en) 2007-11-14 2010-11-02 Abbott Cardiovascular Systems Inc. Process of making a tubular implantable medical device
WO2009089324A1 (en) 2008-01-08 2009-07-16 Yale University Compositions and methods for promoting patency of vascular grafts
US20100092534A1 (en) * 2008-10-10 2010-04-15 Medtronic Vascular, Inc. Combination Local Delivery Using a Stent
US20100129414A1 (en) 2008-11-24 2010-05-27 Medtronic Vascular, Inc. Bioactive Agent Delivery Using Liposomes in Conjunction With Stent Deployment
AU2010353739B2 (en) 2010-05-17 2014-03-27 Pall Corporation System for seeding cells onto three dimensional scaffolds
RU2440128C1 (ru) 2010-05-17 2012-01-20 Государственное образовательное учреждение дополнительного профессионального образования "Санкт-Петербургская медицинская академия последипломного образования Федерального агентства по здравоохранению и социальному развитию" (ГОУ ДПО СПбМАПО Росздрава) Способ комплексной патогенетической терапии острых форм вирусного гепатита в и микст-гепатитов (в+с, в+d, в+с+d)
US9090863B2 (en) 2010-05-17 2015-07-28 Pall Corporation System for seeding cells onto three dimensional scaffolds
US20130013083A1 (en) 2011-01-06 2013-01-10 Humacyte Tissue-Engineered Constructs
US10227568B2 (en) 2011-03-22 2019-03-12 Nanofiber Solutions, Llc Fiber scaffolds for use in esophageal prostheses
WO2013003157A1 (en) 2011-06-28 2013-01-03 Yale University Cell-free tissued engineered vascular grafts
EP2971318B1 (en) 2013-03-15 2021-07-21 Nanofiber Solutions, LLC Biocompatible fiber textiles for implantation
WO2014197790A1 (en) 2013-06-06 2014-12-11 University Of Maryland, College Park Compositions and methods for making biodegradable structures
WO2017100782A1 (en) 2015-12-11 2017-06-15 Research Institute At Nationwide Children's Hospital Systems and methods for optimized patent specific tissue engineering vascular grafts

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003506401A (ja) * 1999-08-06 2003-02-18 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム 薬剤放出生分解性繊維インプラント
US20030082148A1 (en) * 2001-10-31 2003-05-01 Florian Ludwig Methods and device compositions for the recruitment of cells to blood contacting surfaces in vivo
WO2007059253A2 (en) * 2005-11-15 2007-05-24 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6013035706; J. Pediatric Surgery, 2007, Vol.42, pp.198-202 *

Also Published As

Publication number Publication date
US20220226542A1 (en) 2022-07-21
US9855370B2 (en) 2018-01-02
US20100303889A1 (en) 2010-12-02
WO2009089324A1 (en) 2009-07-16
US20180193529A1 (en) 2018-07-12
US12186455B2 (en) 2025-01-07

Similar Documents

Publication Publication Date Title
US12186455B2 (en) Compositions and methods for promoting patency of vascular grafts
US11938246B2 (en) Tissue-based compositions and methods of use thereof
Mrówczyński et al. Porcine carotid artery replacement with biodegradable electrospun poly-e-caprolactone vascular prosthesis
US7794706B2 (en) Bioactive wound dressings and implantable devices and methods of use
US8529961B2 (en) Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
CN100455275C (zh) 包覆有可促进内皮细胞的黏附和分化的包衣的医疗装置
AU2008279578B2 (en) Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
US20120003193A1 (en) Methods and Apparatus for Manufacturing Plasma Based Plastics and Bioplastics Produced Therefrom
JP2008518666A (ja) 生物活性創傷包帯および移植可能な装置ならびに使用法
JP2015532845A (ja) 心臓修復パッチの新しいスキャフォールド
Fukunishi et al. Nanofiber composites in vascular tissue engineering
Yang et al. VEGF combined with DAPT promotes tissue regeneration and remodeling in vascular grafts
CN106620897B (zh) 一种抗再狭窄的管腔内支架材料
Sugiura et al. Tissue engineering in vascular medicine
CN1649620A (zh) 医疗装置
JP2023503256A (ja) 播種されたグラフトを生成するシステムおよび方法
Vu Biomaterial-Mediated Immunomodulation Via The Implantation of Drug-Eluting Vascular Grafts
US9662417B2 (en) Medical device
JP2015112262A (ja) 組織修復及び/又は再生促進材
Goins Engineering a Biomimetic Scaffold for Small Diameter Blood Vessel Tissue Engineering

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120106

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20120106

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20121219

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130719

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20131218