JP2011508059A5 - - Google Patents
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- Publication number
- JP2011508059A5 JP2011508059A5 JP2010540781A JP2010540781A JP2011508059A5 JP 2011508059 A5 JP2011508059 A5 JP 2011508059A5 JP 2010540781 A JP2010540781 A JP 2010540781A JP 2010540781 A JP2010540781 A JP 2010540781A JP 2011508059 A5 JP2011508059 A5 JP 2011508059A5
- Authority
- JP
- Japan
- Prior art keywords
- medical device
- group
- hydrophilic
- monomer
- silicon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 31
- 239000000178 monomer Substances 0.000 claims 17
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 10
- 229920001400 block copolymer Polymers 0.000 claims 10
- 229910052710 silicon Inorganic materials 0.000 claims 10
- 239000010703 silicon Substances 0.000 claims 10
- 239000003607 modifier Substances 0.000 claims 9
- -1 polydimethylsiloxane Polymers 0.000 claims 9
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 7
- 125000000524 functional group Chemical group 0.000 claims 5
- 150000001299 aldehydes Chemical class 0.000 claims 4
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 3
- PEEHTFAAVSWFBL-UHFFFAOYSA-N Maleimide Chemical compound O=C1NC(=O)C=C1 PEEHTFAAVSWFBL-UHFFFAOYSA-N 0.000 claims 3
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 3
- 239000000017 hydrogel Substances 0.000 claims 3
- 150000002576 ketones Chemical class 0.000 claims 3
- 239000000463 material Substances 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- VAYTZRYEBVHVLE-UHFFFAOYSA-N 1,3-dioxol-2-one Chemical compound O=C1OC=CO1 VAYTZRYEBVHVLE-UHFFFAOYSA-N 0.000 claims 2
- KCOPAESEGCGTKM-UHFFFAOYSA-N 1,3-oxazol-4-one Chemical compound O=C1COC=N1 KCOPAESEGCGTKM-UHFFFAOYSA-N 0.000 claims 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 2
- BWGNESOTFCXPMA-UHFFFAOYSA-N Dihydrogen disulfide Chemical compound SS BWGNESOTFCXPMA-UHFFFAOYSA-N 0.000 claims 2
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 claims 2
- 241001061127 Thione Species 0.000 claims 2
- 150000008065 acid anhydrides Chemical class 0.000 claims 2
- 125000003342 alkenyl group Chemical group 0.000 claims 2
- 150000001412 amines Chemical class 0.000 claims 2
- 238000010560 atom transfer radical polymerization reaction Methods 0.000 claims 2
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims 2
- 150000001733 carboxylic acid esters Chemical class 0.000 claims 2
- 238000006243 chemical reaction Methods 0.000 claims 2
- 150000002118 epoxides Chemical class 0.000 claims 2
- 239000007943 implant Substances 0.000 claims 2
- 239000003999 initiator Substances 0.000 claims 2
- 239000012948 isocyanate Substances 0.000 claims 2
- 150000002513 isocyanates Chemical class 0.000 claims 2
- 150000002540 isothiocyanates Chemical class 0.000 claims 2
- 150000003951 lactams Chemical class 0.000 claims 2
- 150000002596 lactones Chemical class 0.000 claims 2
- GASFVSRUEBGMDI-UHFFFAOYSA-N n-aminohydroxylamine Chemical compound NNO GASFVSRUEBGMDI-UHFFFAOYSA-N 0.000 claims 2
- 230000000269 nucleophilic effect Effects 0.000 claims 2
- 150000002905 orthoesters Chemical class 0.000 claims 2
- PTMHPRAIXMAOOB-UHFFFAOYSA-L phosphoramidate Chemical compound NP([O-])([O-])=O PTMHPRAIXMAOOB-UHFFFAOYSA-L 0.000 claims 2
- 229920001296 polysiloxane Polymers 0.000 claims 2
- 229910000077 silane Inorganic materials 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 150000003457 sulfones Chemical class 0.000 claims 2
- WMGWLIAIMDFMIQ-UHFFFAOYSA-N sulfuroiodidic acid Chemical compound OS(I)(=O)=O WMGWLIAIMDFMIQ-UHFFFAOYSA-N 0.000 claims 2
- 150000003573 thiols Chemical class 0.000 claims 2
- GWIKYPMLNBTJHR-UHFFFAOYSA-M thiosulfonate group Chemical group S(=S)(=O)[O-] GWIKYPMLNBTJHR-UHFFFAOYSA-M 0.000 claims 2
- LVLANIHJQRZTPY-UHFFFAOYSA-N vinyl carbamate Chemical compound NC(=O)OC=C LVLANIHJQRZTPY-UHFFFAOYSA-N 0.000 claims 2
- ZJIFDEVVTPEXDL-UHFFFAOYSA-N (2,5-dioxopyrrolidin-1-yl) hydrogen carbonate Chemical compound OC(=O)ON1C(=O)CCC1=O ZJIFDEVVTPEXDL-UHFFFAOYSA-N 0.000 claims 1
- QRIMLDXJAPZHJE-UHFFFAOYSA-N 2,3-dihydroxypropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCC(O)CO QRIMLDXJAPZHJE-UHFFFAOYSA-N 0.000 claims 1
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 1
- OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical compound OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 claims 1
- BTBWSRPRAGXJJV-UHFFFAOYSA-N 2h-benzotriazole;carbonic acid Chemical compound OC(O)=O.C1=CC=C2NN=NC2=C1 BTBWSRPRAGXJJV-UHFFFAOYSA-N 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims 1
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical group CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 claims 1
- 125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 claims 1
- 125000003158 alcohol group Chemical group 0.000 claims 1
- HAXFWIACAGNFHA-UHFFFAOYSA-N aldrithiol Chemical compound C=1C=CC=NC=1SSC1=CC=CC=N1 HAXFWIACAGNFHA-UHFFFAOYSA-N 0.000 claims 1
- ACBQROXDOHKANW-UHFFFAOYSA-N bis(4-nitrophenyl) carbonate Chemical compound C1=CC([N+](=O)[O-])=CC=C1OC(=O)OC1=CC=C([N+]([O-])=O)C=C1 ACBQROXDOHKANW-UHFFFAOYSA-N 0.000 claims 1
- 210000004204 blood vessel Anatomy 0.000 claims 1
- 210000000481 breast Anatomy 0.000 claims 1
- 239000007795 chemical reaction product Substances 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- GYZLOYUZLJXAJU-UHFFFAOYSA-N diglycidyl ether Chemical compound C1OC1COCC1CO1 GYZLOYUZLJXAJU-UHFFFAOYSA-N 0.000 claims 1
- 239000004205 dimethyl polysiloxane Substances 0.000 claims 1
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 210000003709 heart valve Anatomy 0.000 claims 1
- 150000002373 hemiacetals Chemical class 0.000 claims 1
- FQPSGWSUVKBHSU-UHFFFAOYSA-N methacrylamide Chemical compound CC(=C)C(N)=O FQPSGWSUVKBHSU-UHFFFAOYSA-N 0.000 claims 1
- WFKDPJRCBCBQNT-UHFFFAOYSA-N n,2-dimethylprop-2-enamide Chemical compound CNC(=O)C(C)=C WFKDPJRCBCBQNT-UHFFFAOYSA-N 0.000 claims 1
- RQAKESSLMFZVMC-UHFFFAOYSA-N n-ethenylacetamide Chemical compound CC(=O)NC=C RQAKESSLMFZVMC-UHFFFAOYSA-N 0.000 claims 1
- 125000005375 organosiloxane group Chemical group 0.000 claims 1
- 229920000233 poly(alkylene oxides) Polymers 0.000 claims 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 230000009257 reactivity Effects 0.000 claims 1
- 239000011550 stock solution Substances 0.000 claims 1
- 150000003555 thioacetals Chemical class 0.000 claims 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 1
- 210000000626 ureter Anatomy 0.000 claims 1
- 230000002792 vascular Effects 0.000 claims 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1684507P | 2007-12-27 | 2007-12-27 | |
| US12/334,618 US7942929B2 (en) | 2007-12-27 | 2008-12-15 | Coating solutions comprising segmented reactive block copolymers |
| PCT/US2008/086989 WO2009085755A1 (en) | 2007-12-27 | 2008-12-16 | Coating solutions comprising segmented reactive block copolymers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011508059A JP2011508059A (ja) | 2011-03-10 |
| JP2011508059A5 true JP2011508059A5 (enExample) | 2012-02-09 |
Family
ID=40288871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010540781A Pending JP2011508059A (ja) | 2007-12-27 | 2008-12-16 | セグメント化反応性ブロックコポリマーを含むコーティング溶液 |
Country Status (4)
| Country | Link |
|---|---|
| EP (2) | EP2235094A1 (enExample) |
| JP (1) | JP2011508059A (enExample) |
| CN (1) | CN101977972B (enExample) |
| WO (1) | WO2009085755A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9522980B2 (en) | 2010-05-06 | 2016-12-20 | Johnson & Johnson Vision Care, Inc. | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same |
| US20130203813A1 (en) | 2011-05-04 | 2013-08-08 | Johnson & Johnson Vision Care, Inc. | Medical devices having homogeneous charge density and methods for making same |
| US9170349B2 (en) | 2011-05-04 | 2015-10-27 | Johnson & Johnson Vision Care, Inc. | Medical devices having homogeneous charge density and methods for making same |
| US9505184B2 (en) * | 2011-11-15 | 2016-11-29 | Novartis Ag | Silicone hydrogel lens with a crosslinked hydrophilic coating |
| JP2015526745A (ja) * | 2012-05-25 | 2015-09-10 | ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッドＪｏｈｎｓｏｎ ＆ Ｊｏｈｎｓｏｎ Ｖｉｓｉｏｎ Ｃａｒｅ， Ｉｎｃ． | 水溶性ｎ−（２ヒドロキシアルキル）（メタ）アクリルアミドポリマー又はコポリマーを含むコンタクトレンズ |
| US9297929B2 (en) | 2012-05-25 | 2016-03-29 | Johnson & Johnson Vision Care, Inc. | Contact lenses comprising water soluble N-(2 hydroxyalkyl) (meth)acrylamide polymers or copolymers |
| US9244196B2 (en) | 2012-05-25 | 2016-01-26 | Johnson & Johnson Vision Care, Inc. | Polymers and nanogel materials and methods for making and using the same |
| US10073192B2 (en) | 2012-05-25 | 2018-09-11 | Johnson & Johnson Vision Care, Inc. | Polymers and nanogel materials and methods for making and using the same |
| US9486311B2 (en) | 2013-02-14 | 2016-11-08 | Shifamed Holdings, Llc | Hydrophilic AIOL with bonding |
| US10195018B2 (en) | 2013-03-21 | 2019-02-05 | Shifamed Holdings, Llc | Accommodating intraocular lens |
| AU2014236688B2 (en) | 2013-03-21 | 2019-07-25 | Shifamed Holdings, Llc | Accommodating intraocular lens |
| CA2930552C (en) * | 2013-11-15 | 2022-12-13 | Ocular Dynamics, Llc | Contact lens with a hydrophilic layer |
| AU2015306613B2 (en) | 2014-08-26 | 2018-01-25 | Shifamed Holdings, Llc | Accommodating intraocular lens |
| CN104844746B (zh) * | 2015-05-05 | 2017-03-29 | 南开大学 | 一种具有多重刺激响应性的水溶性聚合物及其制备方法 |
| FR3038903B1 (fr) * | 2015-07-17 | 2019-05-24 | Universite Du Mans | Compose polyurethane ignifuge comprenant des elements oligomeres phosphores de longueur controlee |
| HK1251302A1 (zh) | 2015-10-07 | 2019-01-25 | 株式会社实瞳 | 非含水性眼用镜片的制造方法和非含水性眼用镜片 |
| FR3042794B1 (fr) * | 2015-10-23 | 2020-03-27 | Arkema France | Procede permettant la creation de structures nanometriques par l'auto-assemblage de copolymeres di-blocs |
| CN108472129B (zh) | 2015-11-18 | 2021-09-24 | 施菲姆德控股有限责任公司 | 组合的调节性人工晶状体 |
| US11141263B2 (en) | 2015-11-18 | 2021-10-12 | Shifamed Holdings, Llc | Multi-piece accommodating intraocular lens |
| KR102089715B1 (ko) * | 2016-06-22 | 2020-03-16 | 주식회사 엘지화학 | 공중합체, 이의 제조 방법, 및 이를 포함하는 친수성 코팅 조성물 |
| US10350056B2 (en) | 2016-12-23 | 2019-07-16 | Shifamed Holdings, Llc | Multi-piece accommodating intraocular lenses and methods for making and using same |
| JP6954679B2 (ja) | 2016-12-23 | 2021-10-27 | シファメド・ホールディングス・エルエルシー | マルチピース調節式眼内レンズ、及び同を作成し、使用するための方法 |
| JP7370052B2 (ja) | 2017-05-30 | 2023-10-27 | シファメド・ホールディングス・エルエルシー | 調節眼内レンズのための表面処理ならびに関連する方法およびデバイス |
| JP7082822B2 (ja) | 2017-06-07 | 2022-06-09 | シファメド・ホールディングス・エルエルシー | 調整可能な屈折力の眼内レンズ |
| US10836928B2 (en) * | 2017-12-15 | 2020-11-17 | Ppg Industries Ohio, Inc. | Polyoxazoline curing for packaging coating compositions |
| CN109820625A (zh) * | 2018-09-30 | 2019-05-31 | 四川大学 | 一种交联的人工生物瓣膜处理方法 |
| DE102018127812B4 (de) * | 2018-11-07 | 2020-06-18 | Fachhochschule Kiel | Kontaktlinse mit einer Oberflächenbeschichtung und Herstellungsverfahren |
| CN116157434A (zh) * | 2020-09-03 | 2023-05-23 | 大金工业株式会社 | 有机硅共聚物 |
| US20250321364A1 (en) * | 2024-04-15 | 2025-10-16 | Bausch + Lomb Ireland Limited | Surface modified ophthalmic devices |
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| US4153641A (en) | 1977-07-25 | 1979-05-08 | Bausch & Lomb Incorporated | Polysiloxane composition and contact lens |
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| KR100468803B1 (ko) | 1995-12-07 | 2005-04-19 | 바슈 앤드 롬 인코포레이티드 | 실리콘히드로겔의모듈러스를감소시키는데유용한단량체단위 |
| US5708094A (en) | 1996-12-17 | 1998-01-13 | Bausch & Lomb Incorporated | Polybutadiene-based compositions for contact lenses |
| CA2328897A1 (en) | 1998-05-05 | 1999-11-11 | Bausch & Lomb Incorporated | Plasma surface treatment of silicone hydrogel contact lenses |
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| JP2004339165A (ja) * | 2003-05-16 | 2004-12-02 | Asahi Kasei Corp | 医療用具用コート材およびこれを用いた白血球除去フィルター |
| WO2005068571A1 (ja) * | 2004-01-15 | 2005-07-28 | Menicon Co., Ltd. | 眼用レンズ表面のコーティング剤 |
| WO2007024500A1 (en) * | 2005-08-25 | 2007-03-01 | Medtronic Vascular, Inc. | Controlled radical polymerization-derived block copolymer compositions for medical device coatings |
| WO2007064594A2 (en) * | 2005-11-29 | 2007-06-07 | Bausch & Lomb Incorporated | New coatings on ophthalmic lenses |
| US7811555B2 (en) * | 2005-12-30 | 2010-10-12 | Cordis Corporation | Tri-branched biologically active copolymer |
| JP4832910B2 (ja) * | 2006-01-31 | 2011-12-07 | 株式会社メニコン | 眼用レンズ表面用コーティング剤およびそれにより得られる眼用レンズ |
-
2008
- 2008-12-16 JP JP2010540781A patent/JP2011508059A/ja active Pending
- 2008-12-16 EP EP08868283A patent/EP2235094A1/en not_active Withdrawn
- 2008-12-16 CN CN2008801271893A patent/CN101977972B/zh not_active Expired - Fee Related
- 2008-12-16 EP EP13151482.0A patent/EP2597113A1/en not_active Withdrawn
- 2008-12-16 WO PCT/US2008/086989 patent/WO2009085755A1/en not_active Ceased
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