JP2011504092A5 - - Google Patents
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- Publication number
- JP2011504092A5 JP2011504092A5 JP2010530629A JP2010530629A JP2011504092A5 JP 2011504092 A5 JP2011504092 A5 JP 2011504092A5 JP 2010530629 A JP2010530629 A JP 2010530629A JP 2010530629 A JP2010530629 A JP 2010530629A JP 2011504092 A5 JP2011504092 A5 JP 2011504092A5
- Authority
- JP
- Japan
- Prior art keywords
- vegf
- antibody
- composition
- fragment
- disorder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98243807P | 2007-10-25 | 2007-10-25 | |
| PCT/IL2008/001410 WO2009053987A1 (en) | 2007-10-25 | 2008-10-26 | Antibodies specific to pro-angiogenic isoforms of vascular endothelial growth factor (vegf) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011504092A JP2011504092A (ja) | 2011-02-03 |
| JP2011504092A5 true JP2011504092A5 (https=) | 2012-11-15 |
Family
ID=40385456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010530629A Pending JP2011504092A (ja) | 2007-10-25 | 2008-10-26 | 血管内皮増殖因子（ｖｅｇｆ）の血管新生誘発性アイソフォームに特異的な抗体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8592563B2 (https=) |
| EP (1) | EP2203480A1 (https=) |
| JP (1) | JP2011504092A (https=) |
| CN (1) | CN101970486A (https=) |
| AU (1) | AU2008315414A1 (https=) |
| CA (1) | CA2703154A1 (https=) |
| WO (1) | WO2009053987A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2066694T3 (en) * | 2006-09-29 | 2016-02-08 | Oncomed Pharm Inc | Compositions and Methods for Diagnosing and Treating Cancer |
| WO2010129304A2 (en) | 2009-04-27 | 2010-11-11 | Oncomed Pharmaceuticals, Inc. | Method for making heteromultimeric molecules |
| HUE029661T2 (en) | 2009-10-16 | 2017-03-28 | Oncomed Pharm Inc | A therapeutic combination and use of DLL4 antagonist antibodies and antihypertensive agents |
| WO2011084791A2 (en) * | 2009-12-21 | 2011-07-14 | Mayo Foundation For Medical Education And Research | Early marker of proteinuria in patients treated with an anti-vegf treatment |
| US8551479B2 (en) | 2010-09-10 | 2013-10-08 | Oncomed Pharmaceuticals, Inc. | Methods for treating melanoma |
| US8623666B2 (en) * | 2011-06-15 | 2014-01-07 | Hoffmann-La Roche Inc. | Method for detecting erythropoietin (EPO) receptor using anti-human EPO receptor antibodies |
| LT3485903T (lt) | 2011-09-23 | 2023-02-27 | Mereo Biopharma 5, Inc. | Vegf/ dll4 surišantys agentai ir jų panaudojimas |
| US9599620B2 (en) | 2012-10-31 | 2017-03-21 | Oncomed Pharmaceuticals, Inc. | Methods and monitoring of treatment with a DLL4 antagonist |
| WO2014117053A1 (en) * | 2013-01-27 | 2014-07-31 | The Cleveland Clinic Foundation | Anti-angiogenic vegf-ax isoform |
| ES2808153T3 (es) | 2014-10-31 | 2021-02-25 | Mereo Biopharma 5 Inc | Terapia de combinación para tratamiento de enfermedad |
| WO2016194708A1 (ja) * | 2015-05-29 | 2016-12-08 | 国立大学法人名古屋大学 | 尿中ＶＥＧＦ－Ａ１６５ｂを指標とした腎機能の検査方法及び検査装置、腎機能の検査装置として機能させるためのプログラム及び記録媒体 |
| US11339213B2 (en) | 2015-09-23 | 2022-05-24 | Mereo Biopharma 5, Inc. | Methods and compositions for treatment of cancer |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US6022541A (en) * | 1991-10-18 | 2000-02-08 | Beth Israel Deaconess Medical Center | Immunological preparation for concurrent specific binding to spatially exposed regions of vascular permeability factor bound in-vivo to a tumor associated blood vessel |
| US7667004B2 (en) * | 2001-04-17 | 2010-02-23 | Abmaxis, Inc. | Humanized antibodies against vascular endothelial growth factor |
| DE60235761D1 (de) * | 2001-08-01 | 2010-05-06 | Univ Bristol Clifton | Isoform des vegfs |
| US20050009110A1 (en) | 2003-07-08 | 2005-01-13 | Xiao-Jia Chang | Methods of producing antibodies for diagnostics and therapeutics |
| CA2604180A1 (en) * | 2005-04-29 | 2006-11-09 | (Osi) Eyetech, Inc. | Vegf variants |
| US20080031815A1 (en) * | 2006-07-27 | 2008-02-07 | Xiaoyuan Chen | Pet imaging of vascular endothelial growth factor receptor (VEGFR), compositions for VEGF cancer imaging, and methods of VEGF cancer imaging |
| GB0704678D0 (en) | 2007-03-09 | 2007-04-18 | Univ Bristol | Pro- and anti-angiogenic treatments |
-
2008
- 2008-10-26 EP EP08842953A patent/EP2203480A1/en not_active Withdrawn
- 2008-10-26 JP JP2010530629A patent/JP2011504092A/ja active Pending
- 2008-10-26 AU AU2008315414A patent/AU2008315414A1/en not_active Abandoned
- 2008-10-26 CA CA2703154A patent/CA2703154A1/en not_active Abandoned
- 2008-10-26 US US12/739,619 patent/US8592563B2/en not_active Expired - Fee Related
- 2008-10-26 CN CN2008801226493A patent/CN101970486A/zh active Pending
- 2008-10-26 WO PCT/IL2008/001410 patent/WO2009053987A1/en not_active Ceased
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