JP2011504092A5 - - Google Patents
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- Publication number
- JP2011504092A5 JP2011504092A5 JP2010530629A JP2010530629A JP2011504092A5 JP 2011504092 A5 JP2011504092 A5 JP 2011504092A5 JP 2010530629 A JP2010530629 A JP 2010530629A JP 2010530629 A JP2010530629 A JP 2010530629A JP 2011504092 A5 JP2011504092 A5 JP 2011504092A5
- Authority
- JP
- Japan
- Prior art keywords
- vegf
- antibody
- composition
- fragment
- disorder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98243807P | 2007-10-25 | 2007-10-25 | |
| PCT/IL2008/001410 WO2009053987A1 (en) | 2007-10-25 | 2008-10-26 | Antibodies specific to pro-angiogenic isoforms of vascular endothelial growth factor (vegf) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011504092A JP2011504092A (ja) | 2011-02-03 |
| JP2011504092A5 true JP2011504092A5 (https=) | 2012-11-15 |
Family
ID=40385456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010530629A Pending JP2011504092A (ja) | 2007-10-25 | 2008-10-26 | 血管内皮増殖因子（ｖｅｇｆ）の血管新生誘発性アイソフォームに特異的な抗体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8592563B2 (https=) |
| EP (1) | EP2203480A1 (https=) |
| JP (1) | JP2011504092A (https=) |
| CN (1) | CN101970486A (https=) |
| AU (1) | AU2008315414A1 (https=) |
| CA (1) | CA2703154A1 (https=) |
| WO (1) | WO2009053987A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA018260B1 (ru) | 2006-09-29 | 2013-06-28 | Онкомед Фармасьютикалз, Инк. | Антитела к дельта-подобному лиганду 4 человека и их применение |
| JP2012525149A (ja) | 2009-04-27 | 2012-10-22 | オンコメッド ファーマシューティカルズ インコーポレイテッド | ヘテロ多量体分子を作製するための方法 |
| ES2700450T3 (es) | 2009-10-16 | 2019-02-15 | Oncomed Pharm Inc | Combinación terapéutica y uso de anticuerpos antagonistas de DLL4 y agentes antihipertensores |
| US20130034861A1 (en) * | 2009-12-21 | 2013-02-07 | Mayo Foundation For Medical Education And Research | Early marker of proteinuria in patients treated with an anti-vegf treatment |
| US8551479B2 (en) | 2010-09-10 | 2013-10-08 | Oncomed Pharmaceuticals, Inc. | Methods for treating melanoma |
| CA2837914A1 (en) * | 2011-06-15 | 2012-12-20 | F. Hoffmann-La Roche Ag | Anti-human epo receptor antibodies and methods of use |
| LT3485903T (lt) | 2011-09-23 | 2023-02-27 | Mereo Biopharma 5, Inc. | Vegf/ dll4 surišantys agentai ir jų panaudojimas |
| US9599620B2 (en) | 2012-10-31 | 2017-03-21 | Oncomed Pharmaceuticals, Inc. | Methods and monitoring of treatment with a DLL4 antagonist |
| WO2014117053A1 (en) * | 2013-01-27 | 2014-07-31 | The Cleveland Clinic Foundation | Anti-angiogenic vegf-ax isoform |
| WO2016070051A2 (en) | 2014-10-31 | 2016-05-06 | Oncomed Pharmaceuticals, Inc. | Combination therapy for treatment of disease |
| JP6675687B2 (ja) * | 2015-05-29 | 2020-04-01 | 国立大学法人名古屋大学 | 尿中ＶＥＧＦ−Ａ１６５ｂを指標とした腎機能の検査方法及び検査装置、腎機能の検査装置として機能させるためのプログラム及び記録媒体 |
| EP3353204B1 (en) | 2015-09-23 | 2023-10-18 | Mereo BioPharma 5, Inc. | Bi-specific anti-vegf/dll4 antibody for use in treating platinum-resistant ovarian cancer |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US6022541A (en) | 1991-10-18 | 2000-02-08 | Beth Israel Deaconess Medical Center | Immunological preparation for concurrent specific binding to spatially exposed regions of vascular permeability factor bound in-vivo to a tumor associated blood vessel |
| US7667004B2 (en) | 2001-04-17 | 2010-02-23 | Abmaxis, Inc. | Humanized antibodies against vascular endothelial growth factor |
| US7820178B2 (en) * | 2001-08-01 | 2010-10-26 | University of Brisol | VEGF isoforms and their use as anti-angiogenic, anti-vasodilatory, anti-permeability and anti-proliferative agents |
| US20050009110A1 (en) | 2003-07-08 | 2005-01-13 | Xiao-Jia Chang | Methods of producing antibodies for diagnostics and therapeutics |
| AU2006242449A1 (en) * | 2005-04-29 | 2006-11-09 | (Osi) Eyetech, Inc. | VEGF variants |
| US20080031815A1 (en) * | 2006-07-27 | 2008-02-07 | Xiaoyuan Chen | Pet imaging of vascular endothelial growth factor receptor (VEGFR), compositions for VEGF cancer imaging, and methods of VEGF cancer imaging |
| GB0704678D0 (en) | 2007-03-09 | 2007-04-18 | Univ Bristol | Pro- and anti-angiogenic treatments |
-
2008
- 2008-10-26 CN CN2008801226493A patent/CN101970486A/zh active Pending
- 2008-10-26 US US12/739,619 patent/US8592563B2/en not_active Expired - Fee Related
- 2008-10-26 JP JP2010530629A patent/JP2011504092A/ja active Pending
- 2008-10-26 CA CA2703154A patent/CA2703154A1/en not_active Abandoned
- 2008-10-26 WO PCT/IL2008/001410 patent/WO2009053987A1/en not_active Ceased
- 2008-10-26 EP EP08842953A patent/EP2203480A1/en not_active Withdrawn
- 2008-10-26 AU AU2008315414A patent/AU2008315414A1/en not_active Abandoned
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