JP2011224009A5 - - Google Patents

Info

Publication number

JP2011224009A5

JP2011224009A5 JP2011118610A JP2011118610A JP2011224009A5 JP 2011224009 A5 JP2011224009 A5 JP 2011224009A5 JP 2011118610 A JP2011118610 A JP 2011118610A JP 2011118610 A JP2011118610 A JP 2011118610A JP 2011224009 A5 JP2011224009 A5 JP 2011224009A5

Authority

JP

Japan

Prior art keywords

medium

stem cell

avian

serum

vaccinia virus

Prior art date

2011-05-27

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
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• 241000271566 Aves Species 0.000 claims 24
• 210000000130 stem cell Anatomy 0.000 claims 19
• 238000000034 method Methods 0.000 claims 18
• 210000001161 mammalian embryo Anatomy 0.000 claims 15
• 239000003102 growth factor Substances 0.000 claims 12
• 108090000695 Cytokines Proteins 0.000 claims 11
• 102000004127 Cytokines Human genes 0.000 claims 11
• 239000002609 medium Substances 0.000 claims 10
• 210000001671 embryonic stem cell Anatomy 0.000 claims 9
• 241001183012 Modified Vaccinia Ankara virus Species 0.000 claims 8
• 241000700618 Vaccinia virus Species 0.000 claims 8
• 210000002966 serum Anatomy 0.000 claims 8
• 241000700605 Viruses Species 0.000 claims 7
• 230000001464 adherent effect Effects 0.000 claims 7
• 239000007640 basal medium Substances 0.000 claims 7
• 241000700629 Orthopoxvirus Species 0.000 claims 6
• 210000004027 cell Anatomy 0.000 claims 6
• 238000012258 culturing Methods 0.000 claims 4
• 230000000694 effects Effects 0.000 claims 4
• 239000000725 suspension Substances 0.000 claims 4
• LAQPKDLYOBZWBT-NYLDSJSYSA-N (2s,4s,5r,6r)-5-acetamido-2-{[(2s,3r,4s,5s,6r)-2-{[(2r,3r,4r,5r)-5-acetamido-1,2-dihydroxy-6-oxo-4-{[(2s,3s,4r,5s,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}hexan-3-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-4-hydroxy-6-[(1r,2r)-1,2,3-trihydrox Chemical compound O[C@H]1[C@H](O)[C@H](O)[C@H](C)O[C@H]1O[C@H]([C@@H](NC(C)=O)C=O)[C@@H]([C@H](O)CO)O[C@H]1[C@H](O)[C@@H](O[C@]2(O[C@H]([C@H](NC(C)=O)[C@@H](O)C2)[C@H](O)[C@H](O)CO)C(O)=O)[C@@H](O)[C@@H](CO)O1 LAQPKDLYOBZWBT-NYLDSJSYSA-N 0.000 claims 2
• 102000002260 Alkaline Phosphatase Human genes 0.000 claims 2
• 108020004774 Alkaline Phosphatase Proteins 0.000 claims 2
• 241000272525 Anas platyrhynchos Species 0.000 claims 2
• 239000006144 Dulbecco’s modified Eagle's medium Substances 0.000 claims 2
• 241000287828 Gallus gallus Species 0.000 claims 2
• HPFXACZRFJDURI-KTKRTIGZSA-N N-oleoylglycine Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)NCC(O)=O HPFXACZRFJDURI-KTKRTIGZSA-N 0.000 claims 2
• -1 SSEA-3 Chemical compound 0.000 claims 2
• 108010017842 Telomerase Proteins 0.000 claims 2
• 239000000654 additive Substances 0.000 claims 2
• 238000004519 manufacturing process Methods 0.000 claims 2
• 239000002245 particle Substances 0.000 claims 2
• 239000012679 serum free medium Substances 0.000 claims 2
• DAEPDZWVDSPTHF-UHFFFAOYSA-M sodium pyruvate Chemical compound [Na+].CC(=O)C([O-])=O DAEPDZWVDSPTHF-UHFFFAOYSA-M 0.000 claims 2
• 108010005939 Ciliary Neurotrophic Factor Proteins 0.000 claims 1
• 102100031614 Ciliary neurotrophic factor Human genes 0.000 claims 1
• 102100024785 Fibroblast growth factor 2 Human genes 0.000 claims 1
• 108090000379 Fibroblast growth factor 2 Proteins 0.000 claims 1
• 108090000723 Insulin-Like Growth Factor I Proteins 0.000 claims 1
• 102000004218 Insulin-Like Growth Factor I Human genes 0.000 claims 1
• 102000003815 Interleukin-11 Human genes 0.000 claims 1
• 108090000177 Interleukin-11 Proteins 0.000 claims 1
• 108090001005 Interleukin-6 Proteins 0.000 claims 1
• 102000004889 Interleukin-6 Human genes 0.000 claims 1
• 102100037792 Interleukin-6 receptor subunit alpha Human genes 0.000 claims 1
• 239000007760 Iscove's Modified Dulbecco's Medium Substances 0.000 claims 1
• 102100020880 Kit ligand Human genes 0.000 claims 1
• 101710177504 Kit ligand Proteins 0.000 claims 1
• 102100032352 Leukemia inhibitory factor Human genes 0.000 claims 1
• 108090000581 Leukemia inhibitory factor Proteins 0.000 claims 1
• 239000012980 RPMI-1640 medium Substances 0.000 claims 1
• 230000000996 additive effect Effects 0.000 claims 1
• 230000006037 cell lysis Effects 0.000 claims 1
• 239000003797 essential amino acid Substances 0.000 claims 1
• 235000020776 essential amino acid Nutrition 0.000 claims 1
• 208000015181 infectious disease Diseases 0.000 claims 1
• 238000011081 inoculation Methods 0.000 claims 1
• 108040006858 interleukin-6 receptor activity proteins Proteins 0.000 claims 1
• 230000003362 replicative effect Effects 0.000 claims 1
• 229940054269 sodium pyruvate Drugs 0.000 claims 1
• 230000001502 supplementing effect Effects 0.000 claims 1
• 229960005486 vaccine Drugs 0.000 claims 1
• 230000003612 virological effect Effects 0.000 claims 1
• 239000011782 vitamin Substances 0.000 claims 1
• 229940088594 vitamin Drugs 0.000 claims 1
• 229930003231 vitamin Natural products 0.000 claims 1
• 235000013343 vitamin Nutrition 0.000 claims 1
• 150000003722 vitamin derivatives Chemical class 0.000 claims 1