JP2011162566A5 - - Google Patents
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- Publication number
- JP2011162566A5 JP2011162566A5 JP2011119770A JP2011119770A JP2011162566A5 JP 2011162566 A5 JP2011162566 A5 JP 2011162566A5 JP 2011119770 A JP2011119770 A JP 2011119770A JP 2011119770 A JP2011119770 A JP 2011119770A JP 2011162566 A5 JP2011162566 A5 JP 2011162566A5
- Authority
- JP
- Japan
- Prior art keywords
- carbamate
- substituted
- methyl
- unsubstituted
- aliphatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57362304P | 2004-05-21 | 2004-05-21 | |
| US60/573,623 | 2004-05-21 | ||
| US66094705P | 2005-03-11 | 2005-03-11 | |
| US60/660,947 | 2005-03-11 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007527494A Division JP5242161B2 (ja) | 2004-05-21 | 2005-05-20 | テトラサイクリンおよびそれらの類似物の合成 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013164980A Division JP2013227346A (ja) | 2004-05-21 | 2013-08-08 | テトラサイクリンおよびそれらの類似物の合成 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011162566A JP2011162566A (ja) | 2011-08-25 |
| JP2011162566A5 true JP2011162566A5 (cg-RX-API-DMAC7.html) | 2016-05-19 |
| JP5971900B2 JP5971900B2 (ja) | 2016-08-17 |
Family
ID=35428840
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007527494A Expired - Lifetime JP5242161B2 (ja) | 2004-05-21 | 2005-05-20 | テトラサイクリンおよびそれらの類似物の合成 |
| JP2011119770A Expired - Lifetime JP5971900B2 (ja) | 2004-05-21 | 2011-05-27 | テトラサイクリンおよびそれらの類似物の合成 |
| JP2013164980A Withdrawn JP2013227346A (ja) | 2004-05-21 | 2013-08-08 | テトラサイクリンおよびそれらの類似物の合成 |
| JP2015168496A Expired - Lifetime JP6185966B2 (ja) | 2004-05-21 | 2015-08-28 | テトラサイクリンおよびそれらの類似物の合成 |
| JP2016243003A Pending JP2017052797A (ja) | 2004-05-21 | 2016-12-15 | テトラサイクリンおよびそれらの類似物の合成 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007527494A Expired - Lifetime JP5242161B2 (ja) | 2004-05-21 | 2005-05-20 | テトラサイクリンおよびそれらの類似物の合成 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013164980A Withdrawn JP2013227346A (ja) | 2004-05-21 | 2013-08-08 | テトラサイクリンおよびそれらの類似物の合成 |
| JP2015168496A Expired - Lifetime JP6185966B2 (ja) | 2004-05-21 | 2015-08-28 | テトラサイクリンおよびそれらの類似物の合成 |
| JP2016243003A Pending JP2017052797A (ja) | 2004-05-21 | 2016-12-15 | テトラサイクリンおよびそれらの類似物の合成 |
Country Status (19)
| Country | Link |
|---|---|
| US (6) | US7807842B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP1753713B1 (cg-RX-API-DMAC7.html) |
| JP (5) | JP5242161B2 (cg-RX-API-DMAC7.html) |
| KR (2) | KR101171408B1 (cg-RX-API-DMAC7.html) |
| CN (3) | CN101027279B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2005244988C1 (cg-RX-API-DMAC7.html) |
| BR (2) | BRPI0510113B1 (cg-RX-API-DMAC7.html) |
| CA (3) | CA2566464C (cg-RX-API-DMAC7.html) |
| CY (1) | CY1118519T1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1753713T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2607453T3 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE030212T2 (cg-RX-API-DMAC7.html) |
| IL (5) | IL179467A (cg-RX-API-DMAC7.html) |
| LT (1) | LT1753713T (cg-RX-API-DMAC7.html) |
| PL (1) | PL1753713T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT1753713T (cg-RX-API-DMAC7.html) |
| SG (1) | SG10201810312UA (cg-RX-API-DMAC7.html) |
| SI (1) | SI1753713T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2005112945A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020132798A1 (en) | 2000-06-16 | 2002-09-19 | Nelson Mark L. | 7-phenyl-substituted tetracycline compounds |
| US7094806B2 (en) | 2000-07-07 | 2006-08-22 | Trustees Of Tufts College | 7, 8 and 9-substituted tetracycline compounds |
| US7553828B2 (en) | 2001-03-13 | 2009-06-30 | Paratek Pharmaceuticals, Inc. | 9-aminomethyl substituted minocycline compounds |
| WO2002072506A2 (en) * | 2001-03-13 | 2002-09-19 | Paratek Pharmaceuticals, Inc. | 7-pyrollyl tetracycline compounds and methods of use thereof |
| CA2440757A1 (en) | 2001-03-14 | 2002-09-19 | Michael Draper | Substituted tetracycline compounds as synergistic antifungal agents |
| WO2003055441A2 (en) * | 2001-08-02 | 2003-07-10 | Paratek Pharmaceuticals, Inc. | Medicaments |
| CN102531948A (zh) * | 2002-03-08 | 2012-07-04 | 帕拉特克药品公司 | 氨基-甲基取代的四环素类化合物 |
| EA012136B1 (ru) * | 2002-07-12 | 2009-08-28 | Пэрэтек Фамэсьютикэлс, Инк. | Замещенные соединения тетрациклина, фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта |
| EP2319828A3 (en) | 2003-07-09 | 2011-07-06 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds |
| CA2566464C (en) | 2004-05-21 | 2012-04-03 | Andrew G. Myers | Synthesis of tetracyclines and analogues thereof |
| CA2585418A1 (en) * | 2004-10-25 | 2006-05-04 | Paratek Pharmaceuticals, Inc. | 4-aminotetracyclines and methods of use thereof |
| EP2284153A3 (en) | 2004-10-25 | 2012-03-14 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds |
| AU2006210406C1 (en) | 2005-02-04 | 2013-03-07 | Paratek Pharmaceuticals, Inc. | 11a, 12-derivatives of tetracycline compounds |
| US20070093455A1 (en) * | 2005-07-21 | 2007-04-26 | Paul Abato | 10-substituted tetracyclines and methods of use thereof |
| US8486921B2 (en) | 2006-04-07 | 2013-07-16 | President And Fellows Of Harvard College | Synthesis of tetracyclines and analogues thereof |
| WO2008045507A2 (en) * | 2006-10-11 | 2008-04-17 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds for treatment of bacillus anthracis infections |
| WO2008127361A2 (en) | 2006-10-11 | 2008-10-23 | President And Fellows Of Harvard College | Synthesis of enone intermediate |
| SI2109602T1 (sl) * | 2006-12-21 | 2014-06-30 | Paratek Pharmaceuticals, Inc. | Derivati tetraciklina za zdravljenje bakterijskih, virusnih in parazitskih infekcij |
| US20080305186A1 (en) * | 2007-06-11 | 2008-12-11 | Board Of Regents, The University Of Texas System | Method and Composition for the Treatment of Cardiac Hypertrophy |
| DE102008028334B4 (de) * | 2008-06-13 | 2014-02-27 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Probenkammer-Adapter für die Kryokonservierung biologischer Proben |
| US8338477B2 (en) * | 2008-07-11 | 2012-12-25 | Neumedics | Tetracycline derivatives with reduced antibiotic activity and neuroprotective benefits |
| EP3000805B1 (en) | 2008-08-08 | 2017-10-18 | Tetraphase Pharmaceuticals, Inc. | C7-fluoro substituted tetracycline compounds |
| EP2424834B1 (en) | 2009-04-30 | 2018-07-11 | President and Fellows of Harvard College | Synthesis of tetracyclines and intermediates thereof |
| CA2761241C (en) | 2009-05-08 | 2018-02-27 | Tetraphase Pharmaceuticals, Inc. | Tetracycline compounds |
| EP2427190B1 (en) | 2009-05-08 | 2013-09-18 | Tetraphase Pharmaceuticals, Inc. | 8-aza tetracycline compounds |
| US20120115819A1 (en) * | 2009-05-13 | 2012-05-10 | Clark Roger B | Pentacycline Compounds |
| NO2470500T3 (cg-RX-API-DMAC7.html) | 2009-08-28 | 2018-03-03 | ||
| SG184372A1 (en) * | 2010-03-31 | 2012-11-29 | Tetraphase Pharmaceuticals Inc | Polycyclic tetracycline compounds |
| WO2012047907A1 (en) | 2010-10-04 | 2012-04-12 | President And Fellows Of Harvard College | Synthesis of c5-substituted tetracyclines, uses thereof, and intermediates thereto |
| CN102675145B (zh) * | 2012-04-27 | 2013-10-16 | 山东恩康药业有限公司 | 一种愈创木酚磺酸多西环素的制备方法 |
| CN103387511B (zh) * | 2012-05-08 | 2016-12-28 | 成都睿智化学研究有限公司 | 一种山环素的制备方法 |
| TR201902057T4 (tr) | 2012-08-31 | 2019-03-21 | Tetraphase Pharmaceuticals Inc | Tetrasiklin bileşikleri. |
| CN103044281A (zh) * | 2013-01-02 | 2013-04-17 | 湖南赛隆药业有限公司 | 高纯度替加环素的制法 |
| WO2016062279A1 (zh) * | 2014-10-24 | 2016-04-28 | 朗齐生物医学股份有限公司 | 苹果酸丙氯陪拉辛锭用于制备治疗癌症药物的用途 |
| WO2016141480A1 (en) * | 2015-03-09 | 2016-09-15 | Mount Sinai Hospital | Tools and methods for using cell division loci to control proliferation of cells |
| BR112017020358A2 (pt) | 2015-03-23 | 2018-07-17 | Biopharmx Inc | composição farmacêutica de tetraciclina para uso dermatológico |
| CN107188875B (zh) * | 2016-03-15 | 2020-11-10 | 联化科技股份有限公司 | 一种取代苯酞类化合物的制备方法及其中间体 |
| HRP20240605T1 (hr) | 2016-10-19 | 2024-07-19 | Tetraphase Pharmaceuticals, Inc. | Kristalni oblici eravaciklina |
| CA3234239A1 (en) | 2018-06-13 | 2019-12-19 | Texas Tech University System | Modified tetracycline for treatment of alcohol use disorder, pain and other disorders involving potential inflammatory processes |
| GB201914847D0 (en) * | 2019-10-14 | 2019-11-27 | Helperby Therapeutics Ltd | Combination |
| CN112979666A (zh) * | 2019-12-18 | 2021-06-18 | 中国科学院生态环境研究中心 | 土霉素衍生物、制备方法及其检测方法 |
| CN115340446B (zh) * | 2021-05-12 | 2024-04-19 | 复旦大学 | 一种手性苯并环丁烯醇、其合成方法及用途 |
| CN113388556B (zh) * | 2021-08-02 | 2022-12-02 | 金河生物科技股份有限公司 | 利用金色链霉菌生产金霉素的方法 |
| CN113929593B (zh) * | 2021-09-02 | 2024-05-31 | 河北圣雪大成唐山制药有限责任公司 | 一种土霉素-2,5-二羟基苯甲酸共晶及其制备方法 |
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