JP2011153154A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011153154A5 JP2011153154A5 JP2011104235A JP2011104235A JP2011153154A5 JP 2011153154 A5 JP2011153154 A5 JP 2011153154A5 JP 2011104235 A JP2011104235 A JP 2011104235A JP 2011104235 A JP2011104235 A JP 2011104235A JP 2011153154 A5 JP2011153154 A5 JP 2011153154A5
- Authority
- JP
- Japan
- Prior art keywords
- drug
- formulation
- coating
- hours
- central tablet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 21
- 238000009472 formulation Methods 0.000 claims 20
- 229940079593 drug Drugs 0.000 claims 19
- 239000003814 drug Substances 0.000 claims 19
- 239000011248 coating agent Substances 0.000 claims 11
- 238000000576 coating method Methods 0.000 claims 11
- 238000013270 controlled release Methods 0.000 claims 5
- 230000036470 plasma concentration Effects 0.000 claims 5
- 238000002360 preparation method Methods 0.000 claims 5
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims 4
- TVYLLZQTGLZFBW-ZBFHGGJFSA-N (R,R)-tramadol Chemical compound COC1=CC=CC([C@]2(O)[C@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-ZBFHGGJFSA-N 0.000 claims 3
- 238000005259 measurement Methods 0.000 claims 3
- 229960004380 tramadol Drugs 0.000 claims 3
- TVYLLZQTGLZFBW-GOEBONIOSA-N tramadol Natural products COC1=CC=CC([C@@]2(O)[C@@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-GOEBONIOSA-N 0.000 claims 3
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims 2
- 125000000524 functional group Chemical group 0.000 claims 2
- 229920002689 polyvinyl acetate Polymers 0.000 claims 2
- 239000011118 polyvinyl acetate Substances 0.000 claims 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 229920001685 Amylomaize Polymers 0.000 claims 1
- 230000008030 elimination Effects 0.000 claims 1
- 238000003379 elimination reaction Methods 0.000 claims 1
- 210000004211 gastric acid Anatomy 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 239000008203 oral pharmaceutical composition Substances 0.000 claims 1
- 239000006069 physical mixture Substances 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 229920001285 xanthan gum Polymers 0.000 claims 1
- 235000010493 xanthan gum Nutrition 0.000 claims 1
- 239000000230 xanthan gum Substances 0.000 claims 1
- 229940082509 xanthan gum Drugs 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28102602A | 2002-10-25 | 2002-10-25 | |
| US10/281,026 | 2002-10-25 | ||
| US51000003P | 2003-10-10 | 2003-10-10 | |
| US60/510,000 | 2003-10-10 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004545654A Division JP2006507276A (ja) | 2002-10-25 | 2003-10-27 | 放出制御組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011153154A JP2011153154A (ja) | 2011-08-11 |
| JP2011153154A5 true JP2011153154A5 (enExample) | 2012-01-12 |
| JP4897930B2 JP4897930B2 (ja) | 2012-03-14 |
Family
ID=44539364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011104235A Expired - Lifetime JP4897930B2 (ja) | 2002-10-25 | 2011-05-09 | 放出制御組成物 |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP4897930B2 (enExample) |
| IL (1) | IL168113A (enExample) |
| MY (1) | MY142195A (enExample) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2173818A1 (fr) * | 1996-04-10 | 1997-10-11 | Francois Chouinard | Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose |
| DE10015479A1 (de) * | 2000-03-29 | 2001-10-11 | Basf Ag | Feste orale Darreichungsformen mit retardierter Wirkstofffreisetzung und hoher mechanischer Stabilität |
| US6607748B1 (en) * | 2000-06-29 | 2003-08-19 | Vincent Lenaerts | Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture |
-
2003
- 2003-10-25 MY MYPI20034063 patent/MY142195A/en unknown
-
2005
- 2005-04-19 IL IL168113A patent/IL168113A/en active IP Right Grant
-
2011
- 2011-05-09 JP JP2011104235A patent/JP4897930B2/ja not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5775464B2 (ja) | 非晶質ｃｄｄｏ−ｍｅを含有する遅延放出性経口投薬組成物 | |
| ES2683864T3 (es) | Composiciones de corticosteroides administradas oralmente | |
| JP2010090168A5 (enExample) | ||
| JP2005526043A5 (enExample) | ||
| PH12015502134B1 (en) | Mosapride sustained-release formulation providing pharmacological and clinical effects with once-daily administration | |
| JP2013501718A5 (enExample) | ||
| JP2008520736A5 (enExample) | ||
| WO2011107855A3 (en) | Sustained release oral liquid suspension dosage form | |
| CN103889455B (zh) | 稳定化乙哌立松医药组成物及含有上述组成物的缓释制剂 | |
| CN106163566A (zh) | 稳定性提高的含普瑞巴林的药物组合物及其制备方法 | |
| EP2540318B1 (en) | Sustained-release solid preparation for oral use | |
| EP2961383A1 (en) | Suspension for oral administration comprising amorphous tolvaptan | |
| JP2020518611A (ja) | 水溶解度及びバイオアベイラビリティが改善された組成物 | |
| US9668975B2 (en) | Method of preparing drug agglomerate | |
| KR20180127951A (ko) | 바레니클린 서방성 제제 및 이의 제조 방법 | |
| ES2663357T3 (es) | Formulaciones de mazindol | |
| CN105407925A (zh) | 用于泡腾剂型的制造工艺 | |
| ES2261006B1 (es) | Pellet multicapa de liberacion controlada de metilfenidato. | |
| ES2424865T3 (es) | Formulación farmacéutica oral de liberación rápida para esomeprazol | |
| CN105769773B (zh) | 洛索洛芬钠缓释微丸 | |
| TW202341997A (zh) | 用於治療腸胃疾病或病狀之神經活性類固醇 | |
| JP2008517988A5 (enExample) | ||
| JP2012140335A (ja) | 不快味マスキング粒子及びこれを含有する経口製剤 | |
| JP2011046666A (ja) | 医薬組成物 | |
| CN107072954B (zh) | 用于口服给药的包含洛贝格列酮的药物组合物 |