JP2011057670A5 - - Google Patents
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- Publication number
- JP2011057670A5 JP2011057670A5 JP2010189054A JP2010189054A JP2011057670A5 JP 2011057670 A5 JP2011057670 A5 JP 2011057670A5 JP 2010189054 A JP2010189054 A JP 2010189054A JP 2010189054 A JP2010189054 A JP 2010189054A JP 2011057670 A5 JP2011057670 A5 JP 2011057670A5
- Authority
- JP
- Japan
- Prior art keywords
- nervous system
- central nervous
- reducing
- glp
- leukocyte infiltration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23765409P | 2009-08-27 | 2009-08-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011057670A JP2011057670A (ja) | 2011-03-24 |
| JP2011057670A5 true JP2011057670A5 (OSRAM) | 2013-10-10 |
Family
ID=43384669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010189054A Withdrawn JP2011057670A (ja) | 2009-08-27 | 2010-08-26 | 自己免疫障害を処置するためのグルカゴン様ペプチド−１受容体（ｇｌｐ−１ｒ）アゴニスト |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20120148586A1 (OSRAM) |
| EP (1) | EP2470198A2 (OSRAM) |
| JP (1) | JP2011057670A (OSRAM) |
| KR (1) | KR20120050460A (OSRAM) |
| CN (1) | CN102596229A (OSRAM) |
| AU (1) | AU2010288191A1 (OSRAM) |
| BR (1) | BR112012004043A2 (OSRAM) |
| CA (1) | CA2769835A1 (OSRAM) |
| IL (1) | IL217967A0 (OSRAM) |
| IN (1) | IN2012DN00961A (OSRAM) |
| MX (1) | MX2012002463A (OSRAM) |
| RU (1) | RU2012106200A (OSRAM) |
| WO (1) | WO2011024110A2 (OSRAM) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012356219B2 (en) * | 2011-12-22 | 2016-03-31 | Covx Technologies Ireland Limited | Anti-diabetic compounds |
| SG11201407860PA (en) | 2012-06-14 | 2014-12-30 | Sanofi Sa | Exendin-4 peptide analogues |
| UA116217C2 (uk) * | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| US20140107028A1 (en) * | 2012-10-15 | 2014-04-17 | The University Of Chicago | Methods and compositions for predicting response to glp-1 analogs |
| JP2016506401A (ja) | 2012-12-21 | 2016-03-03 | サノフイ | 二重ｇｌｐ１／ｇｉｐまたは三方ｇｌｐ１／ｇｉｐ／グルカゴンアゴニストとしてのエキセンジン−４誘導体 |
| US20160082137A1 (en) * | 2013-07-25 | 2016-03-24 | Sloan-Kettering Institute For Cancer Research | Clinical Multimodality-Tools for Pre-And Intraoperative Insulinoma Diagnostics |
| WO2015086733A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/glucagon receptor agonists |
| WO2015086731A1 (en) * | 2013-12-13 | 2015-06-18 | Sanofi | Exendin-4 peptide analogues as dual glp-1/glucagon receptor agonists |
| TW201609799A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重ｇｌｐ－１／ｇｉｐ受體促效劑 |
| TW201609796A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 非醯化之艾塞那肽－４（ｅｘｅｎｄｉｎ－４）胜肽類似物 |
| EP3080150B1 (en) | 2013-12-13 | 2018-08-01 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
| AR098614A1 (es) * | 2013-12-18 | 2016-06-01 | Lilly Co Eli | Compuesto para el tratamiento de hipoglicemia severa |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑 |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑 |
| TW201625668A (zh) * | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| TW201706291A (zh) | 2015-07-10 | 2017-02-16 | 賽諾菲公司 | 作為選擇性肽雙重ｇｌｐ－１／升糖素受體促效劑之新毒蜥外泌肽（ｅｘｅｎｄｉｎ－４）衍生物 |
| US12098202B2 (en) * | 2016-10-10 | 2024-09-24 | The National Institute for Biotechnology in the Negev Ltd. | Non-cytotoxic modified cells and use thereof |
| WO2018078112A1 (en) * | 2016-10-27 | 2018-05-03 | Aarhus Universitet | Glp-1 agonist (eg liraglutide) for use in the treatment of multiple sclerosis |
| AR110300A1 (es) * | 2016-12-02 | 2019-03-13 | Sanofi Sa | Compuestos como agonistas peptídicos trigonales de los receptores de glp1 / glucagón / gip |
| WO2018226590A1 (en) * | 2017-06-05 | 2018-12-13 | The Trustees Of Columbia University In The City Of New York | Peptides as biomarkers in the diagnosis, confirmation and treatment of a neurological disorder and immunoprofiling in neurodegenerative disease |
| JP7239566B2 (ja) | 2017-09-22 | 2023-03-14 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | グルカゴン様ペプチド１受容体アゴニストおよびそれらの使用 |
| AU2019237507B2 (en) | 2018-03-23 | 2025-04-03 | Carmot Therapeutics, Inc. | Modulators of G-protein coupled receptors |
| PE20231066A1 (es) | 2020-02-07 | 2023-07-17 | Gasherbrum Bio Inc | Agonistas heterociclicos de glp-1 |
| EP4143183B1 (en) | 2020-04-29 | 2025-10-22 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| MX2023002974A (es) * | 2020-09-14 | 2023-05-25 | Regeneron Pharma | Conjugados de anticuerpo-farmaco que comprenden peptidomimeticos glp1 y usos de los mismos. |
| EP4334304A1 (en) | 2021-05-03 | 2024-03-13 | Carmot Therapeutics, Inc. | Benzimidazoyl glp-1 receptor agonists, pharmaceutical compositions comprising the same, and methods for their use |
| IL308392A (en) | 2021-05-13 | 2024-01-01 | Carmot Therapeutics Inc | G protein-coupled receptor modulators |
| JP2025509281A (ja) | 2022-03-09 | 2025-04-11 | ガシャーブラム・バイオ・インコーポレイテッド | ヘテロ環式ｇｌｐ－１アゴニスト |
| AU2023231305A1 (en) * | 2022-03-11 | 2024-09-12 | Regeneron Pharmaceuticals, Inc. | Anti-GLP1r antibody-tethered drug conjugates comprising GLP1 peptidomimetics and uses thereof |
| EP4496797A1 (en) | 2022-03-21 | 2025-01-29 | Gasherbrum Bio, Inc. | 5,8-dihydro-1,7-naphthyridine derivatives as glp-1 agonists for the treatment of diabetes |
| EP4508047A1 (en) | 2022-04-14 | 2025-02-19 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| WO2024026338A1 (en) | 2022-07-27 | 2024-02-01 | Carmot Therapeutics, Inc. | N-heterocylic gpcr receptor agonists, pharmaceutical compositions comprising the same, and methods for their use |
| KR20250075642A (ko) | 2022-09-21 | 2025-05-28 | 리제너론 파아마슈티컬스, 인크. | 비만, 당뇨병 및 간 기능 장애를 치료하는 방법 |
| KR20250157491A (ko) | 2022-12-15 | 2025-11-04 | 가셔브룸 바이오, 인크. | Glp-1 효능제 활성을 갖는 화합물의 염 및 고체 형태 |
| EP4638440A1 (en) | 2022-12-22 | 2025-10-29 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| CN120693338A (zh) | 2022-12-22 | 2025-09-23 | 加舒布鲁姆生物公司 | 杂环的glp-1激动剂 |
| IL322686A (en) | 2023-02-16 | 2025-10-01 | Gasherbrum Bio Inc | Heterocyclic glp-1 agonists |
| CN121773120A (zh) | 2023-06-30 | 2026-03-31 | 加舒布鲁姆生物公司 | 杂环glp-1激动剂 |
| EP4743174A1 (en) | 2023-07-13 | 2026-05-20 | Aconcagua Bio Inc | CALCITONIN AND/OR AMYLIN RECEPTOR ACTIVITY MODULATORS |
| AR133241A1 (es) | 2023-07-13 | 2025-09-10 | Aconcagua Bio Inc | Compuestos, composiciones y métodos |
| WO2025045208A1 (en) | 2023-08-31 | 2025-03-06 | Gasherbrum Bio, Inc. | Heteroaryl-heterocycloalkyl-based glp-1 agonists |
| WO2025137307A1 (en) | 2023-12-20 | 2025-06-26 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| WO2025171341A2 (en) | 2024-02-08 | 2025-08-14 | Aconcagua Bio, Inc. | Compounds and compositions for treating conditions associated with calcitonin receptor and/or amylin receptor activity |
| WO2025171340A1 (en) | 2024-02-08 | 2025-08-14 | Aconcagua Bio, Inc. | The treatment of calcitonin- and/or amylin-receptor associated conditions |
| WO2026041075A1 (en) | 2024-08-21 | 2026-02-26 | Gasherbrum Bio, Inc. | Gpl-1 agonists |
| WO2026096926A1 (en) | 2024-11-01 | 2026-05-07 | Aconcagua Bio, Inc. | Compounds, compositions, and methods |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4754065A (en) | 1984-12-18 | 1988-06-28 | Cetus Corporation | Precursor to nucleic acid probe |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| DE69126871T2 (de) | 1990-04-06 | 1998-03-12 | Jolla Cancer Res Found | Verfahren und verbindung zur behandlung von thrombose |
| US5424286A (en) | 1993-05-24 | 1995-06-13 | Eng; John | Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same |
| US5733757A (en) | 1995-12-15 | 1998-03-31 | The Scripps Research Institute | Aldolase catalytic antibody |
| ES2237790T3 (es) | 1996-11-12 | 2005-08-01 | Novo Nordisk A/S | Uso de peptidos glp-1. |
| US6723530B1 (en) | 1997-02-05 | 2004-04-20 | Amylin Pharmaceuticals, Inc. | Polynucleotides encoding proexendin, and methods and uses thereof |
| US6326176B1 (en) | 1997-12-18 | 2001-12-04 | The Scripps Research Institute | Aldol condensations by catalytic antibodies |
| JP2003516121A (ja) | 1999-09-27 | 2003-05-13 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 不可逆的に結合するエンジニアリング抗体 |
| US6294374B1 (en) | 1999-10-08 | 2001-09-25 | The Scripps Research Institute | Use of catalytic antibodies for synthesizing epothilone |
| ATE385238T1 (de) * | 2001-06-27 | 2008-02-15 | Probiodrug Ag | Verwendung von dpiv-inhibitoren als therapeutika für krankhafte neurologische zustände |
| JP2005501058A (ja) | 2001-07-31 | 2005-01-13 | ザ ガバメント オブ ザ ユナイテッドステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ ザ ナショナル インステ | Ｇｌｐ−１、ｅｘｅｎｄｉｎ−４、そのペプチド・アナログ及びその使用 |
| US20060205037A1 (en) | 2003-08-28 | 2006-09-14 | Homayoun Sadeghi | Modified transferrin fusion proteins |
| US20060275288A1 (en) * | 2005-01-20 | 2006-12-07 | Grihalde Nelson D | GLP-1 receptor agonist and allosteric modulator monoclonal antibodies and uses thereof |
| KR101193722B1 (ko) | 2006-07-24 | 2013-01-11 | 바이오렉시스 파마슈티칼 코포레이션 | 엑센딘 융합 단백질 |
| TWI428346B (zh) | 2006-12-13 | 2014-03-01 | Imp Innovations Ltd | 新穎化合物及其等對進食行為影響 |
| KR20090091181A (ko) | 2006-12-20 | 2009-08-26 | 리나트 뉴로사이언스 코퍼레이션 | 자가면역 장애의 치료를 위한 티로신 수용체 키나아제 ｂ 작용제 |
| US20090098130A1 (en) | 2007-01-05 | 2009-04-16 | Bradshaw Curt W | Glucagon-like protein-1 receptor (glp-1r) agonist compounds |
| WO2009030771A1 (en) * | 2007-09-05 | 2009-03-12 | Novo Nordisk A/S | Peptides derivatized with a-b-c-d- and their therapeutical use |
-
2009
- 2009-08-19 US US13/392,244 patent/US20120148586A1/en not_active Abandoned
-
2010
- 2010-08-19 BR BR112012004043A patent/BR112012004043A2/pt not_active IP Right Cessation
- 2010-08-19 RU RU2012106200/15A patent/RU2012106200A/ru not_active Application Discontinuation
- 2010-08-19 EP EP10754580A patent/EP2470198A2/en not_active Withdrawn
- 2010-08-19 CN CN2010800481995A patent/CN102596229A/zh active Pending
- 2010-08-19 CA CA2769835A patent/CA2769835A1/en not_active Abandoned
- 2010-08-19 KR KR1020127004905A patent/KR20120050460A/ko not_active Ceased
- 2010-08-19 MX MX2012002463A patent/MX2012002463A/es not_active Application Discontinuation
- 2010-08-19 WO PCT/IB2010/053754 patent/WO2011024110A2/en not_active Ceased
- 2010-08-19 AU AU2010288191A patent/AU2010288191A1/en not_active Abandoned
- 2010-08-19 IN IN961DEN2012 patent/IN2012DN00961A/en unknown
- 2010-08-26 JP JP2010189054A patent/JP2011057670A/ja not_active Withdrawn
-
2012
- 2012-02-06 IL IL217967A patent/IL217967A0/en unknown
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