JP2010539162A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010539162A5 JP2010539162A5 JP2010524824A JP2010524824A JP2010539162A5 JP 2010539162 A5 JP2010539162 A5 JP 2010539162A5 JP 2010524824 A JP2010524824 A JP 2010524824A JP 2010524824 A JP2010524824 A JP 2010524824A JP 2010539162 A5 JP2010539162 A5 JP 2010539162A5
- Authority
- JP
- Japan
- Prior art keywords
- binding protein
- monoclonal antibody
- influenza virus
- avian influenza
- mutant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000023732 binding proteins Human genes 0.000 claims 27
- 108091008324 binding proteins Proteins 0.000 claims 27
- 238000006386 neutralization reaction Methods 0.000 claims 11
- 241000712461 unidentified influenza virus Species 0.000 claims 11
- 238000000034 method Methods 0.000 claims 9
- 230000035772 mutation Effects 0.000 claims 7
- 150000001413 amino acids Chemical class 0.000 claims 5
- 101710121417 Envelope glycoprotein Proteins 0.000 claims 4
- 102100021696 Syncytin-1 Human genes 0.000 claims 4
- 241000700605 Viruses Species 0.000 claims 3
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- 210000004748 cultured cell Anatomy 0.000 claims 2
- 238000001514 detection method Methods 0.000 claims 2
- 210000004408 hybridoma Anatomy 0.000 claims 2
- 230000002285 radioactive effect Effects 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 101710154606 Hemagglutinin Proteins 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 1
- 101710176177 Protein A56 Proteins 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000000185 hemagglutinin Substances 0.000 claims 1
- 230000001900 immune effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000008520 organization Effects 0.000 claims 1
- 238000004321 preservation Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97205907P | 2007-09-13 | 2007-09-13 | |
| US60/972,059 | 2007-09-13 | ||
| PCT/SG2008/000347 WO2009035420A1 (en) | 2007-09-13 | 2008-09-12 | Monoclonal antibodies specific to hemagglutinin and neuraminidase from influenza virus h5-subtype or n1-subtype and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010539162A JP2010539162A (ja) | 2010-12-16 |
| JP2010539162A5 true JP2010539162A5 (OSRAM) | 2012-08-16 |
| JP5490696B2 JP5490696B2 (ja) | 2014-05-14 |
Family
ID=40452269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010524824A Expired - Fee Related JP5490696B2 (ja) | 2007-09-13 | 2008-09-12 | インフルエンザウイルスｈ５亜型またはｎ１亜型からのヘマグルチニンおよびノイラミニダーゼに特異的なモノクローナル抗体ならびにそれらの使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US8383121B2 (OSRAM) |
| EP (2) | EP2947094B1 (OSRAM) |
| JP (1) | JP5490696B2 (OSRAM) |
| CN (2) | CN101883789B (OSRAM) |
| AU (1) | AU2008297594B2 (OSRAM) |
| SG (2) | SG183032A1 (OSRAM) |
| WO (1) | WO2009035420A1 (OSRAM) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2155787A4 (en) * | 2007-05-11 | 2010-06-16 | Temasek Life Sciences Lab Ltd | SPECIFIC TO THE H5-SUBTYPE BINDING PROTEINS SUITED TO THE DIAGNOSIS AND MONITORING OF THE H5 BIRGRAP |
| US8137920B2 (en) * | 2008-03-20 | 2012-03-20 | Abaxis, Inc. | Multi-wavelength analyses of sol-particle specific binding assays |
| SG176003A1 (en) * | 2009-05-11 | 2011-12-29 | Crucell Holland Bv | Human binding molecules capable of neutralizing influenza virus h3n2 and uses thereof |
| EP2563389B1 (en) * | 2010-04-30 | 2015-07-08 | Temasek Life Sciences Laboratory Limited | Universal vaccine against h5n1 lineages |
| WO2012054745A1 (en) * | 2010-10-20 | 2012-04-26 | New York Blood Center, Inc. | Influenza hemagglutinin-specific monoclonal antibodies for preventing and treating influenza virus infection |
| JP2013087069A (ja) * | 2011-10-17 | 2013-05-13 | Toyobo Co Ltd | Ｈ５亜型インフルエンザウイルスを特異的に認識するモノクローナル抗体 |
| US9233152B2 (en) | 2012-01-12 | 2016-01-12 | Temasek Life Sciences Laboratory Limited | Monoclonal antibodies targeting neutralizing epitopes on H5 influenza virus of clade 2.3 |
| TW201346040A (zh) * | 2012-03-30 | 2013-11-16 | Tanaka Precious Metal Ind | 流行性感冒ａ型病毒檢驗用套組 |
| US9969794B2 (en) | 2012-05-10 | 2018-05-15 | Visterra, Inc. | HA binding agents |
| US9637537B2 (en) | 2012-11-19 | 2017-05-02 | Temasek Life Sciences Laboratories Limited | Monoclonal antibodies targeting neutralizing epitopes on H7 influenza viruses |
| CN104407133A (zh) * | 2014-11-03 | 2015-03-11 | 清华大学深圳研究生院 | A型流感病毒检测方法及其试剂盒 |
| TWI702229B (zh) | 2014-12-19 | 2020-08-21 | 美商再生元醫藥公司 | 流行性感冒病毒血球凝集素之人類抗體 |
| US10513553B2 (en) | 2015-11-13 | 2019-12-24 | Visterra, Inc. | Compositions and methods for treating and preventing influenza |
| CA3015347A1 (en) | 2016-02-24 | 2017-08-31 | Visterra, Inc. | Formulations of antibody molecules to influenza virus |
| PL238020B1 (pl) * | 2016-09-12 | 2021-06-28 | Inst Biotechnologii I Antybiotykow | Kompozycja przeciwciał monoklonalnych przeciwko hemaglutyninie wirusów grypy serotypu H5 i jej zastosowanie, hybrydomy produkujące rzeczone przeciwciała, sposób diagnozowania infekcji wirusami grypy serotypu H5 oraz zestawy diagnostyczne |
| CN106399265B (zh) * | 2016-09-19 | 2018-03-02 | 中国动物卫生与流行病学中心 | 一种提高禽流感疫苗毒株增殖滴度的方法 |
| CA3088194A1 (en) | 2018-01-26 | 2019-08-01 | Regeneron Pharmaceuticals, Inc. | Human antibodies to influenza hemagglutinin |
| JP2022521819A (ja) | 2019-03-25 | 2022-04-12 | ビステラ， インコーポレイテッド | インフルエンザを処置および予防するための組成物および方法 |
| CN110483637B (zh) * | 2019-07-22 | 2022-06-10 | 扬州大学 | 一种抗禽流感病毒神经氨酸酶n2单克隆抗体、编码基因及其应用 |
| CN112574297B (zh) * | 2019-09-27 | 2022-06-24 | 上海生物制品研究所有限责任公司 | 抗神经氨酸酶的单克隆抗体及其应用 |
| WO2021201677A1 (en) | 2020-04-01 | 2021-10-07 | Kiadis Pharma Intellectual Property B.V. | Compositions and methods targeting influenza |
| TW202235105A (zh) * | 2020-11-23 | 2022-09-16 | 美商維爾生物科技股份有限公司 | 抗流感抗體及其組合 |
| KR102605065B1 (ko) * | 2021-10-14 | 2023-11-22 | 원광대학교산학협력단 | 고병원성 조류 인플루엔자 바이러스 h5n1에 특이적인 단클론항체 및 이를 이용한 신속 진단 키트 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| WO2007021002A1 (ja) | 2005-08-19 | 2007-02-22 | Bl Co., Ltd. | インフルエンザウイルスｈ５亜型の免疫検出法 |
| US8642513B2 (en) | 2005-09-15 | 2014-02-04 | Crucell Holland B.V. | Method for preparing immunoglobulin libraries |
| CA2637837A1 (en) * | 2006-01-26 | 2007-08-09 | Hx Diagnostics, Inc. | Monoclonal antibodies binding to avian influenza virus subtype h5 haemagglutinin and uses thereof |
| EP2059532B1 (en) * | 2006-09-07 | 2012-12-26 | Crucell Holland B.V. | Human binding molecules capable of neutralizing influenza virus h5n1 and uses thereof |
| EP2155787A4 (en) * | 2007-05-11 | 2010-06-16 | Temasek Life Sciences Lab Ltd | SPECIFIC TO THE H5-SUBTYPE BINDING PROTEINS SUITED TO THE DIAGNOSIS AND MONITORING OF THE H5 BIRGRAP |
| US7879326B2 (en) * | 2007-06-15 | 2011-02-01 | The Board Of Trustees Of The Leland Stanford Junior University | Human neutralizing monoclonal antibodies to H5N1 influenza A virus |
| EP2207804B1 (en) * | 2007-09-13 | 2015-07-22 | Temasek Life Sciences Laboratory Limited | Monoclonal antibodies specific to hemagglutinin from influenza virus h5-subtype and uses thereof |
-
2008
- 2008-09-12 AU AU2008297594A patent/AU2008297594B2/en not_active Ceased
- 2008-09-12 CN CN200880115546.4A patent/CN101883789B/zh not_active Expired - Fee Related
- 2008-09-12 EP EP15176239.0A patent/EP2947094B1/en not_active Not-in-force
- 2008-09-12 WO PCT/SG2008/000347 patent/WO2009035420A1/en not_active Ceased
- 2008-09-12 EP EP08830693.1A patent/EP2201039B1/en not_active Not-in-force
- 2008-09-12 JP JP2010524824A patent/JP5490696B2/ja not_active Expired - Fee Related
- 2008-09-12 US US12/677,971 patent/US8383121B2/en not_active Expired - Fee Related
- 2008-09-12 CN CN201210506817.7A patent/CN103214570B/zh not_active Expired - Fee Related
- 2008-09-12 SG SG2012052106A patent/SG183032A1/en unknown
- 2008-09-12 SG SG2012052098A patent/SG183031A1/en unknown
-
2012
- 2012-09-11 US US13/610,054 patent/US8540996B2/en not_active Expired - Fee Related
- 2012-09-11 US US13/610,021 patent/US8574581B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010539162A5 (OSRAM) | ||
| JP2010526880A5 (OSRAM) | ||
| JP2010539161A5 (OSRAM) | ||
| EP2203477B1 (fr) | Anticorps monoclonaux specifiques de l'hemagglutinine du virus grippal | |
| US10208107B2 (en) | Antibodies directed against influenza | |
| CN101883789B (zh) | 特异于流感病毒h5亚型或者n1亚型的血凝素和神经氨酸酶的单克隆抗体及其应用 | |
| Gravel et al. | Qualitative and quantitative analyses of virtually all subtypes of influenza A and B viral neuraminidases using antibodies targeting the universally conserved sequences | |
| CN101990575A (zh) | 抗h5亚型a型流感病毒血凝素单克隆抗体 | |
| JP2010526880A (ja) | Ｈ５トリインフルエンザの診断および監視に有用なｈ５亜型特異的結合タンパク質 | |
| AU2007310753A1 (en) | Peptide vaccine for influenza virus | |
| JP2005531286A (ja) | ＨＣＶＥ２グリコプロテインに対して向けられ、ｉｎｖｉｔｒｏ中和活性を有するヒトモノクローナル抗体Ｆａｂ断片 | |
| CN104507500A (zh) | 流感中和药剂 | |
| US10696737B2 (en) | Monoclonal antibodies against hemagglutinin of h5-serotype influenza viruses and their uses, hybridomas producing said antibodies, compositions and diagnostic kits | |
| CN101220097A (zh) | H5亚型禽流感病毒血凝素蛋白的单克隆抗体或其结合活性片段及其用途 | |
| US9903874B2 (en) | Method of determining resistance to influenza virus | |
| KR20180038261A (ko) | H7n9 조류 인플루엔자 바이러스 검출을 위한 효소면역 측정키트 | |
| JP2017538786A5 (OSRAM) | ||
| CN101591390B (zh) | 抗h5n1来源的禽流感病毒核蛋白np的单克隆抗体及其应用 | |
| Wu et al. | Quantum dot immunochromatographic strip for rapid and sensitive detection of H5 subtype avian influenza virus | |
| KR20220092744A (ko) | 말 인플루엔자 바이러스 h3n8형에 특이적인 단일클론항체 및 이를 이용한 말인플루엔자 바이러스 검출용 조성물 | |
| US10301359B2 (en) | Human adaptation of H3 influenza | |
| KR102798934B1 (ko) | 사스 코로나바이러스 2 스파이크 항원에 특이적으로 결합하는 항체 및 이의 용도 | |
| KR102798983B1 (ko) | 사스 코로나바이러스 2 스파이크 항원에 특이적으로 결합하는 항체 및 이의 용도 | |
| KR102798975B1 (ko) | 사스 코로나바이러스 2 스파이크 항원에 특이적으로 결합하는 항체 및 이의 용도 | |
| KR20110064174A (ko) | 신종 플루 진단을 위한 신종 인플루엔자 바이러스 ａ／ｈ１ｎ１-특이 단클론 항체 및 그의 용도 |