JP2010538618A - ドナー特異的抗体ライブラリー - Google Patents
ドナー特異的抗体ライブラリー Download PDFInfo
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- C07K16/005—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
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- A61P31/12—Antivirals
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- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
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- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B20/00—Methods specially adapted for identifying library members
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- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
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- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- Chemical & Material Sciences (AREA)
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- Molecular Biology (AREA)
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- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- AIDS & HIV (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/853,795 US8148085B2 (en) | 2006-05-15 | 2007-09-11 | Donor specific antibody libraries |
| PCT/US2008/075998 WO2009036157A1 (en) | 2007-09-11 | 2008-09-11 | Donor specific antibody libraries |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010538618A true JP2010538618A (ja) | 2010-12-16 |
| JP2010538618A5 JP2010538618A5 (enExample) | 2012-11-15 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010524259A Withdrawn JP2010538618A (ja) | 2007-09-11 | 2008-09-11 | ドナー特異的抗体ライブラリー |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8148085B2 (enExample) |
| EP (1) | EP2190477A1 (enExample) |
| JP (1) | JP2010538618A (enExample) |
| CN (1) | CN101854950A (enExample) |
| AU (1) | AU2008298939A1 (enExample) |
| WO (1) | WO2009036157A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2014530008A (ja) * | 2011-09-30 | 2014-11-17 | セルトリオン・インコーポレイテッド | ヒトｂ細胞で生産されたインフルエンザａウイルス中和活性を持つ結合分子 |
| JP2015522289A (ja) * | 2012-07-18 | 2015-08-06 | イルミナ ケンブリッジ リミテッド | ハプロタイプの決定およびハプロタイプのフェージングのための方法およびシステム |
| JP2017537931A (ja) * | 2014-12-05 | 2017-12-21 | セルトリオン， インク． | １以上のインフルエンザウイルス中和結合分子を含むアジュバント組成物およびこれを含むワクチン組成物 |
| JP2019077708A (ja) * | 2011-04-28 | 2019-05-23 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 試料に関連するポリヌクレオチドの同定 |
| KR20190104312A (ko) * | 2016-10-31 | 2019-09-09 | 유니베르시태트 취리히 | 단백질 스크리닝 및 검출 방법 |
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| US7584439B2 (en) * | 2006-12-07 | 2009-09-01 | Agere Systems Inc. | Cell modeling for integrated circuit design with characterization of upstream driver strength |
| EP2413962A1 (en) | 2009-03-30 | 2012-02-08 | Mount Sinai School of Medicine | Influenza virus vaccines and uses thereof |
| WO2010130636A1 (en) * | 2009-05-11 | 2010-11-18 | Crucell Holland B.V. | Human binding molecules capable of neutralizing influenza virus h3n2 and uses thereof |
| CA2761681A1 (en) * | 2009-05-13 | 2010-11-18 | Sea Lane Biotechnologies, Llc | Neutralizing molecules to influenza viruses |
| AU2010254136B2 (en) * | 2009-05-26 | 2016-09-29 | Mount Sinai School Of Medicine | Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof |
| US20110077966A1 (en) * | 2009-09-28 | 2011-03-31 | Augusta E.N.T., P.C. | Allergy electronic medical record system and method |
| AU2011217903B2 (en) | 2010-02-18 | 2017-03-02 | Mount Sinai School Of Medicine | Vaccines for use in the prophylaxis and treatment of influenza virus disease |
| MX2012011300A (es) | 2010-03-30 | 2012-11-29 | Sinai School Medicine | Vacunas del virus de influenza y usos de las mismas. |
| EP2633049B1 (en) * | 2010-10-27 | 2018-10-10 | Harrisvaccines Inc | Methods and compositions to protect aquatic invertebrates from disease |
| US20230287392A1 (en) * | 2011-04-28 | 2023-09-14 | The Board Of Trustees Of The Leland Stanford Junior University | Identification of Polynucleotides Associated with a Sample |
| IN2014CN02114A (enExample) | 2011-09-20 | 2015-05-29 | Sinai School Medicine | |
| UA118441C2 (uk) | 2012-10-08 | 2019-01-25 | Протена Біосаєнсиз Лімітед | Антитіло, що розпізнає альфа-синуклеїн |
| EP4154907A1 (en) | 2012-12-18 | 2023-03-29 | Icahn School of Medicine at Mount Sinai | Influenza virus vaccines and uses thereof |
| WO2014159960A1 (en) | 2013-03-14 | 2014-10-02 | Icahn School Of Medicine At Mount Sinai | Antibodies against influenza virus hemagglutinin and uses thereof |
| AR096601A1 (es) | 2013-06-21 | 2016-01-20 | Novartis Ag | Anticuerpos del receptor 1 de ldl oxidado similar a lectina y métodos de uso |
| US9562101B2 (en) | 2013-06-21 | 2017-02-07 | Novartis Ag | Lectin-like oxidized LDL receptor 1 antibodies and methods of use |
| US9951131B2 (en) | 2013-07-12 | 2018-04-24 | Prothena Biosciences Limited | Antibodies that recognize IAPP |
| US9850302B2 (en) | 2013-07-12 | 2017-12-26 | Prothena Biosciences Limited | Antibodies that recognize IAPP |
| US20150225770A1 (en) * | 2014-02-12 | 2015-08-13 | U.S. Army Research Laboratory Attn: Rdrl-Loc-I | Phenotype-neutral barcodes for digital analysis |
| KR101740030B1 (ko) | 2014-03-07 | 2017-05-29 | 사회복지법인 삼성생명공익재단 | ScFv 항체 라이브러리, 이의 제조방법 및 이를 이용한 ScFv 항체 스크리닝 방법 |
| US20170022291A1 (en) * | 2014-04-01 | 2017-01-26 | Adimab, Llc | Multispecific antibody analogs comprising a common light chain, and methods of their preparation and use |
| WO2015155694A1 (en) | 2014-04-08 | 2015-10-15 | Prothena Biosciences Limited | Blood-brain barrier shuttles containing antibodies recognizing alpha-synuclein |
| JP2018504412A (ja) | 2015-01-23 | 2018-02-15 | アイカーン スクール オブ メディシン アット マウント サイナイ | インフルエンザウイルスワクチン接種レジメン |
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| ZA836080B (en) | 1982-08-23 | 1984-04-25 | Scripps Clinic Res | Broad spectrum influenza antisera |
| US5667988A (en) | 1992-01-27 | 1997-09-16 | The Scripps Research Institute | Methods for producing antibody libraries using universal or randomized immunoglobulin light chains |
| US6337070B1 (en) | 1993-04-29 | 2002-01-08 | Takara Shuzo Co., Ltd. | Polypeptides for use in generating anti-human influenza virus antibodies |
| EP0699750A1 (en) * | 1994-06-07 | 1996-03-06 | Gesellschaft für biotechnologische Forschung mbH (GBF) | A collection of phagemids, a collection of Escherichia coli cells carrying the phagemids, a collection of phagemid particles produced from said collection and phagemid particles obtained according to the process |
| US6169175B1 (en) * | 1997-08-06 | 2001-01-02 | Centers For Disease Control And Prevention | Preparation and use of recombinant influenza A virus M2 construct vaccines |
| US6607878B2 (en) * | 1997-10-06 | 2003-08-19 | Stratagene | Collections of uniquely tagged molecules |
| JP2003536048A (ja) | 1999-03-23 | 2003-12-02 | バイオヴェイション リミテッド | タンパク質の単離および分析 |
| FR2817869B1 (fr) | 2000-12-07 | 2005-01-14 | Technopharm | Anticorps monoclonal humain dirige contre le virus influenza ou un fragment de celui-ci |
| DE60144063D1 (de) | 2000-12-18 | 2011-03-31 | Dyax Corp | Gerichtete bibliotheken die genetisch verpackt sind |
| WO2003052101A1 (en) | 2001-12-14 | 2003-06-26 | Rosetta Inpharmatics, Inc. | Sample tracking using molecular barcodes |
| WO2003078600A2 (en) | 2002-03-13 | 2003-09-25 | Kirin Beer Kabushiki Kaisha | Human monoclonal antibodies to influenza m2 protein and methods of making and using same |
| ATE461292T1 (de) | 2003-09-10 | 2010-04-15 | Althea Technologies Inc | Erstellung von expressionsprofilen unter verwendung von mikroarrays |
| EP1647600A3 (en) | 2004-09-17 | 2006-06-28 | Affymetrix, Inc. (A US Entity) | Methods for identifying biological samples by addition of nucleic acid bar-code tags |
| US8642513B2 (en) | 2005-09-15 | 2014-02-04 | Crucell Holland B.V. | Method for preparing immunoglobulin libraries |
| GB0522460D0 (en) | 2005-11-03 | 2005-12-14 | Prendergast Patrick T | Composition and method for the treatment of avian influenza |
| CA2637837A1 (en) | 2006-01-26 | 2007-08-09 | Hx Diagnostics, Inc. | Monoclonal antibodies binding to avian influenza virus subtype h5 haemagglutinin and uses thereof |
| WO2007134327A2 (en) | 2006-05-15 | 2007-11-22 | Sea Lane Biotechnologies, Llc. | Neutralizing antibodies to influenza viruses |
| MY170607A (en) | 2006-09-07 | 2019-08-20 | Crucell Holland Bv | Human binding molecules capable of neutralizing influenza virus h5n1 and uses thereof |
| EP2132312B1 (en) | 2007-03-27 | 2016-01-27 | Sea Lane Biotechnologies,llc. | Constructs and libraries comprising antibody surrogate light chain sequences |
-
2007
- 2007-09-11 US US11/853,795 patent/US8148085B2/en active Active
-
2008
- 2008-09-11 JP JP2010524259A patent/JP2010538618A/ja not_active Withdrawn
- 2008-09-11 US US12/676,737 patent/US20100291066A1/en not_active Abandoned
- 2008-09-11 WO PCT/US2008/075998 patent/WO2009036157A1/en not_active Ceased
- 2008-09-11 EP EP08830817A patent/EP2190477A1/en not_active Withdrawn
- 2008-09-11 AU AU2008298939A patent/AU2008298939A1/en not_active Abandoned
- 2008-09-11 CN CN200880115462A patent/CN101854950A/zh active Pending
-
2012
- 2012-03-16 US US13/422,313 patent/US20120264647A1/en not_active Abandoned
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019077708A (ja) * | 2011-04-28 | 2019-05-23 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 試料に関連するポリヌクレオチドの同定 |
| JP2014530008A (ja) * | 2011-09-30 | 2014-11-17 | セルトリオン・インコーポレイテッド | ヒトｂ細胞で生産されたインフルエンザａウイルス中和活性を持つ結合分子 |
| JP2015522289A (ja) * | 2012-07-18 | 2015-08-06 | イルミナ ケンブリッジ リミテッド | ハプロタイプの決定およびハプロタイプのフェージングのための方法およびシステム |
| US9977861B2 (en) | 2012-07-18 | 2018-05-22 | Illumina Cambridge Limited | Methods and systems for determining haplotypes and phasing of haplotypes |
| US11257568B2 (en) | 2012-07-18 | 2022-02-22 | Illumina Cambridge Limited | Methods and systems for determining haplotypes and phasing of haplotypes |
| US11605446B2 (en) | 2012-07-18 | 2023-03-14 | Illumina Cambridge Limited | Methods and systems for determining haplotypes and phasing of haplotypes |
| JP2017537931A (ja) * | 2014-12-05 | 2017-12-21 | セルトリオン， インク． | １以上のインフルエンザウイルス中和結合分子を含むアジュバント組成物およびこれを含むワクチン組成物 |
| KR20190104312A (ko) * | 2016-10-31 | 2019-09-09 | 유니베르시태트 취리히 | 단백질 스크리닝 및 검출 방법 |
| KR102264642B1 (ko) | 2016-10-31 | 2021-06-15 | 유니베르시태트 취리히 | 단백질 스크리닝 및 검출 방법 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008298939A1 (en) | 2009-03-19 |
| US20120264647A1 (en) | 2012-10-18 |
| US8148085B2 (en) | 2012-04-03 |
| US20080152657A1 (en) | 2008-06-26 |
| US20100291066A1 (en) | 2010-11-18 |
| EP2190477A1 (en) | 2010-06-02 |
| CN101854950A (zh) | 2010-10-06 |
| WO2009036157A1 (en) | 2009-03-19 |
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