JP2010536786A - ポリカチオンを用いた抗体およびｆｃ融合分子の製剤 - Google Patents

ポリカチオンを用いた抗体およびｆｃ融合分子の製剤 Download PDF

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Publication number
JP2010536786A
JP2010536786A JP2010521190A JP2010521190A JP2010536786A JP 2010536786 A JP2010536786 A JP 2010536786A JP 2010521190 A JP2010521190 A JP 2010521190A JP 2010521190 A JP2010521190 A JP 2010521190A JP 2010536786 A JP2010536786 A JP 2010536786A
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JP
Japan
Prior art keywords
polycation
antibody
formulation
composition
mab
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Withdrawn
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JP2010521190A
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English (en)
Japanese (ja)
Inventor
ボンダレンコ，パベル
リー，テイエンシヨン
スローイー，クリストフアー・ジエイムズ
シアオ，カン
Original Assignee
アムジエン・インコーポレーテツド
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Publication of JP2010536786A publication Critical patent/JP2010536786A/ja
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
JP2010521190A 2007-08-17 2008-08-15 ポリカチオンを用いた抗体およびｆｃ融合分子の製剤 Withdrawn JP2010536786A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95651407P 2007-08-17 2007-08-17
PCT/US2008/073250 WO2009026122A1 (fr) 2007-08-17 2008-08-15 Formulations d'anticorps et de molécules de fusion fc à l'aide de polycations

Publications (1)

Publication Number Publication Date
JP2010536786A true JP2010536786A (ja) 2010-12-02

Family

ID=40014979

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010521190A Withdrawn JP2010536786A (ja) 2007-08-17 2008-08-15 ポリカチオンを用いた抗体およびｆｃ融合分子の製剤

Country Status (6)

Country Link
EP (1) EP2190476A1 (fr)
JP (1) JP2010536786A (fr)
AU (1) AU2008289225A1 (fr)
CA (1) CA2696049A1 (fr)
MX (1) MX2010001723A (fr)
WO (1) WO2009026122A1 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8883979B2 (en) 2012-08-31 2014-11-11 Bayer Healthcare Llc Anti-prolactin receptor antibody formulations
WO2015064591A1 (fr) 2013-10-28 2015-05-07 テルモ株式会社 Suspension aqueuse de protéine
JP2015532657A (ja) * 2012-09-05 2015-11-12 トラコン ファーマシューティカルズ、インコーポレイテッド 抗体製剤及びその使用
US9944714B2 (en) 2009-09-30 2018-04-17 Tracon Pharmaceuticals, Inc. Endoglin antibodies
WO2019022094A1 (fr) * 2017-07-24 2019-01-31 テルモ株式会社 Procédé de production d'un complexe contenant une protéine médicale et un acide polyaminé, et complexe contenant une protéine médicale et un acide polyaminé
JP2020138981A (ja) * 2017-03-01 2020-09-03 メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ モノクローナル抗体製剤

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7767206B2 (en) 2006-10-02 2010-08-03 Amgen Inc. Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto
CN102821787B (zh) 2010-01-15 2015-07-29 麒麟-安姆根有限公司 抗体制剂和治疗方案
CN102585016B (zh) * 2012-03-06 2014-06-04 江苏健德生物药业有限公司 一种可同时抑制t、b淋巴细胞功能的免疫融合蛋白、其制备方法及其应用
CN103232542B (zh) * 2013-02-01 2015-05-13 殷勇 一种双靶标嵌合蛋白
CN110496099B (zh) 2013-09-11 2022-06-21 伊戈尔生物药品股份有限公司 包含粘度降低剂的液体蛋白质制剂
MX2017004306A (es) 2014-10-01 2017-12-20 Eagle Biologics Inc Formulaciones de polisacáridos y ácido nucleico que contienen agentes de reducción de viscosidad.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8904370D0 (en) * 1989-02-25 1989-04-12 Cosmas Damian Ltd Liquid delivery compositions
AU653771B2 (en) * 1991-01-03 1994-10-13 Alkermes Controlled Therapeutics, Inc. Stabilization of proteins by cationic biopolymers
DE4110409C2 (de) * 1991-03-29 1999-05-27 Boehringer Ingelheim Int Neue Protein-Polykation-Konjugate
US5521291A (en) * 1991-09-30 1996-05-28 Boehringer Ingelheim International, Gmbh Conjugates for introducing nucleic acid into higher eucaryotic cells
GB9320782D0 (en) * 1993-10-08 1993-12-01 Univ Leeds Innovations Ltd Stabilising of proteins on solution
US6660843B1 (en) * 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9944714B2 (en) 2009-09-30 2018-04-17 Tracon Pharmaceuticals, Inc. Endoglin antibodies
US8883979B2 (en) 2012-08-31 2014-11-11 Bayer Healthcare Llc Anti-prolactin receptor antibody formulations
JP2015532657A (ja) * 2012-09-05 2015-11-12 トラコン ファーマシューティカルズ、インコーポレイテッド 抗体製剤及びその使用
JP2018076350A (ja) * 2012-09-05 2018-05-17 トラコン ファーマシューティカルズ、インコーポレイテッド 抗体製剤及びその使用
US10195281B2 (en) 2012-09-05 2019-02-05 Tracon Pharmaceuticals, Inc. Antibody formulations and uses thereof
JP2019059753A (ja) * 2012-09-05 2019-04-18 トラコン ファーマシューティカルズ、インコーポレイテッド 抗体製剤及びその使用
WO2015064591A1 (fr) 2013-10-28 2015-05-07 テルモ株式会社 Suspension aqueuse de protéine
JP2019043955A (ja) * 2013-10-28 2019-03-22 テルモ株式会社 タンパク質水性懸濁剤
JP2020138981A (ja) * 2017-03-01 2020-09-03 メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ モノクローナル抗体製剤
WO2019022094A1 (fr) * 2017-07-24 2019-01-31 テルモ株式会社 Procédé de production d'un complexe contenant une protéine médicale et un acide polyaminé, et complexe contenant une protéine médicale et un acide polyaminé
JP2019023175A (ja) * 2017-07-24 2019-02-14 テルモ株式会社 医療用タンパク質とポリアミノ酸とを含む複合体の製造方法および医療用タンパク質とポリアミノ酸とを含む複合体
JP7104929B2 (ja) 2017-07-24 2022-07-22 テルモ株式会社 医療用タンパク質とポリアミノ酸とを含む複合体の製造方法および医療用タンパク質とポリアミノ酸とを含む複合体

Also Published As

Publication number Publication date
CA2696049A1 (fr) 2009-02-26
EP2190476A1 (fr) 2010-06-02
AU2008289225A1 (en) 2009-02-26
WO2009026122A1 (fr) 2009-02-26
MX2010001723A (es) 2010-04-30

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Effective date: 20111101