JP2010535486A - レプチン融合タンパク質 - Google Patents
レプチン融合タンパク質 Download PDFInfo
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- JP2010535486A JP2010535486A JP2010519503A JP2010519503A JP2010535486A JP 2010535486 A JP2010535486 A JP 2010535486A JP 2010519503 A JP2010519503 A JP 2010519503A JP 2010519503 A JP2010519503 A JP 2010519503A JP 2010535486 A JP2010535486 A JP 2010535486A
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- leptin
- acid sequence
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Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0715216.8A GB0715216D0 (en) | 2007-08-03 | 2007-08-03 | Leptin |
| US95636007P | 2007-08-16 | 2007-08-16 | |
| PCT/GB2008/002489 WO2009019427A1 (en) | 2007-08-03 | 2008-07-23 | Leptin fusion proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010535486A true JP2010535486A (ja) | 2010-11-25 |
| JP2010535486A5 JP2010535486A5 (https=) | 2011-09-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010519503A Withdrawn JP2010535486A (ja) | 2007-08-03 | 2008-07-23 | レプチン融合タンパク質 |
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| Country | Link |
|---|---|
| US (1) | US20110092417A1 (https=) |
| EP (1) | EP2185585A1 (https=) |
| JP (1) | JP2010535486A (https=) |
| CN (1) | CN101827858A (https=) |
| GB (1) | GB0715216D0 (https=) |
| WO (1) | WO2009019427A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2630031T3 (es) | 2010-09-28 | 2017-08-17 | Aegerion Pharmaceuticals, Inc. | Un polipéptido de leptina pinnípedo-humano quimérico con solubilidad aumentada |
| ES2732475T3 (es) * | 2011-07-08 | 2019-11-22 | Aegerion Pharmaceuticals Inc | Polipéptidos modificados por ingeniería genética que tienen una duración potenciada de la acción y una inmunogenicidad reducida |
| JP6006309B2 (ja) | 2011-07-08 | 2016-10-12 | アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc | 作用持続期間が増大し、免疫原性が減少した操作されたポリペプチド |
| EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| TW202417497A (zh) | 2015-10-12 | 2024-05-01 | 美商再生元醫藥公司 | 活化瘦素受體的抗原結合蛋白 |
| US10550192B2 (en) | 2016-11-08 | 2020-02-04 | Regeneron Pharmaceuticals, Inc. | Antigen-binding proteins that antagonize leptin receptor |
| WO2019126071A1 (en) | 2017-12-18 | 2019-06-27 | Regeneron Pharmaceuticals, Inc. | Bispecific antigen binding molecules that bind leptin receptor and/or gp130, and methods of use thereof |
| DK3773713T3 (da) | 2018-04-06 | 2025-08-18 | Regeneron Pharma | Leptinreceptoragonistantistof til anvendelse i forøgelse af knoglemasse hos et individ, der lider af metabolisk dysfunktion eller hypoleptinæmI |
| CN109942716B (zh) * | 2019-04-08 | 2023-05-12 | 河南师范大学 | 一种用于治疗代谢疾病的瘦素融合蛋白及其制备方法和应用 |
| CN111848774B (zh) * | 2020-08-05 | 2022-05-10 | 武汉海特生物制药股份有限公司 | 一种美曲普汀的制备方法 |
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| IL122818A0 (en) * | 1997-07-10 | 1998-08-16 | Yeda Res & Dev | Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof |
| JP4660062B2 (ja) * | 2000-06-16 | 2011-03-30 | アステリオン・リミテッド | 結合剤 |
| EP1771467A2 (en) * | 2004-07-26 | 2007-04-11 | Asterion Limited | Linkers |
| WO2007080404A2 (en) * | 2006-01-12 | 2007-07-19 | Asterion Limited | Leptin ligand |
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- 2008-07-23 JP JP2010519503A patent/JP2010535486A/ja not_active Withdrawn
- 2008-07-23 US US12/671,979 patent/US20110092417A1/en not_active Abandoned
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| EP2185585A1 (en) | 2010-05-19 |
| US20110092417A1 (en) | 2011-04-21 |
| GB0715216D0 (en) | 2007-09-12 |
| WO2009019427A1 (en) | 2009-02-12 |
| CN101827858A (zh) | 2010-09-08 |
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