JP2010533645A5 - - Google Patents

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Publication number
JP2010533645A5
JP2010533645A5 JP2010510368A JP2010510368A JP2010533645A5 JP 2010533645 A5 JP2010533645 A5 JP 2010533645A5 JP 2010510368 A JP2010510368 A JP 2010510368A JP 2010510368 A JP2010510368 A JP 2010510368A JP 2010533645 A5 JP2010533645 A5 JP 2010533645A5
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JP
Japan
Prior art keywords
cdcl
nmr
mhz
alkyl
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010510368A
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English (en)
Japanese (ja)
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JP2010533645A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/006913 external-priority patent/WO2008150492A1/en
Publication of JP2010533645A publication Critical patent/JP2010533645A/ja
Publication of JP2010533645A5 publication Critical patent/JP2010533645A5/ja
Pending legal-status Critical Current

Links

JP2010510368A 2007-05-31 2008-05-30 脂肪酸アミドヒドロラーゼの三環系阻害剤 Pending JP2010533645A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93249407P 2007-05-31 2007-05-31
PCT/US2008/006913 WO2008150492A1 (en) 2007-05-31 2008-05-30 Tricyclic inhibitors of fatty acid amide hydrolase

Publications (2)

Publication Number Publication Date
JP2010533645A JP2010533645A (ja) 2010-10-28
JP2010533645A5 true JP2010533645A5 (enExample) 2012-07-05

Family

ID=40094018

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010510368A Pending JP2010533645A (ja) 2007-05-31 2008-05-30 脂肪酸アミドヒドロラーゼの三環系阻害剤

Country Status (6)

Country Link
US (1) US8124778B2 (enExample)
EP (1) EP2161997A4 (enExample)
JP (1) JP2010533645A (enExample)
AU (1) AU2008260496A1 (enExample)
CA (1) CA2689148A1 (enExample)
WO (1) WO2008150492A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2689148A1 (en) 2007-05-31 2008-12-11 The Scripps Research Institute Tricyclic inhibitors of fatty acid amide hydrolase
AU2015268638B2 (en) * 2009-10-02 2017-08-31 Avexxin As Anti inflammatory 2-oxothiazoles and 2-oxooxazoles
EP2482815B1 (en) * 2009-10-02 2018-05-02 Avexxin AS Antiinflammatory 2-oxothiazoles and 2-oxooxazoles
WO2011085216A2 (en) 2010-01-08 2011-07-14 Ironwood Pharmaceuticals, Inc. Use of faah inhibitors for treating parkinson's disease and restless legs syndrome
US20130224151A1 (en) 2010-03-31 2013-08-29 United States Of America Use of FAAH Inhibitors for Treating Abdominal, Visceral and Pelvic Pain
BR112012023971A2 (pt) * 2010-04-22 2016-11-29 Merck Sharp & Dohme composto, composição farmacêutica, e, uso de um composto.
EP2951164B1 (en) 2013-01-29 2019-06-05 Avexxin AS Antiinflammatory and antitumor 2-oxothiazoles compounds
GB201413695D0 (en) 2014-08-01 2014-09-17 Avexxin As Compound
CN104592144B (zh) * 2015-01-12 2017-02-22 上海鼎雅药物化学科技有限公司 制备噁唑衍生物的新方法
GB201604318D0 (en) 2016-03-14 2016-04-27 Avexxin As Combination therapy
EP3762034B1 (en) 2018-03-05 2025-08-27 Wylder Nation Foundation A fatty acid amide hydrolase (faahi) inhibitor for use in inhibiting the cellular accumulation of a sphingolipid in a subject that has lysosomal storage disease or disorder
CN110804048A (zh) * 2019-11-08 2020-02-18 暨南大学 恶唑酮类化合物及其应用、faah的正电子药物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6462054B1 (en) * 2000-03-27 2002-10-08 The Scripps Research Institute Inhibitors of fatty acid amide hydrolase
EA010267B1 (ru) * 2002-10-07 2008-06-30 Те Риджентс Оф Те Юниверсити Оф Калифорния Модуляция тревоги через блокаду гидролиза анандамида
CN1703407A (zh) * 2002-10-08 2005-11-30 斯克里普斯研究学院 脂肪酸酰胺水解酶抑制剂
WO2006044617A1 (en) * 2004-10-15 2006-04-27 The Scripps Research Institute Oxadiazole ketone inhibitors of fatty acid amide hydrolase
US20060167075A1 (en) * 2005-01-25 2006-07-27 Pearson James P Modulators of FAAH
EP1983994B1 (en) 2006-02-17 2015-09-30 The Scripps Research Institute Oxazole ketones as modulators of fatty acid amide hydrolase
US8372823B2 (en) * 2007-05-25 2013-02-12 The Scripps Research Institute Tetracyclic inhibitors of fatty acid amide hydrolase
CA2689148A1 (en) 2007-05-31 2008-12-11 The Scripps Research Institute Tricyclic inhibitors of fatty acid amide hydrolase

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