JP2010532765A5 - - Google Patents
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- Publication number
- JP2010532765A5 JP2010532765A5 JP2010515319A JP2010515319A JP2010532765A5 JP 2010532765 A5 JP2010532765 A5 JP 2010532765A5 JP 2010515319 A JP2010515319 A JP 2010515319A JP 2010515319 A JP2010515319 A JP 2010515319A JP 2010532765 A5 JP2010532765 A5 JP 2010532765A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- pharmaceutical composition
- treatment
- biofilm
- development
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003112 inhibitor Substances 0.000 claims 13
- 239000008194 pharmaceutical composition Substances 0.000 claims 12
- 239000000203 mixture Substances 0.000 claims 7
- 229920001184 polypeptide Polymers 0.000 claims 7
- 102000004196 processed proteins & peptides Human genes 0.000 claims 7
- 108090000765 processed proteins & peptides Proteins 0.000 claims 7
- 241000605862 Porphyromonas gingivalis Species 0.000 claims 6
- 239000005557 antagonist Substances 0.000 claims 6
- 230000032770 biofilm formation Effects 0.000 claims 4
- 208000015181 infectious disease Diseases 0.000 claims 4
- 230000002401 inhibitory effect Effects 0.000 claims 4
- 230000002265 prevention Effects 0.000 claims 4
- 208000028169 periodontal disease Diseases 0.000 claims 3
- 102000019259 Succinate Dehydrogenase Human genes 0.000 claims 2
- 108010012901 Succinate Dehydrogenase Proteins 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 239000003242 anti bacterial agent Substances 0.000 claims 2
- 230000003115 biocidal effect Effects 0.000 claims 2
- 230000001629 suppression Effects 0.000 claims 2
- NVEPPWDVLBMNMB-SNAWJCMRSA-N 1-methyl-2-[(e)-2-(3-methylthiophen-2-yl)ethenyl]-5,6-dihydro-4h-pyrimidine Chemical compound CN1CCCN=C1\C=C\C1=C(C)C=CS1 NVEPPWDVLBMNMB-SNAWJCMRSA-N 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 229960005121 morantel Drugs 0.000 claims 1
- VRYKTHBAWRESFI-VOTSOKGWSA-N oxantel Chemical compound CN1CCCN=C1\C=C\C1=CC=CC(O)=C1 VRYKTHBAWRESFI-VOTSOKGWSA-N 0.000 claims 1
- 229960000535 oxantel Drugs 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- WJCNZQLZVWNLKY-UHFFFAOYSA-N thiabendazole Chemical compound S1C=NC(C=2NC3=CC=CC=C3N=2)=C1 WJCNZQLZVWNLKY-UHFFFAOYSA-N 0.000 claims 1
- 229960004546 thiabendazole Drugs 0.000 claims 1
- 235000010296 thiabendazole Nutrition 0.000 claims 1
- 239000004308 thiabendazole Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2007903788A AU2007903788A0 (en) | 2007-07-12 | Biofilm treatment | |
| AU2007903788 | 2007-07-12 | ||
| PCT/AU2008/001017 WO2009006699A1 (en) | 2007-07-12 | 2008-07-11 | Biofilm treatment |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010532765A JP2010532765A (ja) | 2010-10-14 |
| JP2010532765A5 true JP2010532765A5 (https=) | 2011-08-25 |
| JP5476297B2 JP5476297B2 (ja) | 2014-04-23 |
Family
ID=40228120
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010515319A Expired - Fee Related JP5476297B2 (ja) | 2007-07-12 | 2008-07-11 | バイオフィルム治療 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8241611B2 (https=) |
| EP (2) | EP2638905B1 (https=) |
| JP (1) | JP5476297B2 (https=) |
| KR (2) | KR101614938B1 (https=) |
| CN (2) | CN101842097B (https=) |
| AU (1) | AU2008274906B2 (https=) |
| CA (1) | CA2693695C (https=) |
| DK (1) | DK2175851T3 (https=) |
| ES (2) | ES2432690T3 (https=) |
| NZ (2) | NZ595252A (https=) |
| PL (1) | PL2175851T3 (https=) |
| SG (1) | SG183016A1 (https=) |
| WO (1) | WO2009006699A1 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPO652897A0 (en) | 1997-04-30 | 1997-05-29 | University Of Melbourne, The | Synthetic peptide constructs for the diagnosis and treatment of periodontitis |
| US8129500B2 (en) * | 1997-12-10 | 2012-03-06 | Csl Limited | Porphyromonas gingivalis polypeptides and nucleotides |
| CA2652957A1 (en) | 2006-06-27 | 2008-01-03 | Oral Health Australia Pty Ltd. | Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease |
| WO2009006699A1 (en) | 2007-07-12 | 2009-01-15 | Oral Health Australia Pty Ltd | Biofilm treatment |
| US20100297179A1 (en) | 2007-07-12 | 2010-11-25 | Stuart Geoffrey Dashper | Immunology Treatment for Biofilms |
| DK2328914T3 (en) | 2008-08-29 | 2017-07-10 | Oral Health Australia Pty Ltd | Prevention, treatment and diagnosis of P. gingivalis infection |
| AR076179A1 (es) * | 2009-04-01 | 2011-05-26 | Colgate Palmolive Co | Composicion dentifrica no acuosa con vidrio bioaceptable y bioactivo y metodos de uso y fabricacion de la misma |
| US8140041B2 (en) * | 2009-08-27 | 2012-03-20 | Mediatek Inc. | Tunable capacitive device with linearization technique employed therein |
| US8974805B2 (en) * | 2010-02-26 | 2015-03-10 | Nano Intelligent Biomedical Engineering Corporation | Dental cleanser composition for improving adhesion to teeth |
| MY162557A (en) | 2010-02-26 | 2017-06-15 | Oral Health Australia Pty Ltd | Treatment or prevention of infection |
| US20120052052A1 (en) * | 2010-08-27 | 2012-03-01 | The Regents Of The University Of Michigan | Control of biofilm formation |
| US9549904B2 (en) | 2012-06-06 | 2017-01-24 | Thomas Bryan | Method of destroying bacterial biofilm using sterile intravenous or intracavernous glycerin |
| US9480669B2 (en) | 2015-01-06 | 2016-11-01 | The Regents Of The University Of California | Method of destroying and preventing bacterial and fungal biofilm by amino acid infusion |
| US11274144B2 (en) | 2013-06-13 | 2022-03-15 | Research Institute At Nationwide Children's Hospital | Compositions and methods for the removal of biofilms |
| US11248040B2 (en) | 2013-09-26 | 2022-02-15 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
| US9795809B2 (en) | 2013-12-23 | 2017-10-24 | Embro Corporation | Use of moss to improve dental health |
| US20180207067A1 (en) | 2015-07-14 | 2018-07-26 | Research Institute at Nationwide Children's Hospit al | Novel formulation for the elimination of cariogenic and opportunistic pathogens within the oral cavity |
| WO2017023863A1 (en) | 2015-07-31 | 2017-02-09 | Research Institute At Nationwide Children's Hospital | Peptides and antibodies for the removal of biofilms |
| EP3365027B1 (en) | 2015-10-14 | 2022-03-30 | Research Institute at Nationwide Children's Hospital | Hu specific antibodies and their use in inhibiting biofilm |
| JP7661008B2 (ja) | 2017-01-04 | 2025-04-14 | リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル | バイオフィルム関連障害の処置のための抗体断片 |
| US11564982B2 (en) | 2017-01-04 | 2023-01-31 | Research Institute At Nationwide Children's Hospital | DNABII vaccines and antibodies with enhanced activity |
| US11382885B2 (en) | 2017-06-07 | 2022-07-12 | The Regents Of The University Of California | Compositions for treating fungal and bacterial biofilms and methods of using the same |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| AU2019354829B2 (en) | 2018-10-05 | 2025-04-17 | Research Institute At Nationwide Children's Hospital | Hmgb1 protein derivatives for the removal of biofilms |
| US12226386B2 (en) | 2018-12-03 | 2025-02-18 | The Regents Of The University Of California | Compositions and methods for treating biofilms |
| US12109176B1 (en) | 2023-04-20 | 2024-10-08 | Thomas Bryan | Effect of glycerol on biofilm forming bacteria and fungi that changes the microbes sensitivity to pro and anti-biofilm non-toxic, non-bonded plasma amino acids and amino acid derivatives |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4837151A (en) * | 1980-05-19 | 1989-06-06 | The Board Of Trustees Of The Leland Stanford Junior University, Stanford University | Live vaccines comprising two mutations and foreign antigen |
| US5210035A (en) * | 1980-05-19 | 1993-05-11 | Board Of Trustees Of Leland Stanford Jr. University | Non-reventing live vaccines |
| US4735801A (en) * | 1982-09-07 | 1988-04-05 | Board Of Trustees Of Leland Stanford Jr. University | Novel non-reverting salmonella live vaccines |
| US4603112A (en) * | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
| US5830710A (en) | 1988-09-08 | 1998-11-03 | University Of Florida | Cloned porphyromonas gingivalis genes and probes for the detection of periodontal disease |
| WO1994027606A1 (en) * | 1993-05-28 | 1994-12-08 | Unisearch Limited | Method of treating helicobacter pylori infection |
| WO1995000110A1 (en) * | 1993-06-28 | 1995-01-05 | Lion Corporation | Composition for oral cavity |
| US5475097A (en) | 1993-10-21 | 1995-12-12 | University Of Georgia Research Foundation, Inc. | Lysine-specific Porphyromonas gingivalis proteinase |
| WO1995007286A1 (en) | 1993-09-10 | 1995-03-16 | University Of Georgia Research Foundation, Inc. | Porphyromonas gingivalis arginine-specific proteinase coding sequences |
| US5523390A (en) * | 1993-09-10 | 1996-06-04 | University Of Georgia Research Foundation, Inc. | Porphyromonas gingivalis arginine-specific proteinase |
| US6017532A (en) * | 1993-09-10 | 2000-01-25 | University Of Georgia Research Foundation, Inc. | Porphyromonas gingivalis arginine-specific proteinase |
| JPH0797395A (ja) | 1993-09-28 | 1995-04-11 | Kyowa Medex Co Ltd | ポルフイロモナス・ジンジバリス線毛蛋白質の配列を含有するペプチド類及びその用途 |
| DE69527514T2 (de) | 1994-03-29 | 2003-04-03 | Kyowa Hakko Kogyo Co., Ltd. | Gen eines zelloberflächenpolypeptids |
| AUPN627595A0 (en) * | 1995-10-30 | 1995-11-23 | University Of Melbourne, The | Diagnostics and treatments of periodontal disease |
| CA2249994A1 (en) | 1996-03-22 | 1997-09-25 | University Of Georgia Research Foundation, Inc. | Immunogenic compositions comprising porphyromonas gingivalis peptides and methods |
| AUPN901296A0 (en) * | 1996-03-29 | 1996-04-26 | University Of Melbourne, The | Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis |
| US7341727B1 (en) * | 1996-05-03 | 2008-03-11 | Emergent Product Development Gaithersburg Inc. | M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same |
| AUPO652897A0 (en) * | 1997-04-30 | 1997-05-29 | University Of Melbourne, The | Synthetic peptide constructs for the diagnosis and treatment of periodontitis |
| ES2377751T3 (es) | 1997-12-10 | 2012-03-30 | Csl Limited | Polipéptidos y polinucleótidos de Porfiromonas gingivalis |
| AUPP083997A0 (en) * | 1997-12-10 | 1998-01-08 | Csl Limited | Porphyromonas gingivalis nucleotides |
| US8129500B2 (en) * | 1997-12-10 | 2012-03-06 | Csl Limited | Porphyromonas gingivalis polypeptides and nucleotides |
| US6444799B1 (en) * | 1997-12-31 | 2002-09-03 | Csl Limited | P. gingivalis polynucleotides and uses thereof |
| AUPP893999A0 (en) * | 1999-03-01 | 1999-03-25 | Csl Limited | Synthetic peptides containing protective epitopes for the treatment and prevention of periodontitis associated with porphyromonas gingivalis |
| WO2000067917A1 (en) | 1999-05-12 | 2000-11-16 | The General Hospital Corporation | Permeabilizing biofilms |
| GB9913437D0 (en) | 1999-06-09 | 1999-08-11 | Medical Res Council | Fusion proteins |
| AUPQ485999A0 (en) * | 1999-12-24 | 2000-02-03 | Csl Limited | P. gingivalis antigenic composition |
| AUPQ718200A0 (en) * | 2000-04-28 | 2000-05-25 | Csl Limited | Porphyromonas gingivalis recombinant proteins and truncations |
| US6726898B2 (en) * | 2000-11-17 | 2004-04-27 | Gary R. Jernberg | Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease |
| US6576226B1 (en) * | 2000-11-17 | 2003-06-10 | Gary R. Jernberg | Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease |
| US20030083287A1 (en) * | 2000-11-30 | 2003-05-01 | Burgess Nicola A. | ginS |
| AUPR575401A0 (en) * | 2001-06-18 | 2001-07-12 | Unisearch Limited | Method of causing sloughing |
| GB2381449A (en) * | 2001-10-31 | 2003-05-07 | Smithkline Beecham Plc | Oral hygiene compositions comprising an electron acceptor |
| JP2003192616A (ja) | 2001-12-27 | 2003-07-09 | Univ Nihon | 歯周病用ｄｎａワクチン |
| JP2003286191A (ja) | 2002-03-27 | 2003-10-07 | Univ Nihon | 歯周病用粘膜免疫ワクチン |
| WO2004083425A1 (ja) * | 2003-03-17 | 2004-09-30 | Kirin Beer Kabushiki Kaisha | 歯周病治療剤 |
| EP2426140A1 (en) * | 2003-08-15 | 2012-03-07 | University of Florida Research Foundation, Inc. | Identification of porphyromonas gingivalis virulence polynucleotides in the diagnosis, treatment, and monitoring periodontal diseases |
| US7424370B2 (en) * | 2004-02-06 | 2008-09-09 | Council Of Scientific And Industrial Research | Computational method for identifying adhesin and adhesin-like proteins of therapeutic potential |
| US20070098649A1 (en) * | 2004-03-22 | 2007-05-03 | The Board Of Trustees Of The University Of Illinois | Method and composition for controlling oral pathogens |
| EP1799705A4 (en) * | 2004-09-23 | 2008-11-05 | Univ Melbourne | Antigenic complex for the diagnosis and treatment of porphyromonas gingivalis infection |
| WO2008016385A2 (en) | 2006-01-20 | 2008-02-07 | The University Of Washington | Deacylase polypeptides, deacylase polynucleotides, and methods of use thereof |
| CA2652957A1 (en) * | 2006-06-27 | 2008-01-03 | Oral Health Australia Pty Ltd. | Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease |
| WO2008124646A2 (en) | 2007-04-06 | 2008-10-16 | The Government Of The U.S.A, As Represented By The Secretary, Dept. Of Health And Human Services | Use of amyloid proteins as vaccine scaffolds |
| US20100297179A1 (en) * | 2007-07-12 | 2010-11-25 | Stuart Geoffrey Dashper | Immunology Treatment for Biofilms |
| WO2009006699A1 (en) | 2007-07-12 | 2009-01-15 | Oral Health Australia Pty Ltd | Biofilm treatment |
| DK2328914T3 (en) | 2008-08-29 | 2017-07-10 | Oral Health Australia Pty Ltd | Prevention, treatment and diagnosis of P. gingivalis infection |
| KR20120027535A (ko) * | 2009-06-19 | 2012-03-21 | 오럴 헬스 오스트레일리아 피티와이 엘티디 | 카제인 유래 프로테아제 저해 펩타이드 |
-
2008
- 2008-07-11 WO PCT/AU2008/001017 patent/WO2009006699A1/en not_active Ceased
- 2008-07-11 EP EP13162489.2A patent/EP2638905B1/en not_active Not-in-force
- 2008-07-11 CN CN2008801046202A patent/CN101842097B/zh not_active Expired - Fee Related
- 2008-07-11 JP JP2010515319A patent/JP5476297B2/ja not_active Expired - Fee Related
- 2008-07-11 ES ES08772643T patent/ES2432690T3/es active Active
- 2008-07-11 SG SG2012050845A patent/SG183016A1/en unknown
- 2008-07-11 PL PL08772643T patent/PL2175851T3/pl unknown
- 2008-07-11 NZ NZ595252A patent/NZ595252A/xx not_active IP Right Cessation
- 2008-07-11 DK DK08772643.6T patent/DK2175851T3/da active
- 2008-07-11 AU AU2008274906A patent/AU2008274906B2/en not_active Ceased
- 2008-07-11 CN CN2013101796606A patent/CN103357014A/zh active Pending
- 2008-07-11 NZ NZ582474A patent/NZ582474A/en not_active IP Right Cessation
- 2008-07-11 KR KR1020107003308A patent/KR101614938B1/ko not_active Expired - Fee Related
- 2008-07-11 EP EP08772643.6A patent/EP2175851B1/en not_active Not-in-force
- 2008-07-11 CA CA2693695A patent/CA2693695C/en not_active Expired - Fee Related
- 2008-07-11 US US12/668,652 patent/US8241611B2/en not_active Expired - Fee Related
- 2008-07-11 ES ES13162489T patent/ES2714008T3/es active Active
-
2012
- 2012-07-13 US US13/548,454 patent/US8895019B2/en not_active Expired - Fee Related
-
2016
- 2016-01-20 KR KR1020160006951A patent/KR20160013240A/ko not_active Ceased
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