JP2010528757A - Method for obtaining central aortic systolic pressure, and method for obtaining arterial waveform data by analyzing arterial waveform data - Google Patents

Abstract

A method for obtaining central aortic systolic pressure comprising: a) creating a set representing an arterial waveform having a predetermined number of blood pressure measurements; b) determining an integer interval value; c) within the set Averaging a series of consecutive blood pressure measurement readings in a set equal to an integer interval value starting from the f th blood pressure measurement; d) storing the averaged value in a central aortic systolic pressure set; e) setting the central aortic systolic pressure as the highest value in the central aortic pressure set; and c. And d. A method of obtaining central aortic systolic pressure, wherein f is incremented by 1 each time until the value of f plus an integer interval value equals a predetermined number of blood pressure measurements in the set.
[Selection] Figure 1

Description

  The present invention relates to a method for obtaining central aortic systolic pressure and a method for obtaining arterial waveform data by analyzing arterial waveform data. According to the first method of the present invention, the present invention is particularly suitable for obtaining the central aortic systolic pressure from the arterial waveform. However, according to the second method of the present invention, the present invention is suitable for analyzing an arterial waveform data set to obtain a corresponding central aortic systolic pressure data set.

  The following discussion of the background of the invention is intended to facilitate an understanding of the invention. However, the following discussion acknowledges or acknowledges that any of the materials referred to has been published, known, or part of known general knowledge in any jurisdiction at the priority date of this application. It should be understood that it does not.

  Heart disease is a serious health problem in developed countries. One indicator of potential heart disease is the difference in the blood pressure of a living body from a specified range of “normal” values.

  A common method of determining the blood pressure of a living body is to read the upper arm blood pressure (both systolic and diastolic) of the living body using a pressure cuff. These values are then generally used as a substitute central aortic pressure value. Although this assumption has historically proven to be useful in suggesting potential heart disease, recent studies have shown that “normal” brachial blood pressure measured in this manner is an abnormal center. It has been shown that aortic systolic pressure values may be masked.

  One solution to this problem has been adopted by Atcor Medical Pty Ltd of Australia, New South Wales and West Ryde. Atcor's solution transforms the radial pressure waveform into a central aortic blood pressure waveform using an intellectual property variant. However, this formula is only available through intellectual property software marketed by Atcor for use with Atcor's SphygmoCor ™ blood pressure monitoring system. More importantly, the formula is based on the correlation value determined through a cross-representation of patients test, and thus in the region between cross-representative samples. Failure to enter may cause an error in the patient's central aortic pressure reading.

  Throughout this document, unless otherwise indicated, the terms “comprising”, “consisting of” and the like should not be construed as exhaustive, in other words “including” Should be interpreted as “including, but not limited to”.

  In the context of this description of embodiments of the invention, the term “living body” is a reference to the body at the time of occurrence of the arterial waveform. The present invention is not limited to only excluding the calculation of the central aortic pressure value from the arterial waveform of a subsequently deceased patient.

According to a first aspect of the present invention, a method for obtaining central aortic systolic pressure comprising:
a) creating a set representing an arterial waveform having a predetermined number of blood pressure measurements;
b) determining an integer interval value;
c) averaging a series of continuous blood pressure measurement readings in the set equal to an integer interval value starting from the f th blood pressure measurement in the set;
d) storing the averaged value in a central aortic systolic pressure set;
e) setting the central aortic systolic pressure as the highest value in the central aortic pressure set;
Step c. And d. Is repeated, starting with a value of f and incrementing the value of f by 1 each time until the value of f plus an integer interval value equals a predetermined number of blood pressure measurements in the set. There are ways to obtain aortic systolic pressure.

The set of blood pressure measurements should approximately match the uniform distribution of values from the arterial waveform. Specifically, the method preferably includes determining the duration of the arterial waveform. The waveform duration can then be used to determine a predetermined number according to the following equation:
Predetermined number = sr × t
Where
sr = sample rate (Hz) of the measuring device used to record blood pressure measurements in the set,
t = arterial waveform duration.

  The integer interval value may be a sample rate division. Ideally, however, the integer interval value is the sample rate divided by four.

Alternatively, the integer interval value can be a predetermined number of divisions of the blood pressure measurement values in the set of blood pressure measurement values. Ideally, using this technique, integer interval values can fall within a range whose boundaries are determined as follows:
i _range = n / (t × v) ± (n / (t × 30))
Where
n is a predetermined number of blood pressure measurements in the set;
t is the waveform duration (in seconds);
v is a predetermined division value.

  When calculating the aforementioned range, the value of v is preferably set to 4, but is not essential.

  In an alternative configuration, the integer interval value is equal to 60 divided by a predetermined division value. In another alternative configuration, the integer interval value is 15.

  The predetermined number of blood pressure measurements in the set is 15 or more. However, it is preferred that the predetermined number of blood pressure measurements in the set is at least 30.

  In its most preferred arrangement, the predetermined number of blood pressure measurements in the set is at least 30 and the interval is 15.

According to a second aspect of the present invention, a method for obtaining arterial waveform data to obtain a central aortic systolic pressure value, comprising:
a. Receiving an arterial waveform data set;
b. Dividing each arterial waveform in the arterial waveform data set into a representative set of blood pressure measurements having a predetermined number;
c. Determining an integer interval value for the set being processed;
d. Averaging a series of continuous blood pressure measurement readings in the set equal to an integer interval value starting from the fth blood pressure measurement in the set;
e. Storing the averaged value in a central aortic systolic pressure set;
f. Storing the highest value in the central aortic pressure set in the central aortic systolic pressure value set at a position corresponding to the position that the arterial waveform being processed occupies in the arterial waveform data set;
Step b. ~ F. Is repeated for each arterial waveform in the arterial waveform data set, with step d. And e. In addition, the value of f is incremented by 1 each time, starting with a value of f and adding an integer interval value to the value of f equals a predetermined number of blood pressure measurements in the set being processed. There is a method in which the arterial waveform data is repeatedly analyzed to obtain a central aortic systolic pressure value.

According to a third aspect of the present invention, a method for obtaining arterial waveform data to obtain a central aortic systolic pressure value, comprising:
a. Receiving an arterial waveform data set, wherein each arterial waveform in the data set includes a representative set of blood pressure measurements having a predetermined number;
b. Determining an integer interval value for the set being processed;
c. Averaging a series of continuous blood pressure measurement readings in the set equal to an integer interval value starting from the fth blood pressure measurement in the set;
d. Storing the averaged value in a central aortic systolic pressure set;
e. Storing the highest value in the central aortic pressure set in the central aortic systolic pressure value set at a position corresponding to the position that the arterial waveform being processed occupies in the arterial waveform data set;
Step b. ~ E. Are repeated for each arterial waveform in the arterial waveform data set, with step c. And d. In addition, the value of f is incremented by 1 each time, starting with a value of f and adding an integer interval value to the value of f equals a predetermined number of blood pressure measurements in the set being processed. There is a method in which the arterial waveform data is repeatedly analyzed to obtain a central aortic systolic pressure value.

  The predetermined number of blood pressure measurements for at least one arterial waveform in the data set may be different from the predetermined number of blood pressure measurements for other arterial waveforms in the data set.

  For both the second and third aspects of the invention, the set of blood pressure measurements should approximately match the uniform distribution of values from the arterial waveform.

Ideally, the method further comprises determining the duration of the arterial waveform. The waveform duration can then be used to determine a predetermined number according to the following equation:
Predetermined number = sr × t
Where
sr = sample rate (Hz) of the measuring device used to record blood pressure measurements in the set,
t = arterial waveform duration.

  The integer interval value can be a division of the sample rate (sr). Preferably, the integer interval value is the sample rate divided by 4.

Alternatively, the integer interval value can be a predetermined number of divisions of the blood pressure measurement values in the set of blood pressure measurement values. Ideally, using this technique, integer interval values are within the range whose boundaries are determined as follows:
i _range = n / (t × v) ± (n / t × 30))
Where
n is a predetermined number of blood pressure measurements in the set;
t = waveform duration (seconds),
v is a predetermined division value.

  In this equation, it is more preferable that the value of v is set to 4.

  In an alternative configuration, the integer interval value is equal to 60 divided by a predetermined division value. In another alternative configuration, the integer interval value is 15.

  The predetermined number of blood pressure measurements in the set should be 15 or more. A set of 30 blood pressure measurements is preferred.

According to a fourth aspect of the invention,
An arterial waveform measuring device;
A system for obtaining central aortic systolic pressure comprising a processing unit,
The arterial waveform measurement device acquires blood pressure measurements at predetermined intervals until at least one arterial waveform is represented by the acquired set of blood pressure measurements, and then a set of blood pressure measurements representing one arterial waveform is obtained. Is transmitted to the processing unit.
a) determine an integer interval value;
b) averaging a series of continuous blood pressure measurement readings in the set equal to an integer interval value starting from the f th blood pressure measurement in the set;
c) store the averaged value in the central aortic systolic pressure set;
d) Set the central aortic systolic pressure as the highest value in the central aortic pressure set;
Step b. And c. Starts with a value of f and repeats with the value of f incremented by 1 each time until the value of f plus an integer interval value equals the number of blood pressure measurements in the set. There are systems that obtain systolic pressure.

  According to other aspects of the invention, there is a computer readable medium having software thereon for performing the methods described in the first, second and third aspects of the invention.

  The present invention will be described below by way of example only with reference to the accompanying drawings.

It is a flowchart of the method of determining the central aortic pressure of the biological body by the 1st Embodiment of this invention. 6 is a flowchart of a method for analyzing an arterial waveform data set to produce a corresponding central aortic pressure data set according to a second embodiment of the present invention. FIG. 6 is a diagram illustrating an example of an arterial waveform that can be processed by any embodiment of the present invention to obtain a central aortic pressure value.

  Specific embodiments of the present invention will now be described with reference to the accompanying drawings. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the scope of the invention. Moreover, unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.

  According to a first embodiment of the invention, there is a method 10 for determining central aortic pressure. The method 10 is shown in flowchart form in FIG.

  As shown in FIG. 1, the method 10 begins with the creation of a set of blood pressure measurements from a living body (step 12) representing an arterial waveform. The set of blood pressure measurement values has a predetermined number of measurement values (n). In step 14, the predetermined number n is divided by the preset value (v) to determine an integer interval value (i). In this way, an absolute value or a rounded mathematical function can be performed on the integer interval value (i).

Then, starting from the first blood pressure measurement bp [(f)], the following steps are repeated:
Blood pressure measurement values {bp [f], bp [f + 1], bp [f + 2], bp [f + 3],. . . , Bp [f + i−1]} (step 16) to obtain the value s;
The total value s is divided by the interval value i to obtain an average blood pressure value (a) (step 18).
The average blood pressure value a is stored in a central aortic pressure set of a plurality of values (step 20).

  The above steps (steps 16 to 20) are repeated until f + i-1 is equal to n.

  Step 22 examines the analyzed multiple value central aortic pressure set to determine the highest value (h) in the set. The maximum value h is then used as a value that substantially represents the central aortic systolic pressure of the living body.

  In accordance with a second embodiment of the present invention, there is a method 100 for analyzing an arterial waveform data set to produce a corresponding central aortic pressure data set. Generally preceding this embodiment is that a medical practitioner obtains an arterial waveform representation of blood pressure in a living body by any technique known to those skilled in the art. This arterial waveform representation is then provided to the central processing station for determination of the corresponding central aortic pressure. After receiving the arterial waveform representation, the central processing station operates as follows.

  For each arterial waveform in the waveform data set, a corresponding central aortic pressure value a is determined and stored in the central aortic pressure data set according to the following process.

  The arterial waveform 102 being processed is divided into a set of representative blood pressure measurements (step 110). The set of blood pressure measurement values has a predetermined number of measurement values (n). In step 112, the predetermined number n is divided by the preset value (v) to determine an integer interval value (i).

Then, starting from the first blood pressure measurement bp [(f)], the following steps are repeated:
Blood pressure measurement values {bp [f], bp [f + 1], bp [f + 2], bp [f + 3],. . . , Bp [f + i−1]} (step 114) to obtain the value s;
The total value s is divided by the interval value i to obtain an average blood pressure value (a) (step 116).
The mean blood pressure value a is stored in a central aortic pressure set of multiple values (step 118).

  The above steps (steps 114 to 118) are repeated until f + i-1 is equal to n.

  Step 120 examines the analyzed central aortic pressure set of values to determine the highest value (h) in the set. The highest value h is then stored in the central aortic pressure data set as the central aortic systolic pressure value that matches the arterial waveform being processed.

  The above steps are then repeated until the corresponding central aortic pressure value has been calculated for each arterial waveform in the waveform data set.

  According to a third embodiment of the present invention, where similar numbers refer to similar steps, there is a method (not shown) for analyzing an arterial waveform data set to produce a corresponding central aortic pressure data set. This embodiment is based on experiments performed by the applicant, which have been found that the n value can take any value greater than 15.

In this embodiment, the v value is preferably 4 in order to determine an appropriate interval, but if the interval value is within a certain range, a fairly accurate aortic pressure value is obtained and the limits of that range are reached. Is determined as follows:
i _range = n / (t × v) ± (n / (t × 30))
In this embodiment, the variable t represents the duration (in seconds) of a single waveform.

  This embodiment will now be described in more detail in the context of the following example.

According to step 12, a set of blood pressure measurements from a living body representing an arterial waveform is created. The measurements are as follows (in order from left to right, top to bottom):
62.0 63.6 73.1 91.1 112.3 132.1 149.6 165.4 176.0 180.7
182.0 181.9 181.3 180.2 178.8 176.8 174.4 171.5 167.9 163.1
156.4 147.8 137.1 125.1 114.0 106.2 102.3 101.1 100.7 99.8
98.2 95.9 93.2 90.6 88.1 85.8 83.9 82.2 80.4 78.7
77.2 76.2 75.5 74.7 73.7 72.7 72.0 71.5 71.1 70.5
69.9 69.1 68.4 67.5 66.9 66.1 65.5 65.1 64.9 64.8
64.4 63.8 63.3 62.9 62.7 62.8 63.1 63.3 63.5 63.6
63.6 63.5 63.4 63.0 62.5 62.0

  The time taken to complete this waveform is 1.27 seconds.

This sets the n value to 76. If the v value is 4, the interval value range (i _range ) is determined as follows:
i _range = n / (t × v) ± (n / (t × 30)),
i _range = 76 / (1.27 × 4) ± (76 / (1.27 × 30)), thus
i _range = 14.96 ± (1.99)

Since the interval cannot be anything other than an integer value, the i _range value is limited to a range of 13-17. For the purposes of this example, an i value of 15 will be used.

In accordance with the requirements of steps 16-20, a multi-value central aortic pressure set is created having the following values:
{140.7 148.3 155.7 162.3 167.4 170.8
172.4 172.3 170.4 167.0 162.5 157.5
152.2 146.8 141.5 136.3 131.0 125.8
120.6 115.4 110.4 105.7 101.5 97.8
94.8 92.5 90.5 88.8 87.1 85.4
83.6 81.9 80.3 78.9 77.6 76.4
75.3 74.4 73.4 72.6 71.8 71.1
70.3 69.6 69.0 68.4 67.8 67.3
66.7 66.2 65.7 65.2 64.8 64.5
64.2 64.0 63.8 63.7 63.6 64.5
63.3 63.1}

  As can be seen, the multi-value central aortic pressure set has 62 elements, the value of which is equal to n−i + 1. From this set it is clear that the highest value (h) in the set is in fact the seventh data element (172.4). Accordingly, the central aortic systolic pressure of the living body is determined to be 172.4.

In a fourth most preferred embodiment of the invention, there is a method for determining central aortic pressure as described in the first embodiment of the invention. However, in this embodiment, the predetermined number n is determined according to the following equation:
n = sr × t
Where
sr = sample rate (hertz) of the measuring device used to record blood pressure measurements in set bp;
t = time (seconds) taken to complete one arterial waveform.

In this embodiment, the blood pressure measurement values in the set bp are measurement values obtained by the measurement device at each repetition of the sample rate. Furthermore, in this embodiment of the invention, the interval value is within a range whose limits are determined as follows:
i _range = sr / v ± (sr / 30)

  In this case, sr again represents the sample rate (hertz) of the measuring device used to record blood pressure measurements in the set bp. Furthermore, the v value is preferably 4. However, this equation is applicable only when the sr value exceeds 30.

Using the same blood pressure measurement set as described above, but this time, in the situation where the set is a culmination of blood pressure values obtained by a sampling device having a sample rate (sr) of 60 measurements per second, i _{The range} value is calculated as follows:
i _range = sr / v ± (sr / 30)
i _range = 60/4 ± (60/30)
i _range = 15 ± 2

As a result, the i _range value is between 13 and 17. The remainder of the method can then proceed as described in the first embodiment above.

  It should be understood by those skilled in the art that the above invention is not limited to the embodiments described herein. Specifically, the following modifications and improvements can be implemented without departing from the scope of the present invention.

    A set of blood pressure measurements can be obtained from a device that is also adapted to perform the method of the present invention. Alternatively, the set of blood pressure measurements can be obtained from a separate device and communicated to other devices adapted to perform the method of the present invention.

    The second embodiment of the present invention can be modified so that the waveform data set does not include a waveform, but instead the waveform data set data can include a set of data representing such a waveform. In this method, the process of step 110 can be omitted.

    The waveform data set can be provided to the entity performing the method along with the duration of each waveform in the data set. Alternatively, the entity implementing the method can, through alternative means (such as by receiving a graph with a fixed time value for a given length of the x-axis and approximating the duration of the waveform based on this time / distance relationship, etc. Alternatively, the duration of each waveform can be determined independently, such as by deriving the duration from other complex values, such as the sample rate used to create a set of blood pressure measurements.

    In order to best represent the arterial waveform, the blood pressure values forming the set bp should be uniformly distributed along the arterial waveform.

  It should be further understood by those skilled in the art that the features described above can be combined to form still other embodiments of the invention if not mutually exclusive.

Claims (30)

A method of obtaining central aortic systolic pressure,
a) creating a set representing an arterial waveform having a predetermined number of blood pressure measurements;
b) determining an integer interval value;
c) averaging a series of continuous blood pressure measurement readings in the set equal to the integer interval value starting from the f th blood pressure measurement in the set;
d) storing the averaged value in a central aortic systolic pressure set;
e) setting the central aortic systolic pressure as the highest value in the central aortic pressure set;
Step c. And d. Starts with a value of 1 and repeats by incrementing the value of f by 1 each time until the value of f plus the integer interval value is equal to the predetermined number of blood pressure measurements in the set. To obtain central aortic systolic pressure.   The method of obtaining central aortic systolic pressure according to claim 1, wherein the set of blood pressure measurements approximately matches a uniform distribution of values from the arterial waveform. Further comprising determining a duration of the arterial waveform, wherein the predetermined number of blood pressure measurements is determined according to the following equation:
Predetermined number = sr × t
Where
sr = sample rate (Hz) of the measuring device used to record the blood pressure measurements in the set,
The method of obtaining central aortic systolic pressure according to claim 2, wherein t = the duration of the arterial waveform.   The method of obtaining central aortic systolic pressure according to claim 3, wherein the integer interval value is a division of the sample rate.   The method of obtaining central aortic systolic pressure according to claim 4, wherein the integer interval value is the sample rate divided by four.   The method of obtaining central aortic systolic pressure according to claim 1 or 2, wherein the integer interval value is the predetermined number of divisions. The integer interval value is within a range whose boundaries are determined as follows:
i _range = n / (t × v) ± (n / (t × 30))
Where
n is the predetermined number of blood pressure measurements in the set;
t is the duration (in seconds) of the waveform;
The method of obtaining central aortic systolic pressure according to claim 6, wherein v is a predetermined division value.   The method of obtaining central aortic systolic pressure according to claim 7, wherein v = 4.   The method of obtaining central aortic systolic pressure according to claim 1 or 2, wherein the integer interval value is equal to 60 divided by a predetermined division value.   The method of obtaining central aortic systolic pressure according to claim 9, wherein the integer interval value is 15.   The method for obtaining central aortic systolic pressure according to any one of the preceding claims, wherein the predetermined number of blood pressure measurements in the set is 15 or more.   The method of obtaining central aortic systolic pressure according to claim 11, wherein the predetermined number of blood pressure measurements in the set is at least 30. A method for obtaining arterial waveform data to obtain a central aortic systolic pressure value,
a) receiving an arterial waveform data set;
b) dividing each arterial waveform in the arterial waveform data set into a representative set of blood pressure measurements having a predetermined number;
c) determining an integer interval value for the set being processed;
d) averaging a series of continuous blood pressure measurement readings in the set equal to the integer interval value starting from the f th blood pressure measurement in the set;
e) storing the averaged value in a central aortic systolic pressure set;
f) storing the highest value in the central aortic pressure set in the central aortic systolic pressure value set at a position corresponding to the position occupied by the processed arterial waveform in the arterial waveform data set; Including
Step b. ~ F. Is repeated for each arterial waveform in the arterial waveform data set, and for each such iteration, step d. And e. Furthermore, the value of f is incremented by 1 each time until the value of f starts at 1 and the value of f plus the integer interval value is equal to the predetermined number of blood pressure measurements in the set being processed. A method in which arterial waveform data is analyzed to obtain a central aortic systolic pressure value that is repeatedly incremented. A method for obtaining arterial waveform data to obtain a central aortic systolic pressure value,
a) receiving an arterial waveform data set, wherein each arterial waveform in the data set includes a representative set of blood pressure measurements having a predetermined number;
b) determining an integer interval value for the set being processed;
c) averaging a series of continuous blood pressure measurement readings in the set equal to the integer interval value starting from the f th blood pressure measurement in the set;
d) storing the averaged value in a central aortic systolic pressure set;
e) storing the highest value in the central aortic pressure set in the central aortic systolic pressure value set at a position corresponding to the position occupied by the processed arterial waveform in the arterial waveform data set; Including
Step b. ~ E. Is repeated for each arterial waveform in the arterial waveform data set, and for each such iteration, step c. And d. Furthermore, the value of f is incremented by 1 each time until the value of f starts at 1 and the value of f plus the integer interval value is equal to the predetermined number of blood pressure measurements in the set being processed. A method in which arterial waveform data is analyzed to obtain a central aortic systolic pressure value that is repeatedly incremented.   15. The arterial waveform of claim 14, wherein the predetermined number of blood pressure measurements for at least one arterial waveform in the data set is different from the predetermined number of blood pressure measurements for other arterial waveforms in the data set. A method for obtaining central aortic systolic pressure values by analyzing data.   16. The central aortic systolic pressure value by analyzing arterial waveform data according to any one of claims 13-15, wherein the set of blood pressure measurements approximately matches a uniform distribution of values from the arterial waveform. How to get. Further comprising determining a duration of the arterial waveform, wherein the predetermined number of blood pressure measurements is determined according to the following equation:
Predetermined number = sr × t
Where
sr = sample rate (Hz) of the measuring device used to record the blood pressure measurements in the set,
17. The method of analyzing arterial waveform data to obtain a central aortic systolic pressure value according to claim 16, wherein t = the duration of the arterial waveform.   18. The method of analyzing arterial waveform data to obtain a central aortic systolic pressure value according to any one of claims 13 to 17, wherein the integer interval value is a division of the sample rate.   The method of analyzing arterial waveform data to obtain a central aortic systolic pressure value according to claim 18, wherein the integer interval value is the sample rate divided by four.   The method of obtaining central aortic systolic pressure value by analyzing arterial waveform data according to any one of claims 13 to 17, wherein the integer interval value is the predetermined number of divisions. The integer interval value is within a range whose boundaries are determined as follows:
i _range = n / (t × v) ± (n / (t × 30))
Where
n is the predetermined number of blood pressure measurements in the set;
t is the duration (in seconds) of the waveform;
21. The method according to claim 20, wherein v is a predetermined division value and the arterial waveform data is analyzed to obtain a central aortic systolic pressure value.   The method for obtaining a central aortic systolic pressure value according to claim 21, wherein v = 4.   15. A method for obtaining a central aortic systolic pressure value according to claim 13 or 14, wherein the integer interval value is equal to 60 divided by a predetermined division value.   24. The method for obtaining a central aortic systolic pressure value according to claim 23, wherein the integer interval value is 15.   25. The method of obtaining central aortic systolic pressure value by analyzing arterial waveform data according to any one of claims 13 to 24, wherein the predetermined number of blood pressure measurements in the set is 15 or more.   26. The method of analyzing arterial waveform data to obtain a central aortic systolic pressure value according to claim 25, wherein the predetermined number of blood pressure measurements in the set is at least 30. An arterial waveform measuring device;
A system for obtaining central aortic systolic pressure comprising a processing unit,
The arterial waveform measurement device acquires blood pressure measurements at predetermined intervals until at least one arterial waveform is represented by the acquired set of blood pressure measurements, and then the blood pressure measurement value representing one arterial waveform A set is communicated to the processing unit;
a) determine an integer interval value;
b) averaging a series of continuous blood pressure measurement readings in the set equal to the integer interval value starting from the f th blood pressure measurement in the set;
c) storing said averaged value in a central aortic systolic pressure set;
d) setting the central aortic systolic pressure as the highest value in the central aortic pressure set;
Step b. And c. Is repeated starting with a value of f and incrementing the value of f by 1 each time until the value of f plus the integer interval value equals the number of blood pressure measurements in the set. A system for obtaining central aortic systolic pressure. A computer readable medium having software recorded thereon for obtaining central aortic systolic pressure, the software comprising:
Setting means for creating a set representing an arterial waveform having a predetermined number of blood pressure measurements;
Means for determining an integer interval value;
An averaging means for averaging a series of consecutive blood pressure measurement readings in the set equal to the integer interval value starting from the fth blood pressure measurement in the set;
Storage means for storing the averaged value in a central aortic systolic pressure set;
A result means for setting the central aortic systolic pressure as the highest value in the central aortic pressure set;
The functions of the averaging means and the storage means start with a value of f of 1, and add the integer interval value to the value of f until the value of f is equal to the predetermined number of blood pressure measurements in the set A computer readable medium that is repeated with the value incremented by one each time. A computer readable medium having software recorded thereon for analyzing arterial waveform data to obtain a central aortic systolic pressure value, the software comprising:
A communication means for receiving the arterial waveform data set;
Set means for dividing each arterial waveform in the arterial waveform data set into a representative set of blood pressure measurements having a predetermined number;
An interval means for determining an integer interval value for the set being processed;
Averaging means for averaging a series of consecutive blood pressure measurement readings in the set equal to the integer interval value starting from the f th blood pressure measurement in the set;
First storage means for storing said averaged value in a central aortic systolic pressure set;
Second storage means for storing the highest value in the central aortic pressure set in the central aortic systolic pressure value set at a position corresponding to the position occupied by the processed arterial waveform in the arterial waveform data set; Including,
The functions of the setting means, the spacing means, the averaging means, the first storage means, and the second storage means are repeated for each arterial waveform in the arterial waveform data set, The function of the averaging means and the first storage means is further provided with the predetermined value of the blood pressure measurement value in the set in which the value of f starts with 1 and the value obtained by adding the integer interval value to the value of f is processed. A computer readable medium that is repeated with the value of f incremented by 1 each time until equal to the number. A computer readable medium having software recorded thereon for analyzing arterial waveform data to obtain a central aortic systolic pressure value, the software comprising:
a) communication means for receiving an arterial waveform data set, the communication means comprising a representative set of blood pressure measurements, each arterial waveform in the data set having a predetermined number;
b) an interval means for determining an integer interval value for the set being processed;
c) an averaging means for averaging a series of continuous blood pressure measurement readings in the set equal to the integer interval value starting from the f th blood pressure measurement in the set;
d) first storage means for storing said averaged value in a central aortic systolic pressure set;
e) Second storage for storing the highest value in the central aortic pressure set in the central aortic systolic pressure value set at a position corresponding to the position occupied by the processed arterial waveform in the arterial waveform data set. Means, and
The functions of the spacing means, the averaging means, the first storage means, and the second storage means are repeated for each arterial waveform in the arterial waveform data set, and for each such repetition, the averaging means and the The function of the first storage means is further equal to the predetermined number of blood pressure measurements in the set in which the value of f starts at 1, and the value of f plus the integer interval value is processed. A computer readable medium that is repeated by incrementing the value of f by 1 each time.

Images