TWI441618B - A method of deriving central aortic systolic pressure and a method of analysing arterial waveform data to derive central aortic systolic pressure values - Google Patents

Description

Method for deriving central aortic systolic pressure and method for analyzing arterial waveform data to derive central aortic systolic pressure values Field of invention

The present invention relates to a method of deriving a central aortic systolic pressure and a method of analyzing arterial waveform data to derive a central aortic systolic pressure value. According to a first method of the invention, the invention is particularly suitable for deriving a central aortic systolic pressure from an arterial waveform. However, in accordance with the second method of the present invention, the present invention is suitable for analyzing a collection of arterial waveform data to derive a corresponding central aortic systolic data set.

Background of the invention

The discussion of the background of the invention below is intended to assist in understanding the invention. However, it must be understood that the discussion is not an endorsement or admission that any of the information cited herein is deemed to be part of the published, known or common knowledge at the date of the priority application of the case.

Heart disease is a serious health problem in developed countries. One indicator of potential heart disease is a change in the "normal" range of live blood pressure and regulations.

The blood pressure measurement method of the living body is to measure the blood pressure reading of the living body (both systolic blood pressure and heart pressure) using a pressure cuff. These values are generally used as a substitute for central arterial pressure values. Although this hypothesis has proven useful in predicting potential heart disease in the past, recent studies have indicated that the "normal" arm blood pressure values measured by this method may mask the abnormal central aortic systolic blood pressure values.

Atcor Medical Pty Ltd. of New South Wales, Australia has adopted a solution to this problem. Aite's solution uses a proprietary conversion formula to turn the arterial pressure waveform Change to the central aortic pressure waveform. However, this formula can only be used with the proprietary software sold by Atech, along with its SphygmoCor blood pressure inspection system. More importantly, the formula is based on cross-correlation values determined by testing for cross-representative patients, and thus errors may be introduced for patient central aortic introversion values that fall outside the range of the cross-representative samples.

Summary of invention

In the full text, terms such as "including" and "comprising" shall be interpreted as non-exclusive, in other words, "including but not limited to" unless stated to the contrary.

In the description of the embodiments of the present invention, the term "living body" refers to the body when the artery waveform is generated. The present invention is not considered to be limited to the calculation of the central aortic pressure value excluding the arterial waveform from a patient who died.

According to a first aspect of the invention, a method of deriving a central aortic systolic pressure comprises the steps of: a) forming a set of blood pressure measurements having a predetermined number, the set representing an arterial waveform; b) determining an integer interval Value: c) the fth blood pressure measurement starting from the set, averaging a series of consecutive blood pressure measurement readings equal to the integer interval value in the set; d) storing the average value in a central aortic heart a set of constricted pressures; and e) setting the central aortic systolic pressure to be the highest value in the central aortic pressure set, Here, the f values start at 1 and each step is incremented by 1 to repeat steps c. and d. until the f value plus the integer interval value is equal to the predetermined number of blood pressure measurements in the set.

The set of blood pressure measurements is substantially equal to the uniform distribution of values from the arterial waveform. In particular, the method preferably includes the step of determining the length of time of the arterial waveform. The waveform time length is then used to determine the predetermined number according to the following formula: a predetermined number = sr x t where sr = a sample rate for recording the blood pressure measurement at one of the set of measuring devices, in Hertz; and t = The length of time of the arterial waveform.

The integer interval value can be the divisor of the sample rate. Ideally, the integer interval value is the sample rate divided by four.

Additionally, the integer interval value can be a predetermined number of blood pressure measurements in the set of blood pressure measurements. Ideally, using this technique, integer interval values fall within the boundaries of the following measurements: i _range = n / (t × v) ± (n / (t × 30)) where n is the blood pressure measurement in the set The predetermined number of values; t is the length of time (in seconds) of the waveform; and v is the predetermined divisor value.

Preferably, but not necessarily when calculating the aforementioned range, the value of v is set to four.

In another alternative combination, the integer interval value is equal to 60 divided by a predetermined divisor value. In another alternative combination, the integer interval value is 15.

The predetermined number of blood pressure measurements in the set is equal to or greater than 15. Preferably, however, the predetermined number of blood pressure measurements in the set is at least 30.

In its optimal configuration, the predetermined number of blood pressure measurements in the set is at least 30 and the interval is 15.

According to a second aspect of the present invention, a method of analyzing an arterial waveform data to derive a central aortic systolic pressure value comprises the steps of: a. receiving an arterial waveform data set; b. receiving each artery in the arterial waveform data set The waveform is divided into a representative set having a predetermined number of blood pressure measurements; c. an integer interval value is determined for the set of accepted treatments; d. the fth blood pressure measurement starting from the set, the average one being listed a continuous blood pressure measurement reading equal to the integer interval value in the set; e. storing the average value in a central aortic systolic pressure set; and f. storing the highest value in the central aortic pressure set in a central aorta a set of systolic pressure values corresponding to one of positions occupied by the received arterial waveform in the set of arterial waveform data, where steps b. to steps are repeated for each arterial waveform in the set of arterial waveform data f., and for each such repetition, starting at 1 with an f value of 1 and incrementing by 1 each time, further repeating steps d. and e. until the f value plus the integer interval value is equal to the acceptance The predetermined number of blood pressure measurements in the set.

According to a third aspect of the present invention, a method of analyzing an arterial waveform data to derive a central aortic systolic pressure value comprises the steps of: a. receiving an arterial waveform data set, wherein each arterial waveform in the data set comprises a predetermined number of representative blood pressure measurements a set; b. determining an integer interval value for the set to be processed; c. a f-th blood pressure measurement starting from the set, averaging a series of consecutive blood pressure measurement readings in the set equal to the integer interval value; d. storing the average in a central aortic systolic pressure set; and e. storing the highest value in the central aortic pressure set in a central aortic systolic blood pressure value set, and the received arterial waveform Repeating step b. to step e. for each arterial waveform in the set of arterial waveform data, corresponding to one of the positions occupied by the set of arterial waveform data, and starting with f for each such repetition Step 1 and step d. are further repeated at 1 and incremented by 1 each time until the value of f plus the integer interval value is equal to the predetermined number of blood pressure measurements in the set undergoing processing.

The predetermined number of blood pressure measurements of at least one of the arterial waveforms in the data set is different from the predetermined number of blood pressure measurements of the other arterial waveforms in the data set.

In both the second and third phases of the present invention, the set of blood pressure measurements must be substantially equal to a uniform distribution of values from the arterial waveform.

Ideally, the method further comprises the step of determining the length of time of the arterial waveform. The length of time of the waveform can then be determined according to the following formula: the predetermined number = sr x t where sr = the sample rate used to record the blood pressure measurement at one of the set of measuring devices, in Hertz; and t = arterial The length of the waveform.

The integer interval value can be the divisor of the sample rate (sr). Ideally, however, the integer interval is the sample rate divided by four.

Additionally, the integer interval value can be a predetermined number of blood pressure measurements in the set of blood pressure measurements. Ideally, using this technique, integer interval values fall within the boundaries of the following measurements: i _range = n / (t × v) ± (n / (t × 30)) where n is the blood pressure measurement in the set The predetermined number of values; t is the length of time (in seconds) of the waveform; and v is the predetermined divisor value.

In the present formula, it is further preferred that the value of v is set to four.

In another alternative combination, the integer interval value is equal to 60 divided by a predetermined divisor value. In another alternative combination, the integer interval value is 15.

The predetermined number of blood pressure measurements in the set is equal to or greater than 15. A collection of 30 blood pressure measurements is preferred.

According to a fourth aspect of the present invention, a system for deriving a central aortic systolic pressure comprises: an arterial waveform measuring device; and a processing unit, wherein the arterial waveform measuring device performs blood pressure measurement at predetermined time intervals until At least one arterial waveform is represented by the measured set of blood pressure measurements, and then the set of blood pressure measurements representing an arterial waveform is communicated to the processing unit, the processing unit having: a) determining an integer interval value: b) the fth blood pressure measurement starting from the set, averaging a series of consecutive blood pressure measurement readings equal to the integer interval value in the set; c) storing the average value in a central aortic systolic pressure a set; and d) setting the central aortic systolic pressure to be the highest value in the central aortic pressure set, where the f value starts at 1 and each time increments by 1 repeats steps c. and d. until the f value is added The integer interval value is equal to the number of blood pressure measurements in the set.

In accordance with an additional aspect of the present invention, there is a computer readable medium having a soft body thereon for performing the methods of the first, second and third aspects of the present invention.

Simple illustration

The invention will now be described with reference to the accompanying drawings, in which: FIG. 1 is a flow chart showing a method for determining the central aortic pressure of a living body in accordance with a first embodiment of the present invention.

2 is a flow chart of a method of analyzing a collection of arterial waveforms to produce a corresponding collection of central arterial pressure data in accordance with a second embodiment of the present invention.

Figure 3 is an illustrative arterial waveform that can be processed by any of the embodiments of the invention to obtain a central aortic compression value.

Detailed description of the preferred embodiment

Specific embodiments of the present invention will now be described with reference to the drawings. The terminology used herein is for the purpose of illustration and description, In addition, unless otherwise defined, all technical terms used herein have the ordinary skill of the art to which the invention belongs. The same definition of solution.

In accordance with a first embodiment of the present invention, a method 10 of measuring central aortic pressure is provided. Method 10 is illustrated in the flow chart of Figure 1.

As shown in Fig. 1, the method 10 begins by forming a set of blood pressure measurements derived from a living body representative of an arterial waveform (step 12). The set of blood pressure measurements has a predetermined number of measurements (n). In step 14, the predetermined number n is divided by a preset value (v) to determine an integer interval value (i). In this way, the integer interval value (i) can accept an absolute value or an approximation mathematical function operation.

Then repeat the following steps, starting with the first blood pressure measurement bp[(f)]: blood pressure measurement {bp[f], bp[f+1], bp[f+2], bp[f+3],..., bp[f+i -1]} is summed (step 16) to form an s value; the total value s is divided by the integer value i to form an average blood pressure value (a) (step 18).

The average blood pressure value a is stored in a central aortic pressure value set (step 20).

The foregoing steps (steps 16 to 20) are repeated until f+i-1 is equal to n.

Step 22 observes the set of central aortic compressions analyzed to determine the highest value (h) in the set. The highest value h is then used as a substantially representative value for the central aortic systolic pressure of the living body.

In accordance with a second embodiment of the present invention, a method 100 of analyzing a collection of arterial waveform data to produce a corresponding collection of central arterial pressure data is provided. In this embodiment, a representative arterial waveform of living blood pressure is generally obtained by a medical professional according to any technique known to those skilled in the art. This representative arterial waveform is then presented to the central processing station for the corresponding central aorta Determination of pressure. After receiving the waveform of the arterial waveform, the central processing station operates as follows: the corresponding central aortic pressure value a is determined for each of the arterial waveforms in the waveform data set and stored in the central aortic pressure data set according to the following procedure.

The processed arterial waveform 102 is equally divided into a representative blood pressure measurement set (step 110). The set of blood pressure measurements has a predetermined number of measurements (n). At step 112, the predetermined number n is divided by a predetermined value (v) to determine an integer interval value (i).

Then repeat the following steps, starting with the first blood pressure measurement bp[(f)]: blood pressure measurement values {bp[f], bp[f+1], bp[f+2], bp[f+3],. .., bp[f+i-1]} is summed (step 114) to form an s value; the total value s is divided by the integer value i to form an average blood pressure value (a) (step 116).

The average blood pressure value is stored in a central aortic pressure value set (step 118).

The foregoing steps (steps 114 to 118) are repeated until f+i-1 is equal to n.

Step 120 observes the set of central aortic pressures analyzed to determine the highest value (h) in the set. The highest value h is then stored in the central aortic pressure data set as a central aortic systolic pressure value corresponding to the waveform of the artery being treated.

The foregoing steps are then repeated until the corresponding central aortic pressure value has been determined for each of the arterial waveforms in the waveform data set.

According to a third embodiment of the present invention, similar symbolic representations are used herein. A similar procedure is a method of analyzing a collection of arterial waveform data to produce a corresponding collection of central aortic pressure data (not shown). This example is based on experiments conducted by the applicant and found that the value of n can be any value greater than 15.

In the present embodiment, although the v value is preferably 4 to determine the appropriate interval, a substantially correct aortic pressure value can be obtained, where the interval value is a range, and the limit of the range is determined as follows: i _range = n / (t×v)±(n/(t×30))

In this embodiment, the variable t represents the length of time (in seconds) of a single waveform.

Further details of this embodiment will be described in the context of the following examples: According to step 12, a representative set of blood pressure measurements from the waveform of the artery of the living body is formed. These measurements are as follows (sequence from left to right, top to bottom): 62.0 63.6 73.1 91.1 112.3 132.1 149.6 165.4 176.0 180.7 182.0 181.9 181.3 180.2 178.8 176.8 174.4 171.5 167.9 163.1 156.4 147.8 137.1 125.1 114.0 106.2 102.3 101.1 100.7 99.8 98.2 95.9 93.2 90.6 88.1 85.8 83.9 82.2 80.4 78.7 77.2 76.2 75.5 74.7 73.7 72.7 72.0 71.5 71.1 70.5 69.9 69.1 68.4 67.5 66.9 66.1 65.5 65.1 64.9 64.8 64.4 63.8 63.3 62.9 62.7 62.8 63.1 63.3 63.5 63.6 63.6 63.5 63.4 63.0 62.5 62.0

The length of time required to complete this waveform is 1.27 seconds.

The n value is set to 76 in this way. Using a v value of 4, the range of interval values (i _range ) is determined as follows: i _range = n / (t × v) ± (n / (t × 30)), so i _range = 76 / (1.27 × 4) ± ( 76/(1.27×30)), so the i _range = 14.96±(1.99)

Since the interval cannot be any value other than the integer value, the i _range value is limited to the range of 13 to 17. For the purposes of this example, an i value of 15 shall be used.

Following the requirements of steps 16 through 20, the central aortic pressure value set has the following values: {140.7 148.3 155.7 162.3 167.4 170.8 172.4 172.3 170.4 167.0 162.5 157.5 152.2 146.8 141.5 136.3 131.0 125.8 120.6 115.4 110.4 105.7 101.5 97.8 94.8 92.5 90.5 88.8 87.1 85.4 83.6 81.9 80.3 78.9 77.6 76.4 75.3 74.4 73.4 72.6 71.8 71.1 70.3 69.6 69.0 68.4 67.8 67.3 66.7 66.2 65.7 65.2 64.8 64.5 64.2 64.0 63.8 63.7 63.6 64.5 63.3 63.1

It can be seen that the central aortic pressure value set has 62 elements, and its value is equal to n-i+1. From this set, it is clear that the highest value (h) in the set is tied to the seventh data element (172.4). Thus, the central aortic systolic pressure of the living body was determined to be 172.4.

In a fourth and preferred embodiment of the invention, a method of determining central aortic pressure as in the first embodiment of the invention. However, in the present embodiment, the predetermined number n is determined according to the following formula: n = sr × t Here Sr = sample rate (in Hertz) of the measuring device for recording the blood pressure measurement bp of the set; and t = time taken to complete an arterial waveform (in seconds).

In the present embodiment, the blood pressure measurement value bp in the collection is the measurement value obtained by the measurement device at each repeated sample rate. Further, in the present embodiment of the present invention, the interval value is expressed by a range, and the limit of the range is determined as follows: i _range = sr / v ± (sr / 30)

In this case, sr again represents the sample rate (in Hertz) of the measuring device for the blood pressure measurement value bp recorded in the set. Further, the value of v is preferably 4. However, this formula only applies to sr values exceeding 30.

The same set of blood pressure measurements as listed above is used, but this time the set is the apex of the blood pressure value obtained by the sampling device having the sample rate (sr) of 60 measurements per second, and the i _range value is calculated as follows: i _range = sr / v ± (sr / 30) i _range = 60 / 4 ± (60 / 30) i _range = 15 ± 2

Thus, a _range value of 13 to 17 is obtained. The remainder of the method is then carried out as in the first embodiment described above.

It will be appreciated by those skilled in the art that the foregoing invention is not limited to the specific embodiments described. In particular, the following modifications and improvements may be made without departing from the scope of the invention: A collection of blood pressure measurements can be obtained from a device that is also designed to perform the methods of the present invention. In addition, the blood pressure measurement set is available From a separate device, communication to an additional device designed to fit one of the methods of the present invention.

. The second embodiment of the present invention can be modified so that the set of waveform data does not contain waveforms. Instead, the data of the set of waveform data may contain a collection of data representative of such waveforms. In this way, the processing of step 110 can be deleted.

. The set of waveform data can be supplied to the entity performing the method along with the length of time of each waveform in the set of data. Additionally, the entity performing the method can determine the length of time of each waveform independently of other means (such as by receiving a line graph having a fixed time value for a predetermined x-axis length and estimating the time based on the time/distance relationship) The length of time of the waveform; or by deriving the length of time from other composite values, such as the sample rate used to generate a set of blood pressure measurements.

. The most representative arterial waveform, the blood pressure value bp forming the set must be evenly distributed along the arterial waveform.

Those skilled in the art will further appreciate that the foregoing features are not mutually exclusive and may be combined to form additional embodiments of the present invention.

10‧‧‧ method for measuring central aortic pressure

12-22‧‧‧ Method steps

100‧‧‧ method for analyzing a collection of arterial waveform data to generate a corresponding central aortic pressure data set

110-120‧‧‧ Method steps

Fig. 1 is a flow chart showing a method of measuring a central aortic pressure of a living body according to a first embodiment of the present invention.

2 is a flow chart of a method of analyzing a collection of arterial waveforms to produce a corresponding collection of central arterial pressure data in accordance with a second embodiment of the present invention.

Figure 3 is an illustrative arterial waveform that can be processed by any of the embodiments of the invention to obtain a central aortic compression value.

10‧‧‧ method

12-22‧‧‧ Method steps

Claims (30)

A method of deriving a central aortic systolic pressure comprising the steps of: a. forming a set of blood pressure measurements having a predetermined number, the set representing an arterial waveform; b. determining an integer interval value; c. starting at the set The fth blood pressure measurement value in the set, in the set equal to one of the integer interval values, the serial continuous blood pressure measurement read value; d. storing the average value in a central aortic systolic pressure set; and e. setting the The central aortic systolic pressure is the highest value in the central aortic systolic pressure set, where the f value starts at 1 and each time increments by 1 repeats steps c. and d. until the f value plus the integer interval value equals the The predetermined number of blood pressure measurements in the collection. The method of deriving a central aortic systolic pressure according to claim 1 of the patent scope, wherein the blood pressure measurement set is substantially equal to one of the values obtained from the arterial waveform. The method of deriving a central aortic systolic pressure according to claim 2, further comprising the step of determining the length of time of the arterial waveform, and wherein the predetermined number of blood pressure measurements is determined according to the following formula: predetermined number = sr ×t where sr= is used to record the sample rate of the blood pressure measurement at one of the set of measurement devices in Hertz (Hz); and t = the length of time of the arterial waveform. The method of deriving a central aortic systolic pressure according to item 3 of the patent application, wherein the integer interval value is a divisor of the sample rate. For example, in the method of claim 4, the method of deriving the central aortic systolic pressure, where the integer interval value is the sample rate divided by 4. The method of deriving a central aortic systolic pressure according to claim 1 or 2, wherein the integer interval value is a divisor of the predetermined number. For example, in the method of claim 6, the method of deriving the central aortic systolic pressure, where the integer interval value falls within the boundary of the following determination: i _range = n / (t × v) ± (n / (t ×30)) where n is the predetermined number of blood pressure measurements in the set; t is the length of time (in seconds) of the waveform; and v is the predetermined divisor value. For example, the method of deriving central aortic systolic pressure according to item 7 of the patent application scope, where v=4. The method of deriving a central aortic systolic pressure according to claim 1 or 2, wherein the integer interval value is equal to 60 divided by a predetermined divisor value. For example, in the method of claim 9, the method of deriving the central aortic systolic pressure, wherein the integer interval value is 15. A method of deriving a central aortic systolic pressure according to any one of claims 1 to 5, wherein the predetermined number of blood pressure measurements in the set is equal to or greater than 15. The method of deriving a central aortic systolic pressure according to claim 11 of the patent scope, wherein the predetermined number of blood pressure measurements in the collection is at least 30. A method of analyzing arterial waveform data to derive a central aortic systolic pressure value, comprising the steps of: a) receiving an arterial waveform data set; b) dividing each arterial waveform in the arterial waveform data set into a predetermined number of blood pressures a representative set of measured values; c) determining an integer interval value for the set of accepted treatments; d) starting from the fth blood pressure measurement in the set, averaging one of the integer interval values in the set Blood pressure measurement readings; e) storing the average value in a central aortic systolic pressure set; and f) storing the highest value in the central aortic systolic pressure set in a central aortic systolic pressure value set, Repetitively repeating step b. to step f. for each arterial waveform in the set of arterial waveform data, and for each position corresponding to the position occupied by the processed arterial waveform in the set of arterial waveform data, and for each time Such repetition, starting at 1 with an f value and incrementing by 1 each, further repeats steps d. and e. until the f value plus the integer interval value is equal to the blood pressure measurement in the set of treatments accepted. The predetermined number. A method of analyzing arterial waveform data to derive a central aortic systolic pressure value, comprising the steps of: a) receiving an arterial waveform data set, wherein each arterial waveform in the data set comprises a predetermined number of representative blood pressure measurements a set; b) determining an integer interval value for the set of processes to be processed; c) starting from the fth blood pressure measurement in the set, averaging one of the set of continuous interval blood pressure measurement readings in the set; d) storing the average value in a central aortic systolic pressure set; And e) storing the highest value of the central aortic systolic pressure set in a central aortic systolic blood pressure value set corresponding to the position occupied by the processed arterial waveform in the arterial waveform data set a position where the steps b. to e. are repeated for each arterial waveform in the set of arterial waveform data, and for each such repetition, the f value starts at 1 and increments by 1 each, further repeating step c. Step d. Up to the value of f plus the integer interval value equal to the predetermined number of blood pressure measurements in the set of treatments. For example, in the method of analyzing the arterial waveform data of claim 14 to derive the central aortic systolic pressure value, the predetermined number of blood pressure measurement values of at least one arterial waveform in the data set is different from the data set. The predetermined number of blood pressure measurements of other arterial waveforms. The method of analyzing arterial waveform data according to any one of claims 13 to 15 to derive a central aortic systolic pressure value, wherein the blood pressure measurement set is substantially equal to one of the values obtained from the arterial waveform. Evenly distributed. The method for analyzing the arterial waveform data to derive the central aortic systolic pressure value according to claim 16 of the patent application, further comprising the step of determining the length of time of the arterial waveform, and wherein the predetermined number of blood pressure measurements is based on the following formula determination: The predetermined number = sr x t where sr = the sample rate of the measuring device used to record the blood pressure measurement in one of the sets, in Hertz; and t = the length of time of the arterial waveform. The method of analyzing arterial waveform data according to any one of claims 13 to 15 to derive a central aortic systolic pressure value, where the integer interval value is a divisor of the sample rate. For example, the method of analyzing the arterial waveform data of claim 18 to derive the central aortic systolic pressure value, where the integer interval value is the sample rate divided by 4. The method of analyzing arterial waveform data as disclosed in any one of claims 13 to 15 to derive a central aortic systolic pressure value, wherein the integer interval value is one of the predetermined number divisors. For example, the method of analyzing the arterial waveform data of claim 20 to derive the central aortic systolic pressure value, where the integer interval value falls within the boundary of the following determination: i _range = n / (t × v) ±(n/(t×30)) where n is the predetermined number of blood pressure measurements in the set; t is the length of time (in seconds) of the waveform; and v is the predetermined divisor value. For example, the method of analyzing the arterial waveform data of claim 21 to derive the central aortic systolic pressure value, here v=4. For example, the method of analyzing arterial waveform data of claim 13 or 14 to derive a central aortic systolic pressure value, where the integer interval value is equal to 60 divided by a predetermined divisor value. For example, the method of analyzing the arterial waveform data of claim 23 to derive the central aortic systolic pressure value, where the integer interval value is 15. The method of analyzing arterial waveform data according to any one of claims 13 to 15 to derive a central aortic systolic pressure value, wherein the predetermined number of blood pressure measurement values in the set is equal to or greater than 15. For example, the method of analyzing arterial waveform data of claim 25 to derive the central aortic systolic pressure value, wherein the predetermined number of blood pressure measurements in the set is at least 30. A system for deriving a central aortic systolic pressure, comprising: an arterial waveform measuring device; and a processing unit, wherein the arterial waveform measuring device performs blood pressure measurement at predetermined time intervals until at least one arterial waveform is measured a set of blood pressure measurements, and then the set of blood pressure measurements representing an arterial waveform is communicated to the processing unit, the processing unit: a) determining an integer interval value; b) starting from the fth of the set a blood pressure measurement, averaging one of the integer interval values in the set, a series of consecutive blood pressure measurement readings; c) storing the average value in a central aortic systolic pressure set; and d) setting the central aortic systole Pressure for the central aortic heart The highest value in the set of contractions, where the f value starts at 1 and each step is incremented by 1 to repeat steps b. and c. until the f value plus the integer interval value is equal to the number of blood pressure measurements in the set. A computer readable medium having a soft body recorded thereon for deriving a central aortic systolic pressure, the software comprising: setting means for forming a set of blood pressure measurements having a predetermined number, the set representing an arterial waveform; a determining component for determining an integer interval value; an averaging component for the fth blood pressure measurement starting from the set, averaging one of the set of continuous interval blood pressure measurement readings in the set; the storage component And storing the average value in a central aortic systolic pressure set; and a result member for setting the central aortic systolic pressure to be the highest value in the central aortic systolic pressure set, where the average The function of the member and the storage member begins with a f value of 1 and increments by 1 each time until the f value plus the integer interval value is equal to the predetermined number of blood pressure measurements in the set. A computer readable medium having a software recorded thereon for analyzing an arterial waveform data to derive a central aortic systolic pressure value, the software comprising: a communication member for receiving an arterial waveform data set; and a setting member for Dividing each arterial waveform in the set of arterial waveform data into a representative set having a predetermined number of blood pressure measurements; An interval component for determining an integer interval value for the set of accepted processes; an averaging component for the fth blood pressure measurement starting from the set, averaging one of the set of continuous interval blood pressure measurements equal to the integer interval value Reading a value; a first storage member for storing the average value in a central aortic systolic pressure set; and a second storage member for storing the highest value of the central aortic systolic pressure set in a central master a set of arterial systolic pressure values at a position corresponding to a position occupied by the processed arterial waveform in the set of arterial waveform data, where the setting member, the interval member, the averaging member, the first storage member, and the The function of the two storage members is repeated for each of the arterial waveforms in the set of arterial waveform data, and for each such repetition, the f-value starts at 1 and increments by one each time, and the average member and the first storage member are further repeated. The function up to the value of f plus the integer interval value is equal to the predetermined number of blood pressure measurements in the set of treatments. A computer readable medium having a software recorded thereon for analyzing an arterial waveform data to derive a central aortic systolic pressure value, the software comprising: a) a communication member for receiving an arterial waveform data set, where Each arterial waveform in the data set includes a predetermined number of representative blood pressure measurement sets; b) an interval component for determining an integer interval value for the set of accepted processes; c) an averaging component for the fth blood pressure measurement starting from the set, averaging one of the set of continuous interval blood pressure measurement readings equal to the integer interval value; d) a first storage member for storing the Mean in a central aortic systolic pressure set; and e) a second storage member for storing the highest value in the central aortic systolic pressure set in a central aortic systolic pressure value set, The position of the processed artery waveform corresponding to the position occupied by the set of arterial waveform data, wherein the function of the interval member, the average member, the first storage member and the second storage member is in the set of arterial waveform data Each arterial waveform is repeated, and for each such repetition, the f value starts at 1 and increments by 1 each time, and the functions of the averaging member and the first storage member are further repeated until the f value plus the integer interval value is equal to the accepted treatment. The predetermined number of blood pressure measurements in the collection.