JP2010528039A5 - - Google Patents
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- Publication number
- JP2010528039A5 JP2010528039A5 JP2010509527A JP2010509527A JP2010528039A5 JP 2010528039 A5 JP2010528039 A5 JP 2010528039A5 JP 2010509527 A JP2010509527 A JP 2010509527A JP 2010509527 A JP2010509527 A JP 2010509527A JP 2010528039 A5 JP2010528039 A5 JP 2010528039A5
- Authority
- JP
- Japan
- Prior art keywords
- hyaluronic acid
- particles
- composition
- encapsulated
- coated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002245 particle Substances 0.000 claims 18
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 17
- 229920002674 hyaluronan Polymers 0.000 claims 17
- 229960003160 hyaluronic acid Drugs 0.000 claims 17
- 239000000203 mixture Substances 0.000 claims 14
- 239000011248 coating agent Substances 0.000 claims 5
- 238000000576 coating method Methods 0.000 claims 5
- 239000000945 filler Substances 0.000 claims 4
- 150000004676 glycans Chemical class 0.000 claims 4
- 229920001282 polysaccharide Polymers 0.000 claims 4
- 239000005017 polysaccharide Substances 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 3
- 230000008961 swelling Effects 0.000 claims 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 2
- 230000002500 effect on skin Effects 0.000 claims 2
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 1
- 102000009027 Albumins Human genes 0.000 claims 1
- 108010088751 Albumins Proteins 0.000 claims 1
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Natural products OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims 1
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 1
- 229940072056 alginate Drugs 0.000 claims 1
- 229920000615 alginic acid Polymers 0.000 claims 1
- 235000010443 alginic acid Nutrition 0.000 claims 1
- 230000003416 augmentation Effects 0.000 claims 1
- 229920002988 biodegradable polymer Polymers 0.000 claims 1
- 239000004621 biodegradable polymer Substances 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 229920006037 cross link polymer Polymers 0.000 claims 1
- 229920006237 degradable polymer Polymers 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 claims 1
- 238000002513 implantation Methods 0.000 claims 1
- 239000004005 microsphere Substances 0.000 claims 1
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 1
- 210000004872 soft tissue Anatomy 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 238000010254 subcutaneous injection Methods 0.000 claims 1
- 239000007929 subcutaneous injection Substances 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93965907P | 2007-05-23 | 2007-05-23 | |
| PCT/US2008/064378 WO2008147817A2 (en) | 2007-05-23 | 2008-05-21 | Coated hyaluronic acid particles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010528039A JP2010528039A (ja) | 2010-08-19 |
| JP2010528039A5 true JP2010528039A5 (https=) | 2011-07-07 |
Family
ID=39645603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010509527A Pending JP2010528039A (ja) | 2007-05-23 | 2008-05-21 | 被覆されたヒアルロン酸粒子 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20090022808A1 (https=) |
| EP (1) | EP2162158A2 (https=) |
| JP (1) | JP2010528039A (https=) |
| AU (1) | AU2008256864A1 (https=) |
| BR (1) | BRPI0811777A2 (https=) |
| CA (1) | CA2687983A1 (https=) |
| WO (1) | WO2008147817A2 (https=) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2861734B1 (fr) | 2003-04-10 | 2006-04-14 | Corneal Ind | Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus |
| US20090148527A1 (en) * | 2007-12-07 | 2009-06-11 | Robinson Michael R | Intraocular formulation |
| US20060073208A1 (en) * | 2004-10-01 | 2006-04-06 | Allergan, Inc. | Cosmetic neurotoxin compositions and methods |
| WO2008147867A2 (en) * | 2007-05-23 | 2008-12-04 | Allergan, Inc. | Cross-linked collagen and uses thereof |
| US8318695B2 (en) * | 2007-07-30 | 2012-11-27 | Allergan, Inc. | Tunably crosslinked polysaccharide compositions |
| US8697044B2 (en) | 2007-10-09 | 2014-04-15 | Allergan, Inc. | Crossed-linked hyaluronic acid and collagen and uses thereof |
| US8114898B2 (en) | 2007-11-16 | 2012-02-14 | Allergan, Inc. | Compositions and methods for treating purpura |
| US20090143348A1 (en) * | 2007-11-30 | 2009-06-04 | Ahmet Tezel | Polysaccharide gel compositions and methods for sustained delivery of drugs |
| US8394784B2 (en) * | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having multi-stage bioactive agent delivery |
| US8394782B2 (en) * | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having increased longevity |
| WO2009108760A2 (en) | 2008-02-26 | 2009-09-03 | Board Of Regents, The University Of Texas System | Dendritic macroporous hydrogels prepared by crystal templating |
| US8357795B2 (en) | 2008-08-04 | 2013-01-22 | Allergan, Inc. | Hyaluronic acid-based gels including lidocaine |
| AU2009288118B2 (en) | 2008-09-02 | 2014-12-11 | Allergan, Inc. | Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof |
| JP4885245B2 (ja) * | 2009-01-15 | 2012-02-29 | 日本航空電子工業株式会社 | Ｒｄコンバータ及び角度検出装置 |
| WO2010136594A2 (en) * | 2009-05-29 | 2010-12-02 | Symatese | Injectable combination of adrenergic receptor agonists with fillers, for decreasing skin reactions due to injection |
| FR2948286B1 (fr) | 2009-07-27 | 2011-08-26 | Jean-Noel Thorel | Composition injectable associant un agent de comblement et un milieu de croissance des fibroblastes |
| US20110171311A1 (en) * | 2010-01-13 | 2011-07-14 | Allergan Industrie, Sas | Stable hydrogel compositions including additives |
| US20110171286A1 (en) * | 2010-01-13 | 2011-07-14 | Allergan, Inc. | Hyaluronic acid compositions for dermatological use |
| US20110171310A1 (en) * | 2010-01-13 | 2011-07-14 | Allergan Industrie, Sas | Hydrogel compositions comprising vasoconstricting and anti-hemorrhagic agents for dermatological use |
| US9114188B2 (en) | 2010-01-13 | 2015-08-25 | Allergan, Industrie, S.A.S. | Stable hydrogel compositions including additives |
| US20110172180A1 (en) | 2010-01-13 | 2011-07-14 | Allergan Industrie. Sas | Heat stable hyaluronic acid compositions for dermatological use |
| FR2955258A1 (fr) | 2010-01-20 | 2011-07-22 | Biopharmex Holding Ltd | Composition injectable |
| CN102905677A (zh) | 2010-03-12 | 2013-01-30 | 阿勒根工业有限公司 | 用于改善皮肤状况的包含透明质烷聚合物和甘露糖醇的流体组合物 |
| ES2585388T5 (es) | 2010-03-22 | 2019-08-08 | Allergan Inc | Hidrogeles reticulados de polisacárido y proteína-polisacárido para aumento de tejido blando |
| EP2404993A1 (en) * | 2010-07-09 | 2012-01-11 | Merz Pharma GmbH & Co. KGaA | Alginate filler including eukaryotic cells |
| US8697057B2 (en) | 2010-08-19 | 2014-04-15 | Allergan, Inc. | Compositions and soft tissue replacement methods |
| US9005605B2 (en) | 2010-08-19 | 2015-04-14 | Allergan, Inc. | Compositions and soft tissue replacement methods |
| US8883139B2 (en) | 2010-08-19 | 2014-11-11 | Allergan Inc. | Compositions and soft tissue replacement methods |
| US8889123B2 (en) | 2010-08-19 | 2014-11-18 | Allergan, Inc. | Compositions and soft tissue replacement methods |
| WO2012048289A1 (en) | 2010-10-08 | 2012-04-12 | Board Of Regents, The University Of Texas System | Anti-adhesive barrier membrane using alginate and hyaluronic acid for biomedical applications |
| WO2012048283A1 (en) | 2010-10-08 | 2012-04-12 | Board Of Regents, The University Of Texas System | One-step processing of hydrogels for mechanically robust and chemically desired features |
| KR102312056B1 (ko) | 2011-06-03 | 2021-10-12 | 알러간 인더스트리 에스에이에스 | 항산화제를 포함하는 피부 충전제 조성물 |
| US9408797B2 (en) | 2011-06-03 | 2016-08-09 | Allergan, Inc. | Dermal filler compositions for fine line treatment |
| US9393263B2 (en) | 2011-06-03 | 2016-07-19 | Allergan, Inc. | Dermal filler compositions including antioxidants |
| US20130096081A1 (en) | 2011-06-03 | 2013-04-18 | Allergan, Inc. | Dermal filler compositions |
| US20130244943A1 (en) | 2011-09-06 | 2013-09-19 | Allergan, Inc. | Hyaluronic acid-collagen matrices for dermal filling and volumizing applications |
| US9662422B2 (en) | 2011-09-06 | 2017-05-30 | Allergan, Inc. | Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation |
| JP2015533190A (ja) | 2012-10-09 | 2015-11-19 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニＳｉｇｍａ−Ｔａｕ Ｉｎｄｕｓｔｒｉｅ Ｆａｒｍａｃｅｕｔｉｃｈｅ Ｒｉｕｎｉｔｅ Ｓｏｃｉｅｔａ Ｐｅｒ Ａｚｉｏｎｉ | 修飾されたヒアルロン酸誘導体およびその使用 |
| US11565027B2 (en) | 2012-12-11 | 2023-01-31 | Board Of Regents, The University Of Texas System | Hydrogel membrane for adhesion prevention |
| EP3505197B1 (en) | 2012-12-11 | 2023-09-06 | Board of Regents, The University of Texas System | Hydrogel membrane for adhesion prevention |
| KR20160029818A (ko) * | 2013-07-08 | 2016-03-15 | 덴카 주식회사 | 코어 쉘형 가교 히알루론산 겔 입자, 그의 제조 방법 및 의료용 재료 |
| WO2015018461A1 (fr) | 2013-08-09 | 2015-02-12 | Genbiotech | Compositions therapeutiques comprenant d'acide hyaluronique |
| CN105848628B (zh) * | 2013-12-31 | 2020-09-18 | Pb&B公司 | 用于身体重构和身体成形的受控释放脂肪酸组合物 |
| US20150209265A1 (en) * | 2014-01-27 | 2015-07-30 | Allergan Holdings France S.A.S. | Spherical forms of cross-linked hyaluronic acid and methods of use thereof |
| CA2957970A1 (en) | 2014-08-15 | 2016-02-18 | The Johns Hopkins University Technology Ventures | Composite material for tissue restoration |
| WO2016051219A1 (en) | 2014-09-30 | 2016-04-07 | Allergan Industrie, Sas | Stable hydrogel compositions including additives |
| WO2016128783A1 (en) | 2015-02-09 | 2016-08-18 | Allergan Industrie Sas | Compositions and methods for improving skin appearance |
| PL3256179T3 (pl) | 2015-02-13 | 2020-05-18 | Allergan Industrie, Sas | Implanty do kształtowania, uwydatniania lub korygowania cech twarzy takich jak broda |
| KR101781288B1 (ko) * | 2016-01-26 | 2017-09-26 | 서울과학기술대학교 산학협력단 | 친수성 고분자 및 소수성 고분자를 포함하는 하이드로젤 입자 및 그의 제조방법 |
| US11772061B2 (en) | 2016-11-30 | 2023-10-03 | Brown University | Methods of fabricating hyper compliant polymer particles and methods of use and compositions |
| KR101879065B1 (ko) * | 2016-12-12 | 2018-07-17 | 구태훈 | 구형 입자를 갖는 연조직용 필러 및, 그 제조방법 |
| KR102363007B1 (ko) * | 2017-01-18 | 2022-02-14 | 구태훈 | 모노-페이직 ha 필러의 특성과 바이-페이직 ha 필러의 특성을 함께 갖는 ha 필러, 필러 주입에 사용되는 주사기 및, 필러의 제조방법 |
| KR101769739B1 (ko) * | 2017-01-18 | 2017-08-21 | 구태훈 | 모노-페이직 ha 필러의 특성과 바이-페이직 ha 필러의 특성을 함께 갖는 ha 필러, 필러 주입에 사용되는 주사기 및, 필러의 제조방법 |
| US11980700B2 (en) | 2017-03-08 | 2024-05-14 | Alafair Biosciences, Inc. | Hydrogel medium for the storage and preservation of tissue |
| WO2019159182A1 (en) * | 2018-02-18 | 2019-08-22 | G & G Biotechnology Ltd. | Implants with enhanced shell adhesion |
| CA3134480A1 (en) * | 2018-03-29 | 2020-10-03 | Ramesh S. AYYALA | Methods and compositions for delivery of a therapeutic agent |
| EP3787702B1 (en) | 2018-05-03 | 2024-08-07 | CollPlant Ltd. | Dermal fillers and applications thereof |
| IL307979B2 (en) | 2018-05-09 | 2025-08-01 | Univ Johns Hopkins | Nanofiber-hydrogel composites for enhanced soft tissue replacement and regeneration |
| EP3790602A1 (en) | 2018-05-09 | 2021-03-17 | The Johns Hopkins University | Nanofiber-hydrogel composites for cell and tissue delivery |
| CN110575564B (zh) * | 2019-09-30 | 2020-05-08 | 张勇 | 用于医学整形美容的填充物及其制备方法和应用 |
| EP4337274A4 (en) * | 2021-05-13 | 2025-03-19 | Shanghai Qisheng Biological Preparation Co., Ltd. | Hyaluronic acid compositions containing slowly resorbable polymers |
| WO2023030435A1 (en) | 2021-09-01 | 2023-03-09 | Shanghai Qisheng Biological Preparation Co., Ltd. | Cartilage regeneration using injectable, in situ polymerizable collagen compositions containing chondrocytes or stem cells |
| US12304974B2 (en) | 2021-12-28 | 2025-05-20 | Shanghai Qisheng Biological Preparation Co., Ltd. | Hyaluronic acid-collagen copolymer compositions and medical applications thereof |
| CN115721615B (zh) * | 2022-11-17 | 2024-08-30 | 华熙生物科技股份有限公司 | 一种透明质酸颗粒及其制备方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2128827A (en) * | 1938-03-09 | 1938-08-30 | Frank B Killian | Method and apparatus for manufacturing thin rubber articles |
| US5643464A (en) * | 1988-11-21 | 1997-07-01 | Collagen Corporation | Process for preparing a sterile, dry crosslinking agent |
| DK0680525T3 (da) * | 1993-01-20 | 1997-10-20 | Squibb & Sons Inc | Fibre |
| US6214331B1 (en) * | 1995-06-06 | 2001-04-10 | C. R. Bard, Inc. | Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained |
| EP0830416B1 (en) * | 1995-06-06 | 2005-08-31 | C.R. Bard, Inc. | Process for the preparation of crosslinked particles of water soluble polymers, the particles obtained and their use |
| US6007843A (en) * | 1995-09-29 | 1999-12-28 | Lam Pharmaceuticals Corp. | Sustained release delivery system |
| US5935164A (en) * | 1997-02-25 | 1999-08-10 | Pmt Corporaton | Laminated prosthesis and method of manufacture |
| FR2764514B1 (fr) * | 1997-06-13 | 1999-09-03 | Biopharmex Holding Sa | Implant injectable en sous-cutane ou intradermique a bioresorbabilite controlee pour la chirurgie reparatrice ou plastique et la dermatologie esthetique |
| US6767928B1 (en) * | 1999-03-19 | 2004-07-27 | The Regents Of The University Of Michigan | Mineralization and biological modification of biomaterial surfaces |
| US6773723B1 (en) * | 2000-08-30 | 2004-08-10 | Depuy Acromed, Inc. | Collagen/polysaccharide bilayer matrix |
| US6620196B1 (en) * | 2000-08-30 | 2003-09-16 | Sdgi Holdings, Inc. | Intervertebral disc nucleus implants and methods |
| CA2424896A1 (en) * | 2000-10-06 | 2002-04-11 | Jagotec Ag | A controlled-release, parenterally administrable microparticle preparation |
| AU2001298061A1 (en) * | 2000-12-13 | 2003-07-09 | Purdue Research Foundation | Microencapsulation of drugs by solvent exchange |
| US6979440B2 (en) * | 2001-01-29 | 2005-12-27 | Salvona, Llc | Compositions and method for targeted controlled delivery of active ingredients and sensory markers onto hair, skin, and fabric |
| KR20050059003A (ko) * | 2002-07-02 | 2005-06-17 | 프로사이트 코포레이션 | 펩티드 구리 착화합물 및 연조직 충전제를 함유하는조성물 |
| US6780366B2 (en) * | 2002-08-15 | 2004-08-24 | Mentor Corporation | Drip retainer |
| KR100523953B1 (ko) | 2002-08-27 | 2005-10-25 | 주식회사 엘지생명과학 | 천연다당류와 히알루론산의 마이크로비드 및 이의 제조 방법 |
| TWI251596B (en) * | 2002-12-31 | 2006-03-21 | Ind Tech Res Inst | Method for producing a double-crosslinked hyaluronate material |
| US8124120B2 (en) * | 2003-12-22 | 2012-02-28 | Anika Therapeutics, Inc. | Crosslinked hyaluronic acid compositions for tissue augmentation |
| JP2008502690A (ja) * | 2004-06-15 | 2008-01-31 | アンドリュー シァン チェン， | リン脂質組成物ならびにその調製方法および使用方法 |
| EP1726299A3 (en) | 2005-05-27 | 2007-04-18 | StratoSphere Pharma AB | Cores and microcapsules suitable for parenteral administration as well as process for their manufacture |
-
2008
- 2008-05-21 CA CA002687983A patent/CA2687983A1/en not_active Abandoned
- 2008-05-21 US US12/124,722 patent/US20090022808A1/en not_active Abandoned
- 2008-05-21 WO PCT/US2008/064378 patent/WO2008147817A2/en not_active Ceased
- 2008-05-21 JP JP2010509527A patent/JP2010528039A/ja active Pending
- 2008-05-21 BR BRPI0811777A patent/BRPI0811777A2/pt not_active IP Right Cessation
- 2008-05-21 EP EP08769563A patent/EP2162158A2/en not_active Withdrawn
- 2008-05-21 AU AU2008256864A patent/AU2008256864A1/en not_active Abandoned
-
2010
- 2010-03-31 US US12/751,202 patent/US20100217403A1/en not_active Abandoned
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