JP2010527980A5 - - Google Patents

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Publication number
JP2010527980A5
JP2010527980A5 JP2010508908A JP2010508908A JP2010527980A5 JP 2010527980 A5 JP2010527980 A5 JP 2010527980A5 JP 2010508908 A JP2010508908 A JP 2010508908A JP 2010508908 A JP2010508908 A JP 2010508908A JP 2010527980 A5 JP2010527980 A5 JP 2010527980A5
Authority
JP
Japan
Prior art keywords
alkyl
aryl
acceptable salt
pharmaceutically acceptable
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010508908A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010527980A (ja
Filing date
Publication date
Priority claimed from GB0709789A external-priority patent/GB0709789D0/en
Priority claimed from GB0800454A external-priority patent/GB0800454D0/en
Application filed filed Critical
Priority claimed from PCT/GB2008/050370 external-priority patent/WO2008142454A1/en
Publication of JP2010527980A publication Critical patent/JP2010527980A/ja
Publication of JP2010527980A5 publication Critical patent/JP2010527980A5/ja
Pending legal-status Critical Current

Links

JP2010508908A 2007-05-22 2008-05-22 代謝障害を治療するための二環状アリールおよびヘテロアリール化合物 Pending JP2010527980A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0709789A GB0709789D0 (en) 2007-05-22 2007-05-22 Compounds
GB0800454A GB0800454D0 (en) 2008-01-11 2008-01-11 Compounds
PCT/GB2008/050370 WO2008142454A1 (en) 2007-05-22 2008-05-22 Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders

Publications (2)

Publication Number Publication Date
JP2010527980A JP2010527980A (ja) 2010-08-19
JP2010527980A5 true JP2010527980A5 (en:Method) 2011-07-07

Family

ID=39643985

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010508908A Pending JP2010527980A (ja) 2007-05-22 2008-05-22 代謝障害を治療するための二環状アリールおよびヘテロアリール化合物

Country Status (4)

Country Link
US (1) US8278442B2 (en:Method)
EP (1) EP2152671A1 (en:Method)
JP (1) JP2010527980A (en:Method)
WO (1) WO2008142454A1 (en:Method)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2152671A1 (en) 2007-05-22 2010-02-17 Prosidion Limited Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders
EP2197835A1 (en) * 2007-09-07 2010-06-23 Prosidion Limited Bicyclic aryl and heteroaryl receptor modulators
WO2012090177A2 (en) * 2010-12-30 2012-07-05 Lupin Limited Cannabinoid receptor modulators
IN2014MN00226A (en:Method) * 2011-07-05 2015-09-25 Lupin Ltd
US10273234B2 (en) * 2012-08-06 2019-04-30 Biogen Ma Inc. Compounds that are S1P modulating agents and/or ATX modulating agents
WO2015076310A1 (ja) 2013-11-20 2015-05-28 株式会社 三和化学研究所 新規３－アザビシクロ［３．１．０］ヘキサン誘導体及びその医薬用途
EP3186224B1 (en) * 2014-08-27 2021-04-21 F. Hoffmann-La Roche AG Substituted azetidine derivatives as taar ligands
WO2016185032A1 (en) * 2015-05-20 2016-11-24 Integrative Research Laboratories Sweden Ab Novel azetidine derivatives useful as modulators of cortical cathecolaminergic neurotransmission
CN105330616B (zh) * 2015-12-09 2017-09-26 苏州明锐医药科技有限公司 卡利拉嗪的制备方法
KR20190096949A (ko) 2016-10-05 2019-08-20 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 소분자 ampk 활성화제
CN106588842A (zh) * 2016-12-05 2017-04-26 天津羲泽润科技有限公司 一种合成7‑甲氧基‑1‑苯并呋喃‑4‑甲醛的方法
AU2020345766A1 (en) 2019-09-10 2022-03-03 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods and materials for increasing level of phosphorylated AMPK protein
WO2023165874A1 (en) * 2022-03-01 2023-09-07 Syngenta Crop Protection Ag Pyrimidinyl-oxy-quinoline based herbicidal compounds

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6225080B1 (en) 1992-03-23 2001-05-01 George R. Uhl Mu-subtype opioid receptor
US6235496B1 (en) 1993-03-08 2001-05-22 Advanced Research & Technology Institute Nucleic acid encoding mammalian mu opioid receptor
US5658783A (en) 1993-11-08 1997-08-19 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University, A Non-Profit Organization Mammalian methadone-specific opioid receptor gene and uses
US5821219A (en) 1995-08-11 1998-10-13 Oregon Health Sciences University Opioid antagonists and methods of their use
ATE308522T1 (de) 2002-05-30 2005-11-15 Lilly Co Eli Opioidrezeptorantagonisten
ES2305491T3 (es) 2002-09-19 2008-11-01 Eli Lilly And Company Eteres de diarilo como antagonistas de receptores de opioides.
ES2294475T3 (es) * 2003-03-07 2008-04-01 Eli Lilly And Company Derivados de nicotinamida g-sustituidos como antagonistas de receptores de opioides.
DE602004016127D1 (de) 2003-03-07 2008-10-09 Lilly Co Eli Antagonisten der opioidrezeptoren
CA2549009A1 (en) 2003-12-12 2005-07-07 Eli Lilly And Company Opioid receptor antagonists
EP1699783B1 (en) 2003-12-22 2012-07-25 Eli Lilly And Company Opioid receptor antagonists
DE602005022572D1 (de) 2004-03-12 2010-09-09 Lilly Co Eli Antagonisten des opioidrezeptors
WO2005090337A1 (en) 2004-03-12 2005-09-29 Eli Lilly And Company Opioid receptor antagonists
CA2558030A1 (en) 2004-03-15 2005-09-29 Eli Lilly And Company 4- (5- (aminomethyl) -indole-1-ylmethyl) -benzamide derivatives and related compounds as opioid receptor antagonists for the treatment of obesity
US7378448B2 (en) 2004-03-15 2008-05-27 Eli Lilly And Company Diphenylether amide derivatives as opioid receptor antagonists
WO2007047397A2 (en) 2005-10-13 2007-04-26 Smithkline Beecham Corporation Phenol ethers as modulators of the opioid receptors
US20100222345A1 (en) 2006-08-09 2010-09-02 Caroline Jean Diaz Novel compounds as antagonists or inverse agonists for opioid receptors
WO2008021849A2 (en) 2006-08-09 2008-02-21 Smithkline Beecham Corporation Novel compounds as antagonists or inverse agonists at opioid receptors
EP2064199A1 (en) 2006-09-08 2009-06-03 Pfizer Products Inc. Diaryl ether derivatives and uses thereof
MX2009004314A (es) 2006-11-13 2009-05-05 Pfizer Prod Inc Diaril, dipiridinil y arilpiridinilderivados y usos de los mismos.
EP2152671A1 (en) 2007-05-22 2010-02-17 Prosidion Limited Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders
US20100113512A1 (en) 2008-10-30 2010-05-06 Diane Michele Ignar Method of treatment using novel antagonists or inverse agonists at opioid receptors

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