JP2010527372A - ペプチドを放出する生分解性ポリマー - Google Patents

ペプチドを放出する生分解性ポリマー Download PDF

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Publication number
JP2010527372A
JP2010527372A JP2010508553A JP2010508553A JP2010527372A JP 2010527372 A JP2010527372 A JP 2010527372A JP 2010508553 A JP2010508553 A JP 2010508553A JP 2010508553 A JP2010508553 A JP 2010508553A JP 2010527372 A JP2010527372 A JP 2010527372A
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peptide
factor
interleukin
agent
biodegradable composition
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Japanese (ja)
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JP2010527372A5 (https=
Inventor
ジョシュア ストペック,
ブライアン クエバス,
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タイコ ヘルスケア グループ リミテッド パートナーシップ
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Publication of JP2010527372A publication Critical patent/JP2010527372A/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593Polyesters, e.g. PLGA or polylactide-co-glycolide
    • AHUMAN NECESSITIES
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    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • A61L2300/604Biodegradation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Materials Engineering (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
JP2010508553A 2007-05-14 2008-05-14 ペプチドを放出する生分解性ポリマー Pending JP2010527372A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93011007P 2007-05-14 2007-05-14
PCT/US2008/063571 WO2008141326A1 (en) 2007-05-14 2008-05-14 Biodegradable peptide releasing polymers

Publications (2)

Publication Number Publication Date
JP2010527372A true JP2010527372A (ja) 2010-08-12
JP2010527372A5 JP2010527372A5 (https=) 2012-05-24

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ID=40002653

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JP2010508553A Pending JP2010527372A (ja) 2007-05-14 2008-05-14 ペプチドを放出する生分解性ポリマー

Country Status (6)

Country Link
US (1) US8974776B2 (https=)
EP (1) EP2150202B1 (https=)
JP (1) JP2010527372A (https=)
AU (1) AU2008251338B2 (https=)
CA (1) CA2686068A1 (https=)
WO (1) WO2008141326A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013039190A1 (ja) * 2011-09-15 2013-03-21 和歌山県 ペプチド含有ポリマー、及び繊維へのペプチド固定化方法
US8605675B2 (en) 2008-01-04 2013-12-10 Qualcomm Incorporated Resource allocation for enhanced uplink using an acquisition indicator channel
JP2017528296A (ja) * 2014-09-18 2017-09-28 コンドロネスト・ソシエテ・アノニム グリコサミノグリカンおよびタンパク質を含む組成物

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PL220297B1 (pl) * 2012-11-07 2015-10-30 Wrocławskie Ct Badań Eit & Spółka Z Ograniczoną Odpowiedzialności& Epitop i jego zastosowanie
US10058352B2 (en) 2012-11-08 2018-08-28 Smith & Nephew, Inc. Methods and devices suitable for improved reattachment of detached cartilage to subchondral bone
US9827345B2 (en) * 2012-11-08 2017-11-28 Smith & Nephew, Inc. Methods and compositions suitable for improved reattachment of detached cartilage to subchondral bone
AU2014354793B2 (en) * 2013-11-26 2018-04-05 Avent, Inc. Foams for oxygen delivery to wounds
US9987289B2 (en) * 2015-07-10 2018-06-05 Warsaw Orthopedic, Inc. Slow release oxysterols and methods of use
WO2018048192A1 (ko) * 2016-09-07 2018-03-15 부산대학교병원 종양 특이적 효소 응답형 나노섬유가 코팅된 보리노스탯 방출형 소화관 스텐트 및 그 제조방법
CN109608646B (zh) * 2018-11-21 2021-03-16 深圳市孙逸仙心血管医院(深圳市心血管病研究所) 一种靶向治疗心肌损伤的纳米载体及应用
US12383246B2 (en) 2020-10-12 2025-08-12 Abbott Cardiovascular Systems, Inc. Vessel closure device with improved safety and tract hemostasis
CN114404601B (zh) * 2022-03-31 2022-06-07 首都医科大学附属北京朝阳医院 MDK抑制剂在制备用于抑制干扰素-γ治疗引起的肿瘤转移的药物中的应用

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JPH11192299A (ja) * 1997-12-29 1999-07-21 Takiron Co Ltd 生体内分解吸収性可塑性粘着物
JP2002526383A (ja) * 1998-05-16 2002-08-20 モガン バイオテクノロジー リサーチ インスティチュート 薬物分子と生分解性高分子の共有結合を用いた薬物分子伝達システム
JP2002535426A (ja) * 1999-01-26 2002-10-22 ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス 生物分解性ポリエステルおよび生物活性ポリペプチドのイオン分子結合体
JP2004526043A (ja) * 2001-05-07 2004-08-26 コーネル・リサーチ・ファンデーション・インコーポレイテッド 複数の官能基を有するセグメントに結合した生物分解性のコポリマー
JP2005516091A (ja) * 2001-10-22 2005-06-02 マサチューセッツ インスティテュート オブ テクノロジー 生分解性ポリマー
WO2006078356A1 (en) * 2005-01-14 2006-07-27 Advanced Cardiovascular Systems, Inc. Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles
JP2006520217A (ja) * 2003-02-26 2006-09-07 メディバス エルエルシー 生物活性ステントおよびその使用方法

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US5510418A (en) * 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
NL9101002A (nl) 1991-06-11 1993-01-04 Dsm Nv Copolymeren op basis van cyclische esters.
US20020041898A1 (en) * 2000-01-05 2002-04-11 Unger Evan C. Novel targeted delivery systems for bioactive agents
US20050063937A1 (en) 2003-09-16 2005-03-24 Cheng Li Multiple-arm peptide compounds, methods of manufacture and use in therapy
MXPA06010782A (es) 2004-03-23 2007-03-28 Complex Biosystems Gmbh Ligador de profarmaco.
US20050281866A1 (en) 2004-05-24 2005-12-22 Genzyme Corporation Adherent polymeric compositions

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11192299A (ja) * 1997-12-29 1999-07-21 Takiron Co Ltd 生体内分解吸収性可塑性粘着物
JP2002526383A (ja) * 1998-05-16 2002-08-20 モガン バイオテクノロジー リサーチ インスティチュート 薬物分子と生分解性高分子の共有結合を用いた薬物分子伝達システム
JP2002535426A (ja) * 1999-01-26 2002-10-22 ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス 生物分解性ポリエステルおよび生物活性ポリペプチドのイオン分子結合体
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JP2005516091A (ja) * 2001-10-22 2005-06-02 マサチューセッツ インスティテュート オブ テクノロジー 生分解性ポリマー
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JP2017528296A (ja) * 2014-09-18 2017-09-28 コンドロネスト・ソシエテ・アノニム グリコサミノグリカンおよびタンパク質を含む組成物

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EP2150202A4 (en) 2012-08-22
WO2008141326A1 (en) 2008-11-20
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US8974776B2 (en) 2015-03-10
US20100297066A1 (en) 2010-11-25

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