JP2010524963A5 - - Google Patents

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Publication number
JP2010524963A5
JP2010524963A5 JP2010504247A JP2010504247A JP2010524963A5 JP 2010524963 A5 JP2010524963 A5 JP 2010524963A5 JP 2010504247 A JP2010504247 A JP 2010504247A JP 2010504247 A JP2010504247 A JP 2010504247A JP 2010524963 A5 JP2010524963 A5 JP 2010524963A5
Authority
JP
Japan
Prior art keywords
ion
pairing agent
lipoic acid
pharmaceutical formulation
item
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010504247A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010524963A (ja
JP5480804B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/060650 external-priority patent/WO2008131114A2/en
Publication of JP2010524963A publication Critical patent/JP2010524963A/ja
Publication of JP2010524963A5 publication Critical patent/JP2010524963A5/ja
Application granted granted Critical
Publication of JP5480804B2 publication Critical patent/JP5480804B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010504247A 2007-04-18 2008-04-17 リポ酸誘導体を含有する医薬製剤 Expired - Fee Related JP5480804B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91260507P 2007-04-18 2007-04-18
US60/912,605 2007-04-18
PCT/US2008/060650 WO2008131114A2 (en) 2007-04-18 2008-04-17 Pharmaceutical formulations containing lipoic acid derivatives

Publications (3)

Publication Number Publication Date
JP2010524963A JP2010524963A (ja) 2010-07-22
JP2010524963A5 true JP2010524963A5 (OSRAM) 2012-05-31
JP5480804B2 JP5480804B2 (ja) 2014-04-23

Family

ID=39872894

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010504247A Expired - Fee Related JP5480804B2 (ja) 2007-04-18 2008-04-17 リポ酸誘導体を含有する医薬製剤

Country Status (19)

Country Link
US (4) US20080262077A1 (OSRAM)
EP (1) EP2144609B1 (OSRAM)
JP (1) JP5480804B2 (OSRAM)
KR (1) KR101539785B1 (OSRAM)
CN (1) CN101820875B (OSRAM)
AR (1) AR067309A1 (OSRAM)
AU (1) AU2008242827B2 (OSRAM)
BR (1) BRPI0810439B1 (OSRAM)
CA (1) CA2684479C (OSRAM)
CL (1) CL2008001124A1 (OSRAM)
ES (1) ES2528414T3 (OSRAM)
IL (1) IL201581A (OSRAM)
MX (1) MX2009011165A (OSRAM)
NZ (1) NZ580973A (OSRAM)
PL (1) PL2144609T3 (OSRAM)
PT (1) PT2144609E (OSRAM)
SA (1) SA08290240B1 (OSRAM)
TW (1) TWI459944B (OSRAM)
WO (1) WO2008131114A2 (OSRAM)

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CA2684480A1 (en) * 2007-04-18 2008-10-30 Cornerstone Pharmaceuticals, Inc. Lipoic acid derivatives useful in the treatment of cancer
US8263653B2 (en) 2007-04-18 2012-09-11 Cornerstone Pharmaceuticals, Inc. Pharmaceutical formulations containing lipoic acid derivatives
JP5480804B2 (ja) 2007-04-18 2014-04-23 コーナーストーン ファーマシューティカルズ，インコーポレーテッド リポ酸誘導体を含有する医薬製剤
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KR20110025168A (ko) * 2008-04-04 2011-03-09 로버트 쇼어 약학적 조성물
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WO2010110771A2 (en) * 2009-03-25 2010-09-30 Frank Gibson Substituted thiol-containing alkyl fatty acids and process for synthesizing derivatives thereof
DK3338765T3 (en) 2009-12-01 2019-03-04 Translate Bio Inc STEROID DERIVATIVE FOR THE SUPPLY OF MRNA IN HUMANGENETIC DISEASES
WO2011143593A1 (en) * 2010-05-14 2011-11-17 Cornerstone Pharmaceuticals, Inc. Conjugates of a lipoic acid derivative and anti-proliferation agent and medical uses thereof
WO2011143590A1 (en) * 2010-05-14 2011-11-17 Cornerstone Pharmaceuticals, Inc. Combination therapy compositions and methods using lipoic acid derivatives and an anti-proliferation agent
JP6184945B2 (ja) 2011-06-08 2017-08-23 シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド ｍＲＮＡ送達のための脂質ナノ粒子組成物および方法
CN102657606B (zh) * 2012-05-25 2014-01-01 江苏神龙药业有限公司 一种供静脉给药用的硫辛酸注射液
EP3536787A1 (en) 2012-06-08 2019-09-11 Translate Bio, Inc. Nuclease resistant polynucleotides and uses thereof
AU2013364387B2 (en) * 2012-12-19 2018-07-19 Paul Bingham Pharmaceutical compounds
IL305374A (en) 2013-03-14 2023-10-01 Ethris Gmbh Cftr mrna compositions and related methods and uses
JP6586075B2 (ja) 2013-03-14 2019-10-02 トランスレイト バイオ， インコーポレイテッド メッセンジャーｒｎａの精製方法
CN103360437B (zh) * 2013-04-27 2015-10-21 江苏教育学院 一种硫辛酸糖类衍生物及其制备方法和在制备抗肿瘤药物中的应用
CN103497344B (zh) * 2013-09-25 2015-09-23 深圳先进技术研究院 用于负载贵金属颗粒的纳米凝胶及其制备方法与应用
BR112016009014B1 (pt) 2013-10-22 2024-02-06 Translate Bio, Inc USO DE COMPOSIÇÃO COMPREENDENDO mRNA PARA DEFICIÊNCIA DE ARGININOSSUCINATO SINTETASE
EA034103B1 (ru) 2013-10-22 2019-12-27 Транслейт Био, Инк. СПОСОБ ЛЕЧЕНИЯ ФЕНИЛКЕТОНУРИИ С ПРИМЕНЕНИЕМ мРНК
MX373952B (es) 2014-04-25 2020-07-13 Shire Human Genetic Therapies Métodos de purificación de arn mensajero.
EP3188726B1 (en) 2014-06-19 2019-08-07 Rafael Pharmaceuticals, Inc. Pharmaceutical compounds
CA2965963A1 (en) * 2014-06-19 2015-12-23 Robert Shorr Lipoic acid derivatives for pharmaceutical use
EP3585417B1 (en) 2017-02-27 2023-02-22 Translate Bio, Inc. Method of making a codon-optimized cftr mrna
EP3624824B1 (en) 2017-05-16 2024-07-10 Translate Bio, Inc. Codon-optimized mrna encoding cftr for use in treating cystic fibrosis
CA3108544A1 (en) 2018-08-24 2020-02-27 Translate Bio, Inc. Methods for purification of messenger rna
AU2019384557B2 (en) 2018-11-21 2025-07-17 Translate Bio, Inc. Treatment of cystic fibrosis by delivery of nebulized mRNA encoding CFTR
TW202114651A (zh) * 2019-08-16 2021-04-16 美商拉斐爾製藥公司 用於治療癌症之方法及含有４，６—雙（苄硫基）己酸之藥物組成物
EP4110308A4 (en) * 2020-02-28 2024-03-20 University Of Florida Research Foundation, Incorporated ANTI-TUMOR IMMUNITY MODULATING COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
CN116710072A (zh) * 2020-11-03 2023-09-05 基石制药股份有限公司 使用德维司他治疗胆道癌的治疗方法和组合物
CN119770650A (zh) * 2025-01-09 2025-04-08 华中科技大学 一种硫辛酸-胆碱离子液体溶液及其制备方法和应用

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CA2684480A1 (en) * 2007-04-18 2008-10-30 Cornerstone Pharmaceuticals, Inc. Lipoic acid derivatives useful in the treatment of cancer
US8263653B2 (en) * 2007-04-18 2012-09-11 Cornerstone Pharmaceuticals, Inc. Pharmaceutical formulations containing lipoic acid derivatives
JP5480804B2 (ja) 2007-04-18 2014-04-23 コーナーストーン ファーマシューティカルズ，インコーポレーテッド リポ酸誘導体を含有する医薬製剤

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