JP2010523138A - 免疫原性組成物 - Google Patents

免疫原性組成物 Download PDF

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Publication number
JP2010523138A
JP2010523138A JP2010502570A JP2010502570A JP2010523138A JP 2010523138 A JP2010523138 A JP 2010523138A JP 2010502570 A JP2010502570 A JP 2010502570A JP 2010502570 A JP2010502570 A JP 2010502570A JP 2010523138 A JP2010523138 A JP 2010523138A
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Prior art keywords
antigen
vector
immunogenic composition
viral vector
c4bp
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JP2010502570A
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Japanese (ja)
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JP2010523138A5 (enExample
Inventor
サイモン ドレイパー,
エイドリアン ヒル,
ファーガル ヒル,
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Imaxio SA
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Imaxio SA
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    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/002Protozoa antigens
    • A61K39/015Hemosporidia antigens, e.g. Plasmodium antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
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    • A61P31/20Antivirals for DNA viruses
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55516Proteins; Peptides
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    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
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  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2010502570A 2007-04-10 2008-04-10 免疫原性組成物 Pending JP2010523138A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0706912.3A GB0706912D0 (en) 2007-04-10 2007-04-10 Novel viral vaccines
PCT/GB2008/001271 WO2008122817A2 (en) 2007-04-10 2008-04-10 Immunogenic compositions

Publications (2)

Publication Number Publication Date
JP2010523138A true JP2010523138A (ja) 2010-07-15
JP2010523138A5 JP2010523138A5 (enExample) 2011-05-19

Family

ID=38091118

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010502570A Pending JP2010523138A (ja) 2007-04-10 2008-04-10 免疫原性組成物

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US (1) US20110064768A1 (enExample)
EP (1) EP2155242A2 (enExample)
JP (1) JP2010523138A (enExample)
CN (1) CN101959420A (enExample)
AU (1) AU2008235315A1 (enExample)
CA (1) CA2683117A1 (enExample)
GB (1) GB0706912D0 (enExample)
WO (1) WO2008122817A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0719509D0 (en) * 2007-10-05 2007-11-14 Isis Innovation Molecular adjuvant
BRPI0924581A2 (pt) * 2009-05-05 2016-07-19 Univ Minas Gerais seqüências geneticamente modificadas de antígenos de plasmodium vivax, composições vacinais contendo proteínas recombinantes e vírus recombinantes que expressam esses antígenos e método de vacinação dose-reforço contra malária
GB0918154D0 (en) 2009-10-16 2009-12-02 Isis Innovation Mycobacterial vaccines
EP2557089A2 (en) * 2011-07-15 2013-02-13 Fundació Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) Compositions and methods for immunomodulation
WO2014090905A1 (en) 2012-12-11 2014-06-19 Imaxio Modified coiled coil type proteins having improved properties
CN105744950A (zh) * 2013-11-05 2016-07-06 巴法里安诺迪克有限公司 用于使用表达肿瘤抗原的痘病毒和免疫检查点抑制剂的拮抗剂和/或激动剂治疗癌症的组合疗法
SG10201901735XA (en) * 2014-09-03 2019-03-28 Bavarian Nordic As Recombinant modified vaccinia virus ankara (mva) filovirus vaccine

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002506346A (ja) * 1997-06-09 2002-02-26 オクソン・ファーマクシンズ・リミテッド Cd8 t細胞免疫応答を発生するワクチン接種のための方法および試薬
JP2003509470A (ja) * 1999-09-21 2003-03-11 アイシス イノヴェイション リミテッド 抗原に対するcd8+t細胞免疫応答を増強するための複製欠損性アデノウイルスベクターの使用
WO2005014654A2 (en) * 2003-08-12 2005-02-17 Avidis Sa Product comprising a c4bp core protein and a monomeric antigen, and its use
WO2005051414A1 (en) * 2003-11-26 2005-06-09 Avidis Sa Use of c4bp core region as a cd40 agonist

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2678797A (en) * 1996-04-22 1997-11-12 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Heterologous boosting immunizations
EP1450854A2 (en) * 2001-11-30 2004-09-01 Isis Innovation Limited Vaccine
JP2006503800A (ja) * 2002-03-13 2006-02-02 メルク エンド カムパニー インコーポレーテッド Hivに対する強化された免疫応答を誘導する方法
EP1795540A1 (en) * 2005-11-30 2007-06-13 Imaxio Multimeric complexes of antigens and an adjuvant

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002506346A (ja) * 1997-06-09 2002-02-26 オクソン・ファーマクシンズ・リミテッド Cd8 t細胞免疫応答を発生するワクチン接種のための方法および試薬
JP2003509470A (ja) * 1999-09-21 2003-03-11 アイシス イノヴェイション リミテッド 抗原に対するcd8+t細胞免疫応答を増強するための複製欠損性アデノウイルスベクターの使用
WO2005014654A2 (en) * 2003-08-12 2005-02-17 Avidis Sa Product comprising a c4bp core protein and a monomeric antigen, and its use
WO2005051414A1 (en) * 2003-11-26 2005-06-09 Avidis Sa Use of c4bp core region as a cd40 agonist

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JPN6013015445; Nature Medicine, 2003, Vol.9, No.6, p.729-735 *
JPN6013015446; Vaccine, 2002, Vol.20, p.1039-1045 *
JPN6013015447; Proc. Natl. Acad. Sci. USA, 2001, Vol.98, No.20, p.11491-11496 *
JPN6013015448; Vaccine, 2003, Vol.21, p.1432-1444 *

Also Published As

Publication number Publication date
US20110064768A1 (en) 2011-03-17
CN101959420A (zh) 2011-01-26
WO2008122817A3 (en) 2008-12-11
CA2683117A1 (en) 2008-10-16
EP2155242A2 (en) 2010-02-24
GB0706912D0 (en) 2007-05-16
AU2008235315A1 (en) 2008-10-16
WO2008122817A2 (en) 2008-10-16

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